RU2016125141A - Композиции, содержащие плёнку, для использования в ротовой полости - Google Patents
Композиции, содержащие плёнку, для использования в ротовой полости Download PDFInfo
- Publication number
- RU2016125141A RU2016125141A RU2016125141A RU2016125141A RU2016125141A RU 2016125141 A RU2016125141 A RU 2016125141A RU 2016125141 A RU2016125141 A RU 2016125141A RU 2016125141 A RU2016125141 A RU 2016125141A RU 2016125141 A RU2016125141 A RU 2016125141A
- Authority
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- Prior art keywords
- composition according
- film
- dye
- gel
- cellulose
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims 14
- 210000000214 mouth Anatomy 0.000 title 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 230000001680 brushing effect Effects 0.000 claims 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 3
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims 2
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 229960003237 betaine Drugs 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 238000004140 cleaning Methods 0.000 claims 2
- 239000003086 colorant Substances 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical group CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 claims 1
- RPZANUYHRMRTTE-UHFFFAOYSA-N 2,3,4-trimethoxy-6-(methoxymethyl)-5-[3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane;1-[[3,4,5-tris(2-hydroxybutoxy)-6-[4,5,6-tris(2-hydroxybutoxy)-2-(2-hydroxybutoxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]butan-2-ol Chemical compound COC1C(OC)C(OC)C(COC)OC1OC1C(OC)C(OC)C(OC)OC1COC.CCC(O)COC1C(OCC(O)CC)C(OCC(O)CC)C(COCC(O)CC)OC1OC1C(OCC(O)CC)C(OCC(O)CC)C(OCC(O)CC)OC1COCC(O)CC RPZANUYHRMRTTE-UHFFFAOYSA-N 0.000 claims 1
- SGHZXLIDFTYFHQ-UHFFFAOYSA-L Brilliant Blue Chemical compound [Na+].[Na+].C=1C=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C(=CC=CC=2)S([O-])(=O)=O)C=CC=1N(CC)CC1=CC=CC(S([O-])(=O)=O)=C1 SGHZXLIDFTYFHQ-UHFFFAOYSA-L 0.000 claims 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 1
- 239000000551 dentifrice Substances 0.000 claims 1
- 229910003460 diamond Inorganic materials 0.000 claims 1
- 239000010432 diamond Substances 0.000 claims 1
- -1 hydroxyethyl propyl Chemical group 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 239000002985 plastic film Substances 0.000 claims 1
- 229920006255 plastic film Polymers 0.000 claims 1
- 239000004014 plasticizer Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 238000005201 scrubbing Methods 0.000 claims 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims 1
- 239000000377 silicon dioxide Substances 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0254—Platelets; Flakes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
Claims (19)
1. Композиция для гигиены ротовой полости, содержащая:
(i) клочки водорастворимой или растворимой пленки, состоящей из
(a) водорастворимого полимера целлюлозы в виде полимерной матрицы и
(b) материала силикатный золь-гель/краситель, внедренного в полимерную матрицу, и
(ii) орально приемлемый носитель,
причем клочки пленки пластичны.
2. Композиция по п. 1, отличающаяся тем, что целлюлозный полимер выбирают из метилцеллюлозы, гидроксипропилметилцеллюлозы, гидроксиэтилпропилцеллюлозы, гидроксибутилметилцеллюлозы, карбоксиметилцеллюлозы и их смесей.
3. Композиция по п. 1 отличающаяся тем, что целлюлозный полимер представляет собой гидроксипропилметилцеллюлозу.
4. Композиция по п. 1, отличающаяся тем, что пленка дополнительно содержит пластификатор, выбранный из сорбитола, пропиленгликоля, глицерина и низкомолекулярного полиэтиленгликоля.
5. Композиция по п. 1, отличающаяся тем, что пленка содержит бетаин.
6. Композиция по п. 1, отличающаяся тем, что пленка, по существу, растворена после периода более чем 30 и менее чем 180 с чистки зубной щеткой, чистки скребком или перемешивания в присутствии воды.
7. Композиция по п. 1, отличающаяся тем, что средняя толщина пленки составляет 0,038-0,076 мм (1,5-3 мил).
