PT88990A - Processo para a preparacao de novos acidos aza-cicloalquil-alcano-difosfonicos - Google Patents

Processo para a preparacao de novos acidos aza-cicloalquil-alcano-difosfonicos

Info

Publication number
PT88990A
PT88990A PT88990A PT8899088A PT88990A PT 88990 A PT88990 A PT 88990A PT 88990 A PT88990 A PT 88990A PT 8899088 A PT8899088 A PT 8899088A PT 88990 A PT88990 A PT 88990A
Authority
PT
Portugal
Prior art keywords
diphosphones
cicloalquil
alcano
aza
preparation
Prior art date
Application number
PT88990A
Other languages
English (en)
Inventor
Knut A Jaeggi
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT88990A publication Critical patent/PT88990A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C07F9/5535—Seven-(or more) membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT88990A 1987-11-13 1988-11-11 Processo para a preparacao de novos acidos aza-cicloalquil-alcano-difosfonicos PT88990A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH443587 1987-11-13

Publications (1)

Publication Number Publication Date
PT88990A true PT88990A (pt) 1989-11-30

Family

ID=4276083

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88990A PT88990A (pt) 1987-11-13 1988-11-11 Processo para a preparacao de novos acidos aza-cicloalquil-alcano-difosfonicos

Country Status (6)

Country Link
US (1) US4929606A (pt)
EP (1) EP0317505A1 (pt)
JP (1) JPH01160993A (pt)
AU (1) AU2503688A (pt)
DK (1) DK632088A (pt)
PT (1) PT88990A (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4990503A (en) * 1988-08-12 1991-02-05 Yamanouchi Pharmaceutical Co., Ltd. Heterocyclic bisphosphonic acid derivatives
DE3843481A1 (de) * 1988-12-23 1990-06-28 Boehringer Ingelheim Kg Substituierte 3-azabicyclo/3.1.1/heptane, ihre herstellung und ihre verwendung
US5139786A (en) * 1989-07-07 1992-08-18 Ciba-Geigy Corporation Topical formulations
MX21452A (es) * 1989-07-07 1994-01-31 Ciba Geigy Ag Preparaciones farmaceuticas que se administran en forma topica.
EP0510066A4 (en) * 1990-01-12 1992-12-02 Rhone-Poulenc Rorer International (Holdings) Inc. 1-azetidyl and 1-hexamethylenimine alkyl or aryl bisphosphonic acids and their use as pharmacological agents
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
JPH06298779A (ja) * 1993-04-15 1994-10-25 Hoechst Japan Ltd ヘテロ環イミノビスメチレンビスホスホン酸誘導体
US5854227A (en) * 1994-03-04 1998-12-29 Hartmann; John F. Therapeutic derivatives of diphosphonates
CA2321864A1 (en) * 1998-12-25 2000-07-06 Toray Industries, Inc. Interleukin-6 production inhibitor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3733270A (en) * 1971-03-08 1973-05-15 Monsanto Co Methods of scale inhibition
JPS54135724A (en) * 1978-04-11 1979-10-22 Nissan Chem Ind Ltd Preparation of amino-methylenedisulfonic acid derivative
SU1002300A1 (ru) * 1981-10-29 1983-03-07 Ордена Ленина институт элементоорганических соединений им.А.Н.Несмеянова Способ получени @ -аминозамещенных- @ -оксипропилидендифосфоновых кислот
DE3203308A1 (de) * 1982-01-27 1983-07-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate
DE3232997A1 (de) * 1982-09-04 1984-03-08 Henkel KGaA, 4000 Düsseldorf Diphosphonsaeuren
DE3428524A1 (de) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3626058A1 (de) * 1986-08-01 1988-02-11 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
EP0272208B1 (de) * 1986-11-21 1991-06-12 Ciba-Geigy Ag Aromatisch substituierte Azacyclo-alkylalkandiphosphonsäuren

Also Published As

Publication number Publication date
AU2503688A (en) 1989-05-25
EP0317505A1 (de) 1989-05-24
US4929606A (en) 1990-05-29
DK632088A (da) 1989-05-14
JPH01160993A (ja) 1989-06-23
DK632088D0 (da) 1988-11-11

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Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19921126