PT2347775T - Estruturas em andaime para transplante celular - Google Patents
Estruturas em andaime para transplante celularInfo
- Publication number
- PT2347775T PT2347775T PT101945657T PT10194565T PT2347775T PT 2347775 T PT2347775 T PT 2347775T PT 101945657 T PT101945657 T PT 101945657T PT 10194565 T PT10194565 T PT 10194565T PT 2347775 T PT2347775 T PT 2347775T
- Authority
- PT
- Portugal
- Prior art keywords
- composition
- scaffolds
- cell transplantation
- scaffold
- bioactive
- Prior art date
Links
- 238000002054 transplantation Methods 0.000 title 1
- 230000000975 bioactive effect Effects 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000007115 recruitment Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001156—Tyrosinase and tyrosinase related proteinases [TRP-1 or TRP-2]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A61K39/00117—Mucins, e.g. MUC-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A61K39/001171—Gangliosides, e.g. GM2, GD2 or GD3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
- A61K39/001182—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/001186—MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A61K39/001191—Melan-A/MART
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A61K39/001192—Glycoprotein 100 [Gp100]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
- A61K39/001195—Prostate specific membrane antigen [PSMA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/438—Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/30—Materials or treatment for tissue regeneration for muscle reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Developmental Biology & Embryology (AREA)
- Botany (AREA)
- Wood Science & Technology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74999805P | 2005-12-13 | 2005-12-13 | |
US81413406P | 2006-06-16 | 2006-06-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2347775T true PT2347775T (pt) | 2020-07-14 |
Family
ID=38163533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT101945657T PT2347775T (pt) | 2005-12-13 | 2006-12-13 | Estruturas em andaime para transplante celular |
Country Status (13)
Country | Link |
---|---|
US (8) | US8067237B2 (pt) |
EP (3) | EP2347774B1 (pt) |
JP (5) | JP5539649B2 (pt) |
AT (1) | ATE534415T1 (pt) |
AU (1) | AU2006326405B2 (pt) |
CA (1) | CA2632630C (pt) |
DK (1) | DK2347775T3 (pt) |
ES (1) | ES2804472T3 (pt) |
HU (1) | HUE051267T2 (pt) |
PL (1) | PL2347775T3 (pt) |
PT (1) | PT2347775T (pt) |
SI (1) | SI2347775T1 (pt) |
WO (1) | WO2007070660A2 (pt) |
Families Citing this family (132)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7767221B2 (en) * | 2004-03-05 | 2010-08-03 | The Trustees Of Columbia University In The City Of New York | Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone |
US8153435B1 (en) | 2005-03-30 | 2012-04-10 | Tracer Detection Technology Corp. | Methods and articles for identifying objects using encapsulated perfluorocarbon tracers |
EP2347774B1 (en) | 2005-12-13 | 2017-07-26 | The President and Fellows of Harvard College | Scaffolds for cell transplantation |
US8278094B2 (en) | 2005-12-14 | 2012-10-02 | The Invention Science Fund I, Llc | Bone semi-permeable device |
US7855062B2 (en) * | 2005-12-14 | 2010-12-21 | The Invention Science Fund I, Llc | Bone cell delivery device |
US8852916B2 (en) * | 2010-01-22 | 2014-10-07 | The Invention Science Fund I, Llc | Compositions and methods for therapeutic delivery with microorganisms |
US8682619B2 (en) * | 2005-12-14 | 2014-03-25 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
US8354258B2 (en) | 2005-12-14 | 2013-01-15 | The Invention Science Fund I, Llc | Diatom device |
US8734823B2 (en) * | 2005-12-14 | 2014-05-27 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
US9005944B2 (en) * | 2005-12-14 | 2015-04-14 | The Invention Science Fund I, Llc | Bone cell delivery device |
US8900865B2 (en) * | 2005-12-14 | 2014-12-02 | The Invention Science Fund I, Llc | Blood brain barrier device |
US20110172826A1 (en) * | 2005-12-14 | 2011-07-14 | Amodei Dario G | Device including altered microorganisms, and methods and systems of use |
US9061075B2 (en) | 2005-12-14 | 2015-06-23 | The Invention Science Fund I, Llc | Bone delivery device |
WO2007103209A2 (en) * | 2006-03-01 | 2007-09-13 | Fmc Biopolymer As | Gelled composite |
US9485917B2 (en) | 2006-12-15 | 2016-11-08 | Ecovative Design, LLC | Method for producing grown materials and products made thereby |
US8753391B2 (en) | 2007-02-12 | 2014-06-17 | The Trustees Of Columbia University In The City Of New York | Fully synthetic implantable multi-phased scaffold |
KR20100016187A (ko) * | 2007-04-06 | 2010-02-12 | 카리디안비씨티, 인크. | 개선된 생물반응기 표면 |
US9770535B2 (en) * | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
KR100932688B1 (ko) * | 2007-07-06 | 2009-12-21 | 한국과학기술연구원 | 인공혈관용 이중막 구조의 튜브형 다공성 스캐폴드 및 그의제조방법 |
US20090081276A1 (en) * | 2007-08-13 | 2009-03-26 | Eben Alsberg | Bioresorbable implant composition |
JP2009051773A (ja) * | 2007-08-27 | 2009-03-12 | Toyobo Co Ltd | 細胞接着能を有するhsp70ファミリータンパク質 |
US8266791B2 (en) | 2007-09-19 | 2012-09-18 | The Charles Stark Draper Laboratory, Inc. | Method of fabricating microfluidic structures for biomedical applications |
US8221744B2 (en) * | 2007-09-19 | 2012-07-17 | Abbott Cardiovascular Systems Inc. | Cytocompatible alginate gels |
JP5589274B2 (ja) * | 2007-10-25 | 2014-09-17 | 東レ株式会社 | 免疫誘導剤 |
US8198083B1 (en) | 2007-10-31 | 2012-06-12 | William Gunter Loudon | Organotypic slices of the central nervous system |
WO2009102465A2 (en) * | 2008-02-13 | 2009-08-20 | President And Fellows Of Harvard College | Continuous cell programming devices |
US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
US20110014153A1 (en) | 2008-03-27 | 2011-01-20 | Kathleen Derwin | Reinforced tissue graft |
US20130116799A1 (en) | 2008-03-27 | 2013-05-09 | The Cleveland Clinic Foundation | Reinforced tissue graft |
CN102089425A (zh) * | 2008-05-07 | 2011-06-08 | Ucl商业有限公司 | 仿生细胞支架 |
WO2009146456A1 (en) | 2008-05-30 | 2009-12-03 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
WO2010000741A1 (en) | 2008-06-30 | 2010-01-07 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of cd31 peptides in the treatment of thrombotic and autoimmune disorders |
EP2196196A1 (en) * | 2008-12-10 | 2010-06-16 | Medipol S.A. | Compound, medicament, vaccine composition and nanocapsules |
WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
US8551749B2 (en) * | 2009-04-23 | 2013-10-08 | The Invention Science Fund I, Llc | Device including bone cage and method for treatment of disease in a subject |
US20150335400A1 (en) * | 2009-06-17 | 2015-11-26 | The Trustees Of Columbia University In The City Of New York | Tooth scaffolds |
