PT2964775T - Promotores de leveduras para a expressão proteica - Google Patents

Promotores de leveduras para a expressão proteica

Info

Publication number
PT2964775T
PT2964775T PT14760869T PT14760869T PT2964775T PT 2964775 T PT2964775 T PT 2964775T PT 14760869 T PT14760869 T PT 14760869T PT 14760869 T PT14760869 T PT 14760869T PT 2964775 T PT2964775 T PT 2964775T
Authority
PT
Portugal
Prior art keywords
protein expression
yeast promoters
promoters
yeast
protein
Prior art date
Application number
PT14760869T
Other languages
English (en)
Inventor
I Tolstorukov Ilya
M Cregg James
g chappell Thomas
R Madden Knut
Original Assignee
Biogrammatics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogrammatics Inc filed Critical Biogrammatics Inc
Publication of PT2964775T publication Critical patent/PT2964775T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/60Vectors containing traps for, e.g. exons, promoters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01022Alpha-galactosidase (3.2.1.22)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT14760869T 2013-03-08 2014-03-07 Promotores de leveduras para a expressão proteica PT2964775T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361775029P 2013-03-08 2013-03-08

Publications (1)

Publication Number Publication Date
PT2964775T true PT2964775T (pt) 2019-05-06

Family

ID=51492025

Family Applications (1)

Application Number Title Priority Date Filing Date
PT14760869T PT2964775T (pt) 2013-03-08 2014-03-07 Promotores de leveduras para a expressão proteica

Country Status (10)

Country Link
US (3) US10676750B2 (pt)
EP (3) EP2964775B1 (pt)
CN (1) CN105358706A (pt)
BR (1) BR112015021785A2 (pt)
CA (1) CA2904333C (pt)
DK (2) DK3527667T3 (pt)
ES (3) ES2856265T3 (pt)
HU (1) HUE042897T2 (pt)
PT (1) PT2964775T (pt)
WO (1) WO2014138679A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2964765B1 (en) 2013-03-08 2019-05-08 Keck Graduate Institute of Applied Life Sciences Yeast promoters from pichia pastoris
US10676750B2 (en) 2013-03-08 2020-06-09 Biogrammatics, Inc. Yeast promoters for protein expression
WO2016077457A1 (en) 2014-11-11 2016-05-19 Clara Foods Co. Methods and compositions for egg white protein production
WO2017058884A2 (en) 2015-09-28 2017-04-06 The Trustees Of Columbia University In The City Of New York Modified bacterial protein expression system
CN109536395A (zh) * 2018-02-07 2019-03-29 四川润格生物科技有限公司 一种高表达β-甘露聚糖酶的毕赤酵母工程菌株及应用
KR102131882B1 (ko) * 2018-02-14 2020-08-06 씨제이제일제당 주식회사 효모를 이용하여 이취가 개선된 발효 조성물의 제조방법
BR112022000545A2 (pt) 2019-07-11 2022-04-05 Clara Foods Co Composições de proteína e produtos de consumo destas
US10927360B1 (en) 2019-08-07 2021-02-23 Clara Foods Co. Compositions comprising digestive enzymes
WO2022115636A1 (en) * 2020-11-25 2022-06-02 Esperovax Inc. Cell viability switch for genetically modified organisms
WO2023184539A1 (zh) * 2022-04-02 2023-10-05 武汉远大弘元股份有限公司 一种甲醇诱导启动子及其在制备丙谷二肽中的应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US14715A (en) * 1856-04-22 Improvement in cultivators
US14716A (en) * 1856-04-22 Machine for digging peat
US7078035B2 (en) 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
ES2248067T3 (es) 1999-03-31 2006-03-16 Cornell Research Foundation, Inc. Fosfatasas con actividad de fitasa mejorada.
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
GB0126164D0 (en) 2001-10-31 2002-01-02 Danisco Sequences
CA2465202C (en) 2001-10-31 2014-01-21 Phytex, Llc Phytase-containing animal food and method
MY139056A (en) 2001-12-28 2009-08-28 Ab Enzymes Gmbh Microbially-expressed thermotolerant phytase for animal feed
US7226771B2 (en) 2002-04-19 2007-06-05 Diversa Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
US7943360B2 (en) 2002-04-19 2011-05-17 Verenium Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
WO2005123911A2 (en) 2004-06-21 2005-12-29 Novozymes A/S Proteases
AT501955B1 (de) * 2005-02-23 2007-08-15 Univ Graz Tech Mutierte aox1-promotoren
EP1951877B1 (en) * 2005-11-16 2010-11-03 Korea Research Institute of Bioscience and Biotechnology Translational elongation factor promoter from pichia pastoris and method for producing recombinant protein using the same
CN101460612B (zh) 2006-04-04 2015-05-06 诺维信公司 肌醇六磷酸酶变体
EP2001999B1 (en) 2006-04-04 2012-05-16 Novozymes A/S Phytase variants
US8222386B2 (en) 2006-10-10 2012-07-17 Keck Graduate Institute P. pastoris ADH promoter and use thereof to direct expression of proteins
JP5290997B2 (ja) 2007-01-26 2013-09-18 ノボザイムス アクティーゼルスカブ ピキアにおけるメタノール誘導性プロモーターからのメタノール非依存的誘導の方法
BRPI0810357A2 (pt) 2007-04-20 2014-10-07 Polymun Scient Immunbio Forsch Método para aumentar a secreção de uma poi a partir de uma célula eucariótica, uso de uma sequência de nucleotídeo, sequência de nucleotídeo, sequência promotora de levedura, vetor de expressão eucariótico, e, usos de um vetor de expressão e de uma sequência promotora de levedura.
CN102105589A (zh) * 2008-07-11 2011-06-22 诺维信公司 巴斯德毕赤酵母(Pichia pastoris) DAS启动子变体
CN102333872B (zh) * 2009-02-25 2014-07-09 默沙东公司 在糖工程化的酵母巴斯德毕赤酵母中对半乳糖同化途径的代谢工程化
WO2012129036A2 (en) * 2011-03-22 2012-09-27 Merck Sharp & Dohme Corp. Promoters for high level recombinant expression in fungal host cells
CN102994501B (zh) 2012-10-15 2018-04-27 华南理工大学 具有组成型启动子活性的dna及其应用和巴斯德毕赤酵母表达载体
US10676750B2 (en) 2013-03-08 2020-06-09 Biogrammatics, Inc. Yeast promoters for protein expression
EP2964765B1 (en) 2013-03-08 2019-05-08 Keck Graduate Institute of Applied Life Sciences Yeast promoters from pichia pastoris
US9150870B2 (en) 2013-03-15 2015-10-06 Lonza Ltd. Constitutive promoter
DK2862933T3 (da) * 2013-07-05 2019-11-18 Bisy E U Bidirektionel promotor
EP4276191A3 (en) * 2017-08-23 2023-12-27 Novartis AG Multi-copy gene protein expression system

