PT643963E - BIODEGRADAVEL DEVICE FOR ADMINISTRATION OF ACTIVE SUBSTANCES - Google Patents

BIODEGRADAVEL DEVICE FOR ADMINISTRATION OF ACTIVE SUBSTANCES

Info

Publication number
PT643963E
PT643963E PT94302638T PT94302638T PT643963E PT 643963 E PT643963 E PT 643963E PT 94302638 T PT94302638 T PT 94302638T PT 94302638 T PT94302638 T PT 94302638T PT 643963 E PT643963 E PT 643963E
Authority
PT
Portugal
Prior art keywords
hours
biodegradavel
administration
active substances
active ingredient
Prior art date
Application number
PT94302638T
Other languages
Portuguese (pt)
Inventor
Peter Britton
Patricia Flanagan
William P Hart
Deborah Linkin
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of PT643963E publication Critical patent/PT643963E/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00—Gas and liquid contact apparatus
    • Y10S261/26—Foam

Abstract

The invention relates to a muco-adherent, soluble device for administering active ingredients, a method of using said device, and an improved method of manufacturing said device using a continuous, enclosed mixing device capable of operating under pressure. The devices of the invention, which comprise a lyophilized foam and an active ingredient, have a dissolution time of at least about 8 hours, and preferably at least about 24 hours, and can provide for the sustained and/or controlled release of an active ingredient for up to about 24 hours.
PT94302638T 1993-08-16 1994-04-13 BIODEGRADAVEL DEVICE FOR ADMINISTRATION OF ACTIVE SUBSTANCES PT643963E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/104,785 US5458884A (en) 1992-09-10 1993-08-16 Bioerodible device for administering active ingredients

Publications (1)

Publication Number Publication Date
PT643963E true PT643963E (en) 2002-05-31

Family

ID=22302367

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94302638T PT643963E (en) 1993-08-16 1994-04-13 BIODEGRADAVEL DEVICE FOR ADMINISTRATION OF ACTIVE SUBSTANCES

Country Status (8)

Country Link
US (1) US5458884A (en)
EP (1) EP0643963B1 (en)
KR (1) KR100277483B1 (en)
AT (1) ATE208612T1 (en)
DE (1) DE69429048T2 (en)
DK (1) DK0643963T3 (en)
ES (1) ES2171165T3 (en)
PT (1) PT643963E (en)

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US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6248358B1 (en) 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
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US20020076440A1 (en) * 1999-06-25 2002-06-20 Thomas Leon Veterinary delivery systems and methods of delivering effective agents to animals
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US6943200B1 (en) 1999-10-05 2005-09-13 Procter & Gamble Company Water unstable foam compositions
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GB2355014A (en) * 1999-10-05 2001-04-11 Procter & Gamble Foams and compositions containing these foams
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US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
GB2366797A (en) * 2000-09-13 2002-03-20 Procter & Gamble Process for making foam component by pressurising/depressurising
US6756051B1 (en) * 2000-11-15 2004-06-29 Li-Lan H. Chen Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
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US7897832B2 (en) * 2001-06-14 2011-03-01 Hemcon Medical Technologies, Inc. Compositions, assemblies, and methods applied during or after a dental procedure to ameliorate fluid loss and/or promote healing, using a hydrophilic polymer sponge structure such as chitosan
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US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
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US20040151756A1 (en) * 2003-02-04 2004-08-05 Richards Anthony P. Edible low density high surface area drug vehicle, method of manufacturing low density high surface area drug vehicle
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US9204957B2 (en) 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
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WO2009134447A1 (en) 2008-05-02 2009-11-05 Providence Health System-Oregon D/B/A Providence St. Vincent Medical Center Wound dressing devices and methods
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US5354558A (en) * 1992-09-10 1994-10-11 Mcneil-Pcc, Inc. Bioerodible contraceptive suppository

Also Published As

Publication number Publication date
DE69429048D1 (en) 2001-12-20
EP0643963A3 (en) 1996-09-11
ES2171165T3 (en) 2002-09-01
EP0643963B1 (en) 2001-11-14
ATE208612T1 (en) 2001-11-15
KR940006574A (en) 1994-04-25
DE69429048T2 (en) 2002-07-11
DK0643963T3 (en) 2002-03-11
KR100277483B1 (en) 2001-09-17
US5458884A (en) 1995-10-17
EP0643963A2 (en) 1995-03-22

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