RU2015131803A - GLUTARIMID DERIVATIVES, THEIR APPLICATION, PHARMACEUTICAL COMPOSITION BASED ON THEM, METHODS FOR PRODUCING THEM - Google Patents

GLUTARIMID DERIVATIVES, THEIR APPLICATION, PHARMACEUTICAL COMPOSITION BASED ON THEM, METHODS FOR PRODUCING THEM Download PDF

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RU2015131803A
RU2015131803A RU2015131803A RU2015131803A RU2015131803A RU 2015131803 A RU2015131803 A RU 2015131803A RU 2015131803 A RU2015131803 A RU 2015131803A RU 2015131803 A RU2015131803 A RU 2015131803A RU 2015131803 A RU2015131803 A RU 2015131803A
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pharmaceutical composition
pharmaceutically acceptable
respiratory tract
upper respiratory
glutarimid
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RU2015131803A
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Russian (ru)
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RU2610275C2 (en
Inventor
Владимир Евгеньевич Небольсин
Татьяна Александровна Кромова
Галина Александровна Желтухина
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Общество С Ограниченной Ответственностью "Фарминтерпрайсез"
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (11)

1. Соединение формулы1. The compound of the formula
Figure 00000001
Figure 00000001
 или его фармацевтически приемлемая соль.or a pharmaceutically acceptable salt thereof. 2. Лекарственное средство для лечения заболеваний верхних дыхательных путей, представляющее собой соединение по п.1 или его фармацевтически приемлемую соль.2. A drug for the treatment of diseases of the upper respiratory tract, which is a compound according to claim 1 or its pharmaceutically acceptable salt. 3. Лекарственное средство по п.2, где заболевание верхних дыхательных путей представляет собой риносинусит.3. The drug according to claim 2, where the disease of the upper respiratory tract is rhinosinusitis. 4. Фармацевтическая композиция для лечения заболеваний верхних дыхательных путей, включающая эффективное количество соединения по п.1 или его фармацевтически приемлемой соли и фармацевтически приемлемые наполнители.4. A pharmaceutical composition for treating diseases of the upper respiratory tract, comprising an effective amount of a compound according to claim 1 or a pharmaceutically acceptable salt thereof and pharmaceutically acceptable excipients. 5. Фармацевтическая композиция по п.4, где заболевание верхних дыхательных путей представляет собой риносинусит.5. The pharmaceutical composition according to claim 4, where the upper respiratory tract disease is rhinosinusitis. 6. Способ лечения заболеваний верхних дыхательных путей, включающий введение пациенту эффективного количества соединения по п.1 или его фармацевтически приемлемой соли.6. A method of treating diseases of the upper respiratory tract, comprising administering to the patient an effective amount of a compound according to claim 1 or a pharmaceutically acceptable salt thereof. 7. Способ по п.6, где заболевание представляет собой риносинусит.7. The method according to claim 6, where the disease is rhinosinusitis. 8. Применение соединения по п.1 или его фармацевтически приемлемой соли для получения лекарственного средства для лечения заболеваний верхних дыхательных путей.8. The use of a compound according to claim 1 or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of diseases of the upper respiratory tract. 9. Применение по п.8, где заболевание представляет собой риносинусит.9. The use of claim 8, where the disease is rhinosinusitis.
RU2015131803A 2015-07-30 2015-07-30 Glutarimide derivative, use thereof, pharmaceutical composition based thereon, synthesis method thereof RU2610275C2 (en)

Priority Applications (1)

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RU2015131803A RU2610275C2 (en) 2015-07-30 2015-07-30 Glutarimide derivative, use thereof, pharmaceutical composition based thereon, synthesis method thereof

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RU2015131803A RU2610275C2 (en) 2015-07-30 2015-07-30 Glutarimide derivative, use thereof, pharmaceutical composition based thereon, synthesis method thereof

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RU2013116826A Division RU2562773C3 (en) 2013-04-12 2013-04-12 GLUTARIMIDE DERIVATIVES, THEIR APPLICATION, PHARMACEUTICAL COMPOSITION BASED ON THEM, METHODS OF THEIR PRODUCTION

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RU2770521C2 (en) * 2020-02-11 2022-04-18 Общество С Ограниченной Ответственностью "Валента-Интеллект" Liquid dosage form for treatment and prevention of flu and arvi

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DE10002509A1 (en) * 2000-01-21 2001-07-26 Gruenenthal Gmbh New substituted glutarimide derivatives are IL-12 antagonists, are useful as immunomodulators and for the treatment of angiopathy, hematological or oncological disorders

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