RU93058676A - ORAL TREATMENT OF HELICOBACTERIAL INFECTION - Google Patents

ORAL TREATMENT OF HELICOBACTERIAL INFECTION

Info

Publication number
RU93058676A
RU93058676A RU93058676/14A RU93058676A RU93058676A RU 93058676 A RU93058676 A RU 93058676A RU 93058676/14 A RU93058676/14 A RU 93058676/14A RU 93058676 A RU93058676 A RU 93058676A RU 93058676 A RU93058676 A RU 93058676A
Authority
RU
Russia
Prior art keywords
infection
helicobacter
host
helicobacterial
treatment
Prior art date
Application number
RU93058676/14A
Other languages
Russian (ru)
Other versions
RU2107513C1 (en
Inventor
Стивен Джеймс Чинн
Джон Гилберт Недруд
Original Assignee
Стивен Джеймс Чинн
Джон Гилберт Недруд
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Стивен Джеймс Чинн, Джон Гилберт Недруд filed Critical Стивен Джеймс Чинн
Priority claimed from PCT/US1993/003409 external-priority patent/WO1993020843A1/en
Publication of RU93058676A publication Critical patent/RU93058676A/en
Application granted granted Critical
Publication of RU2107513C1 publication Critical patent/RU2107513C1/en

Links

Claims (1)

Изобретение относится к лечению желудочной инфекции у млекопитающих, в частности к методам лечения геликобактерной инфекции, к составам вакцин и к антителам, пригодным для использования при таком лечении. Заявляемый способ вызывания у "хозяина" защитной иммунной реакции на инфекцию Геликобактер, заключается в введении в "хозяина" иммуногенически эффективного количества антигена Геликобактер для использования при получении указанной защитной реакции у человека. Вакцина для лечения инфекции Геликобактер включает в себя иммуногенически эффективное количество антигена. Геликобактер в ассоциации с фармацевтически приемлемым носителем или разбавителем. Задача изобретения - создание способа вызывания иммунной реакции у млекопитающих, обеспечивающей защитные функции от геликобактерной инфекции.The invention relates to the treatment of gastric infection in mammals, in particular to methods for treating Helicobacter pylori infection, to vaccine formulations and to antibodies suitable for use in such treatment. The inventive method of inducing a protective host immune response to Helicobacter infection in a “host” is to introduce an immunogenically effective amount of Helicobacter antigen into the “host” for use in obtaining said protective reaction in humans. Helicobacter infection vaccine includes an immunogenically effective amount of antigen. Helicobacter in association with a pharmaceutically acceptable carrier or diluent. The objective of the invention is the creation of a method of inducing an immune response in mammals, providing protective functions against helicobacter infection.
RU93058676A 1992-04-13 1993-04-09 Oral treatment of helicobacter infection RU2107513C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86828692A 1992-04-13 1992-04-13
US868286 1992-04-13
PCT/US1993/003409 WO1993020843A1 (en) 1992-04-13 1993-04-09 Oral treatment of helicobacter infection

Publications (2)

Publication Number Publication Date
RU93058676A true RU93058676A (en) 1997-02-10
RU2107513C1 RU2107513C1 (en) 1998-03-27

Family

ID=25351374

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93058676A RU2107513C1 (en) 1992-04-13 1993-04-09 Oral treatment of helicobacter infection

Country Status (17)

Country Link
US (1) US5538729A (en)
EP (1) EP0590138A4 (en)
JP (1) JPH07500845A (en)
BG (1) BG61935B1 (en)
BR (1) BR9305482A (en)
CA (1) CA2111189A1 (en)
CZ (1) CZ273093A3 (en)
FI (1) FI935591A (en)
HU (1) HU214699B (en)
MX (1) MX9301706A (en)
NO (1) NO934547D0 (en)
NZ (1) NZ251849A (en)
OA (1) OA10213A (en)
RU (1) RU2107513C1 (en)
SG (1) SG52556A1 (en)
SK (1) SK281238B6 (en)
WO (1) WO1993020843A1 (en)

