PT88431A - Process for the preparation of 4-oxo-3-quinolinecarboxylic acids useful as antibacterial agents - Google Patents

Process for the preparation of 4-oxo-3-quinolinecarboxylic acids useful as antibacterial agents

Info

Publication number
PT88431A
PT88431A PT88431A PT8843188A PT88431A PT 88431 A PT88431 A PT 88431A PT 88431 A PT88431 A PT 88431A PT 8843188 A PT8843188 A PT 8843188A PT 88431 A PT88431 A PT 88431A
Authority
PT
Portugal
Prior art keywords
oxo
preparation
antibacterial agents
acids useful
quinolinecarboxylic acids
Prior art date
Application number
PT88431A
Other languages
English (en)
Other versions
PT88431B (pt
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of PT88431A publication Critical patent/PT88431A/pt
Publication of PT88431B publication Critical patent/PT88431B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
PT88431A 1987-09-08 1988-09-06 Processo para a preparacao de acidos 4-oxo-3-quinolinocarboxilicos uteis coma agentes anti-bacterianos PT88431B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9435987A 1987-09-08 1987-09-08

Publications (2)

Publication Number Publication Date
PT88431A true PT88431A (pt) 1989-07-31
PT88431B PT88431B (pt) 1992-10-30

Family

ID=22244685

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88431A PT88431B (pt) 1987-09-08 1988-09-06 Processo para a preparacao de acidos 4-oxo-3-quinolinocarboxilicos uteis coma agentes anti-bacterianos

Country Status (15)

Country Link
EP (1) EP0309789A1 (pt)
JP (1) JPH01100166A (pt)
KR (1) KR890005083A (pt)
AR (1) AR247553A1 (pt)
AU (1) AU598394B2 (pt)
DK (1) DK493988A (pt)
FI (1) FI884106A (pt)
IL (1) IL87569A (pt)
MX (1) MX12881A (pt)
MY (1) MY103910A (pt)
NO (1) NO170930C (pt)
NZ (1) NZ225926A (pt)
PH (1) PH26759A (pt)
PT (1) PT88431B (pt)
ZA (1) ZA886400B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075319A (en) * 1987-09-08 1991-12-24 Sterling Drug Inc. Pyridinyl-quinolone compounds, their preparation and use
US5169853A (en) * 1987-09-08 1992-12-08 Sterling Drug Inc. Pyridinyl-quinolone compounds, their preparation and use
US4996355A (en) * 1989-04-14 1991-02-26 Mallinckrodt, Inc. Novel intermediates for the production of 2,4,5-trifluorobenzoyl fluoride
CA2078444A1 (en) 1990-04-18 1991-10-19 Thomas P. Demuth, Jr. Antimicrobial quinolonyl lactams
CN1338455A (zh) * 2000-08-16 2002-03-06 大连绿源实业有限公司 新的喹诺酮羧酸的制备方法
WO2010058421A2 (en) * 2008-11-18 2010-05-27 Aditya Birla Science & Technology Co. Ltd. A process for synthesis of 2, 4-dichloro-5- fluoroacetophenone (dcfa)
CN107686456B (zh) * 2017-07-25 2018-10-23 杭州师范大学 一种喹喏酮关键中间体乙酯胺化物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753993A (en) * 1971-05-17 1973-08-21 Sterling Drug Inc 1,4-dihydro-4-oxo-7-pyridyl-3-quinoline-carboxylic acid derivatives
US3907808A (en) * 1971-05-17 1975-09-23 Sterling Drug Inc 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
US4529725A (en) * 1984-04-26 1985-07-16 Abbott Laboratories 1-Pyridine substituted quino-benzothiazine
EP0179239A3 (en) * 1984-09-17 1986-08-13 Sterling Drug Inc. 7-(pyridinyl)-/-alkyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid having antibacterial activity and preparation thereof
US4636506A (en) * 1984-12-06 1987-01-13 Pfizer, Inc. 7-heterocyclic-1,4-dihydroquinolones

Also Published As

Publication number Publication date
EP0309789A1 (en) 1989-04-05
NZ225926A (en) 1990-04-26
NO170930B (no) 1992-09-21
MX12881A (es) 1993-08-01
DK493988A (da) 1989-03-09
KR890005083A (ko) 1989-05-11
NO883897D0 (no) 1988-09-01
FI884106A0 (fi) 1988-09-06
PH26759A (en) 1992-09-28
AR247553A1 (es) 1995-01-31
AU598394B2 (en) 1990-06-21
JPH01100166A (ja) 1989-04-18
NO170930C (no) 1992-12-30
IL87569A0 (en) 1989-01-31
AU2184388A (en) 1989-03-09
PT88431B (pt) 1992-10-30
FI884106A (fi) 1989-03-09
IL87569A (en) 1992-08-18
ZA886400B (en) 1989-04-26
MY103910A (en) 1993-10-30
NO883897L (no) 1989-03-09
DK493988D0 (da) 1988-09-06

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920410

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941031