PT3777855T - Métodos de tratamento para doenças fibróticas - Google Patents

Métodos de tratamento para doenças fibróticas

Info

Publication number
PT3777855T
PT3777855T PT201944584T PT20194458T PT3777855T PT 3777855 T PT3777855 T PT 3777855T PT 201944584 T PT201944584 T PT 201944584T PT 20194458 T PT20194458 T PT 20194458T PT 3777855 T PT3777855 T PT 3777855T
Authority
PT
Portugal
Prior art keywords
cholestatic
treatment
methods
fibrotic diseases
fibrotic
Prior art date
Application number
PT201944584T
Other languages
English (en)
Original Assignee
Genfit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit filed Critical Genfit
Publication of PT3777855T publication Critical patent/PT3777855T/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
PT201944584T 2016-04-11 2017-03-13 Métodos de tratamento para doenças fibróticas PT3777855T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16305425 2016-04-11

Publications (1)

Publication Number Publication Date
PT3777855T true PT3777855T (pt) 2023-01-10

Family

ID=55755536

Family Applications (2)

Application Number Title Priority Date Filing Date
PT201944584T PT3777855T (pt) 2016-04-11 2017-03-13 Métodos de tratamento para doenças fibróticas
PT177102852T PT3442580T (pt) 2016-04-11 2017-03-13 Métodos de tratamento para doenças colestáticas e fibróticas

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT177102852T PT3442580T (pt) 2016-04-11 2017-03-13 Métodos de tratamento para doenças colestáticas e fibróticas

Country Status (24)

Country Link
US (7) US20170290812A1 (pt)
EP (3) EP3442580B1 (pt)
JP (1) JP6894923B2 (pt)
KR (1) KR102431257B1 (pt)
CN (1) CN109069648B (pt)
AU (1) AU2017249602B2 (pt)
CA (1) CA3019399A1 (pt)
DK (2) DK3442580T3 (pt)
EA (2) EA202191466A1 (pt)
ES (3) ES2935185T3 (pt)
HR (1) HRP20201954T1 (pt)
HU (2) HUE060671T2 (pt)
IL (1) IL262052B (pt)
LT (1) LT3442580T (pt)
MD (1) MD3442580T2 (pt)
MX (1) MX2018012287A (pt)
MY (1) MY195437A (pt)
PH (1) PH12018502142A1 (pt)
PL (1) PL3442580T3 (pt)
PT (2) PT3777855T (pt)
SG (2) SG10202004425XA (pt)
SI (1) SI3442580T1 (pt)
WO (1) WO2017178172A1 (pt)
ZA (1) ZA201807389B (pt)

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JP7298928B2 (ja) * 2017-03-21 2023-06-27 ノヴァリード ファーマ インク ホスホジエステラーゼの阻害及びその関連障害のための治療剤
EP3709985A1 (en) 2017-11-17 2020-09-23 Köster, Hubert [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate for use in lymphangioleiomyomatosis and other diseases
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CN110205302B (zh) * 2019-06-24 2021-03-23 扬州大学 一株分泌抗麦考酚酸单克隆抗体的细胞株、其单克隆抗体及其应用
CN110478357A (zh) * 2019-07-23 2019-11-22 哈尔滨医科大学 硝唑尼特及其体内代谢物在抗肥胖、降血脂、抗脂肪肝及抗动脉粥样硬化中的应用
CN110368498A (zh) * 2019-08-26 2019-10-25 瑞希(重庆)生物科技有限公司 一种促进伤口愈合的制剂及其制备方法
CN114630660A (zh) 2019-10-28 2022-06-14 基恩菲特公司 具有抗氧化特性的联合疗法
CN113398125B (zh) * 2020-03-16 2024-05-03 绍兴君科臻元医药科技有限公司 替唑尼特药物组合物及其医药用途
MX2023005797A (es) * 2020-11-17 2023-05-29 Genfit Metodos de tratamiento de la insuficiencia hepatica.
CN115197164A (zh) * 2021-04-12 2022-10-18 杜心赟 新型噻唑类化合物及其制备方法和用途
CN116077502A (zh) * 2021-11-05 2023-05-09 广州市妇女儿童医疗中心 叶酸在预防、诊断和治疗遗传性、感染性或过敏性疾病中的应用
WO2024074515A1 (en) * 2022-10-04 2024-04-11 Genfit Nitazoxanide for the treatment of hepatic impairment
CN117838690A (zh) * 2023-10-09 2024-04-09 中国药科大学 一种治疗以ampk激活为治疗靶点的疾病的复方药物及其应用

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Also Published As

Publication number Publication date
US11103484B2 (en) 2021-08-31
PL3442580T3 (pl) 2021-04-06
US10117856B2 (en) 2018-11-06
SG10202004425XA (en) 2020-06-29
US20180092884A1 (en) 2018-04-05
DK3777855T3 (da) 2023-01-09
US20180085354A1 (en) 2018-03-29
US20180092886A1 (en) 2018-04-05
AU2017249602A1 (en) 2018-10-18
ES2928408T3 (es) 2022-11-17
IL262052A (en) 2018-11-29
JP2019513761A (ja) 2019-05-30
US20200316031A1 (en) 2020-10-08
SG11201808402RA (en) 2018-10-30
HUE052886T2 (hu) 2021-05-28
EA201892298A1 (ru) 2019-04-30
US20190000813A1 (en) 2019-01-03
CA3019399A1 (en) 2017-10-19
PH12018502142A1 (en) 2019-07-29
US10117855B2 (en) 2018-11-06
MY195437A (en) 2023-01-20
WO2017178172A1 (en) 2017-10-19
DK3442580T3 (da) 2020-12-21
JP6894923B2 (ja) 2021-06-30
BR112018069684A2 (pt) 2019-01-29
US10130612B2 (en) 2018-11-20
US20170290812A1 (en) 2017-10-12
MX2018012287A (es) 2019-02-07
MD3442580T2 (ro) 2021-04-30
SI3442580T1 (sl) 2021-01-29
LT3442580T (lt) 2020-12-28
CN109069648B (zh) 2022-01-14
EA202191466A1 (ru) 2021-12-31
PT3442580T (pt) 2020-12-23
EP3777854A1 (en) 2021-02-17
EP3777855B1 (en) 2022-10-19
EP3442580B1 (en) 2020-09-23
ES2839453T3 (es) 2021-07-05
ZA201807389B (en) 2020-01-29
IL262052B (en) 2021-12-01
EP3442580A1 (en) 2019-02-20
US20180092885A1 (en) 2018-04-05
HRP20201954T1 (hr) 2021-02-05
EP3777854B1 (en) 2022-07-20
KR20180129934A (ko) 2018-12-05
CN109069648A (zh) 2018-12-21
US10130613B2 (en) 2018-11-20
HUE060671T2 (hu) 2023-04-28
AU2017249602B2 (en) 2022-06-16
KR102431257B1 (ko) 2022-08-10
EP3777855A1 (en) 2021-02-17
ES2935185T3 (es) 2023-03-02

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