RO94021B - Procedeu de obtinere a unui factor angiogenic - Google Patents
Procedeu de obtinere a unui factor angiogenicInfo
- Publication number
- RO94021B RO94021B RO123075A RO12307586A RO94021B RO 94021 B RO94021 B RO 94021B RO 123075 A RO123075 A RO 123075A RO 12307586 A RO12307586 A RO 12307586A RO 94021 B RO94021 B RO 94021B
- Authority
- RO
- Romania
- Prior art keywords
- minutes
- obtaning
- centrifuged
- volumes
- phosphate buffer
- Prior art date
Links
- 239000002870 angiogenesis inducing agent Substances 0.000 title 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000008363 phosphate buffer Substances 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000282324 Felis Species 0.000 abstract 1
- WORJEOGGNQDSOE-UHFFFAOYSA-N chloroform;methanol Chemical compound OC.ClC(Cl)Cl WORJEOGGNQDSOE-UHFFFAOYSA-N 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 210000002747 omentum Anatomy 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Inorganic Insulating Materials (AREA)
Abstract
Procedeul, conform inventiei, consta în aceea ca omentumul de felina, bovina sau porcina, izolat de la femelele adulte, este maruntit si amestecat cu 300 vol solutie tampon fosfat salin la 4 degree C, dupa care se centrifugheaza 5 min la o turatie de 20500 rot/min so apoi 20 min la 1600×g, stratul lipidic obtinut este omogenizat, timp de 2 min, cu 21 vol amestec cloroform-metanol, apoi centrifugat timp de 10 min la temperatura camerei si la 200×g, dupa care supernatantul obtinut este evaporat în vid la 37 degree C si, în vederea utilizarii, este adus în suspensie cu 4 vol solutie tampon de fosfat salin.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/642,624 US4699788A (en) | 1984-08-20 | 1984-08-20 | Angiogenic factor methods of extraction and method for producing angiogenesis |
Publications (2)
Publication Number | Publication Date |
---|---|
RO94021A RO94021A (ro) | 1988-03-30 |
RO94021B true RO94021B (ro) | 1988-03-31 |
Family
ID=24577348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO123075A RO94021B (ro) | 1984-08-20 | 1986-04-21 | Procedeu de obtinere a unui factor angiogenic |
Country Status (12)
Country | Link |
---|---|
US (1) | US4699788A (ro) |
EP (1) | EP0191804A1 (ro) |
JP (1) | JPS62500026A (ro) |
KR (1) | KR870700359A (ro) |
AU (1) | AU584914B2 (ro) |
BR (1) | BR8506887A (ro) |
CA (1) | CA1261258A (ro) |
DK (1) | DK179086A (ro) |
FI (1) | FI861654A (ro) |
NO (1) | NO861553L (ro) |
RO (1) | RO94021B (ro) |
WO (1) | WO1986001111A1 (ro) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4897464A (en) * | 1985-04-17 | 1990-01-30 | President And Fellows Of Harvard College | Purified protein having angiogenic activity and methods of preparation |
US4710490A (en) * | 1985-10-01 | 1987-12-01 | Angio Medical Corporation | Compositions containing ganglioside molecules with enhanced angiogenic activity |
US4767746A (en) * | 1985-12-04 | 1988-08-30 | Trustees Of Boston University | Method for enhancement of healing of epithelial wounds in mammals |
US4990333A (en) * | 1985-12-20 | 1991-02-05 | Angio Medical Corporation | Method for healing bone damage |
US4879114A (en) * | 1985-12-20 | 1989-11-07 | Angio-Medical Corporation | Lipids from omentum and methods for cosmetic use |
US4778787A (en) * | 1985-12-20 | 1988-10-18 | Trustees Of Boston University | Method for treatment of angina and myocardial infarctions with omental lipids |
EP0274547A1 (en) * | 1986-12-18 | 1988-07-20 | Trustees Of Boston University | Method for enhancement of healing of epithelial wounds in mammals |
IL84864A0 (en) * | 1986-12-31 | 1988-06-30 | Univ Boston | Composition for promoting hair growth containing omental lipids and process for promoting hair growth utilizing the same |
GB8708009D0 (en) * | 1987-04-03 | 1987-05-07 | Clayton Found Res | Injectable soft tissue augmentation materials |
US4952403A (en) * | 1987-06-19 | 1990-08-28 | President And Fellows Of Harvard College | Implants for the promotion of healing of meniscal tissue |
US4952404A (en) * | 1987-06-19 | 1990-08-28 | President And Fellows Of Harvard College | Promotion of healing of meniscal tissue |
US4853219A (en) * | 1987-08-06 | 1989-08-01 | President And Fellows Of Harvard College | Antibodies to angiogenin: immunotherapeutic agents |
US4940730A (en) * | 1987-10-29 | 1990-07-10 | Takeda Chemical Industries, Ltd. | Angiogenesis enhancer |
US4879312A (en) * | 1988-03-07 | 1989-11-07 | Angio Medical Corporation | Method for enhancing or provoking angiogenesis using angiogenically active omega-3 polyunsaturated fatty acids |