JP5750793B2 (ja) * | 2009-07-22 | 2015-07-22 | 国立大学法人信州大学 | Es細胞の継代方法及びes細胞増殖方法 |
US8728456B2 (en) | 2009-07-31 | 2014-05-20 | President And Fellows Of Harvard College | Programming of cells for tolerogenic therapies |
PL2470228T3 (pl) | 2009-08-28 | 2018-03-30 | Sernova Corporation | Sposoby i urządzenia do przeszczepiania komórek |
WO2011109712A2 (en) * | 2010-03-04 | 2011-09-09 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Bioengineered human corneal stromal tissue |
EP2542230A4 (en) | 2010-03-05 | 2013-08-28 | Harvard College | ENHANCEMENT OF SKELETAL MUSCLE STRAIN CELL GRAFT WITH DUAL DELIVERY OF VEGF AND IGF-1 |
ES2643087T3 (es) | 2010-03-29 | 2017-11-21 | Ferring B.V. | Composición farmacéutica de disolución rápida |
JO3112B1 (ar) | 2010-03-29 | 2017-09-20 | Ferring Bv | تركيبة دوائية سريعة التحلل |
WO2011127458A2 (en) * | 2010-04-09 | 2011-10-13 | University Of Southern California | Systems and methods of cell activated, controlled release delivery of growth factors for tissue repair and regeneration |
EP2558024B1 (en) * | 2010-04-12 | 2017-03-08 | The University Of Miami | Macroporous bioengineered scaffolds for cell transplantation |
US20110269231A1 (en) * | 2010-04-22 | 2011-11-03 | Wisconsin Alumni Research Foundation | Proteoglycan-binding peptides that modulate stem cell behavior |
TWI415638B (zh) * | 2010-04-29 | 2013-11-21 | Nat Health Research Institutes | Composite material for repairing cartilage tissue and preparation method thereof |
EP2585053A4 (en) | 2010-06-25 | 2014-02-26 | Harvard College | COMMON RELEASE OF STIMULATING AND HEMMING FACTORS FOR THE PRODUCTION OF TEMPORARY STABILIZED AND SPATULARLY LIMITED ZONES |
US20130280318A1 (en) * | 2010-07-12 | 2013-10-24 | The Trustees Of Columbia University In The City Of New York | Tissue Scaffolds for Controlled Release of Active Agents |
US9938501B2 (en) | 2010-07-28 | 2018-04-10 | Jointechlabs, Inc. | Encapsulated adipose-derived stem cells, methods for preparation and theraputic use |
EP2624873B1 (en) * | 2010-10-06 | 2019-12-04 | President and Fellows of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
EP2630234B1 (en) * | 2010-10-18 | 2017-12-13 | Sunshine Biotech Inc. | Human multipotent embryonic stem cell-like progenitor cells |
WO2012064697A2 (en) | 2010-11-08 | 2012-05-18 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
WO2012148684A1 (en) * | 2011-04-27 | 2012-11-01 | President And Fellows Of Harvard College | Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation |
US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
EP2701745B1 (en) | 2011-04-28 | 2018-07-11 | President and Fellows of Harvard College | Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration |
US9422373B2 (en) | 2011-06-02 | 2016-08-23 | Massachusetts Institute Of Technology | Modified alginates for cell encapsulation and cell therapy |
US9486512B2 (en) | 2011-06-03 | 2016-11-08 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
US8753309B2 (en) | 2011-06-24 | 2014-06-17 | The Invention Science Fund I, Llc | Device, system, and method including micro-patterned cell treatment array |
FR2979110B1 (fr) * | 2011-08-16 | 2013-09-27 | Etat Francais Ministere De La Defense Service De Sante Des Armees | Modelisation in vitro des niches medullaires a cellules souches hematopoietiques : un outil pour etudier la regulation de l'hematopoiese, evaluer le potentiel de nichage d'un greffon hematopoietique et tester la pharmaco-toxicologie de medicaments. |
JP5876787B2 (ja) | 2011-08-31 | 2016-03-02 | 富士フイルム株式会社 | 細胞移植用細胞構造体および細胞移植用細胞集合体 |
WO2013037708A1 (en) | 2011-09-16 | 2013-03-21 | Ferring B.V. | A fast dissolving pharmaceutical composition |
JP6018477B2 (ja) * | 2011-11-11 | 2016-11-02 | Hoya株式会社 | 人工骨−軟骨複合体及びその製造方法 |
AU2013207687B2 (en) * | 2012-01-13 | 2017-11-30 | Dana-Farber Cancer Institute, Inc. | Controlled delivery of TLR agonists in structural polymeric devices |
US9861663B2 (en) * | 2012-02-23 | 2018-01-09 | Technion Research & Development Foundation Ltd. | Ex-vivo vascularized implant composition comprising poly-l-lactic acid, polylactic-co-glycolic-acid and olfactory bulb cells |
HUE047973T2 (hu) | 2012-04-16 | 2020-05-28 | Harvard College | Mezoporózus szilíciumdioxid készítmények immunválaszok modulálására |
US9999590B2 (en) | 2012-07-12 | 2018-06-19 | Ferring B.V. | Diclofenac formulations |
WO2014063168A1 (en) | 2012-10-19 | 2014-04-24 | The Broad Institute, Inc. | Heterocycle-bisamide inhibitors of scavenger receptor bl |
WO2014081940A1 (en) * | 2012-11-21 | 2014-05-30 | Trustees Of Boston University | Tissue markers and uses thereof |
US20160008399A1 (en) | 2013-01-14 | 2016-01-14 | Fred Hutchinson Cancer Research Center | Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse |
WO2014165652A1 (en) | 2013-04-03 | 2014-10-09 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Pem layer-by-layer systems for coating substrates to improve bioactivity and biomolecule delivery |
WO2014169250A1 (en) * | 2013-04-11 | 2014-10-16 | President And Fellows Of Harvard College | Prefabricated alginate-drug bandages |
WO2014169249A1 (en) | 2013-04-12 | 2014-10-16 | The Trustees Of Columbia University In The City Of New York | Methods for host cell homing and dental pulp regeneration |
US10098982B2 (en) | 2013-11-20 | 2018-10-16 | Drexel University | Compositions and methods for macrophage conversion |
JP6787789B2 (ja) | 2014-04-04 | 2020-11-18 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 詰め替え可能な薬物送達デバイスおよびその使用方法 |
US10682400B2 (en) | 2014-04-30 | 2020-06-16 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
WO2015192017A1 (en) * | 2014-06-12 | 2015-12-17 | President And Fellows Of Harvard College | Interpenetrating network hydrogels with independently tunable stiffness |
JP6104312B2 (ja) * | 2014-06-19 | 2017-03-29 | 日東電工株式会社 | 組織再生促進剤 |
CN106714854B (zh) * | 2014-07-17 | 2020-09-04 | 加利福尼亚大学董事会 | 用于生物医学应用的可控的自退火微凝胶颗粒 |
CN106795225B (zh) | 2014-08-01 | 2021-03-19 | 麻省理工学院 | 用于抗纤维化材料的修饰的藻酸盐以及应用 |
MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
CN114920840A (zh) | 2014-10-14 | 2022-08-19 | 诺华股份有限公司 | 针对pd-l1的抗体分子及其用途 |
US20160158414A1 (en) * | 2014-12-08 | 2016-06-09 | Cormatrix Cardiovascular, Inc. | Anisotropic Constructs and Methods for Forming and Using Same for Treating Damaged Biological Tissue |
WO2016123573A1 (en) | 2015-01-30 | 2016-08-04 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
AU2016243612A1 (en) * | 2015-03-31 | 2017-10-12 | The University Of North Carolina At Chapel Hill | Delivery vehicles for stem cells and uses thereof |
TWI741980B (zh) | 2015-04-07 | 2021-10-11 | 大陸商四川藍光英諾生物科技股份有限公司 | 一種生物磚及其用途 |
