PT97160A - Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo - Google Patents

Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo

Info

Publication number
PT97160A
PT97160A PT97160A PT9716091A PT97160A PT 97160 A PT97160 A PT 97160A PT 97160 A PT97160 A PT 97160A PT 9716091 A PT9716091 A PT 9716091A PT 97160 A PT97160 A PT 97160A
Authority
PT
Portugal
Prior art keywords
polypeptide
preparation
biologically active
parenteral administration
active protein
Prior art date
Application number
PT97160A
Other languages
English (en)
Other versions
PT97160B (pt
Inventor
William Steber
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PT97160A publication Critical patent/PT97160A/pt
Publication of PT97160B publication Critical patent/PT97160B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
PT97160A 1990-03-30 1991-03-27 Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo PT97160B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,382 US5213810A (en) 1990-03-30 1990-03-30 Stable compositions for parenteral administration and method of making same

Publications (2)

Publication Number Publication Date
PT97160A true PT97160A (pt) 1991-11-29
PT97160B PT97160B (pt) 1998-07-31

Family

ID=23997559

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97160A PT97160B (pt) 1990-03-30 1991-03-27 Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo

Country Status (29)

Country Link
US (1) US5213810A (pt)
EP (1) EP0448930B1 (pt)
JP (1) JP2966564B2 (pt)
KR (1) KR0159778B1 (pt)
CN (1) CN1063941C (pt)
AR (1) AR248085A1 (pt)
AT (1) ATE106240T1 (pt)
AU (1) AU641994B2 (pt)
BG (1) BG60850B1 (pt)
CA (1) CA2039491C (pt)
CZ (1) CZ283053B6 (pt)
DE (1) DE69102176T2 (pt)
DK (1) DK0448930T3 (pt)
ES (1) ES2054380T3 (pt)
FI (1) FI101676B1 (pt)
HK (1) HK1000004A1 (pt)
HU (1) HU219584B (pt)
IE (1) IE65970B1 (pt)
IL (1) IL97145A (pt)
MX (1) MX172602B (pt)
NO (1) NO300717B1 (pt)
NZ (1) NZ237509A (pt)
PL (1) PL167692B1 (pt)
PT (1) PT97160B (pt)
RO (1) RO106191B1 (pt)
RU (1) RU2011377C1 (pt)
SK (1) SK279461B6 (pt)
YU (1) YU47650B (pt)
ZA (1) ZA912398B (pt)

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US5599660A (en) * 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
US6083430A (en) * 1994-10-28 2000-07-04 Fuisz Technologies Ltd. Method of preparing a dosage unit by direct tableting and product therefrom
DE69828635T2 (de) * 1997-09-19 2005-06-16 Shire Laboratories, Inc. Feste lösungskügelchen
AU2002300572B2 (en) * 1997-09-19 2004-11-25 Shire Laboratories, Inc. Solid Solution Beadlet
US6117452A (en) * 1998-08-12 2000-09-12 Fuisz Technologies Ltd. Fatty ester combinations
JP2002544155A (ja) * 1999-05-07 2002-12-24 ファルマソル ゲーエムベーハー 流体および固体脂質の混合物を基礎とする脂質粒子、およびそれらを製造するための方法
US8663692B1 (en) * 1999-05-07 2014-03-04 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
PT1187601E (pt) * 1999-06-07 2005-11-30 Altana Pharma Ag Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido
AU2001257359A1 (en) 2000-04-27 2001-11-07 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
TWI268761B (en) * 2000-06-26 2006-12-21 Martek Biosciences Corp Improved methods of incorporating polyunsaturated fatty acids in milk
JP2004509739A (ja) 2000-09-27 2004-04-02 ベリオン　インコーポレイテッド 即時水溶解性カプセルおよびその製法
ATE392887T1 (de) * 2000-10-10 2008-05-15 Wyeth Corp Stabilisierte arzneizusammensetzungen zur parenteralen vearbreichung
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
WO2005053653A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride
BRPI0417338A (pt) * 2003-12-04 2007-04-17 Pfizer Prod Inc formas de dosagem de azitromicina multiparticulada por processos a base de lìquido
BRPI0417348A (pt) * 2003-12-04 2007-03-13 Pfizer Prod Inc processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
PT1691787E (pt) * 2003-12-04 2008-09-02 Pfizer Prod Inc Método de formação de multipartículas farmacêuticas
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
BRPI0416534A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
EP2359808B1 (en) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
EP2157967B1 (en) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspension formulations of insulinotropic peptides and uses thereof
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
CN104248623B (zh) * 2008-09-04 2020-04-03 安米林药品有限责任公司 使用非水性载体的持续释放制剂
JP5494957B2 (ja) 2009-06-11 2014-05-21 株式会社リコー 静電荷像現像用トナー、現像剤、画像形成方法及び画像形成装置
EP3323423B1 (en) 2009-09-28 2020-06-17 Intarcia Therapeutics, Inc Rapid establishment and/or termination of substantial steady-state drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9364549B2 (en) 2011-11-30 2016-06-14 Andreas Voigt Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
US20160151286A1 (en) * 2013-05-29 2016-06-02 Therakine Biodelivery Gmbh Hydrophilic Microparticles, Drug-Delivery Material, Method For Manufacturing Thereof And Methods For Delivery of A Drug-Delivery Composition
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
MA44390A (fr) 2015-06-03 2019-01-23 Intarcia Therapeutics Inc Systèmes de mise en place et de retrait d'implant
SG11201810102SA (en) 2016-05-16 2018-12-28 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
CA3130704A1 (en) * 2019-02-21 2020-08-27 ChromaDex Inc. Use of nicotinamide riboside, nicotinic acid riboside, reduced nicotinyl riboside compounds, and nicotinyl riboside compound derivatives in formulations