IE891173L (en) * | 1988-04-18 | 1989-10-18 | Univ Utrecht | Composition for promoting hair growth in androgenetic¹alopecia and method thereof |
EP0717630A1 (de) * | 1994-07-08 | 1996-06-26 | SULZER Medizinaltechnik AG | Verfahren zur herstellung von implantationsmaterialien |
US5733884A (en) * | 1995-11-07 | 1998-03-31 | Nestec Ltd. | Enteral formulation designed for optimized wound healing |
DE69733815T2 (de) | 1996-02-15 | 2006-06-08 | Biosense Webster, Inc., Diamond Bar | Sonde zur exkavation |
US6443974B1 (en) * | 1996-07-28 | 2002-09-03 | Biosense, Inc. | Electromagnetic cardiac biostimulation |
WO1998005307A1 (en) * | 1996-08-08 | 1998-02-12 | Localmed, Inc. | Transmural drug delivery method and apparatus |
WO1998019626A2 (en) * | 1996-11-05 | 1998-05-14 | Localmed, Inc. | Method and device for continuous intralumenal delivery of bioactive substances |
US20030113303A1 (en) * | 1998-02-05 | 2003-06-19 | Yitzhack Schwartz | Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances |
ES2293473T3 (es) | 1998-02-05 | 2008-03-16 | Biosense Webster, Inc. | Administracion intracardiaca de farmaco. |
US20030129750A1 (en) * | 1998-02-05 | 2003-07-10 | Yitzhack Schwartz | Homing of donor cells to a target zone in tissue using active therapeutics or substances |
CA2329010A1 (en) * | 1998-04-17 | 1999-10-28 | Angiogenix Incorporated | Therapeutic angiogenic factors and methods for their use |
US6211157B1 (en) | 1998-05-01 | 2001-04-03 | Sulzer Biologics, Inc. | Protein mixtures to induce therapeutic angiogenesis |
US7087577B2 (en) * | 1998-10-16 | 2006-08-08 | Zimmer Orthobiologies, Inc. | Method of promoting natural bypass |
US6992066B2 (en) | 1998-10-16 | 2006-01-31 | Zimmer Orthobiologics, Inc. | Povidone-containing carriers for polypeptide growth factors |
US7585670B2 (en) | 2001-12-07 | 2009-09-08 | Cytori Therapeutics, Inc. | Automated methods for isolating and using clinically safe adipose derived regenerative cells |
US9597395B2 (en) | 2001-12-07 | 2017-03-21 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
US7514075B2 (en) | 2001-12-07 | 2009-04-07 | Cytori Therapeutics, Inc. | Systems and methods for separating and concentrating adipose derived stem cells from tissue |
US7595043B2 (en) | 2001-12-07 | 2009-09-29 | Cytori Therapeutics, Inc. | Method for processing and using adipose-derived stem cells |
KR101150666B1 (ko) | 2001-12-07 | 2012-07-05 | 사이토리 테라퓨틱스, 인크. | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
US20050095228A1 (en) | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
US20050048035A1 (en) | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
US7651684B2 (en) | 2001-12-07 | 2010-01-26 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
US7232802B2 (en) * | 2001-12-21 | 2007-06-19 | Zimmer Orthobiologics, Inc. | Compositions and methods for promoting myocardial and peripheral angiogenesis |
US7241874B2 (en) * | 2002-06-26 | 2007-07-10 | Zimmer Ortho Biologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
US7622562B2 (en) | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
WO2009094340A2 (en) * | 2008-01-26 | 2009-07-30 | Surinder Singh Saini | Omentum and use thereof |
WO2010021993A1 (en) | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
EP2424463B1 (en) | 2009-05-01 | 2016-12-28 | Bimini Technologies LLC | Systems, methods and compositions for optimizing tissue and cell enriched grafts |
MX2013010488A (es) * | 2011-03-25 | 2014-03-31 | Cooperlabs Ltd | Extractos de omento extraidos con calor, composiciones, metodos de preparacion y sus usos. |
IL250881A0 (en) | 2017-03-01 | 2017-06-29 | Pali Nazir | A process of instant creation of artificial bone tissue |
IL257853A (en) | 2018-03-04 | 2019-03-31 | Pali Nazir | Process for building artificial multifunctional injectable filler |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4229531A (en) * | 1978-12-29 | 1980-10-21 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
US4229532A (en) * | 1978-12-29 | 1980-10-21 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
US4210718A (en) * | 1978-12-29 | 1980-07-01 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
US4210719A (en) * | 1978-12-29 | 1980-07-01 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
US4225670A (en) * | 1978-12-29 | 1980-09-30 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
US4209587A (en) * | 1978-12-29 | 1980-06-24 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