8. Композиция по п. 1, отличающаяся тем, что краситель представляет собой бриллиантовый синий №1.
9. Композиция по п. 1, содержащая, по сухой массе пленки, 20-60% гидроксипропилметилцеллюлозы; 10-30% пропиленгликоля; 1-5% бетаина; и 15-30% материала силикатный золь-гель/краситель.
10. Композиция по п. 1, которая стабильна при хранении при приблизительно комнатной температуре в течение 1, 2, 3, 6 месяцев, 1 г или 2 лет.
11. Композиция по п. 1, которая представляет собой прозрачную гелевую зубную пасту;
отличающаяся тем, что краситель выпускается из упомянутой первой пленки после чистки в течение от 30 до 120 с.
12. Способ очистки зубов, включающий чистку композицией по п. 1, при этом чистку зубной щеткой продолжают до тех пор, пока пленка не выпустит практически весь краситель, тем самым подавая пользователю цветовой сигнал об адекватном времени чистки.
13. Способ обеспечения стабильности средства для чистки зубов, содержащего краситель, который включает заключение упомянутого красителя в силикатный золь-гель и внедрение упомянутого заключенного красителя в пленку, состоящую из целлюлозного полимера, и внедрение упомянутой пленки в орально приемлемый носитель.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2013/077377 WO2015099640A1 (en) | 2013-12-23 | 2013-12-23 | Film compositions for oral use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016125141A true RU2016125141A (ru) | 2018-01-30 |
| RU2666212C2 RU2666212C2 (ru) | 2018-09-06 |
Family
ID=49956480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016125141A RU2666212C2 (ru) | 2013-12-23 | 2013-12-23 | Композиции, содержащие плёнку, для использования в ротовой полости |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10426720B2 (ru) |
| EP (1) | EP3086772A1 (ru) |
| CN (1) | CN105828802B (ru) |
| AR (1) | AR098921A1 (ru) |
| AU (1) | AU2013408898B2 (ru) |
| IL (1) | IL246301B (ru) |
| MX (1) | MX370456B (ru) |
| PH (1) | PH12016501053A1 (ru) |
| RU (1) | RU2666212C2 (ru) |
| TW (1) | TW201545767A (ru) |
| WO (1) | WO2015099640A1 (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3029103B1 (fr) * | 2014-11-27 | 2018-02-16 | Societe Industrielle Limousine D'application Biologique | Pansement adhesif soluble a base de mineraux |
| IL236099B (en) | 2014-12-07 | 2020-01-30 | Sadovsky Ltd | Odor neutralization |
| CN106999393B (zh) | 2014-12-19 | 2021-03-12 | 高露洁-棕榄公司 | 用于牙齿美白的口腔组合物 |
| DE102017127452A1 (de) * | 2017-11-21 | 2019-05-23 | Lts Lohmann Therapie-Systeme Ag | Wasserlösliche Polymerklebschichten |
| US20200308062A1 (en) * | 2019-03-28 | 2020-10-01 | Ut-Battelle, Llc | Slurry Mixtures for 3-D Slurry Extrusion of Artifacts |
| IT202200000884A1 (it) * | 2022-01-20 | 2023-07-20 | Univ Degli Studi Padova | Composizione comprendente un sol-gel di silice e una proteina serpinb3 incorporata in esso |
| WO2023139492A1 (en) * | 2022-01-20 | 2023-07-27 | Università Degli Studi Di Padova | New system for the topical pharmacological release of an active ingredient |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3662059A (en) | 1969-06-02 | 1972-05-09 | Lever Brothers Ltd | Dentifrice composition |
| US3935306A (en) * | 1972-04-11 | 1976-01-27 | Colgate-Palmolive Company | Toothpaste formulations |
| ES2042563T3 (es) | 1986-06-27 | 1993-12-16 | Lion Corp | Composicion oral. |
| US6136297A (en) | 1997-06-06 | 2000-10-24 | The Procter & Gamble Company | Delivery system for an oral care substance using a strip of material having low flexural stiffness |
| US6479036B1 (en) | 1998-06-05 | 2002-11-12 | Crosfield Limited | Particulate materials for use in dentifrice compositions |
