RU2017133521A - Половолоконное мембранное устройство очистки крови - Google Patents
Половолоконное мембранное устройство очистки крови Download PDFInfo
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- RU2017133521A RU2017133521A RU2017133521A RU2017133521A RU2017133521A RU 2017133521 A RU2017133521 A RU 2017133521A RU 2017133521 A RU2017133521 A RU 2017133521A RU 2017133521 A RU2017133521 A RU 2017133521A RU 2017133521 A RU2017133521 A RU 2017133521A
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- Russia
- Prior art keywords
- cylindrical container
- head
- hollow fiber
- fiber membrane
- face
- Prior art date
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- 239000012528 membrane Substances 0.000 title claims 13
- 239000008280 blood Substances 0.000 title claims 2
- 210000004369 blood Anatomy 0.000 title claims 2
- 238000004140 cleaning Methods 0.000 title 1
- 239000000835 fiber Substances 0.000 title 1
- 239000012510 hollow fiber Substances 0.000 claims 12
- 239000011347 resin Substances 0.000 claims 10
- 229920005989 resin Polymers 0.000 claims 10
- 238000005266 casting Methods 0.000 claims 8
- 239000012530 fluid Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000004743 Polypropylene Substances 0.000 claims 1
- 230000006835 compression Effects 0.000 claims 1
- 238000007906 compression Methods 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- -1 polypropylene Polymers 0.000 claims 1
- 229920001155 polypropylene Polymers 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 238000003466 welding Methods 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
- A61M1/1625—Dialyser of the outside perfusion type, i.e. blood flow outside hollow membrane fibres or tubes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1652—Holding or locking systems for the membrane unit
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
- A61M1/3635—Constructional details
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- B01D61/24—Dialysis ; Membrane extraction
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- B29C66/12469—Tongue and groove joints characterised by the female part, i.e. the part comprising the groove being asymmetric
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- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
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- B29C66/20—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines
- B29C66/21—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being formed by a single dot or dash or by several dots or dashes, i.e. spot joining or spot welding
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
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- B29C66/01—General aspects dealing with the joint area or with the area to be joined
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B29C66/00—General aspects of processes or apparatus for joining preformed parts
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- B29C66/302—Particular design of joint configurations the area to be joined comprising melt initiators
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- B29C66/30223—Particular design of joint configurations the area to be joined comprising melt initiators said melt initiators being integral with at least one of the parts to be joined said melt initiators being rib-like
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- B29C66/53—Joining single elements to tubular articles, hollow articles or bars
- B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
- B29C66/5344—Joining single elements to open ends of tubular or hollow articles or to the ends of bars said single elements being substantially annular, i.e. of finite length, e.g. joining flanges to tube ends
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
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- B29C66/739—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset
- B29C66/7392—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic
- B29C66/73921—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic characterised by the materials of both parts being thermoplastics
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
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Claims (17)
1. Половолоконное мембранное устройство очистки крови, содержащее
цилиндрический контейнер, имеющий один открытый конец и другой открытый конец;
пучок половолоконных мембран, упакованных в цилиндрический контейнер;
фиксирующую часть из заливочной смолы, в которую заделывают пучок половолоконных мембран, и которая фиксирует его на каждом конце цилиндрического контейнера;
головку, обеспеченную на каждом конце цилиндрического контейнера и имеющую патрубок, служащий в качестве выпуска или впуска текучего вещества; и
порт, обеспеченный сбоку цилиндрического контейнера и служащий в качестве выпуска или впуска текучего вещества, проходящего через половолоконную мембрану,
причем нахлесточное соединение используют в качестве конструкции соединения для сварки,
при этом устройство имеет структуру, в которой головку и цилиндрический контейнер сваривают в, по меньшей мере, двух или более участках,
причем внутренняя поверхность головки находится в контакте со срезанной гранью фиксирующей части из заливочной смолы, которую формируют посредством срезания части внешней стороны фиксирующей части из заливочной смолы в направлении длины цилиндрического контейнера, а не торцевой гранью каждого конца цилиндрического контейнера, причем срезанная грань фиксирующей части из заливочной смолы находится в компрессионно деформированном состоянии.
2. Половолоконное мембранное устройство по п. 1, в котором сваренная область содержит непрерывную или прерывистую область по периметру на боковой грани на внешней периферии цилиндрического контейнера и на внутренней поверхности головки и непрерывную или прерывистую область по периметру на каждой торцевой или боковой грани конца цилиндрического контейнера и на внутренней поверхности головки.
3. Половолоконное мембранное устройство по п. 1 или 2, в котором контактная поверхность на внутренней поверхности головки в контакте со срезанной гранью фиксирующей части из заливочной смолы имеет плоскую грань, проходящую наружу от внутреннего периферического края вдоль грани по существу параллельно срезанной грани фиксирующей части из заливочной смолы.
4. Половолоконное мембранное устройство по любому из пп. 1 - 3, в котором, в продольном сечении, где сваривают головку и цилиндрический контейнер, общая сумма площади поперечного сечения, где сваривают внутреннюю поверхность головки и цилиндрический контейнер, составляет от 0,05 до 1,25 мм2.
5. Половолоконное мембранное устройство по любому из пп. 1 - 4, в котором, в продольном сечении, где сваривают головку и цилиндрический контейнер, ширина контакта между срезанной гранью фиксирующей части из заливочной смолы и внутренней поверхностью головки составляет от 0,3 мм до 1,5 мм.
