PT92540A - Processo para a preparacao de derivados de anfotericina b - Google Patents

Processo para a preparacao de derivados de anfotericina b

Info

Publication number
PT92540A
PT92540A PT92540A PT9254089A PT92540A PT 92540 A PT92540 A PT 92540A PT 92540 A PT92540 A PT 92540A PT 9254089 A PT9254089 A PT 9254089A PT 92540 A PT92540 A PT 92540A
Authority
PT
Portugal
Prior art keywords
preparation
hydrogen
anfotericin
derivatives
ch2oh
Prior art date
Application number
PT92540A
Other languages
English (en)
Other versions
PT92540B (pt
Inventor
Michael John Driver
William Skinner Maclachlan
Andrew William Taylor
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT92540A publication Critical patent/PT92540A/pt
Publication of PT92540B publication Critical patent/PT92540B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Furan Compounds (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Peptides Or Proteins (AREA)
PT92540A 1988-12-19 1989-12-11 Processo para a preparacao de derivados de anfotericina b PT92540B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888829593A GB8829593D0 (en) 1988-12-19 1988-12-19 Novel compounds

Publications (2)

Publication Number Publication Date
PT92540A true PT92540A (pt) 1990-06-29
PT92540B PT92540B (pt) 1995-08-09

Family

ID=10648737

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92540A PT92540B (pt) 1988-12-19 1989-12-11 Processo para a preparacao de derivados de anfotericina b

Country Status (15)

Country Link
US (1) US5100876A (pt)
EP (1) EP0375222B1 (pt)
JP (1) JPH02207093A (pt)
KR (1) KR900009677A (pt)
AT (1) ATE119910T1 (pt)
AU (1) AU614204B2 (pt)
CA (1) CA2005134A1 (pt)
DE (1) DE68921719T2 (pt)
DK (1) DK624989A (pt)
ES (1) ES2071667T3 (pt)
GB (1) GB8829593D0 (pt)
IE (1) IE893956L (pt)
NZ (1) NZ231722A (pt)
PT (1) PT92540B (pt)
ZA (1) ZA899506B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
GB8829592D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
AU6951491A (en) * 1989-12-08 1991-07-18 Beecham Group Plc Amphotericin b derivatives, their production and use
GB9114949D0 (en) * 1991-07-11 1991-08-28 Smithkline Beecham Plc Novel compounds
FR2683723B1 (fr) * 1991-11-14 1995-05-19 Mayoly Spindler Laboratoires Nouveaux medicaments antiviraux actifs sur le virus vih.
GB9200713D0 (en) * 1992-01-14 1992-03-11 Smithkline Beecham Plc Novel compounds
CA2394833A1 (en) 2000-01-14 2001-07-19 Binh T. Dang Derivatives of polyene macrolides and preparation and use thereof
US9447136B2 (en) 2012-03-09 2016-09-20 Blirt S.A. Semisynthetic derivatives of Nystatin A1
KR20150027217A (ko) 2012-06-15 2015-03-11 블러트 에스.에이. 항진균성 항생 암포테리신 b의 n-치환된 제2 세대 유도체, 및 이의 제조 및 응용 방법
WO2015190587A1 (ja) * 2014-06-12 2015-12-17 塩野義製薬株式会社 ポリエンマクロライド誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2173632A1 (en) * 1971-02-04 1973-10-12 Le N Iss Purificn of amfotericin b - in dmf soln by adding water acidifying filtering adding water,making alkaline and washing
US4223130A (en) * 1978-09-28 1980-09-16 Schering Corporation Antibiotic 67-121, a polyene antifungal antibiotic produced by Actinoplanes caeruleus
US4235993A (en) * 1979-02-21 1980-11-25 E. R. Squibb & Sons, Inc. N-Benzylideneamphotericin B, its methyl ester and process for making water-soluble salts thereof
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
GB8829592D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
JPH02207093A (ja) 1990-08-16
ES2071667T3 (es) 1995-07-01
PT92540B (pt) 1995-08-09
EP0375222B1 (en) 1995-03-15
ATE119910T1 (de) 1995-04-15
DE68921719D1 (de) 1995-04-20
KR900009677A (ko) 1990-07-05
US5100876A (en) 1992-03-31
EP0375222A2 (en) 1990-06-27
EP0375222A3 (en) 1991-05-29
IE893956L (en) 1990-06-19
NZ231722A (en) 1992-04-28
DK624989D0 (da) 1989-12-11
ZA899506B (en) 1991-08-28
DK624989A (da) 1990-06-20
CA2005134A1 (en) 1990-06-19
AU4617089A (en) 1990-06-21
DE68921719T2 (de) 1995-07-13
AU614204B2 (en) 1991-08-22
GB8829593D0 (en) 1989-02-08

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950412

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961031