PT2809681T - Anticorpos anti-asic1 e suas utilizações - Google Patents

Anticorpos anti-asic1 e suas utilizações

Info

Publication number
PT2809681T
PT2809681T PT13702876T PT13702876T PT2809681T PT 2809681 T PT2809681 T PT 2809681T PT 13702876 T PT13702876 T PT 13702876T PT 13702876 T PT13702876 T PT 13702876T PT 2809681 T PT2809681 T PT 2809681T
Authority
PT
Portugal
Prior art keywords
asic1 antibodies
asic1
antibodies
Prior art date
Application number
PT13702876T
Other languages
English (en)
Inventor
Macdonald Lynn
L Lacroix-Fralish Michael
Gao Min
R Morra Marc
M Alessandri-Haber Nicole
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47666522&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2809681(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of PT2809681T publication Critical patent/PT2809681T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
PT13702876T 2012-01-31 2013-01-30 Anticorpos anti-asic1 e suas utilizações PT2809681T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261592837P 2012-01-31 2012-01-31
US201261644038P 2012-05-08 2012-05-08
US201261692925P 2012-08-24 2012-08-24

Publications (1)

Publication Number Publication Date
PT2809681T true PT2809681T (pt) 2019-02-18

Family

ID=47666522

Family Applications (2)

Application Number Title Priority Date Filing Date
PT13702876T PT2809681T (pt) 2012-01-31 2013-01-30 Anticorpos anti-asic1 e suas utilizações
PT182018234T PT3453723T (pt) 2012-01-31 2013-01-30 Anticorpos anti-asic1 e suas utilizações

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT182018234T PT3453723T (pt) 2012-01-31 2013-01-30 Anticorpos anti-asic1 e suas utilizações

Country Status (33)

Country Link
US (3) US9150648B2 (pt)
EP (2) EP3453723B1 (pt)
JP (1) JP6302844B2 (pt)
KR (1) KR102111941B1 (pt)
CN (1) CN104093738B (pt)
AR (1) AR089852A1 (pt)
AU (1) AU2013215254B2 (pt)
CA (1) CA2862332C (pt)
CL (1) CL2014002019A1 (pt)
CO (1) CO7020877A2 (pt)
CY (2) CY1121368T1 (pt)
DK (2) DK2809681T3 (pt)
EA (1) EA028647B1 (pt)
ES (2) ES2886123T3 (pt)
HK (1) HK1199269A1 (pt)
HR (2) HRP20211541T1 (pt)
HU (2) HUE056335T2 (pt)
IL (2) IL233410A0 (pt)
IN (1) IN2014CN04645A (pt)
JO (1) JO3547B1 (pt)
LT (2) LT3453723T (pt)
MX (1) MX358518B (pt)
MY (1) MY168748A (pt)
NZ (1) NZ626242A (pt)
PH (1) PH12014501613B1 (pt)
PL (2) PL2809681T3 (pt)
PT (2) PT2809681T (pt)
RS (2) RS58439B1 (pt)
SG (1) SG11201403222UA (pt)
SI (2) SI3453723T1 (pt)
TW (1) TWI591073B (pt)
UY (1) UY34603A (pt)
WO (1) WO2013116296A1 (pt)

