PT2702871T - Biotecido de colagénio e sua utilização - Google Patents

Biotecido de colagénio e sua utilização

Info

Publication number
PT2702871T
PT2702871T PT13181876T PT13181876T PT2702871T PT 2702871 T PT2702871 T PT 2702871T PT 13181876 T PT13181876 T PT 13181876T PT 13181876 T PT13181876 T PT 13181876T PT 2702871 T PT2702871 T PT 2702871T
Authority
PT
Portugal
Prior art keywords
collagen biofabric
biofabric
collagen
Prior art date
Application number
PT13181876T
Other languages
English (en)
Inventor
J Hariri Robert
M Kaplunovsky Aleksandr
A Murphy Patricia
Original Assignee
Celularity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celularity Inc filed Critical Celularity Inc
Publication of PT2702871T publication Critical patent/PT2702871T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92Amnion; Decellularised dermis or mucosa
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
PT13181876T 2002-03-26 2003-03-26 Biotecido de colagénio e sua utilização PT2702871T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/106,653 US20030187515A1 (en) 2002-03-26 2002-03-26 Collagen biofabric and methods of preparing and using the collagen biofabric

Publications (1)

Publication Number Publication Date
PT2702871T true PT2702871T (pt) 2019-02-01

Family

ID=28452543

Family Applications (1)

Application Number Title Priority Date Filing Date
PT13181876T PT2702871T (pt) 2002-03-26 2003-03-26 Biotecido de colagénio e sua utilização

Country Status (16)

Country Link
US (2) US20030187515A1 (pt)
EP (4) EP2702871B1 (pt)
JP (3) JP4615223B2 (pt)
KR (1) KR100999247B1 (pt)
CN (1) CN1791331A (pt)
AU (3) AU2003226018B2 (pt)
CA (1) CA2479903C (pt)
DK (2) DK2700309T3 (pt)
ES (2) ES2526088T3 (pt)
HK (1) HK1085384A1 (pt)
IL (2) IL164220A0 (pt)
MX (1) MXPA04009188A (pt)
NZ (1) NZ535799A (pt)
PT (1) PT2702871T (pt)
WO (1) WO2003082201A2 (pt)
ZA (1) ZA200407650B (pt)

