PT832886E - Derivados de flavonas processo para a sua preparacao e as composicoes farmaceuticas que os contem - Google Patents
Derivados de flavonas processo para a sua preparacao e as composicoes farmaceuticas que os contemInfo
- Publication number
- PT832886E PT832886E PT97402202T PT97402202T PT832886E PT 832886 E PT832886 E PT 832886E PT 97402202 T PT97402202 T PT 97402202T PT 97402202 T PT97402202 T PT 97402202T PT 832886 E PT832886 E PT 832886E
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- optionally substituted
- alkoxy
- optionally
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9611808A FR2753969B1 (fr) | 1996-09-27 | 1996-09-27 | Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
PT832886E true PT832886E (pt) | 2003-03-31 |
Family
ID=9496129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97402202T PT832886E (pt) | 1996-09-27 | 1997-09-23 | Derivados de flavonas processo para a sua preparacao e as composicoes farmaceuticas que os contem |
Country Status (18)
Country | Link |
---|---|
US (1) | US5889003A (pt) |
EP (1) | EP0832886B1 (pt) |
JP (1) | JPH10114766A (pt) |
CN (1) | CN1094936C (pt) |
AT (1) | ATE227712T1 (pt) |
AU (1) | AU728990B2 (pt) |
BR (1) | BR9704900A (pt) |
CA (1) | CA2216617C (pt) |
DE (1) | DE69717044T2 (pt) |
DK (1) | DK0832886T3 (pt) |
ES (1) | ES2187738T3 (pt) |
FR (1) | FR2753969B1 (pt) |
HU (1) | HUP9701588A3 (pt) |
NO (1) | NO974455L (pt) |
NZ (1) | NZ328858A (pt) |
PL (1) | PL322297A1 (pt) |
PT (1) | PT832886E (pt) |
ZA (1) | ZA978652B (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997011692A2 (en) * | 1995-09-11 | 1997-04-03 | Osteoarthritis Sciences, Inc. | Protein tyrosine kinase inhibitors for treating osteoarthritis |
PL346271A1 (en) | 1998-08-26 | 2002-01-28 | Smithkline Beecham Corp | Therapies for treating pulmonary diseases |
KR20010079922A (ko) * | 1998-09-24 | 2001-08-22 | 미우라 아키라 | 하이드록시플라본 유도체 |
MXPA02001830A (es) | 1999-08-21 | 2002-08-12 | Byk Gulden Lomberg Chem Fab | Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor. |
US6806257B1 (en) | 1999-10-20 | 2004-10-19 | Board Of Trustees Of Southern Illinois University | Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators |
US6334998B1 (en) * | 1999-12-07 | 2002-01-01 | Parker Hughes Institute | Estrogens for treating ALS |
EP1127572A3 (en) * | 2000-02-25 | 2003-05-02 | Basf Aktiengesellschaft | Use of flavones for treating cycloxygenase-2 mediated diseases |
US6472436B1 (en) * | 2000-07-17 | 2002-10-29 | The Salk Institute For Biological Studies | Methods for protecting cells from amyloid toxicity and for inhibiting amyloid protein production |
DE10104350A1 (de) * | 2001-02-01 | 2002-08-14 | Merck Patent Gmbh | Verfahren zur Herstellung von Flavon Derivaten |
DE10232595A1 (de) * | 2002-07-18 | 2004-02-05 | Merck Patent Gmbh | Lichtschutzmittel |
EA200501548A1 (ru) | 2003-04-01 | 2006-02-24 | Апплайд Резеч Системз Арс Холдинг Н.В. | Ингибиторы фосфодиэстераз при бесплодии |
JP5058481B2 (ja) * | 2005-11-28 | 2012-10-24 | 丸善製薬株式会社 | 角化細胞増殖剤、サイクリックampホスホジエステラーゼ阻害剤、及び保湿剤 |
US20100056791A1 (en) * | 2006-09-01 | 2010-03-04 | Yasushi Kohno | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same |
CN101148444A (zh) * | 2006-09-20 | 2008-03-26 | 上海特化医药科技有限公司 | 黄酮衍生物、制备方法及应用 |
KR100930467B1 (ko) | 2007-06-07 | 2009-12-08 | 동아제약주식회사 | 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도 |
JP4559531B1 (ja) * | 2009-12-03 | 2010-10-06 | ウシオケミックス株式会社 | ノビレチンの製造方法 |
CN103059005B (zh) * | 2012-11-22 | 2015-04-22 | 中南民族大学 | 白杨素酰胺衍生物及其医药用途 |
CN105906598B (zh) * | 2016-05-19 | 2018-05-08 | 江苏耐雀生物工程技术有限公司 | 白杨素衍生物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2623808B1 (fr) * | 1987-12-01 | 1990-03-09 | Adir | Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
FR2689127B1 (fr) * | 1992-03-31 | 1994-05-06 | Adir Cie | Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
FR2748025B1 (fr) * | 1996-04-25 | 1998-10-30 | Adir | Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant |
-
1996
- 1996-09-27 FR FR9611808A patent/FR2753969B1/fr not_active Expired - Fee Related
-
1997
- 1997-09-23 EP EP97402202A patent/EP0832886B1/fr not_active Expired - Lifetime
- 1997-09-23 DE DE69717044T patent/DE69717044T2/de not_active Expired - Fee Related
- 1997-09-23 DK DK97402202T patent/DK0832886T3/da active
- 1997-09-23 PT PT97402202T patent/PT832886E/pt unknown
- 1997-09-23 ES ES97402202T patent/ES2187738T3/es not_active Expired - Lifetime
- 1997-09-23 AT AT97402202T patent/ATE227712T1/de not_active IP Right Cessation
