PT2601214T - Composições de antagonistas de vegf e utilizações destes - Google Patents
Composições de antagonistas de vegf e utilizações destesInfo
- Publication number
- PT2601214T PT2601214T PT117458703T PT11745870T PT2601214T PT 2601214 T PT2601214 T PT 2601214T PT 117458703 T PT117458703 T PT 117458703T PT 11745870 T PT11745870 T PT 11745870T PT 2601214 T PT2601214 T PT 2601214T
- Authority
- PT
- Portugal
- Prior art keywords
- vegf antagonist
- antagonist compositions
- compositions
- vegf
- antagonist
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/10—Protein-tyrosine kinases (2.7.10)
- C12Y207/10001—Receptor protein-tyrosine kinase (2.7.10.1)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37154610P | 2010-08-06 | 2010-08-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2601214T true PT2601214T (pt) | 2017-12-20 |
Family
ID=44630479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT117458703T PT2601214T (pt) | 2010-08-06 | 2011-08-05 | Composições de antagonistas de vegf e utilizações destes |
Country Status (12)
Country | Link |
---|---|
US (2) | US9441029B2 (pt) |
EP (2) | EP2601214B1 (pt) |
CY (1) | CY1121111T1 (pt) |
DK (1) | DK2601214T3 (pt) |
ES (1) | ES2652508T3 (pt) |
HR (1) | HRP20180154T1 (pt) |
HU (1) | HUE035554T2 (pt) |
LT (1) | LT2601214T (pt) |
PL (1) | PL2601214T3 (pt) |
PT (1) | PT2601214T (pt) |
SI (1) | SI2601214T1 (pt) |
WO (1) | WO2012019128A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108697792A (zh) * | 2015-11-19 | 2018-10-23 | 珠海泰瑞尚生物医药科技有限公司 | 用于结合vegf的方法和组合物 |
AU2019212622A1 (en) | 2018-01-26 | 2020-08-13 | The Regents Of The University Of California | Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents |
MX2022006241A (es) | 2019-11-25 | 2022-08-22 | Univ California | Inhibidores de vegf de accion prolongada para la neovascularizacion intraocular. |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5336603A (en) | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
US4847325A (en) * | 1988-01-20 | 1989-07-11 | Cetus Corporation | Conjugation of polymer to colony stimulating factor-1 |
EP1762623A1 (en) | 1988-01-22 | 2007-03-14 | ZymoGenetics, Inc. | Methods for producing biologically active peptide dimers |
US5567584A (en) | 1988-01-22 | 1996-10-22 | Zymogenetics, Inc. | Methods of using biologically active dimerized polypeptide fusions to detect PDGF |
US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
JPH03233530A (ja) | 1990-02-09 | 1991-10-17 | Fuji Photo Optical Co Ltd | カメラ |
US20020032313A1 (en) | 1991-03-29 | 2002-03-14 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
EP1975181B1 (en) | 1992-10-28 | 2011-02-16 | Genentech, Inc. | Use of vascular endothelial cell growth factor antagonists |
FR2702152B1 (fr) | 1993-03-03 | 1995-05-24 | Inst Nat Sante Rech Med | Virus recombinants et leur utilisation en thérapie génique. |
EP0694042B1 (en) | 1993-03-25 | 2004-11-03 | Merck & Co. Inc. | Inhibitor of vascular endothelial cell growth factor |
US6686200B1 (en) | 1993-08-31 | 2004-02-03 | Uab Research Foundation | Methods and compositions for the large scale production of recombinant adeno-associated virus |
US5827702A (en) | 1994-10-31 | 1998-10-27 | Genentech, Inc. | Ocular gene therapy |
JPH09154588A (ja) | 1995-10-07 | 1997-06-17 | Toagosei Co Ltd | Vegf結合性ポリペプチド |
US6100071A (en) | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
WO1998013071A1 (en) | 1996-09-24 | 1998-04-02 | Merck & Co., Inc. | Gene therapy for inhibition of angiogenesis |
JP3837748B2 (ja) | 1997-01-17 | 2006-10-25 | 東亞合成株式会社 | Vegf結合性ポリペプチド |
WO1998051323A1 (en) | 1997-05-13 | 1998-11-19 | The Regents Of The University Of California | Novel antiangiogenic peptide agents and their therapeutic and diagnostic use |
EP1007714B1 (en) | 1997-06-03 | 2005-12-14 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Regulatory sequences capable of conferring expression of a heterologous dna sequence in endothelial cells in vivo and uses thereof |