Families Citing this family (260)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
WO2002046373A1 (en) * 2000-12-06 2002-06-13 Hariri Robert J Method of collecting placental stem cells
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
ES2549161T3 (es) 2001-02-14 2015-10-23 Anthrogenesis Corporation Placenta post-parto de mamífero, su uso y células madre placentarias de la misma
EP2336299A1 (en) * 2001-02-14 2011-06-22 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US6942802B2 (en) * 2001-04-13 2005-09-13 Wyeth Holdings Corporation Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
JP3888573B2 (ja) * 2001-06-29 2007-03-07 富士電機ホールディングス株式会社 ハンダ組成物
AU2003262187A1 (en) * 2002-04-12 2003-10-27 Celgene Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
NZ536050A (en) * 2002-04-12 2007-11-30 Celgene Corp Methods of identifying modulators of angiogenesis using stem cells with the proviso the stems cells are not totipotent
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
EP1571910A4 (en) 2002-11-26 2009-10-28 Anthrogenesis Corp CYTOTHERAPEUTIC AGENTS, CYTOTHERAPEUTIC UNITS AND METHODS OF TREATMENT IN WHICH THEY INTERVENE
GB0321337D0 (en) * 2003-09-11 2003-10-15 Massone Mobile Advertising Sys Method and system for distributing advertisements
GB0322145D0 (en) * 2003-09-22 2003-10-22 Howmedica Internat S De R L Apparatus for use in the regeneration of structured human tissue
EP2335650B1 (en) 2003-12-11 2012-10-03 Isto Technologies Inc. Particulate cartilage system
US7775965B2 (en) * 2004-03-09 2010-08-17 The Board Of Regents Of The University Of Oklahoma Decellularized grafts from umbilical cord vessels and process for preparing and using same
US20050287223A1 (en) * 2004-06-23 2005-12-29 Peyman Gholam A Use of amniotic membrane as biocompatible devices
US8802651B2 (en) * 2004-06-30 2014-08-12 Abbott Medical Optics Inc. Hyaluronic acid in the enhancement of lens regeneration
US8512730B2 (en) 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
US20060190017A1 (en) * 2004-11-19 2006-08-24 Cyr John S Fibrin sealants and platelet concentrates applied to effect hemostasis at the interface of an implantable medical device with body tissue
JP2006176499A (ja) * 2004-11-25 2006-07-06 Nippon Seibutsu Seizai:Kk 眼疾患治療剤
US20070015685A1 (en) * 2005-04-04 2007-01-18 Naomi Balaban Bone cement compositions and the like comprising an RNAIII-inhibiting peptide
WO2006129673A1 (ja) * 2005-05-30 2006-12-07 Arblast Co., Ltd. 組織再建用材料及びその使用
WO2007005807A2 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
US7928280B2 (en) * 2005-07-13 2011-04-19 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
WO2007009061A2 (en) * 2005-07-13 2007-01-18 Anthrogenesis Corporation Ocular plug formed from placenta derived collagen biofabric
GB0514567D0 (en) * 2005-07-15 2005-08-24 Univ Nottingham Surgical membrane
US7837673B2 (en) 2005-08-08 2010-11-23 Innovative Therapies, Inc. Wound irrigation device
JP4977345B2 (ja) * 2005-08-26 2012-07-18 国立大学法人富山大学 乾燥羊膜及び羊膜の乾燥処理方法
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
WO2007023750A1 (ja) * 2005-08-26 2007-03-01 National University Corporation University Of Toyama 乾燥羊膜及び羊膜の乾燥処理方法
US20070074980A1 (en) * 2005-09-02 2007-04-05 Bankoski Brian R Implant rehydration packages and methods of use
AU2006295080A1 (en) * 2005-09-21 2007-04-05 Medtronic, Inc. Composite heart valve apparatus manufactured using techniques involving laser machining of tissue
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
AU2006294581B2 (en) 2005-09-27 2011-11-03 Tissuetech, Inc. Amniotic membrane preparations and purified compositions and methods of use
WO2007047465A1 (en) * 2005-10-13 2007-04-26 Anthrogenesis Corporation Production of oligodendrocytes from placenta-derived stem cells
WO2007047468A2 (en) 2005-10-13 2007-04-26 Anthrogenesis Corporation Immunomodulation using placental stem cells
SG184751A1 (en) * 2005-10-26 2012-10-30 Jan-Eric W Ahlfors Acellular bioabsorbable tissue regeneration matrices produced by incubating acellular blood products
ZA200804718B (en) 2005-12-29 2010-04-28 Anthrogenesis Corp Co-culture of placental stem cells and stem cells from a second source
NZ595786A (en) 2005-12-29 2013-05-31 Anthrogenesis Corp Placental stem cell populations
AU2006332680A1 (en) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Improved composition for collecting and preserving placental stem cells and methods of using the composition
CN101501185A (zh) * 2006-06-09 2009-08-05 人类起源公司 胎盘巢(placental niche)及其培养干细胞的用途
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
AU2013203211B2 (en) * 2006-10-06 2015-05-28 Celularity Inc. Native (telopeptide) placental collagen compositions
EP2076279B1 (en) 2006-10-06 2014-08-27 Anthrogenesis Corporation Native (telopeptide) placental collagen compositions
WO2008051568A2 (en) 2006-10-23 2008-05-02 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
EP2097116B1 (en) * 2006-12-22 2012-09-12 Laboratoire Medidom S.A. In situ system for intra-articular chondral and osseous tissue repair
KR100795708B1 (ko) * 2006-12-26 2008-01-17 주식회사 알앤엘바이오 인간 양막 상피세포 유래 성체 줄기세포의 분리 및 배양방법
EP2129775A1 (en) 2007-02-12 2009-12-09 Anthrogenesis Corporation Hepatocytes and chondrocytes from adherent placental stem cells; and cd34+, cd45- placental stem cell-enriched cell populations
