PT1784402E - Derivados de pirrolo[3,2-c]piridina e processos para a sua preparação - Google Patents

Derivados de pirrolo[3,2-c]piridina e processos para a sua preparação Download PDF

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Publication number
PT1784402E
PT1784402E PT05781131T PT05781131T PT1784402E PT 1784402 E PT1784402 E PT 1784402E PT 05781131 T PT05781131 T PT 05781131T PT 05781131 T PT05781131 T PT 05781131T PT 1784402 E PT1784402 E PT 1784402E
Authority
PT
Portugal
Prior art keywords
pyrrolo
pyridine derivatives
processes
preparation
pharmaceutically acceptable
Prior art date
Application number
PT05781131T
Other languages
English (en)
Inventor
Jae-Gyu Kim
Byung-Nak Ahn
Hyouk-Woo Lee
Suk-Won Yoon
Young-Ae Yoon
Dong-Hoon Kim
Se-Hoon Keum
Young-Ah Shin
Heui-Il Kang
Ryong Choi
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of PT1784402E publication Critical patent/PT1784402E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT05781131T 2004-09-03 2005-09-03 Derivados de pirrolo[3,2-c]piridina e processos para a sua preparação PT1784402E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20040070536 2004-09-03

Publications (1)

Publication Number Publication Date
PT1784402E true PT1784402E (pt) 2011-08-23

Family

ID=36000316

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05781131T PT1784402E (pt) 2004-09-03 2005-09-03 Derivados de pirrolo[3,2-c]piridina e processos para a sua preparação

Country Status (17)

Country Link
US (2) US8148529B2 (pt)
EP (1) EP1784402B1 (pt)
JP (1) JP5126830B2 (pt)
KR (1) KR100946219B1 (pt)
CN (1) CN101018788B (pt)
AT (1) ATE518858T1 (pt)
AU (1) AU2005280738B2 (pt)
BR (1) BRPI0514843A (pt)
CA (1) CA2578880C (pt)
DK (1) DK1784402T3 (pt)
ES (1) ES2367312T3 (pt)
HK (1) HK1105977A1 (pt)
MX (1) MX2007002214A (pt)
PL (1) PL1784402T3 (pt)
PT (1) PT1784402E (pt)
RU (1) RU2378275C2 (pt)
WO (1) WO2006025714A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008017466A1 (en) * 2006-08-08 2008-02-14 Nycomed Gmbh Pharmaceutically active tetrahydroisoquinoline-substituted benzimidazole derivatives
WO2011004882A1 (ja) 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
GB2517908A (en) * 2013-08-14 2015-03-11 Kalvista Pharmaceuticals Ltd Bicyclic inhibitors
TWI636047B (zh) 2013-08-14 2018-09-21 英商卡爾維斯塔製藥有限公司 雜環衍生物
CN103626767A (zh) * 2013-12-04 2014-03-12 上海药明康德新药开发有限公司 区域选择性的氮杂吲哚及其合成方法
GB201421083D0 (en) 2014-11-27 2015-01-14 Kalvista Pharmaceuticals Ltd Enzyme inhibitors
CR20180233A (es) 2015-10-09 2018-05-25 Wave Life Sciences Ltd Composiciones oligonucleotídicas y sus métodos
KR102424709B1 (ko) 2016-05-31 2022-07-22 칼비스타 파마슈티컬즈 리미티드 혈장 칼리크레인 저해제로서 피라졸 유도체
GB201609607D0 (en) 2016-06-01 2016-07-13 Kalvista Pharmaceuticals Ltd Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts
PL3716952T3 (pl) 2017-11-29 2022-05-02 Kalvista Pharmaceuticals Limited Postacie dawkowania zawierające inhibitor kalikreiny osoczowej
GB201719881D0 (en) 2017-11-29 2018-01-10 Kalvista Pharmaceuticals Ltd Solid forms of plasma kallikrein inhibitor and salts thereof
WO2021028645A1 (en) 2019-08-09 2021-02-18 Kalvista Pharmaceuticals Limited Plasma kallikrein inhibitors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3269604D1 (en) 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
JP3465827B2 (ja) * 1993-02-24 2003-11-10 株式会社日清製粉グループ本社 アザインドール誘導体およびこれを有効成分とする抗潰瘍薬
ATE229020T1 (de) * 1994-01-19 2002-12-15 Sankyo Co Pyrrolopyridazin-derivate
DE69530989T2 (de) 1994-08-13 2004-05-19 Yuhan Corp. Neue pyrimidinderivate und verfahren zu ihrer herstellung
EP0849274A1 (en) * 1996-12-20 1998-06-24 Schering Aktiengesellschaft Bissteroidal compounds and their use for the preparation of chiral complexes
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
ZA99607B (en) * 1998-01-27 1999-07-27 Rhone Poulenc Rorer Pharma Substituted oxoazaheterocyclyl factor xa inhibitors.
CN1155598C (zh) 1998-09-23 2004-06-30 奥坦纳医药公司 四氢吡啶醚化合物
US20040110785A1 (en) * 2001-02-02 2004-06-10 Tao Wang Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
WO2003009852A1 (en) 2001-07-24 2003-02-06 Merck & Co., Inc. Tyrosine kinase inhibitors

Also Published As

Publication number Publication date
EP1784402A1 (en) 2007-05-16
ATE518858T1 (de) 2011-08-15
MX2007002214A (es) 2007-05-07
AU2005280738B2 (en) 2010-11-25
RU2007112108A (ru) 2008-10-10
AU2005280738A1 (en) 2006-03-09
KR20060051002A (ko) 2006-05-19
EP1784402B1 (en) 2011-08-03
BRPI0514843A (pt) 2008-06-24
PL1784402T3 (pl) 2011-12-30
CA2578880A1 (en) 2006-03-09
JP5126830B2 (ja) 2013-01-23
US8513277B2 (en) 2013-08-20
ES2367312T3 (es) 2011-11-02
EP1784402A4 (en) 2009-12-23
CN101018788B (zh) 2010-08-25
CA2578880C (en) 2013-01-29
RU2378275C2 (ru) 2010-01-10
US20120065224A1 (en) 2012-03-15
CN101018788A (zh) 2007-08-15
HK1105977A1 (en) 2008-02-29
KR100946219B1 (ko) 2010-03-08
JP2008511618A (ja) 2008-04-17
US20090005409A1 (en) 2009-01-01
WO2006025714A1 (en) 2006-03-09
US8148529B2 (en) 2012-04-03
DK1784402T3 (da) 2011-11-14

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