PT863125E - Processo para a preparacao de esteres de acido 3-hidroxioctanoico enanteomericamente puros atraves de hidrogenacao catalitica assimetrica - Google Patents

Processo para a preparacao de esteres de acido 3-hidroxioctanoico enanteomericamente puros atraves de hidrogenacao catalitica assimetrica

Info

Publication number
PT863125E
PT863125E PT98103245T PT98103245T PT863125E PT 863125 E PT863125 E PT 863125E PT 98103245 T PT98103245 T PT 98103245T PT 98103245 T PT98103245 T PT 98103245T PT 863125 E PT863125 E PT 863125E
Authority
PT
Portugal
Prior art keywords
preparation
hydrogenacao
enanteomericamente
catalitica
asimetrica
Prior art date
Application number
PT98103245T
Other languages
English (en)
Inventor
Rainer Gewald
Gunter Laban
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of PT863125E publication Critical patent/PT863125E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/04Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PT98103245T 1997-03-06 1998-02-25 Processo para a preparacao de esteres de acido 3-hidroxioctanoico enanteomericamente puros atraves de hidrogenacao catalitica assimetrica PT863125E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19709069A DE19709069C2 (de) 1997-03-06 1997-03-06 Enantiomerenreine 3-Hydroxyoctandisäurediester, Verfahren zur Herstellung derselben durch asymmetrische katalytische Hydrierung sowie Verfahren zur Herstellung von R-(+)- und S-(-)-alpha-Liponsäure

Publications (1)

Publication Number Publication Date
PT863125E true PT863125E (pt) 2002-05-31

Family

ID=7822377

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98103245T PT863125E (pt) 1997-03-06 1998-02-25 Processo para a preparacao de esteres de acido 3-hidroxioctanoico enanteomericamente puros atraves de hidrogenacao catalitica assimetrica

Country Status (9)

Country Link
US (2) US6013833A (pt)
EP (1) EP0863125B1 (pt)
JP (1) JPH10273476A (pt)
AT (1) ATE209623T1 (pt)
CA (1) CA2231093C (pt)
DE (2) DE19709069C2 (pt)
DK (1) DK0863125T3 (pt)
ES (1) ES2167817T3 (pt)
PT (1) PT863125E (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19845517A1 (de) * 1998-10-02 2000-04-06 Basf Ag Verfahren zur asymmetrische Hydrierung von beta-Ketoestern
DE10036516A1 (de) * 2000-07-27 2002-02-07 Asta Medica Ag Verfahren zur Herstellung von enantiomerenreinen 6,8-Dihydroxyoctansäureestern durch assymetrische katalytische Hydrierung
DE10137381A1 (de) 2001-07-31 2003-02-13 Viatris Gmbh Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung
DE10160149A1 (de) * 2001-12-07 2003-06-18 Basf Ag Verfahren zur Herstellung von Dihydroxycarbonsäureestern in Abwesenheit von Lösungsmitteln
DE10201464B4 (de) 2002-01-16 2005-06-16 Viatris Gmbh & Co. Kg Verfahren zur Herstellung reiner Thioctsäure

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883580A (en) * 1972-02-09 1975-05-13 Monsanto Co Asymmetric reduction of ketones to form optically active alcohols
DE3629116A1 (de) * 1986-08-27 1988-03-10 Asta Pharma Ag Verfahren zur herstellung enantiomerenreiner r-(+)-(alpha)-liponsaeure und s-(-)-(alpha)-liponsaeure (thioctsaeure) sowie nonen- beziehungsweise mesylderivate als zwischenprodukte hierfuer
JPH0699367B2 (ja) * 1987-06-11 1994-12-07 高砂香料工業株式会社 光学活性アルコ−ルの製法
JPH064543B2 (ja) * 1987-06-18 1994-01-19 高砂香料工業株式会社 光学活性アルコ−ルの製造法
DE4037440A1 (de) * 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
US5508435A (en) * 1992-07-29 1996-04-16 Merck & Co., Inc. Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- or gamma-ketoamides

Also Published As

Publication number Publication date
EP0863125B1 (de) 2001-11-28
US6013833A (en) 2000-01-11
JPH10273476A (ja) 1998-10-13
DK0863125T3 (da) 2002-02-25
US6229042B1 (en) 2001-05-08
ATE209623T1 (de) 2001-12-15
DE19709069C2 (de) 2000-04-06
ES2167817T3 (es) 2002-05-16
EP0863125A1 (de) 1998-09-09
DE19709069A1 (de) 1998-09-17
CA2231093A1 (en) 1998-09-06
CA2231093C (en) 2007-01-02
DE59802194D1 (de) 2002-01-10

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