RU2005134223A - Композиции, содержащие штаммы lactobacillus plantarum в сочетании с танином и новые штаммы lactobacillus plantarum - Google Patents
Композиции, содержащие штаммы lactobacillus plantarum в сочетании с танином и новые штаммы lactobacillus plantarum Download PDFInfo
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- RU2005134223A RU2005134223A RU2005134223/13A RU2005134223A RU2005134223A RU 2005134223 A RU2005134223 A RU 2005134223A RU 2005134223/13 A RU2005134223/13 A RU 2005134223/13A RU 2005134223 A RU2005134223 A RU 2005134223A RU 2005134223 A RU2005134223 A RU 2005134223A
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- Prior art keywords
- lactobacillus plantarum
- dsm
- tannase
- lactobacillus
- producing strain
- Prior art date
Links
- 240000006024 Lactobacillus plantarum Species 0.000 title claims abstract 24
- 235000013965 Lactobacillus plantarum Nutrition 0.000 title claims abstract 21
- 229940072205 lactobacillus plantarum Drugs 0.000 title claims abstract 21
- 239000000203 mixture Substances 0.000 title claims abstract 8
- 108010038851 tannase Proteins 0.000 claims abstract 15
- 241000186660 Lactobacillus Species 0.000 claims abstract 7
- 210000004347 intestinal mucosa Anatomy 0.000 claims abstract 7
- 235000018553 tannin Nutrition 0.000 claims abstract 5
- 229920001864 tannin Polymers 0.000 claims abstract 5
- 239000001648 tannin Substances 0.000 claims abstract 5
- 230000000694 effects Effects 0.000 claims abstract 3
- 229940039696 lactobacillus Drugs 0.000 claims 5
- 241000894007 species Species 0.000 claims 5
- 235000013305 food Nutrition 0.000 claims 3
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 206010017964 Gastrointestinal infection Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000003178 anti-diabetic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 239000000824 cytostatic agent Substances 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 230000001777 nootropic effect Effects 0.000 abstract 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/04—Antibacterial agents
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- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/25—Lactobacillus plantarum
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/0102—Tannase (3.1.1.20)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
- Y10S435/857—Lactobacillus plantarum
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- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Engineering & Computer Science (AREA)
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- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
Claims (14)
1. Композиция, содержащая один или более продуцирующих танназу штаммов Lactobacillus plantarum или близкородственных видов Lactobacillus со способностью к адгезии к слизистой оболочке кишечника человека в сочетании с танином.
2. Композиция по п.1, дополнительно содержащая носитель.
3. Композиция по п.1 или 2, являющаяся пищевой композицией.
4. Композиция по п.1 или 2, являющаяся фармацевтической композиции.
5. Композиция по п.2, содержащая продуцирующий танназу штамм Lactobacillus plantarum.
6. Выделенный продуцирующий танназу штамм Lactobacillus plantarum или близкородственные виды Lactobacillus со способностью к адгезии к слизистой оболочке кишечника человека, характеризующиеся наличием количественной танназной активности более чем 6,2, определяемой способом, описанным Osawa и Walsh, за исключением штаммов Lactobacillus plantarum 299, DSM 6595 и Lactobacillus plantarum 299v, DSM 9843.
7. Выделенный продуцирующий танназу штамм по п.6, представляющий собой Lactobacillus plantarum HEAL 9, DSM 15312.
8. Выделенный продуцирующий танназу штамм по п.6, представляющий собой Lactobacillus plantarum HEAL 19, DSM 15313.
9. Выделенный продуцирующий танназу штамм по п.6, представляющий собой Lactobacillus plantarum HEAL 99, DSM 15316.
10. Применение продуцирующего танназу штамма Lactobacillus plantarum или близкородственных видов Lactobacillus со способностью к адгезии к слизистой оболочке кишечника человека в сочетании с танином для получения лекарственного средства для профилактического или терапевтического лечения сердечно-сосудистых заболеваний, диабета, воспалительных заболеваний кишечника (IBD), синдрома раздраженной кишки (IBS), желудочно-кишечных инфекций, злокачественной опухоли, болезни Альцгеймера или заболеваний аутоиммунного происхождения.
11. Применение продуцирующего танназу штамма по п.10, выбранного из группы, состоящей из Lactobacillus plantarum HEAL 9, DSM 15312, Lactobacillus plantarum HEAL 19, DSM 15313, и Lactobacillus plantarum HEAL 99, DSM 15316.
