RU2016111950A - Use of 3,4,5-trimethoxy-N '(2,2,6,6-tetramethyl-piperidin-4-ylidene) benzohydrazide hydrochloride as an anxiolytic agent - Google Patents

Use of 3,4,5-trimethoxy-N '(2,2,6,6-tetramethyl-piperidin-4-ylidene) benzohydrazide hydrochloride as an anxiolytic agent Download PDF

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Publication number
RU2016111950A
RU2016111950A RU2016111950A RU2016111950A RU2016111950A RU 2016111950 A RU2016111950 A RU 2016111950A RU 2016111950 A RU2016111950 A RU 2016111950A RU 2016111950 A RU2016111950 A RU 2016111950A RU 2016111950 A RU2016111950 A RU 2016111950A
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RU
Russia
Prior art keywords
ylidene
trimethoxy
piperidin
tetramethyl
anxiolytic agent
Prior art date
Application number
RU2016111950A
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Russian (ru)
Other versions
RU2016111950A3 (en
RU2691454C2 (en
Inventor
Полина Леонидовна Наплёкова
Виктор Борисович Наркевич
Татьяна Александровна Воронина
Владимир Сергеевич Кудрин
Леонид Михайлович Косточка
Никита Викторович Кудряшов
Original Assignee
Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" filed Critical Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова"
Priority to RU2016111950A priority Critical patent/RU2691454C2/en
Publication of RU2016111950A publication Critical patent/RU2016111950A/en
Publication of RU2016111950A3 publication Critical patent/RU2016111950A3/ru
Application granted granted Critical
Publication of RU2691454C2 publication Critical patent/RU2691454C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/452—Piperidinium derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (1)

Применение 3,4,5-триметокси-N'(2,2,6,6-тетраметил-пиперидин-4-илиден)бензогидразида гидрохлорида в качестве анксиолитического средства.The use of 3,4,5-trimethoxy-N '(2,2,6,6-tetramethyl-piperidin-4-ylidene) benzohydrazide hydrochloride as an anxiolytic agent.
RU2016111950A 2016-03-30 2016-03-30 Use of 3,4,5-trimethoxy-n'(2,2,6,6-tetramethyl-piperidin-4-ylidene)benzohydrazide hydrochloride as an anxiolytic agent RU2691454C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016111950A RU2691454C2 (en) 2016-03-30 2016-03-30 Use of 3,4,5-trimethoxy-n'(2,2,6,6-tetramethyl-piperidin-4-ylidene)benzohydrazide hydrochloride as an anxiolytic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016111950A RU2691454C2 (en) 2016-03-30 2016-03-30 Use of 3,4,5-trimethoxy-n'(2,2,6,6-tetramethyl-piperidin-4-ylidene)benzohydrazide hydrochloride as an anxiolytic agent

Publications (3)

Publication Number Publication Date
RU2016111950A true RU2016111950A (en) 2017-10-05
RU2016111950A3 RU2016111950A3 (en) 2019-04-25
RU2691454C2 RU2691454C2 (en) 2019-06-14

Family

ID=60047511

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016111950A RU2691454C2 (en) 2016-03-30 2016-03-30 Use of 3,4,5-trimethoxy-n'(2,2,6,6-tetramethyl-piperidin-4-ylidene)benzohydrazide hydrochloride as an anxiolytic agent

Country Status (1)

Country Link
RU (1) RU2691454C2 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
KR20080070848A (en) * 2005-11-03 2008-07-31 레드포인트 바이오 코포레이션 Hydrazone derivatives and uses thereof
RU2421222C2 (en) * 2009-06-26 2011-06-20 Учреждение Российской академии медицинских наук Научно-исследовательский институт фармакологии имени В.В. Закусова РАМН Agent for prevention and correction of motor, extrapyramidal disturbances induced by neuroleptics
RU2519191C1 (en) * 2013-02-19 2014-06-10 Общество с ограниченной ответственностью "Научно-производственное объединение "МедФармСинтез" Medication, possessing anxiolytic activity

Also Published As

Publication number Publication date
RU2016111950A3 (en) 2019-04-25
RU2691454C2 (en) 2019-06-14

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20210331