PT2601214T - Composições de antagonistas de vegf e utilizações destes - Google Patents

Composições de antagonistas de vegf e utilizações destes

Info

Publication number
PT2601214T
PT2601214T PT117458703T PT11745870T PT2601214T PT 2601214 T PT2601214 T PT 2601214T PT 117458703 T PT117458703 T PT 117458703T PT 11745870 T PT11745870 T PT 11745870T PT 2601214 T PT2601214 T PT 2601214T
Authority
PT
Portugal
Prior art keywords
vegf antagonist
antagonist compositions
compositions
vegf
antagonist
Prior art date
Application number
PT117458703T
Other languages
English (en)
Inventor
Stefano James
Pan Clark
Qiu Huawei
O'callaghan Michael
Matthews Gloria
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of PT2601214T publication Critical patent/PT2601214T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/10Protein-tyrosine kinases (2.7.10)
    • C12Y207/10001Receptor protein-tyrosine kinase (2.7.10.1)
PT117458703T 2010-08-06 2011-08-05 Composições de antagonistas de vegf e utilizações destes PT2601214T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37154610P 2010-08-06 2010-08-06

Publications (1)

Publication Number Publication Date
PT2601214T true PT2601214T (pt) 2017-12-20

Family

ID=44630479

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117458703T PT2601214T (pt) 2010-08-06 2011-08-05 Composições de antagonistas de vegf e utilizações destes

Country Status (12)

Country Link
US (2) US9441029B2 (pt)
EP (2) EP2601214B1 (pt)
CY (1) CY1121111T1 (pt)
DK (1) DK2601214T3 (pt)
ES (1) ES2652508T3 (pt)
HR (1) HRP20180154T1 (pt)
HU (1) HUE035554T2 (pt)
LT (1) LT2601214T (pt)
PL (1) PL2601214T3 (pt)
PT (1) PT2601214T (pt)
SI (1) SI2601214T1 (pt)
WO (1) WO2012019128A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108697792A (zh) * 2015-11-19 2018-10-23 珠海泰瑞尚生物医药科技有限公司 用于结合vegf的方法和组合物
AU2019212622A1 (en) 2018-01-26 2020-08-13 The Regents Of The University Of California Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents
MX2022006241A (es) 2019-11-25 2022-08-22 Univ California Inhibidores de vegf de accion prolongada para la neovascularizacion intraocular.

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EP1762623A1 (en) 1988-01-22 2007-03-14 ZymoGenetics, Inc. Methods for producing biologically active peptide dimers
US5567584A (en) 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
US5116964A (en) 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
JPH03233530A (ja) 1990-02-09 1991-10-17 Fuji Photo Optical Co Ltd カメラ
US20020032313A1 (en) 1991-03-29 2002-03-14 Genentech, Inc. Vascular endothelial cell growth factor antagonists
EP1975181B1 (en) 1992-10-28 2011-02-16 Genentech, Inc. Use of vascular endothelial cell growth factor antagonists
FR2702152B1 (fr) 1993-03-03 1995-05-24 Inst Nat Sante Rech Med Virus recombinants et leur utilisation en thérapie génique.
EP0694042B1 (en) 1993-03-25 2004-11-03 Merck & Co. Inc. Inhibitor of vascular endothelial cell growth factor
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US5827702A (en) 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
JPH09154588A (ja) 1995-10-07 1997-06-17 Toagosei Co Ltd Vegf結合性ポリペプチド
US6100071A (en) 1996-05-07 2000-08-08 Genentech, Inc. Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
WO1998013071A1 (en) 1996-09-24 1998-04-02 Merck & Co., Inc. Gene therapy for inhibition of angiogenesis
JP3837748B2 (ja) 1997-01-17 2006-10-25 東亞合成株式会社 Vegf結合性ポリペプチド
WO1998051323A1 (en) 1997-05-13 1998-11-19 The Regents Of The University Of California Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
EP1007714B1 (en) 1997-06-03 2005-12-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Regulatory sequences capable of conferring expression of a heterologous dna sequence in endothelial cells in vivo and uses thereof
CA2293723A1 (en) 1997-06-18 1998-12-23 Merck & Co., Inc. Human receptor tyrosine kinase, kdr
AU9319198A (en) 1997-09-19 1999-04-05 Trustees Of The University Of Pennsylvania, The Methods and vector constructs useful for production of recombinant aav
US6378526B1 (en) 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
US7083950B2 (en) 1998-09-25 2006-08-01 Regeneron Pharmaceuticals, Inc. High affinity fusion proteins and therapeutic and diagnostic methods for use
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CA2367375A1 (en) 1999-03-15 2000-09-21 Chiron Corporation Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US7070959B1 (en) 1999-06-08 2006-07-04 Regeneron Pharmaceuticals, Inc. Modified chimeric polypeptides with improved pharmacokinetic properties
UA74146C2 (uk) 1999-06-08 2005-11-15 Редженерон Фармасьютікалс, Інк. Модифікований хімеричний поліпептид з покращеними фармакокінетичними властивостями
US6821775B1 (en) 2000-02-11 2004-11-23 Genvec, Inc. Viral vector encoding pigment epithelium-derived factor
WO2002024234A2 (en) 2000-09-20 2002-03-28 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
KR100983997B1 (ko) 2001-01-09 2010-09-28 메르크 파텐트 게엠베하 수용체 타이로신 키나아제 저해제 및 혈관형성 저해제를 사용하는 병용 요법
EP1490113A4 (en) 2002-03-20 2007-05-02 Univ Florida ADENO-ASSOCIATED RECOMBINANT VIRAL VECTOR (RAAV) COMPOSITIONS AND CORRESPONDING METHODS FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION
CU23178A1 (es) 2002-04-15 2006-09-22 Ct Ingenieria Genetica Biotech INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA
DE60336555D1 (de) 2002-06-21 2011-05-12 Novo Nordisk Healthcare Ag Pegylierte glykoformen von faktor vii
WO2004085478A2 (en) 2003-03-26 2004-10-07 Apogenix Gmbh Improved fc fusion proteins
US20060198819A1 (en) 2003-08-08 2006-09-07 Novo Nordisk Healthcare A/G Use of galactose oxidase for selective chemical conjugation of protractor molecules to proteins of therapeutic interest
JP4944032B2 (ja) * 2004-09-13 2012-05-30 ジェンザイム・コーポレーション 多量体構築物
JP2008524241A (ja) 2004-12-17 2008-07-10 ジェネンテック・インコーポレーテッド 従来の治療の効果がなかった患者の自己免疫性疾患の血管新生阻害治療
WO2010019263A2 (en) * 2008-08-15 2010-02-18 Genzyme Corporation Soluble flt constructs for treating cancers

Also Published As

Publication number Publication date
HRP20180154T1 (hr) 2018-03-09
SI2601214T1 (en) 2018-03-30
CY1121111T1 (el) 2019-12-11
WO2012019128A1 (en) 2012-02-09
US10308917B2 (en) 2019-06-04
LT2601214T (lt) 2018-02-26
DK2601214T3 (en) 2018-02-05
US20160326501A1 (en) 2016-11-10
PL2601214T3 (pl) 2018-05-30
ES2652508T3 (es) 2018-02-02
EP2601214A1 (en) 2013-06-12
US20130324465A1 (en) 2013-12-05
EP2601214B1 (en) 2017-11-01
US9441029B2 (en) 2016-09-13
HUE035554T2 (en) 2018-05-02
EP3327032A1 (en) 2018-05-30

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