12. Применение продуцирующего танназу штамма Lactobacillus plantarum или близкородственных видов Lactobacillus со способностью к адгезии к слизистой оболочке кишечника человека в сочетании с танином для консервации пищевых продуктов.
13. Применение продуцирующего танназу штамма по п.12, выбранного из группы, состоящей из Lactobacillus plantarum HEAL 9, DSM 15312, Lactobacillus plantarum HEAL 19, DSM 15313, и Lactobacillus plantarum HEAL 99, DSM 15316, Lactobacillus plantarum 299v, DSM 9843.
14. Применение продуцирующего танназу штамма Lactobacillus plantarum или близкородственных видов Lactobacillus со способностью к адгезии к слизистой оболочке кишечника человека в сочетании с танином для получения новых пищевых продуктов.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300994-1 | 2003-04-04 | ||
| SE0300994A SE527555C2 (sv) | 2003-04-04 | 2003-04-04 | Anti-inflammatorisk komposition innehållande tannasproducerande Lactobacillusstammar |
| US46305803P | 2003-04-16 | 2003-04-16 | |
| US60/463,058 | 2003-04-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2005134223A true RU2005134223A (ru) | 2006-03-10 |
| RU2356942C2 RU2356942C2 (ru) | 2009-05-27 |
Family
ID=20290933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005134223/13A RU2356942C2 (ru) | 2003-04-04 | 2004-04-02 | Композиция, обладающая противовоспалительными свойствами, штамм lactobacillus plantarum - продуцент танназы (варианты) и его применения |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | USRE46718E1 (ru) |
| EP (2) | EP1613740B1 (ru) |
| JP (1) | JP4731469B2 (ru) |
| KR (1) | KR101122916B1 (ru) |
| CN (2) | CN1798831B (ru) |
| AT (1) | ATE546516T1 (ru) |
| AU (1) | AU2004225568B2 (ru) |
| BR (2) | BRPI0409206C1 (ru) |
| CA (1) | CA2521220C (ru) |
| DK (1) | DK1613740T3 (ru) |
| ES (2) | ES2382930T3 (ru) |
| HK (2) | HK1094004A1 (ru) |
| PL (2) | PL1613740T3 (ru) |
| PT (1) | PT1613740E (ru) |
| RU (1) | RU2356942C2 (ru) |
| SE (1) | SE527555C2 (ru) |
| SI (1) | SI1613740T1 (ru) |
| WO (1) | WO2004087893A1 (ru) |
| ZA (1) | ZA200507938B (ru) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE528382C2 (sv) | 2004-10-05 | 2006-10-31 | Probi Ab | Probiotiska lactobacillusstammar för förbättrad vaginal hälsa |
| SE529199C2 (sv) * | 2005-07-05 | 2007-05-29 | Probi Ab | Förstärkt absorption |
| WO2007009187A1 (en) * | 2005-07-22 | 2007-01-25 | Tarac Technologies Pty Ltd | Polyphenol and probiotic containing nutritional supplement |
| DK1931363T3 (en) | 2005-09-28 | 2016-02-22 | Nordisk Rebalance As | Treatment of IBD using both probiotic bacteria and fermented cereal as behandlingseffektorer |
| EP1951273B1 (en) * | 2005-10-06 | 2014-02-12 | Probi Ab | Use of lactobacillus for treatment of autoimmune diseases |
| US20080269142A1 (en) * | 2006-10-23 | 2008-10-30 | Ian Blair | Endogenous thiadiazabicyclo glutathione-adduct |
| WO2008075949A1 (en) * | 2006-12-20 | 2008-06-26 | Friesland Brands B.V. | Modulation of human microsomal triglyceride transfer protein (mtp or mttp) gene expression by food-grade/ingested dietary microorganisms |
| JP5829005B2 (ja) * | 2007-03-01 | 2015-12-09 | プロビ アーベー | 細菌多様性を増大させるためのラクトバチルス・プランタルムの使用 |
| SE532899C2 (sv) * | 2007-06-08 | 2010-05-04 | Probi Ab | Förfarande genom fermentering med Lactobacillus plantarum för tillhandahållande av en insulinsvarsreducerande produkt och dess användning farmaceutiskt eller i livsmedel |