CA2293723A1 (en) | 1997-06-18 | 1998-12-23 | Merck & Co., Inc. | Human receptor tyrosine kinase, kdr |
AU9319198A (en) | 1997-09-19 | 1999-04-05 | Trustees Of The University Of Pennsylvania, The | Methods and vector constructs useful for production of recombinant aav |
US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
US7083950B2 (en) | 1998-09-25 | 2006-08-01 | Regeneron Pharmaceuticals, Inc. | High affinity fusion proteins and therapeutic and diagnostic methods for use |
US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
CA2367375A1 (en) | 1999-03-15 | 2000-09-21 | Chiron Corporation | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
US7070959B1 (en) | 1999-06-08 | 2006-07-04 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
UA74146C2 (uk) | 1999-06-08 | 2005-11-15 | Редженерон Фармасьютікалс, Інк. | Модифікований хімеричний поліпептид з покращеними фармакокінетичними властивостями |
US6821775B1 (en) | 2000-02-11 | 2004-11-23 | Genvec, Inc. | Viral vector encoding pigment epithelium-derived factor |
WO2002024234A2 (en) | 2000-09-20 | 2002-03-28 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
KR100983997B1 (ko) | 2001-01-09 | 2010-09-28 | 메르크 파텐트 게엠베하 | 수용체 타이로신 키나아제 저해제 및 혈관형성 저해제를 사용하는 병용 요법 |
EP1490113A4 (en) | 2002-03-20 | 2007-05-02 | Univ Florida | ADENO-ASSOCIATED RECOMBINANT VIRAL VECTOR (RAAV) COMPOSITIONS AND CORRESPONDING METHODS FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION |
CU23178A1 (es) | 2002-04-15 | 2006-09-22 | Ct Ingenieria Genetica Biotech | INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA |
DE60336555D1 (de) | 2002-06-21 | 2011-05-12 | Novo Nordisk Healthcare Ag | Pegylierte glykoformen von faktor vii |
WO2004085478A2 (en) | 2003-03-26 | 2004-10-07 | Apogenix Gmbh | Improved fc fusion proteins |
US20060198819A1 (en) | 2003-08-08 | 2006-09-07 | Novo Nordisk Healthcare A/G | Use of galactose oxidase for selective chemical conjugation of protractor molecules to proteins of therapeutic interest |
JP4944032B2 (ja) * | 2004-09-13 | 2012-05-30 | ジェンザイム・コーポレーション | 多量体構築物 |
JP2008524241A (ja) | 2004-12-17 | 2008-07-10 | ジェネンテック・インコーポレーテッド | 従来の治療の効果がなかった患者の自己免疫性疾患の血管新生阻害治療 |
WO2010019263A2 (en) * | 2008-08-15 | 2010-02-18 | Genzyme Corporation | Soluble flt constructs for treating cancers |
-
2011
- 2011-08-05 WO PCT/US2011/046802 patent/WO2012019128A1/en active Application Filing
- 2011-08-05 PT PT117458703T patent/PT2601214T/pt unknown
- 2011-08-05 DK DK11745870.3T patent/DK2601214T3/en active
- 2011-08-05 PL PL11745870T patent/PL2601214T3/pl unknown
- 2011-08-05 ES ES11745870.3T patent/ES2652508T3/es active Active
- 2011-08-05 LT LTEP11745870.3T patent/LT2601214T/lt unknown
- 2011-08-05 HU HUE11745870A patent/HUE035554T2/en unknown
- 2011-08-05 SI SI201131407T patent/SI2601214T1/en unknown
- 2011-08-05 EP EP11745870.3A patent/EP2601214B1/en active Active
- 2011-08-05 EP EP17198701.9A patent/EP3327032A1/en active Pending
- 2011-08-05 US US13/814,182 patent/US9441029B2/en active Active
-
2016
- 2016-07-25 US US15/218,667 patent/US10308917B2/en active Active
-
2018
- 2018-01-26 HR HRP20180154TT patent/HRP20180154T1/hr unknown
- 2018-01-31 CY CY181100113T patent/CY1121111T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20180154T1 (hr) | 2018-03-09 |
SI2601214T1 (en) | 2018-03-30 |
CY1121111T1 (el) | 2019-12-11 |
WO2012019128A1 (en) | 2012-02-09 |
US10308917B2 (en) | 2019-06-04 |
LT2601214T (lt) | 2018-02-26 |
DK2601214T3 (en) | 2018-02-05 |
US20160326501A1 (en) | 2016-11-10 |
PL2601214T3 (pl) | 2018-05-30 |
ES2652508T3 (es) | 2018-02-02 |
EP2601214A1 (en) | 2013-06-12 |
US20130324465A1 (en) | 2013-12-05 |
EP2601214B1 (en) | 2017-11-01 |
US9441029B2 (en) | 2016-09-13 |
HUE035554T2 (en) | 2018-05-02 |
EP3327032A1 (en) | 2018-05-30 |
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