PT1562941E - Trans-9,10-desidroepotilona c e d, seus análogos e métodos de fabrico dos mesmos - Google Patents
Trans-9,10-desidroepotilona c e d, seus análogos e métodos de fabrico dos mesmos Download PDFInfo
- Publication number
- PT1562941E PT1562941E PT03768730T PT03768730T PT1562941E PT 1562941 E PT1562941 E PT 1562941E PT 03768730 T PT03768730 T PT 03768730T PT 03768730 T PT03768730 T PT 03768730T PT 1562941 E PT1562941 E PT 1562941E
- Authority
- PT
- Portugal
- Prior art keywords
- trans
- dehydroepothilone
- making
- methos
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42535202P | 2002-11-07 | 2002-11-07 | |
US47374303P | 2003-05-27 | 2003-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1562941E true PT1562941E (pt) | 2010-01-25 |
Family
ID=32314587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT03768730T PT1562941E (pt) | 2002-11-07 | 2003-11-07 | Trans-9,10-desidroepotilona c e d, seus análogos e métodos de fabrico dos mesmos |
Country Status (14)
Country | Link |
---|---|
US (2) | US20040152708A1 (pt) |
EP (3) | EP2135867B1 (pt) |
JP (3) | JP4641941B2 (pt) |
KR (2) | KR100966667B1 (pt) |
AT (1) | ATE452888T1 (pt) |
AU (1) | AU2003291337B2 (pt) |
CA (1) | CA2505368C (pt) |
CY (1) | CY1110295T1 (pt) |
DE (1) | DE60330703D1 (pt) |
DK (1) | DK1562941T3 (pt) |
ES (2) | ES2436296T3 (pt) |
PT (1) | PT1562941E (pt) |
SI (1) | SI1562941T1 (pt) |
WO (1) | WO2004043954A2 (pt) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999001124A1 (en) | 1996-12-03 | 1999-01-14 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto, analogues and uses thereof |
US8618085B2 (en) * | 2000-04-28 | 2013-12-31 | Koasn Biosciences Incorporated | Therapeutic formulations of desoxyepothilones |
US7649006B2 (en) | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
ES2336937T3 (es) | 2002-08-23 | 2010-04-19 | Sloan-Kettering Institute For Cancer Research | Sintesis de epotilonas, sus intermedios, analogos y usos. |
US7384964B2 (en) * | 2002-08-23 | 2008-06-10 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto, analogues and uses thereof |
CN101088998A (zh) * | 2002-11-07 | 2007-12-19 | 科桑生物科学公司 | 反式-9,10-脱氢埃坡霉素c和d,其类似物以及制备这些化合物的方法 |
WO2004043954A2 (en) * | 2002-11-07 | 2004-05-27 | Kosan Biosciences Incorporated | Trans-9,10-dehydroepothilone c and d, analogs thereof and methos of making the same |
MXPA05010388A (es) * | 2003-03-28 | 2006-03-08 | Kosan Biosciences Inc | Dispositivos, metodos y composiciones para prevenir la restenosis. |
KR20060122819A (ko) * | 2003-10-09 | 2006-11-30 | 코산 바이오사이언시즈, 인코포레이티드 | 치료학적 제형 |
US20050215604A1 (en) * | 2004-03-26 | 2005-09-29 | Kosan Biosciences, Inc. | Combination therapies with epothilones and carboplatin |
WO2008076904A1 (en) * | 2006-12-14 | 2008-06-26 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
US7981998B2 (en) * | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
CA2677045C (en) | 2007-01-31 | 2016-10-18 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
CN104086641A (zh) | 2007-02-23 | 2014-10-08 | 爱勒让治疗公司 | ***大环*** |
ES2430067T3 (es) | 2007-03-28 | 2013-11-18 | President And Fellows Of Harvard College | Polipéptidos cosidos |
US8030503B2 (en) | 2007-05-11 | 2011-10-04 | Kosan Biosciences Incorporated | Process for the preparation of epothilones |
US7955824B2 (en) * | 2007-05-11 | 2011-06-07 | Kosan Biosciences Incorporated | Methods of making epothilones |
US9175047B2 (en) | 2009-01-14 | 2015-11-03 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
EP2480565A4 (en) | 2009-09-22 | 2014-01-01 | Aileron Therapeutics Inc | PEPTIDOMIMETIC MACROCYCLES |
DK2603600T3 (da) | 2010-08-13 | 2019-03-04 | Aileron Therapeutics Inc | Peptidomimetiske makrocyklusser |
CA2852468A1 (en) | 2011-10-18 | 2013-04-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocyles |
CA2864120A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