| KR20110004407A (ko) * | 2008-04-30 | 2011-01-13 | 네스텍 소시에테아노님 | 가수분해된 클로로겐산을 포함하는 커피 음료 제조용 조성물 |
| CA2723054C (en) * | 2008-04-30 | 2016-12-13 | Nestec S.A. | Products comprising, and uses of, decarboxylated phenolic acids derived from chlorogenic acids of coffee |
| EE05341B1 (et) * | 2008-05-13 | 2010-08-16 | O� Tervisliku Piima Biotehnoloogiate Arenduskeskus | Isoleeritud mikroorganismi tvi Lactobacillus plantarum Inducia DSM 21379 kui organismi loomulikku kaitsev?imet t?stev probiootik, seda sisaldav toiduaine ja kompositsioon ning mikroorganismi kasutamine rakulist immuunsust t?stva ravimi valmistamisek |
| EP2210504A1 (en) * | 2009-01-27 | 2010-07-28 | Nestec S.A. | Composition comprising chicoric acid and/or derivatives thereof |
| EP2210505A1 (en) * | 2009-01-27 | 2010-07-28 | Nestec S.A. | Composition comprising caftaric acid and/or derivatives thereof |
| EP2485744A4 (en) * | 2009-10-09 | 2014-01-22 | Prothera Inc | COMPOSITIONS AND METHODS COMPRISING THE PEDIOCOCCUS TO REDUCE AT LEAST ONE SYMPTOM ASSOCIATED WITH DEVELOPMENT-INVASIVE DISORDER IN A PERSON IN WHICH A DEVELOPMENT-INVASIVE DISORDER HAS BEEN DIAGNOSED |
| RU2580040C2 (ru) | 2009-12-22 | 2016-04-10 | Проби Аб | Неферментированные композиции, включающие фракцию на основе злаков и пробиотик, и их применение |
| TWI401086B (zh) * | 2010-07-20 | 2013-07-11 | Univ China Medical | 胚芽乳酸桿菌及其用途 |
| ITMI20110793A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati. |
| JP6033290B2 (ja) * | 2011-06-10 | 2016-11-30 | 株式会社アモーレパシフィックＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ | チャノキ葉から分離した新規なラクトバチルス・プランタラム |
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| RU2600445C1 (ru) * | 2015-09-21 | 2016-10-20 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московская государственная академия ветеринарной медицины и биотехнологии - МВА имени К.И. Скрябина" (ФГБОУ ВО МГАВМиБ - МВА имени К.И. Скрябина) | Способ биоиндикации состояния двухстворчатых моллюсков в условиях техногенного загрязнения среды обитания |
| GB201600975D0 (en) | 2016-01-19 | 2016-03-02 | Probi Ab | Novel strain of probiotic bacteria and compositions and uses thereof |
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| CN114107161B (zh) * | 2021-11-15 | 2023-06-20 | 泸州老窖股份有限公司 | 一种混合驯化菌株降解石榴皮生产鞣花酸的方法 |
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| JP4127863B2 (ja) | 1993-03-04 | 2008-07-30 | 太陽化学株式会社 | 腸内環境改善組成物 |
| SE9501056D0 (sv) * | 1995-03-23 | 1995-03-23 | Probi Ab | Epithelial adherent lactobacilli |
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| SE510753C2 (sv) * | 1997-08-05 | 1999-06-21 | Probi Ab | Användning av en stam av Lactobacillus för tillverkning av ett läkemedel för reduktion av fibrinogenhalten i blod |
| KR20010075495A (ko) * | 1998-10-01 | 2001-08-09 | 추후보정 | 산화성 스트레스 인자의 감소 |
| FR2789580A1 (fr) | 1999-02-12 | 2000-08-18 | Oreal | Compositions cosmetiques antisolaires a base d'un melange synergique de filtres et utilisations |
| SE523771C2 (sv) * | 1999-05-21 | 2004-05-18 | Probi Ab | Sportdryck innehållande mikronäringsämnen i kombination med levande laktobaciller |
| SE0004124D0 (sv) * | 2000-11-10 | 2000-11-10 | Probi Ab | New use |
| KR100549193B1 (ko) * | 2002-10-23 | 2006-02-02 | (주)바이오뉴트리젠 | 인삼 및 폴리페놀계 물질 또는 바이오플라보노이드계 물질을 포함하는 식물의 분말 또는 추출물을 포함하는 항비만용 식품 |
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