EP3903843A1 (en) | 2015-04-07 | 2021-11-03 | Revotek Co., Ltd | Compositions for cell-based three dimensional printing |
CN107708756A (zh) * | 2015-04-10 | 2018-02-16 | 哈佛学院院长等 | 免疫细胞捕获装置及其制备和使用方法 |
DE102015122375A1 (de) | 2015-05-29 | 2016-12-01 | Technische Universität Ilmenau | Nachbildung einer Stammzellnische eines Organismus sowie Verfahren zu deren Erzeugung |
EP3878465A1 (en) | 2015-07-29 | 2021-09-15 | Novartis AG | Combination therapies comprising antibody molecules to tim-3 |
EP3964528A1 (en) | 2015-07-29 | 2022-03-09 | Novartis AG | Combination therapies comprising antibody molecules to lag-3 |
JP6741408B2 (ja) * | 2015-09-11 | 2020-08-19 | 国立大学法人横浜国立大学 | 細胞包埋ビーズ及びその製造方法 |
JP6675859B2 (ja) * | 2015-10-30 | 2020-04-08 | 国立大学法人横浜国立大学 | 血管網被包細胞包埋ビーズ及びその製造方法、並びに前記血管網被包細胞包埋ビーズを用いた集積体及びその製造方法 |
EP3368085B1 (en) * | 2015-11-01 | 2024-01-03 | Massachusetts Institute Of Technology | Modified alginates for anti-fibrotic materials and applications |
AU2016369537B2 (en) | 2015-12-17 | 2024-03-14 | Novartis Ag | Antibody molecules to PD-1 and uses thereof |
US20190008971A1 (en) * | 2016-01-07 | 2019-01-10 | The Regents Of The University Of Michigan | Implantable Scaffolds for Capturing Metastatic Breast Cancer Cells In Vivo |
EP3190176A1 (en) | 2016-01-11 | 2017-07-12 | IMBA-Institut für Molekulare Biotechnologie GmbH | Method for tissue culture development on scaffold and differentiated tissue culture |
CN115487351A (zh) * | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
WO2017136950A1 (en) * | 2016-02-12 | 2017-08-17 | University Of Ottawa | Decellularised cell wall structures from plants and fungus and use thereof as scaffold materials |
US10813988B2 (en) | 2016-02-16 | 2020-10-27 | President And Fellows Of Harvard College | Pathogen vaccines and methods of producing and using the same |
CA3017259A1 (en) | 2016-03-07 | 2017-09-14 | The Regents Of The University Of California | Bioartificial ultrafiltration device and methods related thereto |
AU2017283463A1 (en) | 2016-06-13 | 2019-01-17 | Massachusetts Institute Of Technology | Biocompatible zwitterionic polymer coatings and hydrogels for reducing foreign body response and fibrosis |
CA3029813A1 (en) | 2016-06-13 | 2017-12-21 | Torque Therapeutics, Inc. | Methods and compositions for promoting immune cell function |
JP7044330B2 (ja) * | 2016-06-17 | 2022-03-30 | 国立大学法人横浜国立大学 | 毛髪再生用細胞包埋ビーズ及びその製造方法、並びに毛髪再生用キット |
EP3484448A4 (en) | 2016-07-13 | 2020-04-01 | President and Fellows of Harvard College | MIMETIC SCAFFOLDS OF CELLS HAVING ANTIGEN AND METHODS OF PREPARING AND USING THEM |
FR3055805B1 (fr) * | 2016-09-09 | 2020-05-15 | Assistance Publique - Hopitaux De Paris (Ap-Hp) | Biomateriau a usage therapeutique |
US11150251B2 (en) | 2016-10-07 | 2021-10-19 | Clemson University Research Foundation | Bi-functional arginine-glycine-aspartic acid (RGD) peptides and methods to promote angiogenesis |
AU2017363878A1 (en) * | 2016-11-22 | 2019-06-13 | Nutech Ventures | Personalized cellular biomanufacturing with a closed, miniature cell culture system |
JP2020515544A (ja) * | 2017-03-25 | 2020-05-28 | ユニバーシティ オブ マイアミ | 治療細胞を含む生物学的足場 |
CA3063847A1 (en) | 2017-05-16 | 2018-11-22 | Embody Inc. | Biopolymer compositions, scaffolds and devices |
AU2018271094B2 (en) * | 2017-05-17 | 2024-03-21 | Advanced Aesthetic Technologies, Inc. | Agaroid structures and related methods of use and manufacture |
EP3409303A1 (en) * | 2017-06-02 | 2018-12-05 | Geistlich Pharma AG | Use of a resorbable crosslinked form stable composition for preparing a membrane |
WO2018227205A1 (en) * | 2017-06-09 | 2018-12-13 | President And Fellows Of Harvard College | Compositions for inducing an immune response |
KR20200028391A (ko) * | 2017-06-12 | 2020-03-16 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 세포 생착용 패치 이식편 조성물 |
WO2019018727A1 (en) | 2017-07-21 | 2019-01-24 | Washington University | METHODS AND COMPOSITIONS FOR T-CELL ACTIVATION |
EP3678701A4 (en) | 2017-09-05 | 2021-12-01 | Torque Therapeutics, Inc. | THERAPEUTIC PROTEIN COMPOSITIONS AND METHOD FOR MANUFACTURING AND USING THEREOF |
WO2019079384A1 (en) | 2017-10-17 | 2019-04-25 | The Methodist Hospital System | ADMINISTRATION DEVICES |
JP2021500160A (ja) | 2017-10-24 | 2021-01-07 | エムボディ インコーポレイテッド | 生体高分子足場移植片およびその生成のための方法 |
WO2019090309A1 (en) | 2017-11-06 | 2019-05-09 | Massachusetts Institute Of Technology | Anti-inflammatory coatings to improve biocompatibility of neurological implants |
GB2573327B (en) * | 2018-05-03 | 2021-05-12 | Mosa Meat Bv | Apparatus and process for production of tissue from cells |
US20210207083A1 (en) * | 2018-06-04 | 2021-07-08 | Ramot At Tel-Aviv University Ltd. | Support medium for 3d printing of biomaterials |
WO2020023462A1 (en) * | 2018-07-23 | 2020-01-30 | Georgia Tech Research Corporation | Synthetic hydrogel carriers for muscle repair |
JP7269594B2 (ja) * | 2018-09-27 | 2023-05-09 | 株式会社村田製作所 | 細胞分離フィルター及び細胞分離方法 |
WO2020082090A1 (en) * | 2018-10-19 | 2020-04-23 | The Regents Of The University Of Michigan | Method for monitoring autoimmune disease |
SG11202105283PA (en) * | 2018-11-20 | 2021-06-29 | Ecovative Design Llc | Methods of generating mycelial scaffolds and applications thereof |
WO2020131582A1 (en) * | 2018-12-17 | 2020-06-25 | President And Fellows Of Harvard College | Bioengineered scaffolds for modulation of immune system and the uses thereof |
EP3917756A4 (en) | 2019-02-01 | 2023-05-10 | Embody Inc. | MICROFLUIDIC EXTRUSION |
CN116904079A (zh) * | 2019-05-15 | 2023-10-20 | 积水化学工业株式会社 | 由细胞培养用支架材料形成的树脂膜、细胞培养用载体和细胞培养用容器 |
CN112089883B (zh) * | 2020-09-14 | 2022-01-04 | 海南希睿达生物技术有限公司 | 一种医用冷敷敷料及其制备方法 |
KR102348467B1 (ko) * | 2021-07-14 | 2022-01-07 | 주식회사 휴메딕스 | Dna 분획물을 포함하는 필러 제조방법 및 이로부터 제조된 필러 |
WO2023147291A2 (en) * | 2022-01-25 | 2023-08-03 | The Board Of Trustees Of The Leland Stanford Junior University | Gene editing and delivery of myeloid cells to promote wound healing |
WO2023158629A1 (en) * | 2022-02-15 | 2023-08-24 | The Regents Of The University Of Michigan | Platform for monitoring transplant rejection |
Family Cites Families (247)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
GB9206504D0 (en) * | 1992-03-25 | 1992-05-06 | Jevco Ltd | Heteromorphic sponges as wound implants |
WO1995016464A1 (en) | 1993-12-14 | 1995-06-22 | Johns Hopkins University School Of Medicine | Controlled release of pharmaceutically active substances for immunotherapy |
US5538733A (en) | 1994-07-07 | 1996-07-23 | Willmar Poultry Company, Inc. | Method of priming an immune response in a one-day old animal |
US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
US6194388B1 (en) | 1994-07-15 | 2001-02-27 | The University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