EP2630959A1 (en) * 2007-02-12 2013-08-28 Anthrogenesis Corporation Treatment of inflammatory diseases using placental stem cells
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
AU2008237732B2 (en) * 2007-04-16 2014-05-22 Covidien Ag Methods and compositions for tissue regeneration
TWM322542U (en) * 2007-05-23 2007-11-21 Universal Scient Ind Co Ltd Testing machine
DE102007037051A1 (de) * 2007-07-24 2009-01-29 Aesculap Ag Flächiges Implantat
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
EP2197270B8 (en) 2007-09-07 2020-03-04 Surgical Biologics, LLC Placental tissue grafts and improved methods of preparing and using the same
US20090069843A1 (en) * 2007-09-10 2009-03-12 Agnew Charles W Fistula plugs including a hydration resistant component
WO2009042201A1 (en) * 2007-09-26 2009-04-02 Celgene Cellular Therapeutics Angiogenic cells from human placental perfusate
KR20230065354A (ko) * 2007-09-28 2023-05-11 셀룰래리티 인코포레이티드 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법
WO2009061447A2 (en) * 2007-11-07 2009-05-14 Anthrogenesis Corporation Treatment of premature birth complications
EP2225361A1 (en) * 2007-11-28 2010-09-08 Organogenesis, Inc. Bioengineered tissue constructs and methods for production and use
US20090163990A1 (en) * 2007-12-19 2009-06-25 Chunlin Yang Decellularized omentum matrix and uses thereof
KR101572634B1 (ko) 2008-04-04 2015-12-01 포사이트 비젼4, 인크. 통증 관리 및 시력을 위한 치료 장치
CN102056619A (zh) 2008-04-18 2011-05-11 科尔普兰特有限公司 产生和使用原胶原的方法
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
EP2282749A4 (en) * 2008-04-25 2011-08-17 Allosource ANTI-ADHESIVE BARRIER DRESSING COMPRISING A TREATED AMNIOTIC FABRIC AND METHOD OF USE
CN103751842A (zh) * 2008-07-30 2014-04-30 米辛瑟斯有限公司 衍生自前胃胞外基质的组织支架
US20100080840A1 (en) * 2008-07-31 2010-04-01 Michael Cho Hybrid superporous hydrogel scaffold for cornea regeneration
PE20110399A1 (es) * 2008-08-20 2011-06-22 Anthrogenesis Corp Tratamiento de la apoplejia utilizando celulas placentarias aisladas
CA2734236C (en) 2008-08-20 2020-08-25 Anthrogenesis Corporation Improved cell composition and methods of making the same
NZ591293A (en) 2008-08-22 2012-10-26 Anthrogenesis Corp Methods and compositions for treatment of bone defects with osteogenic placental adherent cells (OPACs)
US8858698B2 (en) * 2008-09-05 2014-10-14 Mentor Worldwide Llc Acellular matrix glue
US7927414B2 (en) * 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
NZ602455A (en) * 2008-11-19 2014-03-28 Anthrogenesis Corp Amnion derived adherent cells
BRPI0921999B8 (pt) * 2008-11-21 2021-05-25 Anthrogenesis Corp uso de uma quantidade terapeuticamente eficaz de células tronco placentárias
US9205177B2 (en) * 2009-03-04 2015-12-08 Peytant Solutions, Inc. Stents modified with material comprising amnion tissue and corresponding processes
PT2411506T (pt) 2009-03-25 2019-03-19 Celularity Inc Supressão de tumores usando células assassinas naturais intermédias derivadas de placenta humana e compostos imunomoduladores
US9039783B2 (en) * 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
WO2010141654A1 (en) 2009-06-05 2010-12-09 Anthrogenesis Corporation Improved method of collecting placental cells
AU2010266263B2 (en) 2009-07-02 2016-05-19 Celularity Inc. Method of producing erythrocytes without feeder cells
KR101103571B1 (ko) * 2009-09-23 2012-01-09 한림대학교 산학협력단 피부조직 재생용 구조체 및 이를 이용한 인공피부
WO2011050365A1 (en) 2009-10-23 2011-04-28 Forsight Labs, Llc Conformable therapeutic shield for vision and pain
US20130066283A1 (en) 2009-10-23 2013-03-14 Nexisvision, Inc. Corneal Denervation for Treatment of Ocular Pain
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
WO2011074208A1 (ja) * 2009-12-18 2011-06-23 国立大学法人東北大学 皮膚真皮又は羊膜透明化による角膜移植材料調製法
CA2787992A1 (en) 2010-01-26 2011-08-04 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells
EP3345998A1 (en) 2010-02-18 2018-07-11 Osiris Therapeutics, Inc. Immunocompatible chorionic membrane products
KR20200047797A (ko) 2010-04-07 2020-05-07 안트로제네시스 코포레이션 태반 줄기 세포를 사용한 혈관신생
CN102933221A (zh) 2010-04-08 2013-02-13 人类起源公司 使用胎盘干细胞治疗结节病
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8840665B2 (en) 2010-06-11 2014-09-23 Liventa Bioscience, Inc. Method of tendon repair with amnion and chorion constructs
WO2012003377A2 (en) * 2010-06-30 2012-01-05 Tissuetech, Inc. Methods of preparing chorion tissue and products derived therefrom
ES2759445T3 (es) * 2010-07-08 2020-05-11 Lifecell Corp Procedimiento de formación de matrices de tejido
KR20230096132A (ko) 2010-07-13 2023-06-29 셀룰래리티 인코포레이티드 천연 킬러 세포의 생성 방법
US20120035743A1 (en) * 2010-08-03 2012-02-09 AFcell Medical Amnion and chorion constructs and uses thereof in minimally invasive surgeries
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
WO2012088396A2 (en) * 2010-12-22 2012-06-28 University Of Florida Research Foundation, Inc. Multilayered implant materials derived from amniotic membrane, methods of making the multilayered implant materials, and method of using multilayered implant materials
US20120171180A1 (en) 2010-12-30 2012-07-05 Sascha Abramson Compositions comprising amnion derived adherent cells and platelet-rich plasma