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BR122018009619B1 (pt) 2014-05-16 2024-01-02 Ablynx N.V Domínios variáveis de imunoglobulina aperfeiçoados
RU2746738C2 (ru) 2014-05-16 2021-04-20 Аблинкс Нв Улучшенные вариабельные домены иммуноглобулина
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CN105713089B (zh) * 2016-02-26 2019-08-06 上海科技大学 一种特异性抑制酸敏感离子通道i型的全人抗体
WO2018085441A1 (en) * 2016-11-01 2018-05-11 Berg Llc Filamin b binding proteins and uses thereof
CN111936517A (zh) * 2018-01-26 2020-11-13 瑞泽恩制药公司 抗tmprss2抗体和抗原结合片段
EP3980456A4 (en) * 2019-06-04 2023-01-18 Shanghaitech University AFFINITY MATURED ANTI-ASIC1A ANTIBODIES
JP2022540611A (ja) * 2019-07-11 2022-09-16 メモリアル スローン ケタリング キャンサー センター Dll3をターゲッティングする抗体とその使用
CA3148131A1 (en) * 2019-07-23 2021-01-28 Shanghaitech University Asic1 channel antagonist antibody
WO2021050857A1 (en) * 2019-09-13 2021-03-18 Memorial Sloan-Kettering Cancer Center Anti-cd371 antibodies and uses thereof
AU2022326544A1 (en) * 2021-08-09 2024-02-29 Merck Patent Gmbh Proteins that decouple t cell-mediated tumor cytotoxicity from release of pro-inflammatory cytokines
CA3230628A1 (en) * 2021-09-02 2023-03-09 John T. POIRIER Anti-dll3 antibodies and uses thereof

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Also Published As

Publication number Publication date
KR102111941B1 (ko) 2020-05-18
PH12014501613A1 (en) 2014-10-13
EP3453723A2 (en) 2019-03-13
CY1124778T1 (el) 2022-11-25
RS58439B1 (sr) 2019-04-30
ES2886123T3 (es) 2021-12-16
PT3453723T (pt) 2021-09-07
EP2809681A1 (en) 2014-12-10
TWI591073B (zh) 2017-07-11
HUE042531T2 (hu) 2019-07-29
MY168748A (en) 2018-11-30
TW201335182A (zh) 2013-09-01
CO7020877A2 (es) 2014-08-11
EA028647B1 (ru) 2017-12-29
EP3453723A3 (en) 2019-04-10
EP3453723B1 (en) 2021-08-11
PH12014501613B1 (en) 2014-10-13
ES2707599T3 (es) 2019-04-04
IN2014CN04645A (pt) 2015-09-18
US10513557B2 (en) 2019-12-24
DK3453723T3 (da) 2021-09-13
MX2014008541A (es) 2014-10-24
SI2809681T1 (sl) 2019-04-30
JP2015508063A (ja) 2015-03-16
HRP20211541T1 (hr) 2021-12-24
CA2862332A1 (en) 2013-08-08
CA2862332C (en) 2021-05-18
HK1199269A1 (en) 2015-06-26
IL233410A0 (en) 2014-08-31
BR112014018651A2 (pt) 2017-07-04
RS62454B1 (sr) 2021-11-30
JO3547B1 (ar) 2020-07-05
WO2013116296A1 (en) 2013-08-08
AR089852A1 (es) 2014-09-24
SG11201403222UA (en) 2014-07-30
MX358518B (es) 2018-08-24
AU2013215254A1 (en) 2014-07-03
LT3453723T (lt) 2021-09-10
HUE056335T2 (hu) 2022-02-28
JP6302844B2 (ja) 2018-03-28
LT2809681T (lt) 2019-02-11
UY34603A (es) 2013-07-31
US20180222976A1 (en) 2018-08-09
CL2014002019A1 (es) 2015-01-16
AU2013215254B2 (en) 2017-08-31
US9150648B2 (en) 2015-10-06
HRP20190358T1 (hr) 2019-04-05
CN104093738B (zh) 2018-05-18
IL254416A0 (en) 2017-11-30
US20160002332A1 (en) 2016-01-07
PL2809681T3 (pl) 2019-05-31
EA201491452A1 (ru) 2014-11-28
CN104093738A (zh) 2014-10-08
CY1121368T1 (el) 2020-05-29
KR20140125363A (ko) 2014-10-28
EP2809681B1 (en) 2018-12-05
DK2809681T3 (en) 2019-03-11
IL254416B (en) 2018-03-29
NZ626242A (en) 2017-02-24
US20130195878A1 (en) 2013-08-01
PL3453723T3 (pl) 2022-01-03
SI3453723T1 (sl) 2021-11-30

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