US4217412A (en) * | 1979-04-25 | 1980-08-12 | President And Fellows Of Harvard College | Production of tumor angiogenesis factor by cell culture |
US4268629A (en) * | 1980-03-03 | 1981-05-19 | Monsanto Company | Production of angiogenic factor by cell culture |
US4273871A (en) * | 1980-03-03 | 1981-06-16 | Monsanto Company | Production of angiogenic factor by cell culture |
CA1168980A (en) * | 1980-04-17 | 1984-06-12 | Rolf Schafer | Wound healing compositions |
ZA833446B (en) * | 1982-05-28 | 1984-02-29 | Solco Basel Ag | Process for the preparation of cell-and tissue-regenerating substances |
US4529590A (en) * | 1982-12-27 | 1985-07-16 | Leveen Robert F | Production of angiogenetic factor |
-
1984
- 1984-08-20 US US06/642,624 patent/US4699788A/en not_active Expired - Fee Related
-
1985
- 1985-08-01 BR BR8506887A patent/BR8506887A/pt unknown
- 1985-08-01 WO PCT/US1985/001445 patent/WO1986001111A1/en not_active Application Discontinuation
- 1985-08-01 EP EP85903953A patent/EP0191804A1/en not_active Withdrawn
- 1985-08-01 JP JP60503442A patent/JPS62500026A/ja active Pending
- 1985-08-01 AU AU46387/85A patent/AU584914B2/en not_active Ceased
- 1985-08-19 CA CA000488992A patent/CA1261258A/en not_active Expired
-
1986
- 1986-04-18 DK DK179086A patent/DK179086A/da not_active Application Discontinuation
- 1986-04-18 NO NO861553A patent/NO861553L/no unknown
- 1986-04-18 FI FI861654A patent/FI861654A/fi not_active Application Discontinuation
- 1986-04-19 KR KR860700224A patent/KR870700359A/ko not_active Application Discontinuation
- 1986-04-21 RO RO123075A patent/RO94021B/ro unknown
Also Published As
Publication number | Publication date |
---|---|
JPS62500026A (ja) | 1987-01-08 |
DK179086D0 (da) | 1986-04-18 |
CA1261258A (en) | 1989-09-26 |
EP0191804A1 (en) | 1986-08-27 |
WO1986001111A1 (en) | 1986-02-27 |
RO94021A (ro) | 1988-03-30 |
US4699788A (en) | 1987-10-13 |
AU4638785A (en) | 1986-03-07 |
AU584914B2 (en) | 1989-06-08 |
NO861553L (no) | 1986-04-18 |
FI861654A0 (fi) | 1986-04-18 |
DK179086A (da) | 1986-04-18 |
BR8506887A (pt) | 1986-12-09 |
KR870700359A (ko) | 1987-12-28 |
FI861654A (fi) | 1986-04-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RO94021B (ro) | Procedeu de obtinere a unui factor angiogenic | |
Denson et al. | Characterization of the coagulant activity of some snake venoms | |
Cavanaugh et al. | Role of the coagulation system in tumor-cell-induced platelet aggregation and metastasis | |
ATE88097T1 (de) | Verfahren und system zur entfernung von immunosuppressiven bestandteilen aus saeugetierblut. | |
NO891470L (no) | Fremgangsmaate for fremstilling av nye substituerte azetidinoner. | |
ATE123301T1 (de) | Gentechnologisch-hergestellte aprotinin-homologe. | |
SE8504967D0 (sv) | A pharmaceutical composition and a method of treating the body | |
ATE191850T1 (de) | Eichenrindenextraktverwandte synthetische zubereitungen und verfahren zur verwendung | |
DE69329247D1 (de) | Kristallisierung von m-csf | |
ATE82502T1 (de) | Zusammensetzungen zur vorbeugung von plastikabstossung. | |
EP0155852A2 (en) | Thrombin-binding substance and process for its production | |
Tocantins | Cephalin, Protamine and the Antithromboplastic Activity of Normal and Hemophilic Plasmas. | |
DE68905342D1 (de) | Verwendung von minoxidil zur wundheilung. | |
NO934381L (no) | Terapeutiske sammensetninger for osteoinduksjon | |
DK226889A (da) | Alkoholpeptidderivat samt anvendelse deraf til mindskning af blodkoagulation | |
HU205148B (en) | Process for producing amblyommin and process for producing pharmaceutical compositions comprising such compound as active ingredient | |
BR8701146A (pt) | Captador de residuo em particulas do alojamento de turbina de turbocarregadores | |
Barlow et al. | Immunochemical identification of ancrod (A38414) and reptilase (defibrase) | |
Jirgensons | Optical rotatory properties of some abnormal serum globulins | |
RO103682B1 (ro) | Procedeu de izolare a ceruloplasminei umane | |
Bhargava et al. | Comparison of hemorrhagic factors of the venoms of Naja naja, Agkistrodon piscivorus and Apis mellifera | |
DE3879410D1 (de) | Acyl-derivate von hydroxy-pyrimidinen. | |
Kornalik et al. | Procoagulant and defibrinating potency of the venom gland extract of Thelotornis kirtlandi | |
Smith et al. | Inventory of exogenous platelet-aggregating agents derived from venoms | |
ATE30676T1 (de) | Antithrombotische und/oder antihypertensive zusammensetzungen. |