PT2252312E - Métodos de prevenção ou tratamento de resistência a insulina - Google Patents
Métodos de prevenção ou tratamento de resistência a insulina Download PDFInfo
- Publication number
- PT2252312E PT2252312E PT97072359T PT09707235T PT2252312E PT 2252312 E PT2252312 E PT 2252312E PT 97072359 T PT97072359 T PT 97072359T PT 09707235 T PT09707235 T PT 09707235T PT 2252312 E PT2252312 E PT 2252312E
- Authority
- PT
- Portugal
- Prior art keywords
- preventing
- methods
- insulin resistance
- treating insulin
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2688208P | 2008-02-07 | 2008-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2252312E true PT2252312E (pt) | 2014-07-17 |
Family
ID=40952720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97072359T PT2252312E (pt) | 2008-02-07 | 2009-02-06 | Métodos de prevenção ou tratamento de resistência a insulina |
Country Status (12)
Country | Link |
---|---|
US (7) | US8088727B2 (pt) |
EP (7) | EP3272353A1 (pt) |
JP (6) | JP5453320B2 (pt) |
CN (2) | CN101939019B (pt) |
CA (1) | CA2713150C (pt) |
CY (1) | CY1115305T1 (pt) |
DK (1) | DK2252312T3 (pt) |
ES (1) | ES2458870T3 (pt) |
PL (1) | PL2252312T3 (pt) |
PT (1) | PT2252312E (pt) |
SI (1) | SI2252312T1 (pt) |
WO (1) | WO2009100363A2 (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3167935B1 (en) | 2003-05-01 | 2018-07-18 | Cornell Research Foundation, Inc. | Method and carrier complexes for delivering molecules to cells |
CA2622911C (en) * | 2005-09-16 | 2016-12-06 | Cornell Research Foundation, Inc. | Methods for reducing cd36 expression |
ES2458870T3 (es) * | 2008-02-07 | 2014-05-07 | Cornell University | Procedimientos para prevenir o tratar la resistencia a la insulina |
EP2408463B1 (en) * | 2009-03-20 | 2016-10-19 | The General Hospital Corporation d/b/a Massachusetts General Hospital | D-arg-2'6'-dimethyltyrosine-lys-phe-nh2 for use in the prevention and treatment of burn injuries and secondary complications |
CN107412724A (zh) * | 2009-08-12 | 2017-12-01 | 康奈尔大学 | 预防或治疗代谢综合症的方法 |
PT3708178T (pt) | 2009-08-24 | 2023-11-16 | Stealth Biotherapeutics Inc | Peptídeo para uso ao prevenir ou tratar a degeneração macular |
EP2944317A1 (en) * | 2009-10-05 | 2015-11-18 | Cornell University | Methods for the prevention or treatment of heart failure |
WO2011082328A1 (en) * | 2009-12-31 | 2011-07-07 | Stealth Peptides International, Inc. | Methods for performing a coronary artery bypass graft procedure |
JP2013518057A (ja) * | 2010-01-25 | 2013-05-20 | コーネル ユニヴァーシティー | 芳香族カチオン性ペプチドおよびその使用 |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
GB201018125D0 (en) * | 2010-10-26 | 2010-12-08 | Marealis As | Peptide |
EP3009141A1 (en) * | 2011-12-09 | 2016-04-20 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
CN105343869A (zh) * | 2012-02-22 | 2016-02-24 | 康德生物医疗技术公司 | 用于预防或治疗眼科病状的方法和组合物 |
AU2013237827B2 (en) * | 2012-03-30 | 2017-12-14 | Stealth Biotherapeutics Inc. | Methods and compositions for the prevention and treatment neuropathy |
CA2880648A1 (en) * | 2012-08-02 | 2014-02-06 | Stealth Peptides International, Inc. | Methods for treatment of atherosclerosis |
JP2016506391A (ja) * | 2012-12-06 | 2016-03-03 | ステルス ペプチドズ インターナショナル インコーポレイテッド | ペプチド治療薬およびその使用方法 |
