PT1473036E - Solvato de hemitartarato de zolpidem - Google Patents
Solvato de hemitartarato de zolpidemInfo
- Publication number
- PT1473036E PT1473036E PT04010435T PT04010435T PT1473036E PT 1473036 E PT1473036 E PT 1473036E PT 04010435 T PT04010435 T PT 04010435T PT 04010435 T PT04010435 T PT 04010435T PT 1473036 E PT1473036 E PT 1473036E
- Authority
- PT
- Portugal
- Prior art keywords
- zolpidem
- hemitartarato
- solvato
- polymorphs
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Other Liquid Machine Or Engine Such As Wave Power Use (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Amplifiers (AREA)
- Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
- Suspension Of Electric Lines Or Cables (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19929800P | 2000-04-24 | 2000-04-24 | |
US20602500P | 2000-05-22 | 2000-05-22 | |
US22536400P | 2000-08-14 | 2000-08-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1473036E true PT1473036E (pt) | 2006-10-31 |
Family
ID=27394001
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT04010435T PT1473036E (pt) | 2000-04-24 | 2001-04-24 | Solvato de hemitartarato de zolpidem |
PT05001922T PT1541146E (pt) | 2000-04-24 | 2001-04-24 | Solvato de hemitartarato de zolpidem |
PT04010651T PT1475093E (pt) | 2000-04-24 | 2001-04-24 | Hemitartarato de zolpidem micronizado |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT05001922T PT1541146E (pt) | 2000-04-24 | 2001-04-24 | Solvato de hemitartarato de zolpidem |
PT04010651T PT1475093E (pt) | 2000-04-24 | 2001-04-24 | Hemitartarato de zolpidem micronizado |
Country Status (21)
Country | Link |
---|---|
US (8) | US20020077332A1 (pt) |
EP (1) | EP1292304B1 (pt) |
JP (3) | JP2003531173A (pt) |
KR (1) | KR20030069796A (pt) |
AT (4) | ATE338550T1 (pt) |
AU (2) | AU5721301A (pt) |
CA (1) | CA2406982A1 (pt) |
CZ (1) | CZ20023775A3 (pt) |
DE (7) | DE20122435U1 (pt) |
DK (1) | DK1292304T3 (pt) |
ES (4) | ES2238941T3 (pt) |
HR (1) | HRP20020909A2 (pt) |
HU (1) | HUP0300701A2 (pt) |
IL (1) | IL152411A0 (pt) |
NZ (1) | NZ522015A (pt) |
PL (1) | PL358548A1 (pt) |
PT (3) | PT1473036E (pt) |
SE (1) | SE5292304T3 (pt) |
SK (1) | SK16372002A3 (pt) |
WO (1) | WO2001080857A1 (pt) |
YU (1) | YU79402A (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001284322A1 (en) | 2000-08-29 | 2002-03-13 | Ranbaxy Laboratories Limited | Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem |
US6869970B2 (en) | 2002-02-04 | 2005-03-22 | Novartis Ag | Crystalline salt forms of valsartan |
DE60326270D1 (de) | 2002-12-18 | 2009-04-02 | Mallinckrodt Inc | Synthese von heteroaryl acetamiden |
WO2004087703A1 (en) * | 2003-03-12 | 2004-10-14 | Sun Pharmaceutical Industries Limited | Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide |
WO2005010002A1 (en) * | 2003-07-31 | 2005-02-03 | Ranbaxy Laboratories Limited | Process for the synthesis of zolpidem |
JP5179757B2 (ja) * | 2004-02-17 | 2013-04-10 | トランセプト ファーマシューティカルズ, インコーポレイティド | 口腔粘膜を介して催眠剤をデリバリーするための組成物及びその使用方法 |
WO2006008636A2 (en) * | 2004-07-16 | 2006-01-26 | Ranbaxy Laboratories Limited | Processes for the preparation of zolpidem and its hemitartrate |
US20070287740A1 (en) * | 2005-05-25 | 2007-12-13 | Transcept Pharmaceuticals, Inc. | Compositions and methods of treating middle-of-the night insomnia |
