PT2861573T - Derivados de oxatiazina como agentes antibacterianos e anticancerígeno - Google Patents
Derivados de oxatiazina como agentes antibacterianos e anticancerígenoInfo
- Publication number
- PT2861573T PT2861573T PT137341624T PT13734162T PT2861573T PT 2861573 T PT2861573 T PT 2861573T PT 137341624 T PT137341624 T PT 137341624T PT 13734162 T PT13734162 T PT 13734162T PT 2861573 T PT2861573 T PT 2861573T
- Authority
- PT
- Portugal
- Prior art keywords
- antibacterial
- anticancer agents
- oxathiazine
- derivatives
- oxathiazine derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/39—Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
- C07D291/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/10—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms two oxygen atoms and one sulfur atom, e.g. cyclic sulfates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261661092P | 2012-06-18 | 2012-06-18 | |
US201261694452P | 2012-08-29 | 2012-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2861573T true PT2861573T (pt) | 2017-11-14 |
Family
ID=48746589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT137341624T PT2861573T (pt) | 2012-06-18 | 2013-06-17 | Derivados de oxatiazina como agentes antibacterianos e anticancerígeno |
Country Status (8)
Country | Link |
---|---|
US (3) | US9241943B2 (pt) |
EP (1) | EP2861573B1 (pt) |
DK (1) | DK2861573T3 (pt) |
ES (1) | ES2644870T3 (pt) |
HU (1) | HUE034822T2 (pt) |
PL (1) | PL2861573T3 (pt) |
PT (1) | PT2861573T (pt) |
WO (1) | WO2013190355A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2861573T3 (da) * | 2012-06-18 | 2017-11-13 | Geistlich Pharma Ag | Oxathiazin-derivater som antibakterielle og anticancer-stoffer |
US11591302B2 (en) | 2014-12-19 | 2023-02-28 | Geistlich Pharm A Ag | Processes for preparing oxathiazin-like compounds |
DK3233813T3 (da) * | 2014-12-19 | 2022-03-07 | Geistlich Pharma Ag | Fremgangsmåder til fremstilling af oxathiazin-lignende forbindelser |
US11541061B2 (en) | 2016-01-11 | 2023-01-03 | Cormedix Inc. | Neuroblastoma treatment with taurolidine hydrolysis products |
ES2945712T3 (es) * | 2016-03-18 | 2023-07-06 | Geistlich Pharma Ag | Método de tratamiento de cáncer de mama triple negativo |
CN109476615A (zh) * | 2016-04-07 | 2019-03-15 | 盖斯特里希医药公司 | 制备噁噻嗪类化合物的方法 |
KR102614466B1 (ko) * | 2016-11-14 | 2023-12-14 | 비온디스 비.브이. | 단일-보호된 알파, 오메가-디아미노 알칸의 제조 방법 |
AU2019330831A1 (en) * | 2018-08-28 | 2021-04-29 | Cormedix Inc. | Methods and compositions for treating neuroblastoma in a juvenile mammalian body |
CN114096255A (zh) * | 2019-05-22 | 2022-02-25 | 盖斯特里希医药公司 | 用于治疗、预防、抑制或减少细胞因子释放的噁噻嗪二氧化物 |
WO2022229907A1 (en) * | 2021-04-29 | 2022-11-03 | Geistlich Pharma Ag | Antimicrobial and anticancer agents |
WO2024028846A1 (en) * | 2022-08-05 | 2024-02-08 | Geistlich Pharma Ag | Combination therapy for treating cancers |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1160443B (de) * | 1961-11-30 | 1964-01-02 | Hoechst Ag | Verfahren zur Herstellung von Tetrahydro-oxathiazin-dioxyden |
DE1234988B (de) * | 1964-11-28 | 1967-02-23 | Bayer Ag | Verfahren zur Herstellung von Copolymerisaten des Trioxans |
GB8617482D0 (en) | 1986-07-17 | 1986-08-28 | Geistlich Soehne Ag | Pharmaceutical composition |
US6117868A (en) * | 1998-09-16 | 2000-09-12 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Treatment of gastrointestinal ulcers or gastritis caused by microbial infection |
EP1248625A2 (en) | 1999-12-06 | 2002-10-16 | Rhode Island Hospital | Use of methylol-containing compounds for the manufacture of a medicament for the treatment of tumors |
DK2861573T3 (da) * | 2012-06-18 | 2017-11-13 | Geistlich Pharma Ag | Oxathiazin-derivater som antibakterielle og anticancer-stoffer |
-
2013
- 2013-06-17 DK DK13734162.4T patent/DK2861573T3/da active
- 2013-06-17 PT PT137341624T patent/PT2861573T/pt unknown
- 2013-06-17 PL PL13734162T patent/PL2861573T3/pl unknown
- 2013-06-17 US US14/409,352 patent/US9241943B2/en active Active
- 2013-06-17 WO PCT/IB2013/001261 patent/WO2013190355A1/en active Application Filing
- 2013-06-17 ES ES13734162.4T patent/ES2644870T3/es active Active
- 2013-06-17 EP EP13734162.4A patent/EP2861573B1/en active Active
- 2013-06-17 HU HUE13734162A patent/HUE034822T2/en unknown
-
2015
- 2015-12-03 US US14/958,225 patent/US9624187B2/en active Active
-
2017
- 2017-03-29 US US15/472,550 patent/US9844555B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL2861573T3 (pl) | 2018-02-28 |
EP2861573A1 (en) | 2015-04-22 |
US20160159759A1 (en) | 2016-06-09 |
US9844555B2 (en) | 2017-12-19 |
EP2861573B1 (en) | 2017-08-30 |
WO2013190355A1 (en) | 2013-12-27 |
US9241943B2 (en) | 2016-01-26 |
HUE034822T2 (en) | 2018-03-28 |
US20150182534A1 (en) | 2015-07-02 |
US20170196876A1 (en) | 2017-07-13 |
ES2644870T3 (es) | 2017-11-30 |
DK2861573T3 (da) | 2017-11-13 |
US9624187B2 (en) | 2017-04-18 |
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