US5625048A (en) | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
US6329499B1 (en) | 1994-11-18 | 2001-12-11 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein |
US6251396B1 (en) | 1994-11-18 | 2001-06-26 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
BR9708387A (pt) | 1996-03-28 | 2000-01-04 | Genitrix Llc | Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada. |
IL118376A0 (en) | 1996-05-22 | 1996-09-12 | Univ Ben Gurion | Polysaccharide sponges for cell culture and transplantation |
EP0915967A1 (en) | 1996-05-28 | 1999-05-19 | The Board Of Regents Of The University Of Michigan | Engineering oral tissues |
US6124128A (en) | 1996-08-16 | 2000-09-26 | The Regents Of The University Of California | Long wavelength engineered fluorescent proteins |
ATE413415T1 (de) | 1996-09-19 | 2008-11-15 | Univ Michigan | Polymere enthaltend polysaccharide wie alginate oder modifizierte alginate |
US5863551A (en) | 1996-10-16 | 1999-01-26 | Organogel Canada Ltee | Implantable polymer hydrogel for therapeutic uses |
GB2318577B (en) | 1996-10-28 | 2000-02-02 | Johnson & Johnson Medical | Solvent dried polysaccharide sponges |
GB2323282B (en) | 1997-03-17 | 2001-03-07 | Bristol Myers Squibb Co | Improvements relating to hygiene and medical products |
JP4085341B2 (ja) | 1997-03-31 | 2008-05-14 | ザ、リージエンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン | 開いたポアの生分解性マトリックス |
DE69840171D1 (de) | 1997-05-30 | 2008-12-11 | Osteobiologics Inc | Faserverstärkte,poröse,biologisch abbaubare implantatvorrichtung |
KR100497849B1 (ko) | 1997-08-21 | 2005-06-29 | 다카라 바이오 가부시키가이샤 | 제암제 |
ES2221363T3 (es) | 1998-02-23 | 2004-12-16 | Massachusetts Institute Of Technology | Polimeros biodegradables con memoria de forma. |
WO1999044583A2 (en) | 1998-03-02 | 1999-09-10 | Applied Vaccine Technologies Corp. | Methods and devices for modulating the immune response |
ATE356630T1 (de) | 1998-04-03 | 2007-04-15 | Univ Iowa Res Found | Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine |
WO1999052356A1 (en) | 1998-04-09 | 1999-10-21 | Charlotte-Mecklenberg Hospital Authority | Creation of three-dimensional tissues |
US7427602B1 (en) | 1998-05-13 | 2008-09-23 | The Regents Of The University Of Michigan | Sustained DNA delivery from structural matrices |
US7244714B1 (en) | 1998-06-12 | 2007-07-17 | Aradigm Corporation | Methods of delivering aerosolized polynucleotides to the respiratory tract |
FR2780730B1 (fr) | 1998-07-01 | 2000-10-13 | Corneal Ind | Compositions biphasiques injectables, notamment utiles en chirurgies reparatrice et esthetique |
EP2311485A1 (en) | 1998-07-30 | 2011-04-20 | The Government of the United States of America, as represented by the Secretary of Health and Human Services | Thymosin beta 4 promotes wound repair |
EP1374908A3 (en) | 1998-10-09 | 2004-03-24 | The Regents Of The University Of Michigan | Polymer-drug conjugates comprising hydrazide linkers |
DE69935606T9 (de) | 1998-10-16 | 2021-03-11 | Glaxosmithkline Biologicals S.A. | Adjuvanzsysteme und impfstoffe |
US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
US6974698B1 (en) | 1999-01-15 | 2005-12-13 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for delivering biologically active molecules into cells |
AU2875700A (en) | 1999-02-26 | 2000-09-14 | Chiron Corporation | Microemulsions with adsorbed macromoelecules and microparticles |
WO2000056375A2 (en) | 1999-03-19 | 2000-09-28 | The Regents Of The University Of Michigan | Mineralization and cellular patterning on biomaterial surfaces |
US6767928B1 (en) | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
ES2295021T3 (es) | 1999-03-25 | 2008-04-16 | Metabolix, Inc. | Utilizacion y aplicaciones medicas de polimeros de poli(hidroxialcanoatos). |
EP1169378A4 (en) | 1999-04-09 | 2004-06-02 | Univ Michigan | PREPARATION OF PRODUCTS BASED ON HYDROGEL |
US6306424B1 (en) | 1999-06-30 | 2001-10-23 | Ethicon, Inc. | Foam composite for the repair or regeneration of tissue |
AU782297B2 (en) * | 1999-06-30 | 2005-07-14 | Ethicon Inc. | Porous tissue scaffoldings for the repair or regeneration of tissue |
US8084258B2 (en) | 1999-07-12 | 2011-12-27 | University Of Basel | Manipulation of tissue of organ type using the notch pathway |
AU6526100A (en) * | 1999-08-06 | 2001-03-05 | Board Of Regents, The University Of Texas System | Drug releasing biodegradable fiber implant |
US7015205B1 (en) | 1999-10-18 | 2006-03-21 | St. Vincent's Hospital And Medical Center Of New York | Melanoma vaccine and methods of making and using same |
WO2001035932A2 (en) | 1999-11-18 | 2001-05-25 | The Regents Of The University Of Michigan | Sustained drug delivery from structural matrices |
US6682754B2 (en) | 1999-11-24 | 2004-01-27 | Willmar Poultry Company, Inc. | Ovo delivery of an immunogen containing implant |
US6790840B1 (en) | 1999-11-26 | 2004-09-14 | The Regents Of The University Of Michigan | Reversibly cross-linked hydrogels |
AU2001284695A1 (en) | 2000-07-31 | 2002-02-13 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US7635592B2 (en) | 2000-08-21 | 2009-12-22 | Rice University | Tissue engineering scaffolds promoting matrix protein production |
AU2001288437C1 (en) | 2000-09-09 | 2009-05-21 | The Research Foundation Of State University Of New York | Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof |
US6748954B2 (en) | 2000-10-27 | 2004-06-15 | The Regents Of The University Of Michigan | Drug release from polymer matrices through mechanical stimulation |
AU2002212739A1 (en) * | 2000-11-14 | 2002-05-27 | Osteogenesis Co., Ltd. | Compositions for forming bone or periodontium and injections for forming bone orperiodontium |
US20040043034A1 (en) | 2000-11-27 | 2004-03-04 | Jensenius Jens Christian | Collectins as adjuvants |
US8554940B2 (en) | 2001-01-19 | 2013-10-08 | Single Touch Interactive, Inc. | System and method for routing media |
EP1392351A2 (en) | 2001-01-24 | 2004-03-03 | Schering Corporation | Chemokines as adjuvants of immune response |
US7029697B2 (en) | 2001-02-14 | 2006-04-18 | Northwestern University | Controlled surface-associated delivery of genes and oligonucleotides |
WO2002068605A2 (en) | 2001-02-26 | 2002-09-06 | The Regents Of The University Of California | Non-oligomerizing tandem fluorescent proteins |
US20020131953A1 (en) | 2001-03-14 | 2002-09-19 | Ut Southwestern Medical Center | In situ langerhans cell vaccine |
JP2002263981A (ja) | 2001-03-14 | 2002-09-17 | Murata Mach Ltd | 板材吸着持ち上げ装置の吸着制御装置 |
US6656488B2 (en) | 2001-04-11 | 2003-12-02 | Ethicon Endo-Surgery, Inc. | Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering |
