PT2914574T - Processo novo - Google Patents

Processo novo

Info

Publication number
PT2914574T
PT2914574T PT138016886T PT13801688T PT2914574T PT 2914574 T PT2914574 T PT 2914574T PT 138016886 T PT138016886 T PT 138016886T PT 13801688 T PT13801688 T PT 13801688T PT 2914574 T PT2914574 T PT 2914574T
Authority
PT
Portugal
Prior art keywords
new process
new
Prior art date
Application number
PT138016886T
Other languages
English (en)
Inventor
Radaelli Stefano
Zurlo Giuseppe
Eklund Lars
Eek Margus
Maasalu Ants
Schmidt Malle
Original Assignee
Cambrex Karlskoga Ab
Cambrex Profarmaco Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambrex Karlskoga Ab, Cambrex Profarmaco Milano filed Critical Cambrex Karlskoga Ab
Publication of PT2914574T publication Critical patent/PT2914574T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/12—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT138016886T 2012-11-01 2013-11-01 Processo novo PT2914574T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1219627.5A GB201219627D0 (en) 2012-11-01 2012-11-01 New process

Publications (1)

Publication Number Publication Date
PT2914574T true PT2914574T (pt) 2019-12-11

Family

ID=47358979

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138016886T PT2914574T (pt) 2012-11-01 2013-11-01 Processo novo

Country Status (10)

Country Link
US (1) US9771317B2 (pt)
EP (1) EP2914574B1 (pt)
CA (1) CA2889650C (pt)
DK (1) DK2914574T3 (pt)
ES (1) ES2756000T3 (pt)
GB (1) GB201219627D0 (pt)
HR (1) HRP20191880T1 (pt)
PL (1) PL2914574T3 (pt)
PT (1) PT2914574T (pt)
WO (1) WO2014068333A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016021711A1 (ja) * 2014-08-07 2016-02-11 株式会社エーピーアイ コーポレーション アミノ酸誘導体の製造方法
EP3375771A4 (en) * 2015-11-13 2019-07-17 API Corporation PROCESS FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATE PRODUCT THEREOF
CN105949074B (zh) * 2016-06-03 2018-03-02 南京红杉生物科技有限公司 一种o‑甲基‑d‑丝氨酸的合成方法
CN114524746B (zh) * 2022-01-21 2022-11-11 河北广祥制药有限公司 拉考沙胺晶型的制备方法
CN115825300A (zh) * 2022-11-30 2023-03-21 山东百诺医药股份有限公司 一种检测拉考沙胺对映异构体的反相液相色谱方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1028557B (de) 1957-03-06 1958-04-24 Basf Ag Verfahren zur Herstellung von ª‰-Alkoxy-ª‡-chlorpropionsaeureestern
US5378729A (en) 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5773475A (en) 1997-03-17 1998-06-30 Research Corporation Technologies, Inc. Anticonvulsant enantiomeric amino acid derivatives
US6048899A (en) 1997-03-17 2000-04-11 Research Corporation Tech., Inc. Anticonvulsant enantiomeric amino acid derivatives
EP1642889A1 (en) 2004-10-02 2006-04-05 Schwarz Pharma Ag Improved synthesis scheme for lacosamide
US8093426B2 (en) 2007-12-04 2012-01-10 Ranbaxy Laboratories Limited Intermediate compounds and their use in preparation of lacosamide
MX2011004324A (es) 2008-11-07 2011-09-21 Ucb Pharma Gmbh Proceso novedoso para la preparacion de derivados de aminoacidos.
CN101591300B (zh) 2009-02-19 2011-05-04 成都伊诺达博医药科技有限公司 合成拉考沙胺的新方法
WO2011061610A2 (en) 2009-11-19 2011-05-26 Ranbaxy Laboratories Limited Processes for preparation of polymorphic forms of lacosamide
IT1398044B1 (it) 2010-01-29 2013-02-07 Archimica Srl Processo per la preparazione della lacosamide
US20130095535A1 (en) 2010-06-15 2013-04-18 Medichem, S.A. Enzymatic resolution of racemic (2r,s)-2-(acetylamino)-3-methoxy-n-(phenylmethyl)propanamide
WO2012041986A1 (en) 2010-10-01 2012-04-05 Ucb Pharma Gmbh Process for the preparation of amino acid derivatives
GB201020026D0 (en) 2010-11-25 2011-01-12 Cambrex Karlskoga Ab New process

Also Published As

Publication number Publication date
HRP20191880T1 (hr) 2020-03-20
US20150299105A1 (en) 2015-10-22
EP2914574A2 (en) 2015-09-09
CA2889650A1 (en) 2014-05-08
US9771317B2 (en) 2017-09-26
GB201219627D0 (en) 2012-12-12
ES2756000T3 (es) 2020-04-24
WO2014068333A3 (en) 2014-06-26
WO2014068333A2 (en) 2014-05-08
DK2914574T3 (da) 2019-11-25
CA2889650C (en) 2021-08-31
EP2914574B1 (en) 2019-10-02
PL2914574T3 (pl) 2020-05-18

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