RU2013142835A - METHOD FOR TREATING ISCHEMIC STROKE - Google Patents
METHOD FOR TREATING ISCHEMIC STROKE Download PDFInfo
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- RU2013142835A RU2013142835A RU2013142835/15A RU2013142835A RU2013142835A RU 2013142835 A RU2013142835 A RU 2013142835A RU 2013142835/15 A RU2013142835/15 A RU 2013142835/15A RU 2013142835 A RU2013142835 A RU 2013142835A RU 2013142835 A RU2013142835 A RU 2013142835A
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- ischemic stroke
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- patient
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Abstract
1. Композиция для лечения ишемического инсульта, представляющая собой раствор для инъекционного введения, содержащий в качестве активного вещества убидекаренон и вспомогательные добавки.2. Композиция по п.1, отличающаяся тем, что раствор является стерильным.3. Композиция по п.1, отличающаяся тем, что убидекаренон используется в солюбилизированной форме.4. Композиция по п.1, отличающаяся тем, что в качестве вспомогательных добавок используют аскорбил пальмитат, и/или натрия бензоат и/или лимонную кислоту.5. Способ лечения ишемического инсульта, включающий инъекционное введение пациенту фармакологически эффективного количества убидекаренона.6. Способ по п.5, отличающий тем, что инъекционное введение представляет собой внутривенное введение.7. Способ по п.5, отличающийся тем, что при остром ишемическом инсульте пациенту вводят композицию по п.1 в виде внутривенной однократной инъекции в дозе 5-10 мг/кг.8. Способ по п.5, отличающий тем, что при остром ишемическом инсульте пациенту вводят композицию по п.1 в виде двукратной внутривенной инъекции в дозе 5-10 мг/кг в остром периоде и через 6 часов после первой инъекции.9. Способ по п.5, отличающийся тем, что при остром ишемическом инсульте пациенту вводят композицию по п.1 в виде однократной болюсной внутривенной инъекции в дозе 5-10 мг/кг, с последующим внутривенным капельным введением в дозе 5-10 мг/кг в 200 мл физиологического раствора через 2 часа после первой инъекции.10. Способ по п.5, отличающийся тем, что при остром ишемическом инсульте пациенту вводят композицию по п.1 в виде однократной внутривенной инъекции в дозе 5-10 мг/кг с последующий ежедневным внутривенным капельным введени�1. Composition for the treatment of ischemic stroke, which is a solution for injection, containing ubidecarenone and auxiliary additives as an active substance. The composition according to claim 1, characterized in that the solution is sterile. The composition according to claim 1, characterized in that ubidecarenone is used in solubilized form. The composition according to claim 1, characterized in that ascorbyl palmitate and / or sodium benzoate and / or citric acid are used as auxiliary additives. A method of treating ischemic stroke, comprising injecting the patient with a pharmacologically effective amount of ubidecarenone. 6. The method according to claim 5, characterized in that the injection is an intravenous administration. The method according to claim 5, characterized in that in acute ischemic stroke the patient is administered the composition according to claim 1 in the form of a single intravenous injection at a dose of 5-10 mg / kg. The method according to claim 5, characterized in that in an acute ischemic stroke, the patient is administered the composition according to claim 1 in the form of a double intravenous injection at a dose of 5-10 mg / kg in the acute period and 6 hours after the first injection. The method according to claim 5, characterized in that for acute ischemic stroke the patient is administered the composition according to claim 1 in the form of a single bolus intravenous injection at a dose of 5-10 mg / kg, followed by intravenous drip at a dose of 5-10 mg / kg 200 ml of saline 2 hours after the first injection. 10. The method according to claim 5, characterized in that for acute ischemic stroke, the patient is administered the composition according to claim 1 in the form of a single intravenous injection at a dose of 5-10 mg / kg, followed by daily intravenous drip
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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RU2013142835/15A RU2554500C2 (en) | 2013-09-20 | 2013-09-20 | Method of treating ischemic stroke |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2013142835/15A RU2554500C2 (en) | 2013-09-20 | 2013-09-20 | Method of treating ischemic stroke |
Publications (2)
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RU2013142835A true RU2013142835A (en) | 2015-04-10 |
RU2554500C2 RU2554500C2 (en) | 2015-06-27 |
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RU2013142835/15A RU2554500C2 (en) | 2013-09-20 | 2013-09-20 | Method of treating ischemic stroke |
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Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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RU2643943C2 (en) * | 2016-05-06 | 2018-02-06 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный медицинский университет им. Н.Н. Бурденко" Министерства здравоохранения Российской Федерации | Method of evaluation and correction of neurological status based on the monitoring of oxidative stress parameters in patients with ischemic stroke |
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PL212952B1 (en) * | 2000-10-26 | 2012-12-31 | Fournier Lab Ireland Ltd | Combination of fenofibrate and coenzyme q10 for the treatment of endothelial dysfunction |
RU2385722C1 (en) * | 2008-07-02 | 2010-04-10 | Тимофей Георгиевич Кожока | Pharmaceutical neuroprotective, antioxidant, antihypoxic, antiapoptotic and membrane protective composition and method of treatment |
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