WO2012092458A2 (en) 2010-12-30 2012-07-05 Anthrogenesis Corporation Compositions comprising placental stem cells and platelet rich plasma, and methods of use thereof
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
KR20140107103A (ko) 2011-02-14 2014-09-04 미메딕스 그룹 인크. 마이크로화된 태반 조직 조성물 및 이의 제조 및 사용 방법
WO2012112410A2 (en) * 2011-02-14 2012-08-23 Mimedx Group Inc. Micronized placental tissue compositions and methods for making and using the same
CA2826359A1 (en) * 2011-02-14 2012-08-23 Mimedx Group Inc. Tissue grafts modified with a cross-linking agent and methods of making and using the same
ES2707579T3 (es) 2011-06-01 2019-04-04 Celularity Inc Tratamiento del dolor usando citoblastos placentarios
ES2822301T3 (es) 2011-06-10 2021-04-30 Tissuetech Inc Métodos de procesamiento de tejidos de soporte fetal
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
US20130136773A1 (en) * 2011-09-30 2013-05-30 NuTech Spine, Inc. Expandable Placental Membrane and Methods of Making and Storing Same
US10517902B2 (en) * 2011-09-30 2019-12-31 Prime Merger Sub, Llc Expandable amnion membrane for treating non-healing wounds
US9585983B1 (en) * 2011-10-12 2017-03-07 BioDlogics, LLC Wound covering and method of preparation
EP2785360B1 (en) * 2011-12-02 2019-06-19 MIMEDX Group Inc. Placental tissue grafts produced by chemical dehydration/freeze-drying and methods for making and using same
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
EP2793745B1 (en) * 2011-12-22 2019-07-31 MIMEDX Group Inc. Cross-linked dehydrated placental tissue grafts and methods for making and using the same
CN113699105A (zh) * 2011-12-23 2021-11-26 人类起源公司 包含脱细胞并再群体化的胎盘血管支架的类器官
US9416410B2 (en) * 2012-02-14 2016-08-16 Genetics Development Corporation Cutoff point delta Ct. method for HER2 PCR testing in breast cancer
ES2666576T3 (es) * 2012-02-23 2018-05-07 Anthrogenesis Corporation Identificación de compuestos antitumorales usando placenta
US10071184B2 (en) * 2012-02-29 2018-09-11 Collagen Matrix, Inc. Collagen-coated tissue-based membranes
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US20180126033A9 (en) 2012-03-14 2018-05-10 MAM Holdings of West Florida, L.L.C. Collagen compositions and uses for biomaterial implants
US10576037B2 (en) * 2012-03-14 2020-03-03 MAM Holdings of West Florida, L.L.C. Compositions comprising placental collagen for use in wound healing
KR101404089B1 (ko) * 2012-04-02 2014-06-05 원광대학교산학협력단 양막 추출물을 함유하는 이중층 하이드로겔 습윤드레싱 및 그 제조방법
BR112015003149A2 (pt) 2012-08-13 2017-08-08 Anthrogenesis Corp células natural killer e usos das mesmas.
US9943551B2 (en) * 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US11338063B2 (en) * 2012-08-15 2022-05-24 Mimedx Group, Inc. Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
WO2014028657A1 (en) * 2012-08-15 2014-02-20 Mimedx Group, Inc Reinforced placental tissue grafts and methods of making and using the same
US8904664B2 (en) 2012-08-15 2014-12-09 Mimedx Group, Inc. Dehydration device and methods for drying biological materials
EP2892577B1 (en) * 2012-09-04 2019-01-30 Anthrogenesis Corporation Methods of tissue generation
US20150224226A1 (en) 2012-09-04 2015-08-13 Anthrogenesis Corporation Methods of tissue generation
DK2897625T3 (da) 2012-09-10 2019-12-16 Univ Wake Forest Health Sciences Amnionmembran og anvendelse deraf til sårheling og tissue engineering-konstrukter
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US8940684B2 (en) 2012-11-19 2015-01-27 Mimedx Group, Inc. Cross-linked collagen comprising an antifungal agent
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
RU2015127077A (ru) 2012-12-07 2017-01-12 Антродженезис Корпорейшн Лечение поражений полости рта при помощи внеклеточного матрикса плаценты
US20150307879A1 (en) 2012-12-14 2015-10-29 Anthrogenesis Corporation Anoikis resistant placental stem cells and uses thereof
AU2013204922B2 (en) 2012-12-20 2015-05-14 Celgene Corporation Chimeric antigen receptors
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
CN103006349A (zh) * 2012-12-26 2013-04-03 天津市赛宁生物工程技术有限公司 体外培养的组织工程血管
CN105246495B (zh) * 2013-01-09 2021-08-10 Ise专业检测与咨询服务有限公司 来自非哺乳动物组织的脱细胞化的生物材料
US9655948B1 (en) 2013-01-17 2017-05-23 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9827293B2 (en) 2013-01-17 2017-11-28 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US10517931B2 (en) 2013-01-17 2019-12-31 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
JP6545102B2 (ja) 2013-01-18 2019-07-17 ミメディクス グループ インコーポレイテッド 心病態を治療する方法
US10905800B1 (en) 2013-01-29 2021-02-02 BioDlogics, LLC Ocular covering and method of use
WO2014120946A1 (en) * 2013-01-30 2014-08-07 NuTech Medical, Inc. Placental membrane preparation and methods of making and using same
CN103127549A (zh) * 2013-02-01 2013-06-05 中山大学中山眼科中心 一种脱细胞睑板及其制备方法
EP3622960A1 (en) 2013-02-05 2020-03-18 Celularity, Inc. Natural killer cells from placenta
US9498327B1 (en) 2013-03-05 2016-11-22 Biodlogics Llc Repair of tympanic membrane using human birth tissue material
US9789138B1 (en) 2013-03-06 2017-10-17 BioDlogics, LLC Neural repair construct and method of use
US9770472B1 (en) 2013-03-08 2017-09-26 Brahm Holdings, Llc Organ jacket and methods of use
US9855301B1 (en) 2013-03-13 2018-01-02 Biodlogics Llc Human birth tissue laminate and methods of use