NZ627528A (en) | 2012-02-15 | 2016-05-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
CA2776178A1 (en) | 2012-04-05 | 2013-10-05 | Hydro-Quebec | Ionic compounds |
WO2014071241A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
CN107106642B (zh) | 2014-09-24 | 2021-02-26 | 艾瑞朗医疗公司 | 拟肽大环化合物及其制剂 |
WO2016049359A1 (en) | 2014-09-24 | 2016-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
SG11201707750YA (en) | 2015-03-20 | 2017-10-30 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
JP2018528217A (ja) | 2015-09-10 | 2018-09-27 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | Mcl−1のモジュレーターとしてのペプチド模倣大環状分子 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69329073T2 (de) | 1992-03-23 | 2001-01-18 | Georgetown University Washingt | In liposomen verkapseltes taxol und verwendungsverfahren |
WO1994026254A1 (en) | 1993-05-17 | 1994-11-24 | The Liposome Company, Inc. | Incorporation of taxol into liposomes and gels |
US5415869A (en) | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
US5662883A (en) | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
US5534270A (en) | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
EP1683520B1 (en) | 1996-03-12 | 2013-11-20 | PG-TXL Company, L.P. | Water-soluble prodrugs |
US6458373B1 (en) | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
DK1052974T3 (da) | 1998-02-05 | 2009-08-10 | Novartis Ag | Farmaceutisk sammensætning indeholdende epothilon |
US6596875B2 (en) * | 2000-02-07 | 2003-07-22 | James David White | Method for synthesizing epothilones and epothilone analogs |
DE19954229A1 (de) * | 1999-11-04 | 2001-05-10 | Schering Ag | Epothilon-Derivate, Verfahren zu deren Herstellung und ihre pharmazeutische Verwendung |
DE19907480A1 (de) * | 1999-02-11 | 2000-08-17 | Schering Ag | Epothilon-Derivate, Verfahren zu deren Herstellung und ihre pharmazeutische Verwendung |
US6156373A (en) | 1999-05-03 | 2000-12-05 | Scimed Life Systems, Inc. | Medical device coating methods and devices |
EP1185301A1 (en) | 1999-05-24 | 2002-03-13 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
GB9918429D0 (en) | 1999-08-04 | 1999-10-06 | Novartis Ag | Organic compounds |
WO2001083800A2 (en) | 2000-04-28 | 2001-11-08 | Kosan Biosciences, Inc. | Heterologous production of polyketides |
AU2001266583A1 (en) * | 2000-05-26 | 2001-12-11 | Kosan Biosciences, Inc. | Epothilone derivatives and methods for making and using the same |
US6906188B2 (en) * | 2001-04-30 | 2005-06-14 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Method for synthesizing epothilones and epothilone analogs |
US20030176368A1 (en) * | 2001-09-06 | 2003-09-18 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto and analogues thereof |
US6921769B2 (en) * | 2002-08-23 | 2005-07-26 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
ES2336937T3 (es) * | 2002-08-23 | 2010-04-19 | Sloan-Kettering Institute For Cancer Research | Sintesis de epotilonas, sus intermedios, analogos y usos. |
US7649006B2 (en) * | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
WO2004043954A2 (en) * | 2002-11-07 | 2004-05-27 | Kosan Biosciences Incorporated | Trans-9,10-dehydroepothilone c and d, analogs thereof and methos of making the same |
-
2003
- 2003-11-07 WO PCT/US2003/035411 patent/WO2004043954A2/en active Application Filing
- 2003-11-07 EP EP09012671.5A patent/EP2135867B1/en not_active Expired - Lifetime
- 2003-11-07 ES ES09012671T patent/ES2436296T3/es not_active Expired - Lifetime
- 2003-11-07 SI SI200331732T patent/SI1562941T1/sl unknown
- 2003-11-07 DE DE60330703T patent/DE60330703D1/de not_active Expired - Lifetime
- 2003-11-07 KR KR1020057008039A patent/KR100966667B1/ko active IP Right Grant
- 2003-11-07 US US10/703,404 patent/US20040152708A1/en not_active Abandoned
- 2003-11-07 DK DK03768730.8T patent/DK1562941T3/da active
- 2003-11-07 AT AT03768730T patent/ATE452888T1/de active
- 2003-11-07 EP EP03768730A patent/EP1562941B1/en not_active Expired - Lifetime
