RS52638B - Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors - Google Patents

Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Info

Publication number
RS52638B
RS52638B RS20130038A RSP20130038A RS52638B RS 52638 B RS52638 B RS 52638B RS 20130038 A RS20130038 A RS 20130038A RS P20130038 A RSP20130038 A RS P20130038A RS 52638 B RS52638 B RS 52638B
Authority
RS
Serbia
Prior art keywords
class
inhibitors
combination
histone
histone deacetylase
Prior art date
Application number
RS20130038A
Other languages
Serbian (sr)
Inventor
Janine Arts
Peter Willem Jan Hellemans
Michel Marie François Janicot
Martin John Page
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority claimed from PCT/EP2007/059518 external-priority patent/WO2008031817A2/en
Publication of RS52638B publication Critical patent/RS52638B/en

Links

Abstract

Kombinacija, naznačena time, da obuhvata inhibitor proteasoma, pri čemu je pomenuti inhibitor proteasoma bortezomib, i inhibitor histonske deacetilaze, pri čemu je pomenuti inhibitor histonske deacetilaze jedinjenje Br. 1a (JNJ26481585)njegove farmaceutski prihvatljive kisele i bazne adicione soli i stereohemijski izomerne forme.Prijava sadrži još 7 patentnih zahteva.The combination comprising a proteasome inhibitor, said proteasome inhibitor being bortezomib, and a histone deacetylase inhibitor, said histone deacetylase inhibitor being compound Br. 1a (JNJ26481585) its pharmaceutically acceptable acid and base addition salts and stereochemically isomeric forms. The application contains 7 more claims.

RS20130038A 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors RS52638B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06120726 2006-09-15
US91589507P 2007-05-03 2007-05-03
PCT/EP2007/059518 WO2008031817A2 (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Publications (1)

Publication Number Publication Date
RS52638B true RS52638B (en) 2013-06-28

Family

ID=41040414

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20130038A RS52638B (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Country Status (12)

Country Link
CN (1) CN101516374B (en)
BR (1) BRPI0716992A2 (en)
DK (1) DK2066327T3 (en)
ES (1) ES2399670T3 (en)
ME (1) ME01514B (en)
NZ (1) NZ575030A (en)
PT (1) PT2066327E (en)
RS (1) RS52638B (en)
SG (1) SG177219A1 (en)
SI (1) SI2066327T1 (en)
UA (1) UA97249C2 (en)
ZA (1) ZA200901818B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957066B2 (en) * 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
CN107095871A (en) * 2016-02-22 2017-08-29 中国科学院上海巴斯德研究所 Quisinostat, a kind of new efficient antimalarial agent
US10653648B2 (en) * 2016-07-20 2020-05-19 The Trustees Of Columbia University In The City Of New York Histone acetyltransferase activators and compositions and uses thereof
CN114409638B (en) * 2022-02-09 2023-02-14 深圳大学 Histone deacetylase 8 selective degradation agent, preparation method and application thereof in antitumor activity
CN115028678A (en) * 2022-07-08 2022-09-09 杭州医学院 Bifunctional molecule based on BCR-ABL protein degradation induced by VHL ligand and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006010750A1 (en) * 2004-07-28 2006-02-02 Janssen Pharmaceutica N.V. Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Also Published As

Publication number Publication date
SG177219A1 (en) 2012-01-30
DK2066327T3 (en) 2013-02-11
BRPI0716992A2 (en) 2013-09-17
NZ575030A (en) 2012-07-27
UA97249C2 (en) 2012-01-25
ZA200901818B (en) 2010-05-26
ES2399670T3 (en) 2013-04-02
ME01514B (en) 2014-04-20
PT2066327E (en) 2013-02-06
CN101516374B (en) 2013-04-24
SI2066327T1 (en) 2013-04-30
CN101516374A (en) 2009-08-26

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