RU93050124A - NEW DERIVATIVES OF ERYTHROMYCIN, THE METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS - Google Patents

NEW DERIVATIVES OF ERYTHROMYCIN, THE METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS

Info

Publication number
RU93050124A
RU93050124A RU93050124/04A RU93050124A RU93050124A RU 93050124 A RU93050124 A RU 93050124A RU 93050124/04 A RU93050124/04 A RU 93050124/04A RU 93050124 A RU93050124 A RU 93050124A RU 93050124 A RU93050124 A RU 93050124A
Authority
RU
Russia
Prior art keywords
erythromycin
pharmaceutical composition
basis
production
new derivatives
Prior art date
Application number
RU93050124/04A
Other languages
Russian (ru)
Other versions
RU2114859C1 (en
Inventor
Агурида Константин
Боннефой Ален
Шанто Жан-Франсуа
Дени Олексис
Ле Мартрэ Одиль
Original Assignee
Руссель-Юклаф
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9213321A external-priority patent/FR2697524B1/en
Application filed by Руссель-Юклаф filed Critical Руссель-Юклаф
Publication of RU93050124A publication Critical patent/RU93050124A/en
Application granted granted Critical
Publication of RU2114859C1 publication Critical patent/RU2114859C1/en

Links

Claims (1)

Изобретение касается новых производных эритромицина, обладающих антибиотической активностью в отношении грамположительных бактерий, к способу получения новых соединений и к фармацевтической композиции на их основе.The invention relates to new derivatives of erythromycin with antibiotic activity against gram-positive bacteria, to a method for producing new compounds and to a pharmaceutical composition based on them.
RU93050124A 1992-11-05 1993-11-04 Erythromycin derivatives, pharmaceutical composition, method of synthesis of erythromycin derivatives RU2114859C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9213321A FR2697524B1 (en) 1992-11-05 1992-11-05 New erythromycin derivatives, their preparation process and their use as drugs.
FR9213321 1992-11-05

Publications (2)

Publication Number Publication Date
RU93050124A true RU93050124A (en) 1997-02-20
RU2114859C1 RU2114859C1 (en) 1998-07-10

Family

ID=9435255

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93050124A RU2114859C1 (en) 1992-11-05 1993-11-04 Erythromycin derivatives, pharmaceutical composition, method of synthesis of erythromycin derivatives

Country Status (15)

Country Link
US (1) US5543400A (en)
EP (1) EP0606024B1 (en)
JP (1) JP3334980B2 (en)
KR (1) KR100319358B1 (en)
CN (1) CN1033273C (en)
AT (1) ATE135709T1 (en)
AU (1) AU664122B2 (en)
CA (1) CA2102454C (en)
DE (1) DE69301907T2 (en)
DK (1) DK0606024T3 (en)
ES (1) ES2085129T3 (en)
FR (1) FR2697524B1 (en)
GR (1) GR3019384T3 (en)
HU (1) HU217977B (en)
RU (1) RU2114859C1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
FR2718450B1 (en) * 1994-04-08 1997-01-10 Roussel Uclaf New erythromycin derivatives, their preparation process and their use as drugs.
FR2719587B1 (en) * 1994-05-03 1996-07-12 Roussel Uclaf New erythromycin derivatives, their preparation process and their use as drugs.
FR2727969B1 (en) * 1994-12-09 1997-01-17 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR2732023B1 (en) * 1995-03-22 1997-04-30 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR2732684B1 (en) * 1995-04-06 1997-04-30 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
US5747466A (en) * 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
FR2751656B1 (en) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
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UA51730C2 (en) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-0-substituted ketolides having antibacterial activity
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
US5780604A (en) * 1997-09-26 1998-07-14 Abbott Laboratories 11,12-cyclic phosphite or phosphate derivatives of erythromycin and related macrolides
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
FR2781484B1 (en) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc NOVEL 6-DEOXY ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR2785612A1 (en) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc NOVEL DERIVATIVES OF ERYTHROMYCIN, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS
AU5995299A (en) * 1998-11-03 2000-05-22 Pfizer Products Inc. Novel macrolide antibiotics
ID30233A (en) 1999-01-27 2001-11-15 Pfizer Prod Inc ANTIBIOTICS OF TETOLIDA
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
HUP0201516A3 (en) * 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
US7091196B2 (en) * 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
JP2006523229A (en) * 2003-03-05 2006-10-12 リブ−エックス ファーマシューティカルズ，インコーポレイテッド Bifunctional heterocyclic compounds and methods for their production and use
EP1638549A4 (en) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc Novel antibacterial agents
WO2005007143A2 (en) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Use of makrolides and ketolides for the treatment of tuberculosis
US20070149463A1 (en) * 2003-10-30 2007-06-28 Oyelere Adegboyega K Bifunctional macrolide heterocyclic compounds and methods of making and using the same
EP1699808A1 (en) * 2003-11-18 2006-09-13 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
AU2005317735B2 (en) * 2004-12-21 2009-06-04 Pfizer Products Inc. Macrolides
CA2589019A1 (en) * 2005-01-12 2006-07-20 Alpharma Aps Erythromycin derivatives as antibacterial agents
EP2214484A4 (en) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc Process for the preparation of macrolide antibacterial agents
US8796232B2 (en) * 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN103080122A (en) 2010-03-22 2013-05-01 森普拉制药公司 Crystalline forms of a macrolide, and uses therefor
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (en) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド Hydrogen bond forming fluoroketolides for disease treatment
CN104470527B (en) 2012-03-27 2019-05-28 森普拉制药公司 For applying the parenteral administration of macrolide antibiotic
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

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DE2936865A1 (en) * 1979-09-12 1981-04-02 Bayer Ag, 5090 Leverkusen Animal growth promotion with picromycin derivs. - comprising 10,11-di:hydro- and 2'-acetyl-picromycin
US5175150A (en) * 1985-08-31 1992-12-29 Kitasato, Kenkyusho Erythromycin derivative
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
KR0166096B1 (en) * 1990-11-28 1999-01-15 우에하라 아키라 6-o-methylerythromycin-a derivative

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