| US6552024B1 (en) * | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
| WO2002011688A1 (en) | 2000-08-07 | 2002-02-14 | Unilever N.V. | Oral cosmetic composition comprising petroleum jelly enrobing an active agent |
| US6669229B2 (en) | 2001-03-22 | 2003-12-30 | General Motors Corporation | Automotive vehicle air bag system |
| US6585997B2 (en) * | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
| DE10143142A1 (de) | 2001-09-04 | 2003-01-30 | Bosch Gmbh Robert | Verfahren zum Betreiben einer Schaltungsanordnung, die einen Mikrocontroller und ein EEPROM enthält |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US6723304B2 (en) * | 2001-11-13 | 2004-04-20 | Noville, Inc. | Oral care compositions comprising diglycerol |
| US20030099691A1 (en) | 2001-11-16 | 2003-05-29 | Susan Lydzinski | Films containing starch |
| US6669929B1 (en) | 2002-12-30 | 2003-12-30 | Colgate Palmolive Company | Dentifrice containing functional film flakes |
| US7923030B2 (en) * | 2003-03-14 | 2011-04-12 | Sol-Gel Technologies, Inc. | Agent-encapsulating micro- and nanoparticles, methods for preparation of same and products containing same |
| EP1605908A2 (en) | 2003-03-26 | 2005-12-21 | The Procter & Gamble Company | Rapidly dissolving edible film compositions with improved film strength and stability |
| DK2105122T3 (da) | 2003-12-16 | 2013-01-14 | Colgate Palmolive Co | Sammensætninger til pleje af mund og legeme samt fremgangsmåder |
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| ATE462404T1 (de) | 2005-02-04 | 2010-04-15 | Unilever Nv | Mehrphasige zahnpastenzusammensetzung |
| US20080187497A1 (en) | 2005-02-04 | 2008-08-07 | Rupesh Kumar Agarwal | Toothpaste |
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| US9242125B2 (en) | 2005-07-21 | 2016-01-26 | Coglate-Palmolive Company | Oral composition containing non-aggregated zinc nanoparticles |
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| EP2980014B1 (en) * | 2014-07-31 | 2019-06-26 | IMEC vzw | Method for interconnected nanowire cluster formation using an Anodic Aluminium Oxide (AAO) template |
-
2013
- 2013-12-23 AU AU2013408898A patent/AU2013408898B2/en not_active Ceased
- 2013-12-23 EP EP13821365.7A patent/EP3086772A1/en not_active Withdrawn
- 2013-12-23 WO PCT/US2013/077377 patent/WO2015099640A1/en active Application Filing
- 2013-12-23 MX MX2016007835A patent/MX370456B/es active IP Right Grant
- 2013-12-23 CN CN201380081674.2A patent/CN105828802B/zh not_active Expired - Fee Related
- 2013-12-23 RU RU2016125141A patent/RU2666212C2/ru active
- 2013-12-23 US US15/107,590 patent/US10426720B2/en active Active
-
2014
- 2014-12-08 TW TW103142527A patent/TW201545767A/zh unknown
- 2014-12-22 AR ARP140104865A patent/AR098921A1/es unknown
-
2016
- 2016-06-02 PH PH12016501053A patent/PH12016501053A1/en unknown
- 2016-06-19 IL IL246301A patent/IL246301B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| MX370456B (es) | 2019-12-13 |
| TW201545767A (zh) | 2015-12-16 |
| AU2013408898B2 (en) | 2017-02-23 |
| US20160317422A1 (en) | 2016-11-03 |
| MX2016007835A (es) | 2016-09-29 |
| IL246301B (en) | 2021-01-31 |
| US10426720B2 (en) | 2019-10-01 |
| CN105828802A (zh) | 2016-08-03 |
| AU2013408898A1 (en) | 2016-06-16 |
| RU2666212C2 (ru) | 2018-09-06 |
| EP3086772A1 (en) | 2016-11-02 |
| WO2015099640A1 (en) | 2015-07-02 |
| CN105828802B (zh) | 2020-08-04 |
| IL246301A0 (en) | 2016-07-31 |
| AR098921A1 (es) | 2016-06-22 |
| PH12016501053A1 (en) | 2016-07-11 |
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