PT68102A - Process for the preparation of alfa fluoromethyl- -alfa amino alkanoic acids - Google Patents

Process for the preparation of alfa fluoromethyl- -alfa amino alkanoic acids

Info

Publication number
PT68102A
PT68102A PT68102A PT6810278A PT68102A PT 68102 A PT68102 A PT 68102A PT 68102 A PT68102 A PT 68102A PT 6810278 A PT6810278 A PT 6810278A PT 68102 A PT68102 A PT 68102A
Authority
PT
Portugal
Prior art keywords
alfa
fluoromethyl
preparation
alkanoic acids
amino alkanoic
Prior art date
Application number
PT68102A
Other languages
Portuguese (pt)
Other versions
PT68102B (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT68102A publication Critical patent/PT68102A/en
Publication of PT68102B publication Critical patent/PT68102B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
PT68102A 1977-06-01 1978-05-30 Process for the preparation of alpha-fluoromethyl-alpha-amino alkanoic acids PT68102B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (2)

Publication Number Publication Date
PT68102A true PT68102A (en) 1978-06-01
PT68102B PT68102B (en) 1982-06-08

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68102A PT68102B (en) 1977-06-01 1978-05-30 Process for the preparation of alpha-fluoromethyl-alpha-amino alkanoic acids

Country Status (26)

Country Link
JP (1) JPS5416423A (en)
AR (1) AR223463A1 (en)
AT (1) AT360509B (en)
AU (1) AU518479B2 (en)
CA (1) CA1120040A (en)
CH (1) CH639639A5 (en)
DD (1) DD138651A5 (en)
DE (1) DE2824116A1 (en)
DK (1) DK149841C (en)
ES (1) ES470296A1 (en)
FI (1) FI66840C (en)
FR (1) FR2392958A1 (en)
GB (1) GB1602525A (en)
GR (1) GR64495B (en)
HK (1) HK18184A (en)
HU (1) HU181911B (en)
IE (1) IE46983B1 (en)
IT (1) IT1104709B (en)
LU (1) LU79750A1 (en)
NL (1) NL190485C (en)
NO (1) NO147382C (en)
NZ (1) NZ187377A (en)
PL (1) PL115731B1 (en)
PT (1) PT68102B (en)
SE (1) SE7806440L (en)
YU (1) YU129178A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
EP0007600B1 (en) * 1978-07-24 1983-05-11 Merck & Co. Inc. Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
IL60591A (en) * 1979-07-26 1985-02-28 Merrell Toraude & Co Alkenyl fluoromethyl ketimine magnesium halides and process for their preparation
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
PH16634A (en) * 1980-06-16 1983-12-05 Merrell Dow Pharma Method of inhibiting the growth of protozoa
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
PT68102B (en) 1982-06-08
FI66840B (en) 1984-08-31
FR2392958A1 (en) 1978-12-29
NO781892L (en) 1978-12-04
CA1120040A (en) 1982-03-16
FI781674A (en) 1978-12-02
FR2392958B1 (en) 1980-10-24
IE781078L (en) 1978-12-01
AT360509B (en) 1981-01-12
GB1602525A (en) 1981-11-11
YU129178A (en) 1983-01-21
CH639639A5 (en) 1983-11-30
IT1104709B (en) 1985-10-28
HK18184A (en) 1984-03-09
DD138651A5 (en) 1979-11-14
NZ187377A (en) 1981-05-15
AU3658678A (en) 1979-12-06
DE2824116A1 (en) 1978-12-14
DK149841C (en) 1987-04-21
PL207242A1 (en) 1979-04-23
NO147382B (en) 1982-12-20
JPS641474B2 (en) 1989-01-11
PL115731B1 (en) 1981-04-30
IE46983B1 (en) 1983-11-16
DK237978A (en) 1979-01-19
DK149841B (en) 1986-10-13
DE2824116C2 (en) 1989-04-27
ES470296A1 (en) 1979-09-16
NL7805981A (en) 1978-12-05
NL190485B (en) 1993-10-18
NL190485C (en) 1994-03-16
AU518479B2 (en) 1981-10-01
GR64495B (en) 1980-03-31
NO147382C (en) 1983-03-30
SE7806440L (en) 1978-12-02
AR223463A1 (en) 1981-08-31
JPS5416423A (en) 1979-02-07
HU181911B (en) 1983-11-28
FI66840C (en) 1984-12-10
ATA393278A (en) 1980-06-15
LU79750A1 (en) 1979-02-02
IT7849637A0 (en) 1978-05-31

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