PT784486E - Inerleucina-12 como um adjuvante para vacinas contra paramyxoviridae - Google Patents

Inerleucina-12 como um adjuvante para vacinas contra paramyxoviridae

Info

Publication number: PT784486E
Authority: PT; Portugal
Prior art keywords: virus; paramyxoviridae family; parainfluenza; inerleukin; adjuvant
Prior art date: 1994-10-05

Application number

PT95938133T

Other languages

English (en)

Inventor

Barney S Graham

Tang Yi-Wei

Original Assignee

Univ Vanderbilt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-05

Filing date

1995-10-02

Publication date

2006-07-31

1995-10-02 Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt

2006-07-31 Publication of PT784486E publication Critical patent/PT784486E/pt

Links

241000711504 Paramyxoviridae Species 0.000 title abstract 5
239000002671 adjuvant Substances 0.000 title abstract 3
229960005486 vaccine Drugs 0.000 title 1
241000700605 Viruses Species 0.000 abstract 10
102000013462 Interleukin-12 Human genes 0.000 abstract 4
108010065805 Interleukin-12 Proteins 0.000 abstract 4
208000002606 Paramyxoviridae Infections Diseases 0.000 abstract 4
229940117681 interleukin-12 Drugs 0.000 abstract 4
239000000427 antigen Substances 0.000 abstract 2
102000036639 antigens Human genes 0.000 abstract 2
108091007433 antigens Proteins 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
241000711404 Avian avulavirus 1 Species 0.000 abstract 1
241000711895 Bovine orthopneumovirus Species 0.000 abstract 1
241000712083 Canine morbillivirus Species 0.000 abstract 1
241000712079 Measles morbillivirus Species 0.000 abstract 1
241000712045 Morbillivirus Species 0.000 abstract 1
241000711902 Pneumovirus Species 0.000 abstract 1
241000725643 Respiratory syncytial virus Species 0.000 abstract 1
230000029812 viral genome replication Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Organic Chemistry (AREA)
Pulmonology (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

PT95938133T 1994-10-05 1995-10-02 Inerleucina-12 como um adjuvante para vacinas contra paramyxoviridae PT784486E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US31848094A	1994-10-05	1994-10-05

Publications (1)

Publication Number	Publication Date
PT784486E true PT784486E (pt)	2006-07-31

Family

ID=23238354

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95938133T PT784486E (pt)	1994-10-05	1995-10-02	Inerleucina-12 como um adjuvante para vacinas contra paramyxoviridae

Country Status (11)

Country	Link
US (2)	US6071893A (pt)
EP (1)	EP0784486B1 (pt)
JP (1)	JP3939752B2 (pt)
AT (1)	ATE322289T1 (pt)
AU (1)	AU701753B2 (pt)
DE (1)	DE69534922T2 (pt)
DK (1)	DK0784486T3 (pt)
ES (1)	ES2257744T3 (pt)
MX (1)	MX9702396A (pt)
PT (1)	PT784486E (pt)
WO (1)	WO1996011019A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2262181T3 (es) *	1996-05-31	2006-11-16	National University Of Ireland, Maynooth	Il-12 como adyuvante en la vacuna contra la especie bordetella pertussis.
GB9712347D0 (en) *	1997-06-14	1997-08-13	Smithkline Beecham Biolog	Vaccine
BR9907885A (pt) *	1998-02-12	2000-11-14	American Cyanamid Co	Composição de vacina, processo para fazer surgir uma resposta imune a um antìgeno de vìrus sincicial respiratório, e, composição imunogênica
IL137809A0 (en) *	1998-02-12	2001-10-31	American Cyanamid Co	Pneumococcal and meningococcal vaccines formulated with interleukin-12
US6814968B1 (en)	1998-06-04	2004-11-09	Vanderbilt University	Inhibition of viral infection and spread with viral and RhoA-derived peptides
ID30407A (id)	1999-05-13	2001-11-29	American Cyanamid Co	Formulasi-formulasi kombinasi bahan penambah
CN1437481A (zh)	2000-06-22	2003-08-20	美国氰胺公司	作为佐剂组合的qs－21和il－12
SK5482003A3 (en) *	2000-11-10	2004-03-02	Wyeth Corp	Adjuvant combination formulations
US20030129161A1 (en) *	2001-09-17	2003-07-10	Hsien-Jue Chu	Interleukin-12 as a veterinary vaccine adjuvant
US20090227025A1 (en) *	2003-06-06	2009-09-10	The Board Of Regents Of The University Of Texas System	Ex vivo human lung/immune system model using tissue engineering for studying microbial pathogens with lung tropism
CN113304158B (zh) *	2021-06-10	2022-10-28	山东省农业科学院畜牧兽医研究所	磺胺甲氧吡嗪在制备预防和/或治疗牛副流感病毒产品中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5223254A (en) *	1987-09-29	1993-06-29	Praxis Biologics, Inc.	Respiratory syncytial virus: vaccines
GB8914968D0 (en) *	1989-06-29	1989-08-23	Connaught Lab	Production of virus and purification of viral envelope proteins for vaccine use
TW275632B (pt) *	1992-04-21	1996-05-11	American Cyanamid Co
EP0604727A1 (en) *	1992-12-31	1994-07-06	American Cyanamid Company	Improved immunogenicity of a vaccine by incorporation of a cytokine within an immune-stimulating complex containing an antigen
DK0705109T4 (da) *	1993-05-25	2004-05-10	Wyeth Corp	Adjuvanser til vacciner mod respiratorisk syncytialvirus
US5830463A (en) *	1993-07-07	1998-11-03	University Technology Corporation	Yeast-based delivery vehicles
US7223410B1 (en) *	1994-08-05	2007-05-29	Sanofi Pasteur Limited	Inactivated respiratory syncytial viral vaccines
US5571515A (en) *	1994-04-18	1996-11-05	The Wistar Institute Of Anatomy & Biology	Compositions and methods for use of IL-12 as an adjuvant
SI0759780T1 (en) *	1994-05-10	2000-12-31	American Home Products Corporation	Improved modified live brsv vaccine