6. Половолоконное мембранное устройство по любому из пп. 1 - 5, в котором, в продольном сечении, где сваривают головку и цилиндрический контейнер, высота от торцевой грани цилиндрического контейнера до срезанной грани фиксирующей части из заливочной смолы находится в диапазоне от 0,1 мм до 1,5 мм.
7. Половолоконное мембранное устройство по любому из пп. 1 - 6, в котором сырье цилиндрического контейнера и головок представляет собой полипропиленовую смолу.
8. Половолоконное мембранное устройство по любому из пп. 1 - 7, в котором заливочная смола имеет твердость, определяемую с помощью дюрометра Шора типа D от 30 до 70.
9. Половолоконное мембранное устройство по любому из пп. 1 - 8, в котором, в продольном сечении головки и цилиндрического контейнера, одно из головки и цилиндрического контейнера имеет выпуклую часть выпуклой формы, другое имеет вогнутую часть вогнутой формы, на которую сажают выпуклую часть выпуклой формы, выпуклая часть имеет ширину ведущей торцевой грани больше ширины нижней грани вогнутой части, и по меньшей мере одна боковая грань внутренних граней вогнутой части имеет конструкцию нахлесточного соединения со скосом, который делает ширину вогнутой части нижней грани меньше ширины верхней грани вогнутой части.
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JP2015-077175 | 2015-04-03 | ||
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PCT/JP2016/060973 WO2016159375A1 (ja) | 2015-04-03 | 2016-04-01 | 中空糸膜型血液浄化器 |
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US20190105608A1 (en) * | 2016-03-31 | 2019-04-11 | Asahi Kasei Medical Co., Ltd. | Hollow fiber membrane module and manufacturing method therefor |
US20190337236A1 (en) * | 2018-05-02 | 2019-11-07 | Zhuhai Ding Rong Plastic Products Co., Ltd | Plastic Containing Assembly Having Filler Material Arrangement for Welding |
JP7221780B2 (ja) * | 2019-04-26 | 2023-02-14 | 旭化成メディカル株式会社 | 中空糸膜モジュールとその製造方法 |
CN113546231B (zh) * | 2021-06-11 | 2023-08-15 | 中聚科技股份有限公司 | 一种高耐久的超声结构焊接及血液净化器 |
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US3882024A (en) * | 1974-04-19 | 1975-05-06 | Dow Chemical Co | Header for stagnation-sensitive liquids |
US4031012A (en) * | 1975-09-17 | 1977-06-21 | Gics Pharmaceuticals, Inc. | Separatory apparatus |
JPS52132597A (en) * | 1976-04-30 | 1977-11-07 | Nippon Zeon Co | Hollow yarn type material moving device |
AU2200783A (en) * | 1982-12-20 | 1984-07-17 | Baxter Travenol Laboratories Inc. | End closure for tubular housing |
JPS61240964A (ja) * | 1985-04-18 | 1986-10-27 | 帝人株式会社 | 体液処理器及びその製造方法 |
JPH04305229A (ja) * | 1991-04-02 | 1992-10-28 | Terumo Corp | 中空糸型物質移動装置 |
JP2000025689A (ja) * | 1998-07-16 | 2000-01-25 | Mitsubishi Heavy Ind Ltd | カプラーソケットの取り付け方法 |
JP4509370B2 (ja) * | 2000-12-26 | 2010-07-21 | ナイルス株式会社 | 樹脂構造体の密閉結合構造 |
JP4421827B2 (ja) * | 2003-02-27 | 2010-02-24 | 川澄化学工業株式会社 | 体液処理装置 |
JP5023430B2 (ja) * | 2004-03-17 | 2012-09-12 | 東レ株式会社 | 中空糸膜モジュールおよびその製造方法 |
JP2007175566A (ja) * | 2005-12-27 | 2007-07-12 | Toray Ind Inc | 中空糸膜モジュール |
JP2009240499A (ja) * | 2008-03-31 | 2009-10-22 | Asahi Kasei Kuraray Medical Co Ltd | 血液透析濾過モジュール |
JP5330127B2 (ja) * | 2009-07-08 | 2013-10-30 | ハジメ産業株式会社 | 樹脂成形体の接合構造 |
CN102770169B (zh) * | 2010-02-22 | 2015-08-26 | 旭化成医疗株式会社 | 医疗用具及中空纤维膜型医疗用具 |
JP6231733B2 (ja) * | 2011-05-23 | 2017-11-15 | 旭化成メディカル株式会社 | 中空糸膜型医療用具 |
JP5355744B2 (ja) * | 2011-05-30 | 2013-11-27 | 日機装株式会社 | 中空糸型フィルタ |
EP2719408A4 (en) * | 2011-06-09 | 2014-12-03 | Asahi Kasei Medical Co Ltd | HOLLOW FIBER MEMBRANE FOR BLOOD TREATMENT AND HOLLOW FIBER MEMBRANE-TYPE BLOOD TREATMENT APPARATUS |
JP6028730B2 (ja) * | 2012-03-28 | 2016-11-16 | 東レ株式会社 | 中空糸膜モジュール |
CN104394966B (zh) * | 2012-07-05 | 2017-03-01 | 东丽株式会社 | 中空丝膜模组 |
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TW201637671A (zh) | 2016-11-01 |
JPWO2016159375A1 (ja) | 2017-12-21 |
EP3278821A4 (en) | 2018-04-04 |
WO2016159375A1 (ja) | 2016-10-06 |
CN107427623A (zh) | 2017-12-01 |
CA2978694A1 (en) | 2016-10-06 |
EP3278821A1 (en) | 2018-02-07 |
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