WO2014164900A1 (en) 2013-03-13 2014-10-09 Allosource Fascia fibrous compositions and methods for their use and manufacture
WO2014159806A1 (en) 2013-03-14 2014-10-02 Anthrogenesis Corporation Enhanced placental stem cells and uses thereof
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
NO2975611T3 (pt) 2013-03-15 2018-06-09
JP6123018B2 (ja) 2013-03-15 2017-04-26 ニューテック メディカル インコーポレイテッド 胎盤物質由来の製剤並びにその製造方法及び使用方法
US9795638B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Cardiothoracic construct and methods of use
CN104083803B (zh) * 2013-04-01 2016-04-27 陕西佰傲再生医学有限公司 一种用于眼表修复的生物膜及其制备方法
US10335433B2 (en) 2013-04-10 2019-07-02 Mimedx Group, Inc. NDGA polymers and metal complexes thereof
AU2014268778B2 (en) * 2013-05-20 2018-09-20 Yale University Anti-thrombogenic grafts
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
AU2014302772A1 (en) 2013-06-24 2016-01-28 Celularity Inc. Extracellular matrix composition beads for cell culture
JP6310072B2 (ja) 2013-06-26 2018-04-11 ネクシスビジョン, インコーポレイテッド 屈折矯正のためのコンタクトレンズ
US10449220B2 (en) 2013-08-30 2019-10-22 Mimedx Group, Inc. Micronized placental compositions comprising a chelator
EP2857350A1 (en) * 2013-09-10 2015-04-08 ESPCI Innov Use of nanoparticles for gluing gels
KR102161901B1 (ko) * 2013-12-06 2020-10-05 알로소스 조직의 시트를 건조하는 방법
AU2015206236B2 (en) 2014-01-17 2020-02-20 Mimedx Group, Inc. Method for inducing angiogenesis
WO2015120405A1 (en) * 2014-02-07 2015-08-13 Amniolife Corporation Patterned tissue membranes and methods and system for their preparation
US10894066B2 (en) 2014-03-06 2021-01-19 Amnio Technology Llc Amnion derived therapeutic compositions and methods of use
US9132156B1 (en) * 2014-06-15 2015-09-15 Amnio Technology Llc Acellular amnion derived therapeutic compositions
US9801910B2 (en) * 2014-03-17 2017-10-31 Ethicon, Inc. Decellularized pleural matrix
CN103861151B (zh) * 2014-03-27 2016-03-30 成都青山利康药业有限公司 一种脱细胞胎盘基质材料的制备方法
AU2014393404A1 (en) * 2014-05-07 2016-11-24 Osiris Therapeutics, Inc. Immunocompatible amniotic membrane products
EP3139935A4 (en) * 2014-05-07 2017-11-15 Osiris Therapeutics, Inc. Therapeutic placental compositions, methods of making and methods of use
WO2015175776A1 (en) 2014-05-14 2015-11-19 NuTech Medical, Inc. Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs
US10174289B2 (en) 2014-05-28 2019-01-08 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
US10363278B2 (en) 2014-06-15 2019-07-30 Amnio Technology Llc Frozen therapeutic dose and package
EP2979710B8 (en) * 2014-07-29 2020-07-15 National Cheng Kung University Cell tissue gel containing collagen and hyaluronan
WO2016033385A1 (en) * 2014-08-28 2016-03-03 Mimedx Group, Inc. Collagen reinforced tissue grafts
US10179191B2 (en) 2014-10-09 2019-01-15 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
MX2017004348A (es) * 2014-10-10 2017-07-04 Orthocell Ltd Reparacion sin sutura de tejidos blandos.
WO2016061464A1 (en) 2014-10-17 2016-04-21 Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intetine using pluripotent stem cells and methods of making and using same
US10265438B1 (en) 2014-11-03 2019-04-23 BioDlogics, LLC Methods and compositions for the repair and replacement of connective tissue
US10765705B2 (en) 2014-11-24 2020-09-08 Prime Merger Sub, Llc Visco-supplement compositions, and methods of use thereof
JP6797803B2 (ja) 2014-12-31 2020-12-09 セルジーン コーポレイション ナチュラルキラー細胞を用いて血液障害、固形腫瘍、又は感染性疾患を治療する方法
WO2016111899A1 (en) 2015-01-05 2016-07-14 Petrucci Gary M Methods and materials for treating lung disorders
US10736990B2 (en) 2015-02-11 2020-08-11 Mimedx Group, Inc. Collagen and micronized placental tissue compositions and methods of making and using the same
WO2016138025A2 (en) 2015-02-23 2016-09-01 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
US11028362B2 (en) * 2015-04-17 2021-06-08 The Regents Of The University Of California Decellularized human amniotic membrane for cell delivery, cell culture and inflammation prevention
CN104826166B (zh) * 2015-05-06 2017-06-06 广州优适清生物科技有限公司 一种用于青光眼治疗的生物膜及其制备方法
CN107847526A (zh) 2015-05-20 2018-03-27 组织技术公司 用于预防上皮细胞的增殖和上皮‑间充质转换的组合物和方法
US10531957B2 (en) 2015-05-21 2020-01-14 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
CN105169493B (zh) * 2015-07-13 2018-02-27 江南大学 一种人工异种皮肤的制备方法
US10517903B2 (en) 2015-09-14 2019-12-31 Amnio Technology Llc Amnion derived therapeutic composition and process of making same
CN108367028A (zh) 2015-09-15 2018-08-03 细胞结构公司 使用胎盘细胞治疗糖尿病性周围神经病变
CA2999909A1 (en) 2015-09-23 2017-03-30 Osiris Therapeutics, Inc. Umbilical tissue compositions and methods of use
WO2017059089A1 (en) * 2015-09-29 2017-04-06 Anicell Biotech, Llc Methods and articles of manufacture for the treatment of animals
EP3367966A4 (en) 2015-10-30 2019-07-10 New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special Surgery SUSPENDED PATH AND METHOD FOR ADMINISTRATION WITHIN AN EXISTING ARTHROSCOPIC WORKFLOW
US20170136070A1 (en) * 2015-11-18 2017-05-18 Dregalla Patent Holdco, LLC Acellular Regenerative Products and Methods of Their Manufacture
US11207446B2 (en) 2015-12-23 2021-12-28 Lifenet Health Decellularized placental membrane and methods of preparing and use thereof
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US11484401B2 (en) 2016-02-01 2022-11-01 Medos International Sarl Tissue augmentation scaffolds for use in soft tissue fixation repair