US20030082806A1 (en) * | 2001-04-27 | 2003-05-01 | Xcyte Therapies, Inc. | Maturation of antigen-presenting cells using activated T cells |
CN1289063C (zh) | 2001-05-11 | 2006-12-13 | 奥索-麦克尼尔药品公司 | 用于动物的免疫调节装置 |
US20030118630A1 (en) | 2001-12-07 | 2003-06-26 | Anthony Cerami | Immune modulation device for use in animals |
WO2002101385A1 (en) | 2001-06-13 | 2002-12-19 | Massachusetts Institute Of Technology | In vivo bioreactors |
US7297343B2 (en) * | 2001-07-31 | 2007-11-20 | Biosurface Engineering Technologies, Inc. | Bioactive medical films |
AU2002361468A1 (en) | 2001-08-14 | 2003-03-18 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human S | Method for rapid generation of mature dendritic cells |
CA2412012C (en) * | 2001-11-20 | 2011-08-02 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage |
AU2002361902A1 (en) | 2001-12-31 | 2003-07-24 | Ares Medical, Inc. | Hemostatic compositions and methods for controlling bleeding |
US7575759B2 (en) | 2002-01-02 | 2009-08-18 | The Regents Of The University Of Michigan | Tissue engineering scaffolds |
WO2003070291A1 (fr) | 2002-02-19 | 2003-08-28 | National Institute Of Advanced Industrial Science And Technology | Implant contenant des cellules dans lesquelles on a transfere un gene du facteur de croissance |
US20080233181A1 (en) | 2002-04-12 | 2008-09-25 | Nagy Jon O | Nanoparticle adjuvants for sub-unit vaccines |
US6811777B2 (en) * | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
WO2003089506A1 (en) | 2002-04-22 | 2003-10-30 | Purdue Research Foundation | Hydrogels having enhanced elasticity and mechanical strength properties |
KR101092043B1 (ko) | 2002-04-22 | 2011-12-12 | 바이오니취 라이프 사이언시즈 인코포레이티드 | 올리고뉴클레오티드 조성물 및 면역 반응 조절시 이의 용도 |
AU2003249606A1 (en) | 2002-05-13 | 2003-12-02 | Massachusetts Institute Of Technology | Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof |
AUPS312602A0 (en) | 2002-06-21 | 2002-07-18 | James Cook University | Organ arrest, protection, preservation and recovery |
US7332160B2 (en) | 2002-07-12 | 2008-02-19 | Boston Scientific Scimed, Inc. | Medical device and method for tissue removal and repair |
EP2267021B1 (en) | 2002-09-12 | 2015-02-18 | Oncotherapy Science, Inc. | KDR peptides and vaccines comprising the same |
US20040136968A1 (en) * | 2002-09-27 | 2004-07-15 | Verigen Ag | Autologous cells on a support matrix for tissue repair |
US20040063206A1 (en) * | 2002-09-30 | 2004-04-01 | Rowley Jon A. | Programmable scaffold and method for making and using the same |
WO2004030706A2 (en) * | 2002-10-01 | 2004-04-15 | Law Peter K | Bioactive implants |
JP2004159849A (ja) | 2002-11-12 | 2004-06-10 | National Institute Of Advanced Industrial & Technology | 細胞接着性生体吸収材料、人工血管およびそれらの製造方法 |
AU2003288675B2 (en) | 2002-12-23 | 2010-07-22 | Medimmune Limited | Antibodies against PD-1 and uses therefor |
US8940292B2 (en) | 2003-01-28 | 2015-01-27 | Wake Forest University Health Sciences | Enhancement of angiogenesis to grafts using cells engineered to produce growth factors |
SE0301109D0 (sv) | 2003-04-14 | 2003-04-14 | Mallen Huang | Nucleotide vaccine composition |
KR101180896B1 (ko) | 2003-05-05 | 2012-09-07 | 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 | 주사용 가교결합된 폴리머 제제 및 그의 용도 |
EP1475434A1 (en) | 2003-05-09 | 2004-11-10 | Oncoscience AG | Method for storing tumor cells |
JP2007528848A (ja) | 2003-07-09 | 2007-10-18 | ヴァックスデザイン・コーポレーション | ワクチン接種ノードを用いるプログラムされた免疫応答 |
US20060264380A1 (en) | 2003-07-21 | 2006-11-23 | Mats Hellstrom | Compounds and Methods for Promoting Angiogenesis |
US8247231B2 (en) | 2003-07-31 | 2012-08-21 | Wilson Constance N | Methods and compositions for producing antigenic responses |
GB0317999D0 (en) | 2003-07-31 | 2003-09-03 | Univ Liege | Improvements in or relating to drug delivery systems |
US20080206308A1 (en) | 2003-08-29 | 2008-08-28 | Esmaiel Jabbari | Hydrogel Porogents for Fabricating Biodegradable Scaffolds |
JP5097400B2 (ja) * | 2003-09-03 | 2012-12-12 | デンドリセラピューティクス、インク. | 複合ワクチン |
GB0321615D0 (en) | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Improvements in vaccination |
JP5021309B2 (ja) | 2003-10-16 | 2012-09-05 | ステファン ジョン ラルフ | 免疫調節性組成物およびその使用方法 |
JP2007510470A (ja) | 2003-11-07 | 2007-04-26 | カーネギー・メロン・ユニバーシテイ | 最小侵襲性介入用ロボット |
CA2448995A1 (en) | 2003-11-12 | 2005-05-12 | James Keenan | Device and method for attracting diseased cells and foreign substances |
JP2005160669A (ja) * | 2003-12-02 | 2005-06-23 | Olympus Corp | 生体組織補填体の製造方法 |
JP2005170816A (ja) * | 2003-12-09 | 2005-06-30 | Naoki Ishiguro | 軟骨修復用材料、およびその製造方法 |
JP2005168760A (ja) | 2003-12-10 | 2005-06-30 | Gunze Ltd | 再生医療用支持体、血管再生用支持体、神経再生用支持体及び治療方法 |
EP1697511A4 (en) | 2003-12-11 | 2007-11-21 | Vaxdesign Corp | IMMUNOTHERAPY COMPOSITIONS, METHODS FOR PREPARING AND USING THE SAME |
US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
US7192693B2 (en) | 2004-02-24 | 2007-03-20 | University Of Washington | Methods for photopatterning hydrogels |
AU2005222626B2 (en) | 2004-03-15 | 2010-05-20 | Karagen Pharmaceuticals, Inc. | A method for inhibiting cancer cell proliferation or increasing cancer cell apoptosis |
WO2005104755A2 (en) | 2004-04-28 | 2005-11-10 | Vaxdesign Corporation | Artificial immune system: methods for making and use |
CA2567789A1 (en) | 2004-06-08 | 2006-08-03 | Coley Pharmaceutical Gmbh | Abasic oligonucleotide as carrier platform for antigen and immunostimulatory agonist and antagonist |
WO2007001332A2 (en) | 2004-08-04 | 2007-01-04 | University Of Massachusetts | Anti-pathogen immunoadhesins |
EP1784493A2 (en) | 2004-09-01 | 2007-05-16 | The Government of the United States of America as Represented by The Department of Health and Human Services | Adenoviral vectors able to transduce apcs, potential use in immune response generation |
US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
MX2007004261A (es) | 2004-10-12 | 2007-06-18 | Fmc Biopolymer As | Sistemas de alginato auto-gelificantes y usos de los mismos. |
WO2007042554A2 (en) | 2005-10-12 | 2007-04-19 | Cancer Research Technology Ltd. | Methods and compositions for treating immune disorders |
US7999161B2 (en) | 2005-01-22 | 2011-08-16 | Alexander Oraevsky | Laser-activated nanothermolysis of cells |
US7569850B2 (en) | 2005-01-24 | 2009-08-04 | Lawrence Livermore National Security, Llc | Lipid bilayers on nano-templates |
JP5199866B2 (ja) | 2005-03-23 | 2013-05-15 | メイヨ フオンデーシヨン フオー メデイカル エジユケーシヨン アンド リサーチ | 細胞及び薬物送達用の光架橋性オリゴ(ポリ(エチレングリコール)フマレート)ヒドロゲル |
CA2603116A1 (en) | 2005-03-29 | 2006-10-05 | The Regents Of The University Of California | Controlling stem cell destiny with tunable network |
EP1712238A1 (en) | 2005-04-11 | 2006-10-18 | Institut Gustave Roussy | Anthracyclin induced immunogenic dead or dying cells composition |