AU2017324510B2 (en) | 2016-09-07 | 2023-08-31 | Temple University - Of The Commonwealth System Of Higher Education | Compositions and methods for treatment of insulin resistance |
BR112020018010A2 (pt) | 2018-03-07 | 2020-12-29 | Temple University - Of The Commonwealth System Of Higher Education | Métodos de prevenção ou tratamento de diabetes tipo 2, de prevenção ou tratamento de pré-diabetes e de prevenção ou tratamento de uma condição em um indivíduo em necessidade |
US20200392075A1 (en) * | 2018-03-07 | 2020-12-17 | Temple University - Of The Commonwealth System Of Higher Education | Compositions and methods for treatment of insulin resistance |
CA3191819A1 (en) | 2020-09-09 | 2022-03-17 | Hazel Szeto | Methods and compositions for delivery of biotin to mitochondria |
US20240122884A1 (en) * | 2022-10-03 | 2024-04-18 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of n-lactoyl-phenylalanine and other n-lactoyl-amino acids |
Family Cites Families (40)
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NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
US5602100A (en) | 1988-06-30 | 1997-02-11 | Astra Ab | Dermorphin analogs having pharmacological activity |
ES2085865T3 (es) | 1988-06-30 | 1996-06-16 | Astra Ab | Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean. |
US5674980A (en) | 1989-12-21 | 1997-10-07 | Biogen Inc | Fusion protein comprising tat-derived transport moiety |
US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
IS4261A (is) | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
DE69630918T2 (de) | 1995-06-09 | 2004-10-28 | Hisamitsu Pharmaceutical Co., Inc., Tosu | Matrix für Iontophorese |
US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
US5885958A (en) | 1997-03-25 | 1999-03-23 | Administrators Of The Tulane Educational Fund | Mu-opiate receptor peptides |
US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
US6221355B1 (en) | 1997-12-10 | 2001-04-24 | Washington University | Anti-pathogen system and methods of use thereof |
US6268398B1 (en) | 1998-04-24 | 2001-07-31 | Mitokor | Compounds and methods for treating mitochondria-associated diseases |
CA2339218C (en) * | 1998-07-31 | 2008-10-28 | Mount Sinai Hospital | Methods and compositions for increasing insulin sensitivity |
US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
SE9900961D0 (sv) | 1999-03-16 | 1999-03-16 | Astra Ab | Novel compounds |
JP2003511362A (ja) | 1999-10-04 | 2003-03-25 | ユニバーシティー オブ メディシン アンド デンティストリー オブ ニュー ジャージー | 新規カルバメートおよび尿素類 |
US6759520B1 (en) | 1999-10-28 | 2004-07-06 | The New England Medical Center Hospitals, Inc. | Chimeric analgesic peptides |
US20050192215A1 (en) | 2000-01-21 | 2005-09-01 | Malabika Ghosh | Methods and materials relating to novel polypeptides and polynucleotides |
EP1303186B1 (en) | 2000-07-18 | 2011-01-26 | Cornell Research Foundation, Inc. | Medicinal uses of mu-opioid receptor agonists |
US6900178B2 (en) | 2000-09-12 | 2005-05-31 | University Of Kentucky Research Foundation | Protection against ischemia and reperfusion injury |
US20070015146A1 (en) | 2001-05-22 | 2007-01-18 | Gene Logic, Inc. | Molecular nephrotoxicology modeling |
EP2491943B1 (en) | 2003-02-04 | 2018-10-10 | Cornell Research Foundation, Inc. | Methods for preventing mitochondrial permeability transition |