- 1997-09-25 PL PL97322297A patent/PL322297A1/xx unknown
- 1997-09-26 NZ NZ328858A patent/NZ328858A/en unknown
- 1997-09-26 BR BR9704900A patent/BR9704900A/pt not_active IP Right Cessation
- 1997-09-26 ZA ZA9708652A patent/ZA978652B/xx unknown
- 1997-09-26 CA CA002216617A patent/CA2216617C/fr not_active Expired - Fee Related
- 1997-09-26 AU AU39271/97A patent/AU728990B2/en not_active Ceased
- 1997-09-26 JP JP9261323A patent/JPH10114766A/ja active Pending
- 1997-09-26 US US08/968,837 patent/US5889003A/en not_active Expired - Fee Related
- 1997-09-26 NO NO974455A patent/NO974455L/no not_active Application Discontinuation
- 1997-09-26 HU HU9701588A patent/HUP9701588A3/hu unknown
- 1997-09-26 CN CN97120535A patent/CN1094936C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1094936C (zh) | 2002-11-27 |
DE69717044T2 (de) | 2003-07-24 |
EP0832886A1 (fr) | 1998-04-01 |
CA2216617C (fr) | 2002-12-03 |
DE69717044D1 (de) | 2002-12-19 |
HUP9701588A2 (hu) | 1998-12-28 |
HU9701588D0 (en) | 1997-11-28 |
FR2753969A1 (fr) | 1998-04-03 |
NO974455D0 (no) | 1997-09-26 |
DK0832886T3 (da) | 2003-03-10 |
FR2753969B1 (fr) | 1998-10-30 |
PL322297A1 (en) | 1998-03-30 |
ZA978652B (en) | 1998-03-27 |
AU728990B2 (en) | 2001-01-25 |
ATE227712T1 (de) | 2002-11-15 |
AU3927197A (en) | 1998-04-02 |
NO974455L (no) | 1998-03-30 |
CN1179422A (zh) | 1998-04-22 |
CA2216617A1 (fr) | 1998-03-27 |
US5889003A (en) | 1999-03-30 |
JPH10114766A (ja) | 1998-05-06 |
NZ328858A (en) | 1998-01-26 |
EP0832886B1 (fr) | 2002-11-13 |
BR9704900A (pt) | 1998-10-27 |
HUP9701588A3 (en) | 1999-03-01 |
ES2187738T3 (es) | 2003-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT832886E (pt) | Derivados de flavonas processo para a sua preparacao e as composicoes farmaceuticas que os contem | |
BR9908764A (pt) | Composto e seus sais farmaceuticamente aceitáveis ou ésteres hidrolisáveis in vivo, uso destes, processo para prepará-los, e, composição farmacêutica | |
DE69918404D1 (de) | Aminophenoxyessigsäure derivate als neuroschützende mittel | |
BR9302643A (pt) | Compostos,seu processo de preparacao,seu uso e composicao farmaceutica | |
PT652868E (pt) | Inibidores da fosfodiesterase do amp ciclico | |
ATE163919T1 (de) | Naphthalen-derivate mit affinität für melatonin- rezeptoren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen | |
EA200401053A1 (ru) | Оксо-азабициклические соединения | |
PT81855B (pt) | Processo de preparacao de arilciclobutilalquilaminas e de composicoes farmaceuticas que as contem | |
PT96368A (pt) | Processo para a preparacao de derivados heterociclicos, contendo um anel de cinco membros com pelo menos um atomo de azoto | |
ES2108772T3 (es) | Derivados de aminofosfonato substituidos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. | |
DK84181A (da) | Derivater af 3,4,5-trihydroxypiperidin,fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler samt til dyreernaering | |
KR860005794A (ko) | 이미다졸 유도체의 제조방법 | |
AR002041A1 (es) | Nuevos taxoides, procedimiento para prepararlos, los compuestos intermediarios de aplicacion con dicho procedimiento, procedimiento parapreparar dichos intermediarios y las composiciones farmaceuticas que contienen dichos taxoides. | |
BR9911300A (pt) | Composto, composição farmacêutica, e, uso do composto | |
BR0004823A (pt) | Compostos policìclicos de azaindol, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos | |
ES2172294T3 (es) | Nuevos derivados del 1-indanol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
DK0541263T3 (da) | 5-Piperazinylalkyl-1,5-benzothiazepinoner, der er nyttige som calciumantagonister | |
SE8007025L (sv) | Derivat av 1,2,4-oxadiazolin-5-on, sett for deras framstellning och farmaceutiska beredningar innehallande dem | |
NO304314B1 (no) | Cykloheksanderivater og anvendelse av forbindelsene for fremstilling av legemidler | |
SE8503225L (sv) | Diacyloxi-1,8-acyl-10-antroner, sett for deras framstellning och deras anvendning som lekemedel for djur och menniska samt for kosmetika | |
BR9912885A (pt) | Derivado de 3-azabiciclo-[3.2.0]- heptano n-substituìdo | |
PT93904A (pt) | Processo para a preparacao de novos derivados benzotiazolinonicos e de composicoes farmaceuticas que os contem | |
DE59606328D1 (de) | Verfahren zur Herstellung von gegebenenfalls 2-substituierten 5-Chlor-imidazol-4-carbaldehyden | |
SE8105139L (sv) | Karbamatderivat, insekticida, miticida eller nematocida kompositioner innehallande dessa samt forfarande for framstellning derav | |
BR0208719A (pt) | Uso de um composto |