US10702260B2 (en) 2016-02-01 2020-07-07 Medos International Sàrl Soft tissue fixation repair methods using tissue augmentation scaffolds
WO2017136557A1 (en) 2016-02-05 2017-08-10 Petrucci Gary M Methods and materials for treating nerve injuries and neurological disorders
US11066650B2 (en) 2016-05-05 2021-07-20 Children's Hospital Medical Center Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same
CN105833353B (zh) * 2016-05-09 2018-04-20 拜欧迪赛尔(北京)生物科技有限公司 一种生物工程脱细胞真皮基质的制备及用途
AU2017316682B2 (en) 2016-08-24 2020-10-15 Arthrex, Inc. Tissue use for repair of injury
SG11201903899VA (en) * 2016-11-02 2019-05-30 Axogen Corp Amnion tissue grafts and methods of preparing and using same
CN106390195B (zh) * 2016-11-16 2019-08-23 四川大学 一种胶原膜的改性方法
US20190314424A1 (en) 2016-12-05 2019-10-17 Celularity, Inc. Treatment of lymphedema and related conditions using placental adherent cells
AU2017373767B2 (en) 2016-12-05 2021-09-16 Children's Hospital Medical Center Colonic organoids and methods of making and using same
CN108210995A (zh) * 2016-12-14 2018-06-29 成都青山利康药业有限公司 一种新型的复合生物组织修复材料及其制备方法和用途
WO2018137041A1 (en) * 2017-01-26 2018-08-02 Dalhousie University Templated assembly of collagen fibers and uses thereof
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
US20200023014A1 (en) * 2017-02-03 2020-01-23 Biocellix Spa Collagen membrane or matrix with antimicrobial properties
CN107137768B (zh) * 2017-04-12 2020-07-07 苏州诺普再生医学有限公司 一种脱细胞羊膜粉的制备方法
JP7031138B2 (ja) 2017-05-11 2022-03-08 株式会社リコー 脱細胞化組織の製造方法、及び脱細胞化組織の製造装置
CN107233144A (zh) * 2017-05-31 2017-10-10 中山大学中山眼科中心 去细胞角膜基质透镜在治疗眼科疾病中的应用
US10478531B2 (en) 2017-06-22 2019-11-19 Gary M. Petrucci Methods and materials for treating blood vessels
CN109481737B (zh) * 2017-09-12 2021-07-06 中国人民解放军第三军医大学第一附属医院 一种仿生双层敷料及其制备方法
US10251917B1 (en) 2017-09-19 2019-04-09 Gary M. Petrucci Methods and materials for treating tumors
WO2019067792A1 (en) 2017-09-28 2019-04-04 Celularity, Inc. TUMOR CONTROL WITH INTERMEDIATE NATURAL KILLER CELLS DERIVED FROM HUMAN PLACENTA (PINK) IN COMBINATION WITH ANTIBODY
US10575516B2 (en) 2017-11-14 2020-03-03 Cook Biotech Incorporated Preserved tissue products and related methods
CN108051509B (zh) * 2017-11-21 2020-06-23 陈溉 一种治疗褥疮的药物的特征图谱检测方法及其应用
CN107929811A (zh) * 2017-12-15 2018-04-20 厦门大学 一种组织工程角膜
WO2019165320A1 (en) 2018-02-22 2019-08-29 Celularity, Inc. Post partum tissue-derived induced pluripotent stem cells and uses thereof
US11602548B1 (en) 2018-02-26 2023-03-14 Convatec, Inc Fibrous birth tissue composition and method of use
CN109065670B (zh) * 2018-08-08 2019-12-20 长春长光宇航复合材料有限公司 碳纤维复合材料网格蒙皮太阳能电池阵基板的制备方法
WO2020113182A1 (en) 2018-11-30 2020-06-04 Celularity, Inc. Expansion of natural killer cells and ilc3 cells with novel aromatic compounds
CN109557107A (zh) * 2018-12-29 2019-04-02 南工大溧阳新材料研发中心有限公司 一种不锈钢/碳钢复合材料的探伤检测方法
US11511017B2 (en) 2019-03-12 2022-11-29 Arthrex, Inc. Ligament reconstruction
US20220265712A1 (en) 2019-06-14 2022-08-25 Celularity Inc. Populations of natural killer cells for treating cancers
WO2021016621A1 (en) 2019-07-25 2021-01-28 Celularity Inc. Populations of natural killer cells comprising a cd38 chimeric antigen receptor
US20230355759A1 (en) 2019-07-31 2023-11-09 Celularity Inc. Populations of natural killer cells comprising a cleavage resistant cd16
CN110404119B (zh) * 2019-08-29 2023-04-07 上海越增生物科技有限公司 羊膜组织工程去免疫原皮肤支架的制备方法
WO2021113849A1 (en) 2019-12-05 2021-06-10 Celularity Inc. Her2+ cancer treatment with populations of natural killer cells comprising a cleavage resistant cd16
WO2021155312A1 (en) 2020-01-29 2021-08-05 Celularity Inc. Placental derived natural killer cells for treatment of coronavirus infections
US20210244845A1 (en) * 2020-02-10 2021-08-12 Leslie MARCELIN Method Of Processing Amnion To Form A Suture
EP4104863A4 (en) 2020-02-14 2024-02-21 Kheiros Pater Inovacao S A METHOD FOR PRODUCING DECELLULARIZED BIOMATERIAL, DECELLULARIZED BIOMATERIAL AND USE THEREOF
WO2021203045A1 (en) * 2020-04-03 2021-10-07 Tissuetech, Inc. Methods of using umbilical cord products for treatment of ocular surface disorders
US20230210909A1 (en) 2020-05-08 2023-07-06 Celularity Inc. Placenta-derived adherent (pda) stem cell for the treatment of adults with sars-cov-2 related acute respiratory failure and ards (covid-19)
TW202233828A (zh) 2020-11-12 2022-09-01 日商Adeka股份有限公司 去細胞化組織組成物
CN112641999B (zh) * 2020-12-04 2022-10-04 陕西佰傲再生医学有限公司 一种铺膜设备及其应用
KR20230118861A (ko) * 2020-12-11 2023-08-14 오스테오지닉스 바이오메디칼, 인크. 다중-층 콜라겐-기반 막
JP2024515581A (ja) * 2021-04-13 2024-04-10 セルラリティ インク. 多層羊膜組織移植片及びその使用
WO2023278628A1 (en) 2021-06-29 2023-01-05 Celularity Inc. Human placental hematopoietic stem cell derived natural killer cells in acute myeloid leukemia (aml) remission with minimal residual disease (mrd) or relapsed/refractory aml
WO2023010123A1 (en) 2021-07-29 2023-02-02 Celularity Inc. Placenta-dervied nk cells as a senolytic for therapeutic and other uses
CN114028618A (zh) * 2021-10-25 2022-02-11 广东普洛宇飞生物科技有限公司 一种基于羊膜基底膜的生物材料及其制备方法和应用
WO2023137344A1 (en) 2022-01-11 2023-07-20 Celularity Inc. Cleavage resistant cd16 constructs and uses thereof
CN115054730B (zh) * 2022-06-14 2023-08-18 健诺维(成都)生物科技有限公司 一种羊膜新材料及其制备方法