EP3167935B1 (en) | 2003-05-01 | 2018-07-18 | Cornell Research Foundation, Inc. | Method and carrier complexes for delivering molecules to cells |
US7232824B2 (en) | 2003-09-30 | 2007-06-19 | Scios, Inc. | Quinazoline derivatives as medicaments |
RU2376028C2 (ru) | 2004-01-23 | 2009-12-20 | Корнелл Рисеч Фаундейшн, Инк. | Способ уменьшения окислительного повреждения (варианты) |
US20050272101A1 (en) | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
CA2622911C (en) * | 2005-09-16 | 2016-12-06 | Cornell Research Foundation, Inc. | Methods for reducing cd36 expression |
US20070259377A1 (en) * | 2005-10-11 | 2007-11-08 | Mickey Urdea | Diabetes-associated markers and methods of use thereof |
US20080027082A1 (en) | 2006-06-19 | 2008-01-31 | Berthold Hocher | Use of adenosine a1 antagonists in radiocontrast media induced nephropathy |
ES2458870T3 (es) * | 2008-02-07 | 2014-05-07 | Cornell University | Procedimientos para prevenir o tratar la resistencia a la insulina |
-
2009
- 2009-02-06 ES ES09707235.9T patent/ES2458870T3/es active Active
- 2009-02-06 PL PL09707235T patent/PL2252312T3/pl unknown
- 2009-02-06 EP EP17175315.5A patent/EP3272353A1/en not_active Withdrawn
- 2009-02-06 PT PT97072359T patent/PT2252312E/pt unknown
- 2009-02-06 CN CN200980104457.4A patent/CN101939019B/zh active Active
- 2009-02-06 WO PCT/US2009/033440 patent/WO2009100363A2/en active Application Filing
- 2009-02-06 EP EP18184266.7A patent/EP3441079A1/en not_active Withdrawn
- 2009-02-06 US US12/367,267 patent/US8088727B2/en active Active
- 2009-02-06 DK DK09707235.9T patent/DK2252312T3/da active
- 2009-02-06 CA CA2713150A patent/CA2713150C/en active Active
- 2009-02-06 SI SI200930975T patent/SI2252312T1/sl unknown
- 2009-02-06 EP EP16154315.2A patent/EP3103467A1/en not_active Withdrawn
- 2009-02-06 JP JP2010546063A patent/JP5453320B2/ja active Active
- 2009-02-06 EP EP14186864.6A patent/EP2902036A1/en not_active Withdrawn
- 2009-02-06 EP EP19191291.4A patent/EP3622963A1/en not_active Withdrawn
- 2009-02-06 CN CN201410273629.3A patent/CN104107417B/zh active Active
- 2009-02-06 EP EP13196962.8A patent/EP2712620A1/en not_active Withdrawn
- 2009-02-06 EP EP09707235.9A patent/EP2252312B1/en active Active
-
2011
- 2011-12-02 US US13/310,269 patent/US20120149638A1/en not_active Abandoned
-
2013
- 2013-07-19 US US13/946,921 patent/US20130303447A1/en not_active Abandoned
-
2014
- 2014-01-06 JP JP2014000640A patent/JP2014065738A/ja not_active Withdrawn
- 2014-07-02 CY CY20141100493T patent/CY1115305T1/el unknown
-
2015
- 2015-01-15 US US14/598,095 patent/US20150359839A1/en not_active Abandoned
- 2015-07-15 JP JP2015141367A patent/JP2015227353A/ja not_active Withdrawn
-
2016
- 2016-05-19 US US15/159,412 patent/US20170100450A1/en not_active Abandoned
- 2016-12-21 JP JP2016247623A patent/JP2017052801A/ja not_active Withdrawn
-
2017
- 2017-08-22 US US15/682,799 patent/US20180185435A1/en not_active Abandoned
-
2018
- 2018-02-27 JP JP2018033123A patent/JP2018090620A/ja active Pending
- 2018-10-09 US US16/155,333 patent/US20190269749A1/en not_active Abandoned
-
2019
- 2019-06-18 JP JP2019113087A patent/JP2019167384A/ja active Pending
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