US20070003595A1 (en) | 2005-04-19 | 2007-01-04 | Shaopeng Wang | Three dimensional micro-environments and methods of making and using same |
US8828433B2 (en) | 2005-04-19 | 2014-09-09 | Advanced Cardiovascular Systems, Inc. | Hydrogel bioscaffoldings and biomedical device coatings |
CA2605749C (en) | 2005-04-26 | 2015-06-30 | Eisai Co., Ltd. | Compositions and methods for cancer immunotherapy |
WO2006119619A1 (en) | 2005-05-06 | 2006-11-16 | Replicor Inc. | Oligonucleotides inhibiting cell proliferation |
ITPI20050071A1 (it) | 2005-06-20 | 2006-12-21 | Giuseppe Calvosa | Composizione biocompatibile per la sostituzione/rigenerazione di tessuti |
US7645742B2 (en) | 2005-06-22 | 2010-01-12 | Advocare International, L.P. | Composition for enhancing cellular energy |
CN1302050C (zh) | 2005-07-07 | 2007-02-28 | 复旦大学 | 一种互穿网络聚合物超多孔水凝胶及其制备方法和应用 |
US20090017096A1 (en) | 2005-08-15 | 2009-01-15 | Anthony Lowman | Porous non-biodegradable hydrogel admixed with a chemoattractant for tissue replacement |
BRPI0503817A (pt) | 2005-09-12 | 2007-05-15 | Cristalia Prod Quimicos Farm | complexo imunogênico formado por antìgenos vacinais encapsulados por sìlica mesoporosa nanoestruturada |
CN107723274B (zh) | 2005-09-23 | 2021-05-07 | 塞勒里克斯有限公司 | 具有免疫调节活性的细胞群及其分离方法和用途 |
WO2007041190A2 (en) | 2005-09-30 | 2007-04-12 | The University Of Iowa Research Foundation | Polymer-based delivery system for immunotherapy of cancer |
US8029575B2 (en) | 2005-10-25 | 2011-10-04 | Globus Medical, Inc. | Porous and nonporous materials for tissue grafting and repair |
US20070116680A1 (en) | 2005-11-18 | 2007-05-24 | Rensselaer Polytechnic Institute | Stem cells within gel microenvironments |
WO2007063075A1 (en) | 2005-11-29 | 2007-06-07 | Actogenix Nv | Induction of mucosal tolerance to antigens |
KR100687281B1 (ko) | 2005-11-30 | 2007-02-27 | 한국과학기술연구원 | 생리 활성 물질이 결합된 조직 재생용 주입형 온도 감응성플루로닉 유도체 하이드로겔 및 이의 제조 방법 |
ES2419106T3 (es) | 2005-12-01 | 2013-08-19 | Pronai Therapeutics, Inc. | Formulación de liposomas anfóteros |
EP2347774B1 (en) | 2005-12-13 | 2017-07-26 | The President and Fellows of Harvard College | Scaffolds for cell transplantation |
AU2015264807A1 (en) | 2005-12-13 | 2015-12-17 | President And Fellows Of Harvard College | Scaffolds for Cell Transplantation |
US20090148487A1 (en) | 2005-12-14 | 2009-06-11 | Scil Technology Gmbh | Moldable biomaterial for bone regeneration |
EP1806395A1 (en) | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation of dendritic cells |
US7615556B2 (en) | 2006-01-27 | 2009-11-10 | Bristol-Myers Squibb Company | Piperazinyl derivatives as modulators of chemokine receptor activity |
US20070178159A1 (en) | 2006-01-30 | 2007-08-02 | Alza Corporation | In-Situ Forming Porous Scaffold |
CA2676601A1 (en) | 2006-01-31 | 2007-08-09 | Medivas, Llc | Vaccine delivery compositions and methods of use |
US20100015709A1 (en) | 2006-02-10 | 2010-01-21 | Trustees Of The University Of Pennsylvania | Regulating Stem Cell Differentiation By Controlling 2D and 3D Matrix Elasticity |
US20090041825A1 (en) | 2006-02-10 | 2009-02-12 | Kotov Nicholas A | Cell culture well-plates having inverted colloidal crystal scaffolds |
US20070190646A1 (en) | 2006-02-10 | 2007-08-16 | The Trustees Of The University Of Pennsylvania | Regulating stem cell differentiation by controlling matrix elasticity |
EP1988938A4 (en) | 2006-02-27 | 2011-09-28 | Agency Science Tech & Res | HARDENABLE BONE CEMENT |
US9456860B2 (en) | 2006-03-14 | 2016-10-04 | Kci Licensing, Inc. | Bioresorbable foaming tissue dressing |
GB0605521D0 (en) | 2006-03-18 | 2006-04-26 | Isis Innovation | Adjuvant |
WO2008127256A1 (en) | 2006-06-01 | 2008-10-23 | Massachusetts Institute Of Technology | Control of cells and cell multipotentiality in three dimensional matrices |
US20080138416A1 (en) | 2006-06-13 | 2008-06-12 | Fmc Biopolymer As | Method and systems for using biopolymer-based beads and hydrogels |
US20070298067A1 (en) | 2006-06-22 | 2007-12-27 | Boston Scientific Scimed, Inc. | Control release drug coating for medical devices |
EP2041175A4 (en) | 2006-06-23 | 2011-03-16 | Augmenta Biolog Llc | TARGETED IMMUNOJUGATE |
US8535719B2 (en) | 2006-07-07 | 2013-09-17 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biohybrid elastomeric scaffolds and methods of use thereof |
JP4989934B2 (ja) | 2006-07-14 | 2012-08-01 | パナソニック株式会社 | スピーカシステム |
US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
KR100802139B1 (ko) | 2006-08-08 | 2008-02-11 | 한국생명공학연구원 | 자성 나노입자를 함유하는 골드 나노케이지 |
KR100818708B1 (ko) | 2006-08-18 | 2008-04-01 | 주식회사 하이닉스반도체 | 표면 세정을 포함하는 반도체소자 제조방법 |
ITMI20061726A1 (it) | 2006-09-11 | 2008-03-12 | Fidia Farmaceutici | Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry |
CA2663722C (en) | 2006-09-21 | 2014-12-09 | Purdue Research Foundation | Collagen preparation and method of isolation |
CA2702340C (en) | 2006-10-12 | 2014-12-16 | The University Of Queensland | Compositions and methods for modulating immune responses |
JP5249236B2 (ja) | 2006-11-09 | 2013-07-31 | ケーシーアイ ライセンシング インコーポレイテッド | ミクロスフェアを具える多孔質の生体再吸収性結合ドレッシング及びその製造方法 |
WO2008086486A1 (en) | 2007-01-10 | 2008-07-17 | The Regents Of The University Of Michigan | Porous objects having immobilized encapsulated biomolecules |
DK2131856T3 (da) | 2007-03-07 | 2014-12-15 | Uti Limited Partnership | Sammensætninger og fremgangsmåder til forebyggelsen og behandlingen af autoimmune tilstande |
EP2181121A4 (en) | 2007-03-21 | 2012-07-11 | Id Biomedical Corp Quebec | CHIMÄRE ANTIGENE |
WO2008118392A2 (en) | 2007-03-22 | 2008-10-02 | The Regents Of The University Of California | Synthetic cell platforms and methods of use thereof |
EP1975230A1 (en) | 2007-03-30 | 2008-10-01 | Capsulution Nanoscience AG | Method for forming glucose sensing micro-particles, use of micro-particles, and kit |
US8188058B2 (en) | 2007-04-19 | 2012-05-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | Use of toll-like receptor-9 agonists, toll-like receptor-4 antagonists, and/or nuclear oligomerization domain-2 agonists for the treatment or prevention of toll-like receptor-4-associated disorders |
CN101687928A (zh) | 2007-06-05 | 2010-03-31 | 诺瓦提斯公司 | 成熟树突细胞中耐受性表型的诱导 |
US20090136470A1 (en) | 2007-06-13 | 2009-05-28 | Hilde Cheroutre | Regulatory t cells and methods of making and using same |
US9770535B2 (en) | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
EP2173859B1 (en) | 2007-06-29 | 2016-05-11 | Makoto Funaki | Soft gel systems in modulating stem cell development |
TR201000668T1 (tr) | 2007-07-31 | 2010-06-21 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Neoplasti̇k veya enfeksi̇yoz bozukluklara yöneli̇k i̇mmunoprofi̇laksi̇ veya i̇mmünoterapi̇ i̇çi̇n poli̇pepti̇d-nüklei̇k asi̇t konjugati |