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US3147187A (en) * 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
DE3024416C2 (de) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
US4666839A (en) * 1982-12-01 1987-05-19 Amgen Methods and materials for obtaining microbial expression of polypeptides including bovine prolactin
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DE3527356A1 (de) * 1985-07-31 1987-02-05 Degussa Verfahren zur verbesserung der fruchtbarkeit von haustieren
SE462894B (sv) * 1985-10-28 1990-09-17 Biogram Ab Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles

Also Published As

Publication number Publication date
NZ237509A (en) 1993-04-28
DE69102176D1 (de) 1994-07-07
SK279461B6 (sk) 1998-11-04
RU2011377C1 (ru) 1994-04-30
NO911228L (no) 1991-10-01
KR910016322A (ko) 1991-11-05
NO911228D0 (no) 1991-03-26
HUT59834A (en) 1992-07-28
AR248085A1 (es) 1995-06-30
FI101676B (fi) 1998-08-14
HU219584B (hu) 2001-05-28
JPH04221319A (ja) 1992-08-11
ES2054380T3 (es) 1994-08-01
IE911041A1 (en) 1991-10-09
PL289657A1 (en) 1992-01-13
YU47650B (sh) 1995-12-04
DE69102176T2 (de) 1995-01-05
BG60850B1 (bg) 1996-05-31
HK1000004A1 (en) 1997-10-03
YU57091A (sh) 1994-01-20
JP2966564B2 (ja) 1999-10-25
FI911531A (fi) 1991-10-01
CZ283053B6 (cs) 1997-12-17
MX172602B (es) 1993-01-03
AU641994B2 (en) 1993-10-07
ZA912398B (en) 1992-01-29
FI911531A0 (fi) 1991-03-28
CA2039491A1 (en) 1991-10-01
CN1055293A (zh) 1991-10-16
IE65970B1 (en) 1995-11-29
CA2039491C (en) 2001-09-04
KR0159778B1 (ko) 1998-12-01
HU911054D0 (en) 1991-10-28
DK0448930T3 (da) 1994-06-20
ATE106240T1 (de) 1994-06-15
US5213810A (en) 1993-05-25
RO106191B1 (ro) 1993-03-31
EP0448930A1 (en) 1991-10-02
CN1063941C (zh) 2001-04-04
FI101676B1 (fi) 1998-08-14
EP0448930B1 (en) 1994-06-01
AU7397291A (en) 1991-10-03
NO300717B1 (no) 1997-07-14
IL97145A0 (en) 1992-05-25
PL167692B1 (en) 1995-10-31
PT97160B (pt) 1998-07-31
IL97145A (en) 1996-06-18

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910724

FG3A Patent granted, date of granting

Effective date: 19980420

PD3A Change of proprietorship

Free format text: WYETH HOLDINGS CORPORATION US

Effective date: 20031117

TE3A Change of address (patent)

Free format text: AMERICAN CYANAMID COMPANY US

Effective date: 20031117