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157524A (en) * 1960-10-25 1964-11-17 Ethicon Inc Preparation of collagen sponge
US3800792A (en) 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
DE2416313C3 (de) 1974-04-04 1978-11-23 Roland 8731 Euerdorf Satzinger Sicherheitseinrichtung für die Insassen von Fahrzeugen, insbesondere Kraftfahrzeugen
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
DE2943520C2 (de) 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
US4446234A (en) * 1981-10-23 1984-05-01 The United States Of America As Represented By The Department Of Health And Human Services Vitro cellular interaction with amnion membrane substrate
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4883618A (en) 1983-02-02 1989-11-28 Minnesota Mining And Manufacturing Company Absorbable nerve repair device and method
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4778467A (en) 1984-04-25 1988-10-18 The University Of Utah Prostheses and methods for promoting nerve regeneration and for inhibiting the formation of neuromas
IL78950A (en) * 1985-06-06 1991-12-15 Univ Jefferson Coating for prosthetic devices
JPS63260549A (ja) * 1987-04-17 1988-10-27 石川 統一 補綴材料およびその製造方法
EP0363400B1 (en) 1987-04-28 1993-03-03 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
US5036056A (en) * 1987-07-08 1991-07-30 Martin Kludas Methods for treating damaged corneal, uterine, or cartilage tissue
GB8803697D0 (en) * 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US5116620A (en) 1989-11-21 1992-05-26 Bruce A. Barber Antimicrobial wound dressing
US5308627A (en) 1990-08-07 1994-05-03 Umbdenstock Jr Anthony J Nutritional supplement for optimizing cellular health
US5198465A (en) 1991-06-19 1993-03-30 Dioguardi Francesco S Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen
EP0534152B1 (en) 1991-09-26 1996-11-06 United States Surgical Corporation Nerve repair device
US5418875A (en) 1992-09-04 1995-05-23 Honda Tsushin Kogyo Co., Ltd. Adapter for optical connector having float-type sleeve holder and panel fitting for mounting the same
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
JP3542170B2 (ja) * 1993-08-06 2004-07-14 株式会社アムニオテック 医用材料及びその製造方法
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
IL112580A0 (en) * 1994-02-24 1995-05-26 Res Dev Foundation Amniotic membrane graft of wrap to prevent adhesions or bleeding of internal organs
US6203755B1 (en) * 1994-03-04 2001-03-20 St. Jude Medical, Inc. Electron beam sterilization of biological tissues
AU1931495A (en) * 1994-03-14 1995-10-03 Cryolife, Inc. Treated tissue for implantation and preparation methods
JP2905718B2 (ja) * 1995-03-31 1999-06-14 東洋紡績株式会社 医用材料およびその製造方法
CA2173508A1 (en) 1995-03-31 1996-10-01 Tooru Yui Medical device and method for producing the same
JPH09122227A (ja) 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料およびその製造方法
JP3476631B2 (ja) * 1995-12-21 2003-12-10 株式会社アムニオテック ヒト由来の天然コラーゲン膜からなる医用材料
EP0907721A1 (en) * 1996-05-28 1999-04-14 Brown University Research Foundation Hyaluronan based biodegradable scaffolds for tissue repair
JP3563216B2 (ja) * 1996-10-14 2004-09-08 株式会社アムニオテック 医用代替膜及びその製造方法
US5804594A (en) 1997-01-22 1998-09-08 Murad; Howard Pharmaceutical compositions and methods for improving wrinkles and other skin conditions
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US5993844A (en) * 1997-05-08 1999-11-30 Organogenesis, Inc. Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix
US5932205A (en) * 1997-07-24 1999-08-03 Wang; Ming X. Biochemical contact lens for treating photoablated corneal tissue
US6143315A (en) * 1997-07-24 2000-11-07 Wang; Ming X. Biochemical contact lens for treating injured corneal tissue
US6371992B1 (en) * 1997-12-19 2002-04-16 The Regents Of The University Of California Acellular matrix grafts: preparation and use
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
US6734018B2 (en) * 1999-06-07 2004-05-11 Lifenet Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced
US6312474B1 (en) * 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6432712B1 (en) * 1999-11-22 2002-08-13 Bioscience Consultants, Llc Transplantable recellularized and reendothelialized vascular tissue graft
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
US6376244B1 (en) * 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
US6428802B1 (en) * 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
AU2001284968B2 (en) * 2000-08-16 2006-12-21 Duke University Decellularized tissue engineered constructs and tissues
MXPA03002414A (es) * 2000-09-18 2004-07-08 Organogenesis Inc Protesis con injerto de hoja plana tratada por bioingenieria y su uso.
WO2003032735A1 (en) * 2001-10-18 2003-04-24 Lifecell Corporation Remodeling of tissues and organs
US7497602B2 (en) 2007-02-08 2009-03-03 Wen-Cheng Lien Three dimension collapsible lampshade