GB0716264D0 (en) | 2007-08-21 | 2007-09-26 | Isis Innovation | Bilayers |
US20090192079A1 (en) | 2007-10-09 | 2009-07-30 | Genzyme Corporation | Prolonged delivery of heparin-binding growth factors from heparin-derivatized collagen |
KR100900837B1 (ko) | 2007-12-07 | 2009-06-04 | (주)두비엘 | 리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물 |
EP2072617A1 (en) | 2007-12-12 | 2009-06-24 | Trimed Biotech GmbH | Method for producing dendritic cells |
DE102008008522A1 (de) | 2008-02-11 | 2009-08-13 | Magforce Nanotechnologies Ag | Implantierbare Nanopartikel-enthaltende Produkte |
US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
WO2009102465A2 (en) | 2008-02-13 | 2009-08-20 | President And Fellows Of Harvard College | Continuous cell programming devices |
WO2011063336A2 (en) | 2009-11-20 | 2011-05-26 | President And Fellows Of Harvard College | Secondary site of antigen stimulation for therapeutic vaccination |
US20090238853A1 (en) | 2008-03-21 | 2009-09-24 | 3D Biotek, Llc | Hybrid Biomedical Device Fabricated From Biomaterials and Coated With a Natural Extra Cellular Matrix (ECM) Coating |
WO2009146456A1 (en) | 2008-05-30 | 2009-12-03 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
US20110182957A1 (en) | 2008-06-19 | 2011-07-28 | Nicoll Steven B | Cellulosics for tissue replacement |
CA2734908A1 (en) | 2008-08-25 | 2010-03-11 | Amplimmune, Inc. | Compositions of pd-1 antagonists and methods of use |
US8889124B2 (en) | 2008-09-25 | 2014-11-18 | The Board Of Trustees Of The Leland Stanford Junior University | Tolerogenic populations of dendritic cells |
US8940331B2 (en) | 2008-11-22 | 2015-01-27 | The Board Of Trustees Of The Leland Stanford Junior University | Hydrogels, methods of making hydrogels, methods of using hydrogels, and methods of isolating, trapping, attracting, and/or killing cancer cells |
KR101132732B1 (ko) | 2008-11-26 | 2012-04-06 | 한국과학기술연구원 | 인 시튜 조직재생용 지능형 다공성 생분해 고분자 지지체 및 이의 제조방법 |
US8273373B2 (en) | 2008-12-30 | 2012-09-25 | Case Western Reserve University | Photocrosslinked biodegradable hydrogel |
AU2010203451B2 (en) | 2009-01-08 | 2016-06-30 | Albert Einstein College Of Medicine, Inc. | Bacterial vaccines with cell wall-associated ceramide-like glycolipids and uses thereof |
JP2010227012A (ja) | 2009-03-27 | 2010-10-14 | Seiko Epson Corp | がん細胞捕捉デバイス |
WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
US8551749B2 (en) | 2009-04-23 | 2013-10-08 | The Invention Science Fund I, Llc | Device including bone cage and method for treatment of disease in a subject |
US8728456B2 (en) | 2009-07-31 | 2014-05-20 | President And Fellows Of Harvard College | Programming of cells for tolerogenic therapies |
CN101655611B (zh) | 2009-09-11 | 2011-06-08 | 中国科学院长春应用化学研究所 | 一种具有双层杂化结构的反蛋白石水凝胶光子晶体的制备方法 |
CA2777162A1 (en) | 2009-10-09 | 2011-04-14 | Anaphore, Inc. | Polypeptides that bind il-23r |
EP2486132A1 (en) | 2009-10-09 | 2012-08-15 | Anaphore, Inc. | Combinatorial libraries based on c-type lectin domain |
US20110207166A1 (en) | 2009-11-06 | 2011-08-25 | Sarah Rivkah Vaiselbuh | Human bone marrow microenvironments and uses thereof |
CN102656119B (zh) | 2009-12-18 | 2015-11-25 | 花王株式会社 | 介孔二氧化硅颗粒的制造方法 |
JP5603063B2 (ja) | 2009-12-21 | 2014-10-08 | 花王株式会社 | 複合シリカ粒子の製造方法 |
CA2787376A1 (en) | 2010-01-19 | 2011-07-28 | President And Fellows Of Harvard College | Engineered opsonin for pathogen detection and treatment |
JP2013520203A (ja) | 2010-02-22 | 2013-06-06 | ル ラボグループ ソシエテ パール アクシオン サンプリフィエ | 天然運搬システムへの材料の封じ込め |
EP2542343B1 (en) | 2010-03-02 | 2017-11-08 | King Abdullah University Of Science And Technology | High surface area fibrous silica nanoparticles |
US20130052117A1 (en) | 2010-03-04 | 2013-02-28 | Keio University | Process for producing porous silica, and porous silica |
EP2542230A4 (en) | 2010-03-05 | 2013-08-28 | Harvard College | ENHANCEMENT OF SKELETAL MUSCLE STRAIN CELL GRAFT WITH DUAL DELIVERY OF VEGF AND IGF-1 |
CN102905732A (zh) | 2010-03-15 | 2013-01-30 | 弗罗桑医疗设备公司 | 用于促进止血和/或伤口愈合的方法 |
US20110300186A1 (en) | 2010-04-14 | 2011-12-08 | Battelle Memorial Institute | Functionalized Nano- and Micro-materials for Medical Therapies |
US20110256184A1 (en) | 2010-04-14 | 2011-10-20 | Battelle Memorial Institute | Non-ordered Mesoporous Silica Structure for Biomolecule Loading and Release |
EA030620B1 (ru) | 2010-05-26 | 2018-09-28 | Селекта Байосайенсиз, Инк. | Композиции для выработки иммунного ответа к наборам поверхностных антигенов, содержащие синтетические наноносители, и их применение |
GB201009273D0 (en) | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
EP2585053A4 (en) | 2010-06-25 | 2014-02-26 | Harvard College | COMMON RELEASE OF STIMULATING AND HEMMING FACTORS FOR THE PRODUCTION OF TEMPORARY STABILIZED AND SPATULARLY LIMITED ZONES |
CN103118678A (zh) | 2010-07-16 | 2013-05-22 | 约翰斯·霍普金斯大学 | 用于癌症免疫治疗的方法和组合物 |
WO2012019049A1 (en) | 2010-08-04 | 2012-02-09 | Georgia Tech Research Corporation | Devices, systems, and methods for excavating cancer cells |
EP2624873B1 (en) | 2010-10-06 | 2019-12-04 | President and Fellows of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
WO2012064697A2 (en) | 2010-11-08 | 2012-05-18 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
WO2012148684A1 (en) | 2011-04-27 | 2012-11-01 | President And Fellows Of Harvard College | Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation |
EP2701745B1 (en) | 2011-04-28 | 2018-07-11 | President and Fellows of Harvard College | Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration |
US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
CA3182519A1 (en) | 2011-04-29 | 2012-11-01 | Selecta Biosciences, Inc. | Tolerogenic synthetic nanocarriers for antigen-specific deletion of t effector cells |
US9486512B2 (en) | 2011-06-03 | 2016-11-08 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
ES2579855T3 (es) | 2011-06-24 | 2016-08-17 | Arqule, Inc. | Compuestos de imidazopiridinil-aminopiridina sustituidos |
SG10201608671SA (en) | 2011-07-18 | 2016-12-29 | Harvard College | Engineered Microbe-Targeting Molecules and Uses Thereof |
US20130145488A1 (en) | 2011-12-06 | 2013-06-06 | Iowa State University Research Foundation, Inc. | Mesoporous silica nanoparticles suitable for co-delivery |
AU2013207687B2 (en) | 2012-01-13 | 2017-11-30 | Dana-Farber Cancer Institute, Inc. | Controlled delivery of TLR agonists in structural polymeric devices |
NO2825156T3 (pt) | 2012-03-16 | 2017-12-23 | ||
HUE047973T2 (hu) | 2012-04-16 | 2020-05-28 | Harvard College | Mezoporózus szilíciumdioxid készítmények immunválaszok modulálására |
