RU2017104518A - Композиция для предупреждения или лечения ожирения, содержащая α-липоевую кислоту и N-ацетилцистеин в качестве активных ингредиентов - Google Patents
Композиция для предупреждения или лечения ожирения, содержащая α-липоевую кислоту и N-ацетилцистеин в качестве активных ингредиентов Download PDFInfo
- Publication number
- RU2017104518A RU2017104518A RU2017104518A RU2017104518A RU2017104518A RU 2017104518 A RU2017104518 A RU 2017104518A RU 2017104518 A RU2017104518 A RU 2017104518A RU 2017104518 A RU2017104518 A RU 2017104518A RU 2017104518 A RU2017104518 A RU 2017104518A
- Authority
- RU
- Russia
- Prior art keywords
- lipoic acid
- composition
- acetylcysteine
- active ingredients
- prevention
- Prior art date
Links
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 title claims 7
- 208000008589 Obesity Diseases 0.000 title claims 7
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 title claims 7
- 235000019136 lipoic acid Nutrition 0.000 title claims 7
- 235000020824 obesity Nutrition 0.000 title claims 7
- 229960002663 thioctic acid Drugs 0.000 title claims 7
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title claims 4
- 229960004308 acetylcysteine Drugs 0.000 title claims 4
- 239000004480 active ingredient Substances 0.000 title claims 4
- 230000002265 prevention Effects 0.000 title claims 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Child & Adolescent Psychology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pediatric Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Non-Alcoholic Beverages (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Claims (7)
1. Композиция для предупреждения или лечения ожирения, содержащая α-липоевую кислоту и N-ацетилцистеин в качестве активных ингредиентов.
2. Композиция для предупреждения или лечения ожирения по п. 1, где α-липоевая кислота представляет собой рацемат или R-изомер.
3. Пищевая композиция для предупреждения или уменьшения ожирения, содержащая α-липоевую кислоту и N-ацетилцистеин в качестве активных ингредиентов.
4. Пищевая композиция для предупреждения или уменьшения ожирения по п. 3, где α-липоевая кислота представляет собой рацемат или R-изомер.
5. Способ предупреждения или лечения ожирения, включающий:
введение субъекту эффективного количества композиции, содержащей α-липоевую кислоту и N-ацетилцистеин в качестве активных ингредиентов.
6. Способ предупреждения или лечения ожирения по п. 5, где α-липоевая кислота представляет собой рацемат или R-изомер.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/KR2015/010783 WO2017065328A1 (ko) | 2015-10-13 | 2015-10-13 | 알파-리포익산 및 n-아세틸시스테인을 유효성분으로 포함하는 비만의 예방 또는 치료용 조성물 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| RU2017104518A3 RU2017104518A3 (ru) | 2018-08-17 |
| RU2017104518A true RU2017104518A (ru) | 2018-08-17 |
| RU2670612C2 RU2670612C2 (ru) | 2018-10-24 |
| RU2670612C9 RU2670612C9 (ru) | 2018-11-23 |
Family
ID=58462074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017104518A RU2670612C9 (ru) | 2015-10-13 | 2015-10-13 | Композиция для предупреждения или лечения ожирения, содержащая α-липоевую кислоту и N-ацетилцистеин в качестве активных ингредиентов |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20170239214A1 (ru) |
| EP (1) | EP3366292B1 (ru) |
| JP (1) | JP2018531879A (ru) |
| CN (1) | CN107106540A (ru) |
| AU (1) | AU2015405046B2 (ru) |
| BR (2) | BR112017002911A2 (ru) |