1995
- 1995-10-02 DK DK95938133T patent/DK0784486T3/da active
- 1995-10-02 MX MX9702396A patent/MX9702396A/es not_active IP Right Cessation
- 1995-10-02 AT AT95938133T patent/ATE322289T1/de not_active IP Right Cessation
- 1995-10-02 WO PCT/US1995/012656 patent/WO1996011019A1/en active IP Right Grant
- 1995-10-02 PT PT95938133T patent/PT784486E/pt unknown
- 1995-10-02 AU AU38876/95A patent/AU701753B2/en not_active Ceased
- 1995-10-02 EP EP95938133A patent/EP0784486B1/en not_active Expired - Lifetime
- 1995-10-02 ES ES95938133T patent/ES2257744T3/es not_active Expired - Lifetime
- 1995-10-02 JP JP51263596A patent/JP3939752B2/ja not_active Expired - Fee Related
- 1995-10-02 DE DE69534922T patent/DE69534922T2/de not_active Expired - Lifetime
1997
- 1997-11-26 US US08/980,160 patent/US6071893A/en not_active Expired - Fee Related
2006
- 2006-12-01 US US11/607,073 patent/US20070087016A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DK0784486T3 (da)	2006-08-14
WO1996011019A1 (en)	1996-04-18
MX9702396A (es)	1997-12-31
ATE322289T1 (de)	2006-04-15
ES2257744T3 (es)	2006-08-01
DE69534922T2 (de)	2006-11-23
DE69534922D1 (en)	2006-05-18
AU701753B2 (en)	1999-02-04
EP0784486A1 (en)	1997-07-23
JPH10507175A (ja)	1998-07-14
US6071893A (en)	2000-06-06
EP0784486B1 (en)	2006-04-05
JP3939752B2 (ja)	2007-07-04
AU3887695A (en)	1996-05-02
US20070087016A1 (en)	2007-04-19

Publication	Publication Date	Title
PT784486E (pt)	2006-07-31	Inerleucina-12 como um adjuvante para vacinas contra paramyxoviridae
HRP20050192B1 (hr)	2014-02-14	Cjepivo za infekcije dišnog i spolnog sustava kod goveda
DE69628834D1 (de)	2003-07-31	Virus impfstoff
AU711350B2 (en)	1999-10-14	Improved modified live BRSV vaccine
RU2400248C2 (ru)	2010-09-27	ПОЛИВАЛЕНТНЫЕ ВАКЦИНЫ ДЛЯ СОБАК ПРОТИВ Leptospira bratislava И ДРУГИХ ПАТОГЕНОВ
SI2762163T1 (en)	2018-05-31	Procedures for administration of the vaccine
RU2005128790A (ru)	2006-06-10	Модифицированные живые вакцины, содержащие вирус бычьего герпеса типа 1 (bhv-1(ibr)) и/или вирус бычьей вирусной диареи (bvdv), для беременных и вскармливаемых особей скота
AR042935A1 (es)	2005-07-06	Vacunas caninas contra bordetella bronchiseptica
Prince et al.	2003	Immunoprotective Activity and Safety of a RespiratorySyncytial Virus Vaccine: Mucosal Delivery of Fusion Glycoprotein with aCpG OligodeoxynucleotideAdjuvant
RU2006133328A (ru)	2008-03-27	Способ вакцинации против инфекции семенников bvdv
Edwards et al.	1986	Evidence for an immunocompromising effect of bovine pestivirus on bovid herpesvirus 1 vaccination
OTTOLINI et al.	2000	Enhanced pulmonary pathology in cotton rats upon challenge after immunization with inactivated parainfluenza virus 3 vaccines
AR016987A1 (es)	2001-08-01	Composiciones acuosas de vacuna acuosaa para la profilaxis de hepatitis b o hepatitis b/a
ZIOLA et al.	1987	T cell cross-reactivity among viruses of the paramyxoviridae
GB1059095A (en)	1967-02-15	Interferential vaccines
Panigrahi et al.	1987	Structural proteins of bovine parainfluenza-3 virus
Beale	1974	Measles vaccines
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Basaraba	1991	Mechanisms of in vitro immunosuppression by bovine parainfluenza virus type 3
WO2002011761A2 (en)	2002-02-14	Vaccine against rsv
Bahri et al.	1998	Protective antibody titre against Newcastle disease in ostriches (Struthio camelus)
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