PT901460E - Processo para a preparacao de derivados do acido 5-amino-2,4,6-triiodo-1,3-benzenodicarboxilico - Google Patents

Processo para a preparacao de derivados do acido 5-amino-2,4,6-triiodo-1,3-benzenodicarboxilico

Info

Publication number
PT901460E
PT901460E PT97952841T PT97952841T PT901460E PT 901460 E PT901460 E PT 901460E PT 97952841 T PT97952841 T PT 97952841T PT 97952841 T PT97952841 T PT 97952841T PT 901460 E PT901460 E PT 901460E
Authority
PT
Portugal
Prior art keywords
benzenodycarboxylic
triodo
amino
preparation
acid derivatives
Prior art date
Application number
PT97952841T
Other languages
English (en)
Inventor
Nicola Desantis
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Publication of PT901460E publication Critical patent/PT901460E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT97952841T 1996-12-04 1997-12-01 Processo para a preparacao de derivados do acido 5-amino-2,4,6-triiodo-1,3-benzenodicarboxilico PT901460E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI002545A IT1286522B1 (it) 1996-12-04 1996-12-04 Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico

Publications (1)

Publication Number Publication Date
PT901460E true PT901460E (pt) 2003-01-31

Family

ID=11375347

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97952841T PT901460E (pt) 1996-12-04 1997-12-01 Processo para a preparacao de derivados do acido 5-amino-2,4,6-triiodo-1,3-benzenodicarboxilico

Country Status (12)

Country Link
EP (1) EP0901460B1 (pt)
JP (1) JP4219409B2 (pt)
AU (1) AU5657798A (pt)
CA (1) CA2244884A1 (pt)
DE (2) DE901460T1 (pt)
ES (1) ES2129384T3 (pt)
IN (1) IN185038B (pt)
IT (1) IT1286522B1 (pt)
NO (1) NO322067B1 (pt)
PT (1) PT901460E (pt)
WO (1) WO1998024757A1 (pt)
ZA (1) ZA9710862B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803485B2 (en) * 1999-02-26 2004-10-12 Bracco Imaging S.P.A. Process for the preparation of iopamidol
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
KR101098553B1 (ko) * 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법
AU2009317450B2 (en) * 2008-11-18 2015-05-07 Bracco Imaging Spa Process for the preparation of iodinated contrast agent
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
WO2014090650A1 (en) 2012-12-11 2014-06-19 Bracco Imaging Spa Continuous process for the preparation of (s)-2-acetyloxypropionic acid chloride
KR101520187B1 (ko) * 2013-10-25 2015-05-13 주식회사 대웅제약 이오프로마이드의 중간체의 제조방법
PL3066071T3 (pl) 2013-11-05 2018-09-28 Bracco Imaging S.P.A Sposób otrzymywania jopamidolu
BR112016027507B1 (pt) 2014-06-10 2020-11-24 Bracco Imaging Spa método para a preparação de ácido (s)-2-acetiloxipropiônico e seus derivados
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
US10836710B2 (en) 2016-12-05 2020-11-17 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
CN116354842A (zh) * 2021-12-20 2023-06-30 重庆圣华曦药业股份有限公司 一种改进的碘美普尔制备方法及其在制剂中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (pt) * 1974-12-13 1978-12-29 Savac Ag
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
CA2130829A1 (en) * 1992-02-28 1993-09-02 William Z. Mccarthy Synthesis of ioversol using a minimal excess of acetoxyacetylchloride

Also Published As

Publication number Publication date
IT1286522B1 (it) 1998-07-15
CA2244884A1 (en) 1998-06-11
NO322067B1 (no) 2006-08-07
NO983563D0 (no) 1998-08-03
EP0901460B1 (en) 2002-09-18
ES2129384T1 (es) 1999-06-16
WO1998024757A1 (en) 1998-06-11
DE69715616T2 (de) 2003-08-07
ITMI962545A0 (it) 1996-12-04
DE69715616D1 (de) 2002-10-24
AU5657798A (en) 1998-06-29
NO983563L (no) 1998-10-02
EP0901460A1 (en) 1999-03-17
ITMI962545A1 (it) 1998-06-04
JP4219409B2 (ja) 2009-02-04
IN185038B (pt) 2000-10-21
DE901460T1 (de) 1999-08-19
ES2129384T3 (es) 2003-04-01
JP2000505114A (ja) 2000-04-25
ZA9710862B (en) 1998-06-23

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