AU2013263349B2 (en) | 2012-05-17 | 2016-09-08 | Extend Biosciences, Inc | Carriers for improved drug delivery |
KR20150023811A (ko) | 2012-06-21 | 2015-03-05 | 컴퓨젠 엘티디. | 암의 치료를 위한 lsr 항체 및 그의 용도 |
US20140072510A1 (en) | 2012-09-13 | 2014-03-13 | Northwestern University | Synthetic Scaffolds for Metastasis Detection |
CN105209074A (zh) | 2012-10-20 | 2015-12-30 | 得克萨斯大学体系董事会 | 癌细胞陷阱 |
CA2902841A1 (en) | 2013-03-13 | 2014-10-02 | Creatics Llc | Methods and compositions for detecting pancreatic cancer |
AU2014268836B2 (en) | 2013-05-18 | 2018-08-02 | Aduro Biotech, Inc. | Compositions and methods for activating "stimulator of interferon gene"-dependent signalling |
AU2014268603B2 (en) | 2013-05-21 | 2018-03-22 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
WO2014190229A1 (en) | 2013-05-24 | 2014-11-27 | President And Fellows Of Harvard College | Methods of isolating microorganisms and uses thereof |
RU2672055C2 (ru) | 2013-11-01 | 2018-11-09 | Йейл Юниверсити | Модульные частицы для иммунотерапии |
ES2811301T3 (es) | 2014-04-04 | 2021-03-11 | Harvard College | Hidrogeles reticulados por química clic y métodos de uso |
US10682400B2 (en) | 2014-04-30 | 2020-06-16 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
US11065362B2 (en) | 2014-06-12 | 2021-07-20 | President And Fellows Of Harvard College | Viscoelastic hydrogels with fast stress relaxation |
US11229607B2 (en) | 2014-06-30 | 2022-01-25 | President And Fellows Of Harvard College | Hydrogel compositions comprising encapsulated cells and methods of use thereof |
WO2016123573A1 (en) | 2015-01-30 | 2016-08-04 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
WO2016161372A1 (en) | 2015-04-01 | 2016-10-06 | President And Fellows Of Harvard College | Immunoconjugates for programming or reprogramming of cells |
CN107708756A (zh) | 2015-04-10 | 2018-02-16 | 哈佛学院院长等 | 免疫细胞捕获装置及其制备和使用方法 |
US10435457B2 (en) | 2015-08-06 | 2019-10-08 | President And Fellows Of Harvard College | Microbe-binding molecules and uses thereof |
CN115487351A (zh) | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
US10813988B2 (en) | 2016-02-16 | 2020-10-27 | President And Fellows Of Harvard College | Pathogen vaccines and methods of producing and using the same |
EP3484448A4 (en) | 2016-07-13 | 2020-04-01 | President and Fellows of Harvard College | MIMETIC SCAFFOLDS OF CELLS HAVING ANTIGEN AND METHODS OF PREPARING AND USING THEM |
KR102638898B1 (ko) | 2016-08-02 | 2024-02-22 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 면역 반응을 조정하기 위한 생체재료 |
-
2006
- 2006-12-13 EP EP10194626.7A patent/EP2347774B1/en active Active
- 2006-12-13 ES ES10194565T patent/ES2804472T3/es active Active
- 2006-12-13 HU HUE10194565A patent/HUE051267T2/hu unknown
- 2006-12-13 SI SI200632379T patent/SI2347775T1/sl unknown
- 2006-12-13 PL PL10194565T patent/PL2347775T3/pl unknown
- 2006-12-13 AU AU2006326405A patent/AU2006326405B2/en active Active
- 2006-12-13 US US11/638,796 patent/US8067237B2/en active Active
- 2006-12-13 JP JP2008545829A patent/JP5539649B2/ja active Active
- 2006-12-13 AT AT06847667T patent/ATE534415T1/de active
- 2006-12-13 EP EP06847667A patent/EP1960009B1/en active Active
- 2006-12-13 WO PCT/US2006/047823 patent/WO2007070660A2/en active Application Filing
- 2006-12-13 DK DK10194565.7T patent/DK2347775T3/da active
- 2006-12-13 EP EP10194565.7A patent/EP2347775B1/en active Active
- 2006-12-13 CA CA2632630A patent/CA2632630C/en active Active
- 2006-12-13 PT PT101945657T patent/PT2347775T/pt unknown
-
2011
- 2011-11-28 US US13/305,088 patent/US8932583B2/en active Active
-
2013
- 2013-11-13 JP JP2013234787A patent/JP5976622B2/ja active Active
-
2014
- 2014-03-24 US US14/223,759 patent/US9132210B2/en active Active
-
2015
- 2015-06-25 US US14/750,423 patent/US9446107B2/en active Active
- 2015-07-14 JP JP2015140440A patent/JP6140222B2/ja active Active
-
2016
- 2016-03-30 US US15/085,858 patent/US20160271298A1/en not_active Abandoned
- 2016-04-21 US US15/135,207 patent/US10149897B2/en active Active
- 2016-04-21 US US15/135,213 patent/US10137184B2/en active Active
- 2016-12-26 JP JP2016250381A patent/JP6595446B2/ja active Active
-
2018
- 2018-10-25 US US16/170,313 patent/US11096997B2/en active Active
-
2019
- 2019-06-04 JP JP2019104265A patent/JP7065806B2/ja active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUE051267T2 (hu) | Sejttranszplantációs állványok | |
WO2009002401A3 (en) | Scaffolds for cell collection or elimination | |
WO2007145961A3 (en) | Microporous coating on medical devices | |
GB2445519B (en) | Copolymer and polymer light emitting device using the same | |
EP2409707B8 (en) | Polymer-based sustained release device | |
WO2009076592A3 (en) | Medical devices having porous component for controlled diffusion | |
TWI346253B (en) | Antireflection film composition, patterning process and substrate using the same | |
GB2447173B (en) | Polymer compound and polymer light emitting device using the same | |
EP2140883A4 (en) | NEW BASIS FOR A DRY SOLID DISPERSION, THE SOLID DISPERSION CONTAINING BASE, AND THE COMPOSITION CONTAINING THE DISPERSION | |
WO2009048645A3 (en) | Lipid coatings for implantable medical devices | |
EP2220705A4 (en) | SEPARATOR HAVING POROUS COATING LAYER AND ELECTROCHEMICAL DEVICE CONTAINING SAME | |
EP1972598A4 (en) | SILICA HOLLOW MICROPARTICLE, COMPOSITION FOR FORMING A TRANSPARENT COATING CONTAINING THE MICROPARTICLE AND SUBSTRATE HAVING A TRANSPARENT COATING | |
WO2009018037A3 (en) | Medical devices comprising porous inorganic fibers for the release of therapeutic agents | |
GB2432838B (en) | Light emitting polymer composition and polymer light emitting device | |
GB2437213B (en) | Polymer compound and polymer light emitting device using the same | |
UA90780C2 (ru) | Инсектицидная композиция бифентрина и обогащенного циперметрина (варианты) и способы борьбы с насекомыми | |
ATE510884T1 (de) | Polypropylenzusammensetzungen | |
WO2007092043A3 (en) | Bioactive material delivery systems comprising sol-gel compositions | |
TR200807139A2 (tr) | Suda taşinan aerosol bi̇leşi̇mi̇. | |
EP2151883A4 (en) | PHOTOELECTRIC CELL AND COATING AGENT FOR FORMING POROUS SEMICONDUCTOR FILM FOR PHOTOELECTRIC CELL | |
FR2910138B1 (fr) | Materiau electrolyte de dispositif electrocommandable, son procede de fabrication, dispositif electrocommandable le comprenant et procede de fabrication dudit dispositif | |
EP2128273A4 (en) | PRIMER SET FOR GENE AMPLIFICATION, GENE AMPLIFICATION REAGENT CONTAINING THE SAME, AND USE THEREOF | |
WO2008134475A3 (en) | Implant device release agents and methods of using same | |
GB2448459B (en) | Polymer compound and polymer light emitting device using the same | |
TW200700085A (en) | Endoparasiticidal compositions |