RU2644677C2 - Мсн-специфичные пептиды со смещенной рамкой считывания (псрс) для предотвращения и лечения рака - Google Patents
Мсн-специфичные пептиды со смещенной рамкой считывания (псрс) для предотвращения и лечения рака Download PDFInfo
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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PCT/EP2012/005154 WO2014090265A1 (en) | 2012-12-13 | 2012-12-13 | Msi-specific frameshift peptides (fsp) for prevention and treatment of cancer |
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KR (1) | KR101810840B1 (ko) |
CN (1) | CN104853764B (ko) |
BR (1) | BR112015013737B1 (ko) |
RU (1) | RU2644677C2 (ko) |
WO (1) | WO2014090265A1 (ko) |
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WO2018223093A1 (en) * | 2017-06-02 | 2018-12-06 | Arizona Board Of Regents On Behalf Of Arizona State University | Universal cancer vaccines and methods of making and using same |
AU2018298849B2 (en) * | 2017-07-12 | 2022-07-14 | Nouscom Ag | A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (MSI) cancers |
US12025615B2 (en) | 2017-09-15 | 2024-07-02 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods of classifying response to immunotherapy for cancer |
EP4038222A4 (en) | 2019-10-02 | 2023-10-18 | Arizona Board of Regents on behalf of Arizona State University | METHODS AND COMPOSITIONS FOR IDENTIFYING NEOANTIGENS FOR USE IN THE TREATMENT AND PREVENTION OF CANCER |
CN115916251A (zh) | 2020-05-28 | 2023-04-04 | 休博治疗有限公司 | 肽混合物 |
EP4052716A1 (en) | 2021-03-04 | 2022-09-07 | Deutsches Krebsforschungszentrum - Stiftung des öffentlichen Rechts / Universität Heidelberg | Cancer therapy involving car-engineered t-cells and parvovirus h-1 |
Citations (2)
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WO2003087162A2 (en) * | 2002-04-18 | 2003-10-23 | Mtm Laboratories Ag | Neopeptides and methods useful for detection and treatment of cancer |
RU2424247C2 (ru) * | 2005-11-30 | 2011-07-20 | Интернэшнл Инститьют Оф Кэнсер Иммьюнолоджи, Инк. | Пептид, индуцирующий цитотоксические т-клетки (цтл), способ индукции цтл, антитело, связывающееся с этим пептидом, применение пептида в фармацевтической композиции и для лечения или предупреждения рака, антигенпредставляющая клетка |
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DE69535036T3 (de) | 1994-07-15 | 2011-07-07 | The University of Iowa Research Foundation, IA | Immunomodulatorische oligonukleotide |
ES2548391T3 (es) * | 2011-09-21 | 2015-10-16 | Ruprecht-Karls-Universität Heidelberg | Péptidos de cambio de marco (FSP) específicos de MSI para prevención y tratamiento del cáncer |
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WO2003087162A2 (en) * | 2002-04-18 | 2003-10-23 | Mtm Laboratories Ag | Neopeptides and methods useful for detection and treatment of cancer |
RU2424247C2 (ru) * | 2005-11-30 | 2011-07-20 | Интернэшнл Инститьют Оф Кэнсер Иммьюнолоджи, Инк. | Пептид, индуцирующий цитотоксические т-клетки (цтл), способ индукции цтл, антитело, связывающееся с этим пептидом, применение пептида в фармацевтической композиции и для лечения или предупреждения рака, антигенпредставляющая клетка |
Non-Patent Citations (4)
Title |
---|
LINNEBACHER M., Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens, Int. J. Cancer, 2001,v.93, p.6-11. * |
LINNEBACHER M., Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens, Int. J. Cancer, 2001,v.93, p.6-11. SCHWITALLE Y., Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells, Cancer Immunity, 2004, v.4, p.14. SCHWITALLE Y., Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers, Gastroenterology, 2008, v.134. * |
SCHWITALLE Y., Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers, Gastroenterology, 2008, v.134. * |
SCHWITALLE Y., Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells, Cancer Immunity, 2004, v.4, p.14. * |
Also Published As
Publication number | Publication date |
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KR20150084060A (ko) | 2015-07-21 |
WO2014090265A1 (en) | 2014-06-19 |
KR101810840B1 (ko) | 2017-12-20 |
CN104853764B (zh) | 2018-06-22 |
BR112015013737B1 (pt) | 2021-07-27 |
BR112015013737A2 (pt) | 2017-07-11 |
CN104853764A (zh) | 2015-08-19 |
RU2015115785A (ru) | 2017-01-16 |
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