RU2644677C2 - Мсн-специфичные пептиды со смещенной рамкой считывания (псрс) для предотвращения и лечения рака - Google Patents

Мсн-специфичные пептиды со смещенной рамкой считывания (псрс) для предотвращения и лечения рака Download PDF

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RU2644677C2
RU2644677C2 RU2015115785A RU2015115785A RU2644677C2 RU 2644677 C2 RU2644677 C2 RU 2644677C2 RU 2015115785 A RU2015115785 A RU 2015115785A RU 2015115785 A RU2015115785 A RU 2015115785A RU 2644677 C2 RU2644677 C2 RU 2644677C2
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vaccine according
peptide
mch
cancer
vaccine
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RU2015115785A
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Russian (ru)
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RU2015115785A (ru
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Маттиас КЛООР
Мириам РОЙШЕНБАХ
КНЕБЕЛЬ-ДЁБЕРИЦ Магнус ФОН
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Рупрехт-Карлс-Университэт Гейдельберг
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2015115785A 2012-12-13 2012-12-13 Мсн-специфичные пептиды со смещенной рамкой считывания (псрс) для предотвращения и лечения рака RU2644677C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/005154 WO2014090265A1 (en) 2012-12-13 2012-12-13 Msi-specific frameshift peptides (fsp) for prevention and treatment of cancer

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RU2015115785A RU2015115785A (ru) 2017-01-16
RU2644677C2 true RU2644677C2 (ru) 2018-02-13

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RU2015115785A RU2644677C2 (ru) 2012-12-13 2012-12-13 Мсн-специфичные пептиды со смещенной рамкой считывания (псрс) для предотвращения и лечения рака

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KR (1) KR101810840B1 (ko)
CN (1) CN104853764B (ko)
BR (1) BR112015013737B1 (ko)
RU (1) RU2644677C2 (ko)
WO (1) WO2014090265A1 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018223093A1 (en) * 2017-06-02 2018-12-06 Arizona Board Of Regents On Behalf Of Arizona State University Universal cancer vaccines and methods of making and using same
AU2018298849B2 (en) * 2017-07-12 2022-07-14 Nouscom Ag A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (MSI) cancers
US12025615B2 (en) 2017-09-15 2024-07-02 Arizona Board Of Regents On Behalf Of Arizona State University Methods of classifying response to immunotherapy for cancer
EP4038222A4 (en) 2019-10-02 2023-10-18 Arizona Board of Regents on behalf of Arizona State University METHODS AND COMPOSITIONS FOR IDENTIFYING NEOANTIGENS FOR USE IN THE TREATMENT AND PREVENTION OF CANCER
CN115916251A (zh) 2020-05-28 2023-04-04 休博治疗有限公司 肽混合物
EP4052716A1 (en) 2021-03-04 2022-09-07 Deutsches Krebsforschungszentrum - Stiftung des öffentlichen Rechts / Universität Heidelberg Cancer therapy involving car-engineered t-cells and parvovirus h-1

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003087162A2 (en) * 2002-04-18 2003-10-23 Mtm Laboratories Ag Neopeptides and methods useful for detection and treatment of cancer
RU2424247C2 (ru) * 2005-11-30 2011-07-20 Интернэшнл Инститьют Оф Кэнсер Иммьюнолоджи, Инк. Пептид, индуцирующий цитотоксические т-клетки (цтл), способ индукции цтл, антитело, связывающееся с этим пептидом, применение пептида в фармацевтической композиции и для лечения или предупреждения рака, антигенпредставляющая клетка

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69535036T3 (de) 1994-07-15 2011-07-07 The University of Iowa Research Foundation, IA Immunomodulatorische oligonukleotide
ES2548391T3 (es) * 2011-09-21 2015-10-16 Ruprecht-Karls-Universität Heidelberg Péptidos de cambio de marco (FSP) específicos de MSI para prevención y tratamiento del cáncer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003087162A2 (en) * 2002-04-18 2003-10-23 Mtm Laboratories Ag Neopeptides and methods useful for detection and treatment of cancer
RU2424247C2 (ru) * 2005-11-30 2011-07-20 Интернэшнл Инститьют Оф Кэнсер Иммьюнолоджи, Инк. Пептид, индуцирующий цитотоксические т-клетки (цтл), способ индукции цтл, антитело, связывающееся с этим пептидом, применение пептида в фармацевтической композиции и для лечения или предупреждения рака, антигенпредставляющая клетка

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
LINNEBACHER M., Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens, Int. J. Cancer, 2001,v.93, p.6-11. *
LINNEBACHER M., Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens, Int. J. Cancer, 2001,v.93, p.6-11. SCHWITALLE Y., Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells, Cancer Immunity, 2004, v.4, p.14. SCHWITALLE Y., Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers, Gastroenterology, 2008, v.134. *
SCHWITALLE Y., Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers, Gastroenterology, 2008, v.134. *
SCHWITALLE Y., Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells, Cancer Immunity, 2004, v.4, p.14. *

Also Published As

Publication number Publication date
KR20150084060A (ko) 2015-07-21
WO2014090265A1 (en) 2014-06-19
KR101810840B1 (ko) 2017-12-20
CN104853764B (zh) 2018-06-22
BR112015013737B1 (pt) 2021-07-27
BR112015013737A2 (pt) 2017-07-11
CN104853764A (zh) 2015-08-19
RU2015115785A (ru) 2017-01-16

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