- 2003-11-07 KR KR1020107000780A patent/KR100996996B1/ko not_active IP Right Cessation
- 2003-11-07 AU AU2003291337A patent/AU2003291337B2/en not_active Ceased
- 2003-11-07 CA CA2505368A patent/CA2505368C/en not_active Expired - Fee Related
- 2003-11-07 JP JP2005507102A patent/JP4641941B2/ja not_active Expired - Fee Related
- 2003-11-07 EP EP09012860A patent/EP2135868A1/en not_active Withdrawn
- 2003-11-07 ES ES03768730T patent/ES2336911T3/es not_active Expired - Lifetime
- 2003-11-07 PT PT03768730T patent/PT1562941E/pt unknown
-
2008
- 2008-07-11 US US12/172,174 patent/US20090186927A1/en not_active Abandoned
-
2010
- 2010-03-19 CY CY20101100250T patent/CY1110295T1/el unknown
- 2010-10-08 JP JP2010228356A patent/JP5679757B2/ja not_active Expired - Fee Related
-
2013
- 2013-07-16 JP JP2013147528A patent/JP2013213054A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2006510743A (ja) | 2006-03-30 |
US20090186927A1 (en) | 2009-07-23 |
SI1562941T1 (sl) | 2010-05-31 |
WO2004043954A3 (en) | 2004-11-18 |
JP2013213054A (ja) | 2013-10-17 |
KR20100018075A (ko) | 2010-02-16 |
ATE452888T1 (de) | 2010-01-15 |
ES2336911T3 (es) | 2010-04-19 |
DK1562941T3 (da) | 2010-04-19 |
DE60330703D1 (de) | 2010-02-04 |
JP4641941B2 (ja) | 2011-03-02 |
AU2003291337B2 (en) | 2010-09-09 |
JP2011006480A (ja) | 2011-01-13 |
CA2505368A1 (en) | 2004-05-27 |
KR100966667B1 (ko) | 2010-06-29 |
JP5679757B2 (ja) | 2015-03-04 |
ES2436296T3 (es) | 2013-12-30 |
KR100996996B1 (ko) | 2010-11-25 |
EP1562941A2 (en) | 2005-08-17 |
US20040152708A1 (en) | 2004-08-05 |
CA2505368C (en) | 2011-09-20 |
EP2135868A1 (en) | 2009-12-23 |
CY1110295T1 (el) | 2015-01-14 |
EP1562941B1 (en) | 2009-12-23 |
EP2135867B1 (en) | 2013-09-25 |
AU2003291337A1 (en) | 2004-06-03 |
KR20050084959A (ko) | 2005-08-29 |
EP2135867A1 (en) | 2009-12-23 |
WO2004043954A2 (en) | 2004-05-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1562941E (pt) | Trans-9,10-desidroepotilona c e d, seus análogos e métodos de fabrico dos mesmos | |
PL365613A1 (en) | Crystalline and pure modafinil, and process of preparing the same | |
EP1393220A4 (en) | METHOD FOR IDENTIFYING COMPARABLE INSTRUMENTS | |
AU2003288023A1 (en) | Process for the manufacture of 1,2-epoxy-3-chloropropane | |
AU2003296096A1 (en) | Gas producer | |
PL1664093T3 (pl) | Przeciwnowotworowe związki na bazie kahalalidu F | |
AU2003245663A1 (en) | Process for the enzymatic resolution of 1,3-dioxolane-4-carboxylates | |
AU2003240634A1 (en) | Method for producing bicalutamide | |
AU2003220279A1 (en) | Catalytic process for preparing perfluoroethanesulfonyl fluoride and/or perfluorodiethylsulfone | |
HK1081999A1 (en) | Microbiological method for the production of 7 alpha-substituted 11 alpha-hydrox-ysteroids | |
MXPA04004526A (es) | N-metil-homocisteinas, su uso y metodo para su produccion. | |
AU2003230639A1 (en) | Simplified methods of making 1,3-cyclohexadiene | |
TWI319707B (en) | Method of purifying pravastatin | |
EP1553073A4 (en) | PROCESS FOR PREPARING 1,2,4-BUTANTRIOL | |
MXPA03005400A (es) | Metodo para preparacion de 11 (12)-pentadecen-15-olidos. | |
EP1570049A4 (en) | 5-XANTHYLSURE PRODUCING MICROORGANISM | |
HUP0401390A3 (en) | Process for the manufacture of homopolyamide-4,6 fibers | |
AU2003283245A1 (en) | Method for the production of 1,6-hexanediol | |
IL161800A0 (en) | Method for the production of desclarithromycin, and intermediateproducts | |
AU2002356605A1 (en) | Method for producing 3,4-dihydroxybenzonitrile | |
AU2002321320A1 (en) | Method of preparing 2, 4, 6-triiodophenol | |
PL356465A1 (en) | METHOD OF MANUFACTURE OF 17beta-HYDROXY-7alpha-METHYL-19-NOR-17alpha-PREGN-5(10)-ENE-20-YNE-3-ONE | |
PL346255A1 (en) | Method of obtaining 5,6-dihydro-2-methyl-n-phenyl-1,4-oxathin-3-carboxamide | |
AU2001281828A1 (en) | Disubstituted 1,7-guanines | |
ZA200100309B (en) | Method for producing acrylic acid. |