| CA (1) | CA2957711A1 (ru) |
| GB (1) | GB2548476A (ru) |
| RU (1) | RU2670612C9 (ru) |
| WO (1) | WO2017065328A1 (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107382987A (zh) * | 2017-07-19 | 2017-11-24 | 佛山市第五人民医院 | 一种具有预防和治疗创伤性脑损伤活性的化合物及其制备方法和用途 |
| WO2021126227A1 (en) | 2019-12-20 | 2021-06-24 | Vector Vitale Ip Llc | Composition and method for the prevention and treatment of obesity |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100427637B1 (ko) * | 2001-06-05 | 2004-04-27 | 이인규 | 세포내 에너지 소비 증가제 |
| KR100547415B1 (ko) | 2001-10-09 | 2006-01-31 | 엘지전자 주식회사 | 진공청소기용 집진통 |
| US6733793B2 (en) * | 2002-06-04 | 2004-05-11 | Metaproteomics, Llc | Oral composition with insulin-like activities and methods of use |
| KR100524289B1 (ko) * | 2003-05-03 | 2005-10-27 | 이인규 | 엔-아세틸시스테인을 유효성분으로 함유하는 비만 억제용조성물 |
| US7399755B2 (en) * | 2005-02-17 | 2008-07-15 | Premier Micronutrient Corporation | Formulations comprising multiple dietary and endogenously made antioxidants and B-vitamins and use of same |
| KR20090075269A (ko) * | 2008-01-03 | 2009-07-08 | 전북대학교산학협력단 | 비만 예방 및 치료용 조성물 |
| UA37459U (ru) * | 2008-07-02 | 2008-11-25 | Інститут Біохімії Ім. О.В. Палладіна Національної Академії Наук України | Комплексная пищевая добавка для оздоровительного похудения |
| US8362080B2 (en) * | 2008-12-18 | 2013-01-29 | Baylor College Of Medicine | Increasing glutathione levels for therapy |
| ES2626651T3 (es) * | 2011-06-24 | 2017-07-25 | K-Pax Pharmaceuticals, Inc. | Composiciones para el tratamiento de la fatiga crónica |
| US20140045874A1 (en) * | 2012-07-09 | 2014-02-13 | Noglo Llc | Prevention of alcohol reaction with dietary supplements |
| US20140243400A1 (en) * | 2013-02-28 | 2014-08-28 | University of Alaska Anchorage | Compositions comprising citric acid and malic acid and methods and uses thereof |
-
2015
- 2015-10-13 AU AU2015405046A patent/AU2015405046B2/en not_active Ceased
- 2015-10-13 WO PCT/KR2015/010783 patent/WO2017065328A1/ko active Application Filing
- 2015-10-13 GB GB1702336.7A patent/GB2548476A/en not_active Withdrawn
- 2015-10-13 US US15/503,968 patent/US20170239214A1/en not_active Abandoned
- 2015-10-13 RU RU2017104518A patent/RU2670612C9/ru not_active IP Right Cessation
- 2015-10-13 CN CN201580043567.XA patent/CN107106540A/zh active Pending
- 2015-10-13 BR BR112017002911A patent/BR112017002911A2/pt not_active Application Discontinuation
- 2015-10-13 BR BR112017002805-0A patent/BR112017002805A2/pt not_active Application Discontinuation
- 2015-10-13 JP JP2017507981A patent/JP2018531879A/ja active Pending
- 2015-10-13 EP EP15900611.3A patent/EP3366292B1/en active Active
- 2015-10-13 CA CA2957711A patent/CA2957711A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN107106540A (zh) | 2017-08-29 |
| WO2017065328A1 (ko) | 2017-04-20 |
| RU2017104518A3 (ru) | 2018-08-17 |
| EP3366292A4 (en) | 2019-05-08 |
| CA2957711A1 (en) | 2017-04-13 |
| BR112017002911A2 (pt) | 2017-12-12 |
| AU2015405046B2 (en) | 2018-02-22 |
| US20170239214A1 (en) | 2017-08-24 |
| BR112017002805A2 (pt) | 2018-04-17 |
| JP2018531879A (ja) | 2018-11-01 |
| EP3366292A1 (en) | 2018-08-29 |
| RU2670612C2 (ru) | 2018-10-24 |
| RU2670612C9 (ru) | 2018-11-23 |
| EP3366292B1 (en) | 2020-12-02 |
| GB2548476A (en) | 2017-09-20 |
| GB201702336D0 (en) | 2017-03-29 |
| AU2015405046A1 (en) | 2017-04-27 |
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Effective date: 20201014 |