PT87051A - Process for preparing indane sulphonamide antiarrhythmic agents - Google Patents

Process for preparing indane sulphonamide antiarrhythmic agents

Info

Publication number
PT87051A
PT87051A PT87051A PT8705188A PT87051A PT 87051 A PT87051 A PT 87051A PT 87051 A PT87051 A PT 87051A PT 8705188 A PT8705188 A PT 8705188A PT 87051 A PT87051 A PT 87051A
Authority
PT
Portugal
Prior art keywords
sulphonamide
antiarrhythmic agents
indane
preparing
alkyl
Prior art date
Application number
PT87051A
Other languages
English (en)
Other versions
PT87051B (pt
Inventor
Peter Edward Cross
John Edmund Arrowsmith
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of PT87051A publication Critical patent/PT87051A/pt
Publication of PT87051B publication Critical patent/PT87051B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
PT87051A 1987-03-25 1988-03-23 Processo para a preparacao de agentes anti-arritmicos de indano-sulfonamidas PT87051B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878707123A GB8707123D0 (en) 1987-03-25 1987-03-25 Antiarrhythmic agents

Publications (2)

Publication Number Publication Date
PT87051A true PT87051A (pt) 1988-04-01
PT87051B PT87051B (pt) 1992-07-31

Family

ID=10614609

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87051A PT87051B (pt) 1987-03-25 1988-03-23 Processo para a preparacao de agentes anti-arritmicos de indano-sulfonamidas

Country Status (12)

Country Link
US (1) US5006561A (pt)
EP (1) EP0286278B1 (pt)
JP (1) JPS63264556A (pt)
AT (1) ATE59842T1 (pt)
AU (1) AU593739B2 (pt)
DE (1) DE3861484D1 (pt)
DK (1) DK160788A (pt)
ES (1) ES2036674T3 (pt)
GB (1) GB8707123D0 (pt)
GR (1) GR3001665T3 (pt)
IE (1) IE61071B1 (pt)
PT (1) PT87051B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
JP2931986B2 (ja) * 1989-02-17 1999-08-09 武田薬品工業株式会社 アラルキルアミン誘導体
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
EP0507863A4 (en) * 1989-12-28 1993-07-07 Virginia Commonwealth University Sigma receptor ligands and the use thereof
US6087346A (en) * 1993-06-23 2000-07-11 Cambridge Neuroscience, Inc. Sigma receptor ligands and the use thereof
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5475139A (en) * 1993-10-22 1995-12-12 Yung Shin Pharm. Ind. Co., Ltd. Method for the preparation of substituted derivatives of diphenyl amine
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
FR2717175B1 (fr) * 1994-03-11 1996-06-14 Adir Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
US6083986A (en) * 1996-07-26 2000-07-04 Icagen, Inc. Potassium channel inhibitors
US6333337B1 (en) 1998-01-27 2001-12-25 Icagen, Inc. Potassium channel inhibitors
US6632836B1 (en) 1998-10-30 2003-10-14 Merck & Co., Inc. Carbocyclic potassium channel inhibitors
US6303637B1 (en) 1998-10-30 2001-10-16 Merck & Co., Inc. Heterocyclic potassium channel inhibitors
GB9913083D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds
CA2393756A1 (en) 1999-12-21 2001-06-28 Aimee D. Reed Potassium channel inhibitors
CA2405611A1 (en) * 2000-05-04 2001-11-08 Warner-Lambert Company Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
US6566380B2 (en) 2000-07-25 2003-05-20 Icagen, Inc. Potassium channel inhibitors
US6620849B2 (en) 2000-07-26 2003-09-16 Icafen, Inc. Potassium channel inhibitors
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518652A1 (de) * 1965-05-29 1969-04-10 Albert Ag Chem Werke Verfahren zur Herstellung von pharmazeutisch wirksamen Derivaten des 2-Aminoindans
US3923813A (en) * 1969-12-19 1975-12-02 Christiaens Sa A Derivatives of 2-aminoindanes
DE3566886D1 (en) * 1984-05-04 1989-01-26 Upjohn Co N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use
US4959500A (en) * 1989-05-23 1990-09-25 Ethyl Corporation Polybrominated bis sulfonamides

Also Published As

Publication number Publication date
EP0286278B1 (en) 1991-01-09
AU593739B2 (en) 1990-02-15
ATE59842T1 (de) 1991-01-15
DE3861484D1 (de) 1991-02-14
PT87051B (pt) 1992-07-31
DK160788D0 (da) 1988-03-24
JPS63264556A (ja) 1988-11-01
DK160788A (da) 1988-12-22
IE61071B1 (en) 1994-09-21
ES2036674T3 (es) 1993-06-01
JPH0480019B2 (pt) 1992-12-17
IE880887L (en) 1988-09-25
GR3001665T3 (en) 1992-11-23
US5006561A (en) 1991-04-09
EP0286278A1 (en) 1988-10-12
AU1642488A (en) 1989-11-23
GB8707123D0 (en) 1987-04-29

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920103

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960731