Also Published As

Publication number Publication date
HUE042897T2 (hu) 2019-07-29
WO2014138679A1 (en) 2014-09-12
EP3839055A2 (en) 2021-06-23
EP2964775B1 (en) 2019-01-09
CA2904333A1 (en) 2014-09-12
EP3839055B1 (en) 2023-08-23
DK2964775T3 (en) 2019-04-15
BR112015021785A2 (pt) 2017-08-29
CN105358706A (zh) 2016-02-24
US10676750B2 (en) 2020-06-09
ES2961268T3 (es) 2024-03-11
DK3527667T3 (da) 2021-02-22
US20210032643A1 (en) 2021-02-04
EP3839055A3 (en) 2021-10-20
ES2856265T3 (es) 2021-09-27
EP2964775A1 (en) 2016-01-13
EP2964775A4 (en) 2017-03-01
CA2904333C (en) 2024-06-25
US20160024511A1 (en) 2016-01-28
ES2716619T3 (es) 2019-06-13
EP3527667A2 (en) 2019-08-21
EP3527667A3 (en) 2019-10-02
EP3527667B1 (en) 2020-11-25
EP3839055C0 (en) 2023-08-23
US11555194B2 (en) 2023-01-17
US20230340507A1 (en) 2023-10-26

Similar Documents

Publication Publication Date Title
HK1257261A1 (zh) 抗fcrh5抗體
GB201322583D0 (en) Antibodies
EP3839055C0 (en) YEAST PROMOTERS FOR PROTEIN EXPRESSION
EP2948001A4 (en) IMPROVEMENTS IN MICROALGUE FLOUR
HK1220142A1 (zh) 抗體
HRP20190434T1 (hr) Fuzijski protein
GB201308658D0 (en) Antibodies
GB201315486D0 (en) Antibodies
EP3027762A4 (en) Phytase
RS64292B1 (sr) Fotobioreaktor
IL245488A0 (en) Anti- ccl17 antibodies
EP2976622A4 (en) Protein standard
GB201308057D0 (en) Protein
SG10201507721SA (en) CHO-GMT Recombinant Protein Expression
GB201401955D0 (en) Protein
GB201304973D0 (en) Recombinant protein
GB201302030D0 (en) Protein
GB201302031D0 (en) Protein
GB201321109D0 (en) Synthetic promoters
GB201318283D0 (en) Antibodies