Also Published As

Publication number Publication date
EP2702871A1 (en) 2014-03-05
AU2011201662B2 (en) 2013-02-07
EP2702871B1 (en) 2018-10-24
ZA200407650B (en) 2006-07-26
AU2008202604B2 (en) 2011-01-06
JP5931327B2 (ja) 2016-06-08
EP3412322A1 (en) 2018-12-12
KR20050002906A (ko) 2005-01-10
US20040048796A1 (en) 2004-03-11
JP2014138590A (ja) 2014-07-31
WO2003082201A3 (en) 2005-11-10
JP2006507851A (ja) 2006-03-09
HK1085384A1 (en) 2006-08-25
IL164220A0 (en) 2005-12-18
ES2710024T3 (es) 2019-04-22
CA2479903A1 (en) 2003-10-09
KR100999247B1 (ko) 2010-12-07
MXPA04009188A (es) 2005-06-20
EP1575572B1 (en) 2014-09-24
EP1575572A2 (en) 2005-09-21
AU2003226018A1 (en) 2003-10-13
JP4615223B2 (ja) 2011-01-19
DK2702871T3 (en) 2019-02-18
AU2011201662A1 (en) 2011-05-12
AU2008202604A1 (en) 2008-07-03
ES2526088T3 (es) 2015-01-05
EP1575572A4 (en) 2010-10-13
JP5993387B2 (ja) 2016-09-14
WO2003082201A2 (en) 2003-10-09
DK2700309T3 (da) 2019-09-16
US20030187515A1 (en) 2003-10-02
CN1791331A (zh) 2006-06-21
NZ535799A (en) 2010-06-25
AU2003226018B2 (en) 2008-03-13
JP2010265298A (ja) 2010-11-25
CA2479903C (en) 2016-08-23
EP2700309A1 (en) 2014-02-26
EP2700309B1 (en) 2019-06-05
IL164220A (en) 2012-10-31

Similar Documents

Publication Publication Date Title
PT2702871T (pt) Biotecido de colagénio e sua utilização
EP1539941A4 (en) ADZYMES AND THEIR USES
HK1079995A1 (zh) 修飾的脫唾液酸-干擾素系及其應用
EP1551384A4 (en) R-NSAID ESTERS AND ITS USE
HK1088837A1 (en) Clk-peptide and slk-peptide
AU2003240939A8 (en) Electroprocessed collagen and tissue engineering
GB0220214D0 (en) Compounds and their use
SI1551805T1 (sl) Substituirani gama-fenil-delta-laktami in njihova uporaba
AU2003296369A8 (en) Imminoamines and preparation thereof
AU2003215257A8 (en) Modified defensins and their use
IL165112A0 (en) Variant integrinpolypeptides and thereof
GB0200941D0 (en) Laryngoscopes and parts thereof
AU2003231827A8 (en) Pseudo-tissues and uses thereof
GB0318546D0 (en) Quinoxalinones and their use
GB0227906D0 (en) Compounds and their use
AU2003302173A8 (en) Spirotetrathiocarbamates and spirooxothiocarbamates
EP1577322A4 (en) NEW PROTEINS AND THEIR USE
EP1541677A4 (en) NEW PROTEINS AND USE THEREOF
GB0230134D0 (en) Compounds and their use
AU2003228397A8 (en) Hausp-p53 interaction and uses thereof
AU2003216442A8 (en) Enkurin and uses thereof
GB0218031D0 (en) Compounds and their use
GB0230281D0 (en) Compounds and their use
EP1499338A4 (en) 7-HYDROXY-16ALPHA-FLUORO-5-ANDROSENES-17-ONE AND 7-HYDROXY-16ALPHA-FLUORO-5-ANDROSTAN-17-ONE AND THEIR DERIVATIVES
GB0220215D0 (en) Compounds and their use