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US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
MX9301706A (en) * 1992-04-13 1994-05-31 Oravax Inc VACCINE COMPOSITION FOR THE TREATMENT OF HELICOBACTER INFECTION.
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
US5843460A (en) * 1993-05-19 1998-12-01 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
WO1995014093A1 (en) 1993-05-19 1995-05-26 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions and nucleic acid sequences encoding said polypeptides
KR100333113B1 (en) * 1993-07-27 2002-11-27 시에스엘 리미티드 Treatment of h. pylori associated gastroduodenal disease
US6406703B1 (en) 1993-07-27 2002-06-18 Csl Limited Treatment of H. pylori associated gastroduodenal disease
AUPM399594A0 (en) 1994-02-21 1994-03-17 Csl Limited Antigenic preparation for treatment or prevention of helicobacter infection
US5780040A (en) * 1994-06-08 1998-07-14 Tufts University School Of Medicine Hospital, Inc. Helicobacter pylori nickel binding protein
AUPM612494A0 (en) 1994-06-08 1994-06-30 Csl Limited Treatment or prevention of helicobacter infection
AU702878B2 (en) * 1994-06-08 1999-03-11 Csl Limited Treatment and prevention of helicobacter infection
JPH10502365A (en) * 1994-07-01 1998-03-03 リカン・リミテッド Helicobacter proteins and vaccines
SG90030A1 (en) * 1994-10-05 2002-07-23 Microcarb Inc Methods for producing enhanced antigenic helocobacter sp. and vaccines comprising same
US5897475A (en) * 1994-10-05 1999-04-27 Antex Biologics, Inc. Vaccines comprising enhanced antigenic helicobacter spp.
FR2732605B1 (en) * 1995-04-07 1997-05-16 Pasteur Merieux Serums Vacc COMPOSITION FOR INDUCING MUCOSAL IMMUNE RESPONSE
AR003125A1 (en) * 1995-06-01 1998-07-08 Astra Ab BACTERIAL ANTIGENS FOR THE DIAGNOSIS OF INFECTIONS WITH HELICOBACTER PYLORI, A DNA MOLECLE THAT CODES IT, A VECTOR, A HOST CELL, A PROCEDURE FOR PRODUCING THE POLIPEPTIDE, USE OF ELEPIPETICO, AND PROAPILY USE
EP0797585A1 (en) * 1995-10-09 1997-10-01 Pasteur Merieux Serums Et Vaccins Helicobacter lactoferrin receptor
GB2307987A (en) * 1995-12-06 1997-06-11 Univ Manchester Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto
EP0876476A4 (en) * 1995-12-19 2001-04-18 Univ Iowa State Res Found Inc Heterophil-adapted poultry vaccine
GB2324093A (en) * 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
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WO1998043479A1 (en) * 1997-04-01 1998-10-08 Merieux Oravax 76 kDa, 32 kDa, AND 50 kDa HELICOBACTER POLYPEPTIDES AND CORRESPONDING POLYNUCLEOTIDE MOLECULES
US20020026035A1 (en) * 1997-04-01 2002-02-28 Harold Kleanthous Helicobacter ghpo 1360 and ghpo 750 polypeptides and corresponding polynucleotide molecules
US20030124141A1 (en) * 1997-04-01 2003-07-03 Rainer Haas Helicobacter polypeptides and corresponding polynucleotide molecules
JP3430853B2 (en) 1997-04-11 2003-07-28 株式会社ゲン・コーポレーション Preventive and therapeutic agents for gastritis, gastric ulcer and duodenal ulcer
SE9702240D0 (en) * 1997-06-12 1997-06-12 Astra Ab Vaccine compositions III
KR100509817B1 (en) * 1997-06-27 2005-12-16 씨제이 주식회사 Oral vaccine for prevention of vibrio vulnificus infection
US20030158396A1 (en) * 1997-07-29 2003-08-21 Harold Kleanthous Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome
US6599509B2 (en) * 1997-09-02 2003-07-29 Massachusetts Institute Of Technology Compositions and methods comprising helicobacter antigens for treatment and prevention of inflammatory bowel disease
US5985631A (en) * 1997-09-12 1999-11-16 Oravax-Merieux Co. Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease
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US6585975B1 (en) * 1998-04-30 2003-07-01 Acambis, Inc. Use of Salmonella vectors for vaccination against helicobacter infection
CA2335487A1 (en) 1998-06-19 1999-12-23 Merieux Oravax Lt and ct in parenteral immunization methods against helicobacter infection
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
US20020107368A1 (en) * 2000-12-07 2002-08-08 Jing-Hui Tian Helicobacter proteins, gene sequences and uses thereof
JP2005506322A (en) * 2001-08-31 2005-03-03 カイロン ソチエタ ア レスポンサビリタ リミタータ Helicobacter pylori vaccination
ATE516817T1 (en) * 2005-06-16 2011-08-15 Univ Gent VACCINES FOR IMMUNIZATION AGAINST HELICOBACTER
US7790143B2 (en) * 2005-06-16 2010-09-07 Universiteit Gent Vaccines for immunization against helicobacter

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DE4139840B4 (en) * 1990-12-04 2005-06-02 Quidel Corp., San Diego Antigen preparation for the detection of H. pylori
EP0582672A4 (en) 1991-04-26 1994-06-29 Emanuel Calenoff Methods to detect and treat diseases caused by bacterial allergens
FR2682122B1 (en) * 1991-10-03 1995-06-09 Pasteur Institut NEW GENES OF HELICOBACTER PYLORI. THEIR USE FOR THE PREPARATION OF RECOMBINANT STRAINS OF H. PYLORI.
ATE273021T1 (en) * 1992-02-26 2004-08-15 Univ Vanderbilt PURIFIED VACUOLIZING TOXIN FROM HELICOBACTER PYLORI AND METHODS OF USE THEREOF
JP3368902B2 (en) * 1992-03-02 2003-01-20 カイロン エセ．ピー．アー． Helicobacter pylori proteins useful for vaccines and diagnostics
MX9301706A (en) * 1992-04-13 1994-05-31 Oravax Inc VACCINE COMPOSITION FOR THE TREATMENT OF HELICOBACTER INFECTION.

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