US20070225322A1 (en) * | 2005-05-25 | 2007-09-27 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the night insomnia |
US8242131B2 (en) * | 2005-05-25 | 2012-08-14 | Transcept Pharmaceuticals, Inc. | Methods of treating middle-of-the-night insomnia |
EP1928442B1 (en) * | 2005-08-19 | 2009-11-04 | Aventis Pharmaceuticals Inc. | Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof |
RU2008110477A (ru) * | 2005-08-19 | 2009-09-27 | Авентис Фармасьютикалз Инк. (Us) | Комбинация снотворного и r (+)-а-(2, 3-диметоксифенил)-1-[2-(4-фторфенил)этил]-4-пиперидинметанола и его терапевтическое применение |
WO2007040995A1 (en) * | 2005-10-03 | 2007-04-12 | Mallinckrodt Inc. | Process for preparing zolpidem hemitartrate and tartrate polymorphs |
JP2009511627A (ja) * | 2005-10-17 | 2009-03-19 | マリンクロッド・インコーポレイテッド | 錠剤マトリックスにおけるゾルピデムの多形転移 |
US20070098788A1 (en) * | 2005-10-28 | 2007-05-03 | Gore Subhash P | Non-benzodiazepine hypnotic compositions |
DE602007008545D1 (de) | 2006-03-31 | 2010-09-30 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyridine und pyrazine als modulatoren des histamin-h4-rezeptors |
US20080132535A1 (en) * | 2006-11-30 | 2008-06-05 | Transcept Pharmaceuticals, Inc. | Stabilized Zolpidem Pharmaceutical Compositions |
US20080145425A1 (en) * | 2006-12-15 | 2008-06-19 | Pliva Research & Development Limited | Pharmaceutical composition of zolpidem |
AU2009267159B2 (en) * | 2008-06-30 | 2014-05-15 | Janssen Pharmaceutica Nv | Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives |
US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
SG10201407881WA (en) | 2009-11-27 | 2015-01-29 | Genzyme Corp | An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase |
WO2011115069A1 (ja) * | 2010-03-19 | 2011-09-22 | 第一三共株式会社 | 結晶の網羅的探索 |
EP3660011A1 (en) | 2013-03-06 | 2020-06-03 | Janssen Pharmaceutica NV | Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4151273A (en) * | 1974-10-31 | 1979-04-24 | The Regents Of The University Of California | Increasing the absorption rate of insoluble drugs |
FR2408345A1 (fr) * | 1976-11-30 | 1979-06-08 | Besins Jean Louis | Nouvelle composition a action anti-conceptionnelle |
US4302446A (en) * | 1979-10-02 | 1981-11-24 | Bristol-Myers Company | Pharmaceutical compositions |
IT1130924B (it) * | 1980-03-06 | 1986-06-18 | Secifarma Spa | Procedimento per la preparazione di spironolattone micronizzato |
DE3018940A1 (de) * | 1980-05-17 | 1981-11-26 | Hoechst Ag, 6000 Frankfurt | Verwendung eines vinylchlorid-pfropf-copolymerisates in der plastisolverarbeitung |
FR2492382A1 (fr) * | 1980-10-22 | 1982-04-23 | Synthelabo | Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique |
FR2525601A1 (fr) * | 1982-04-21 | 1983-10-28 | Synthelabo | Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique |
US4675323A (en) * | 1985-08-06 | 1987-06-23 | Synthelabo | Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents |
SE457326B (sv) * | 1986-02-14 | 1988-12-19 | Lejus Medical Ab | Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa |
FR2600650B1 (fr) * | 1986-06-27 | 1988-09-09 | Synthelabo | Procede de preparation d'imidazopyridines et composes intermediaires |
FR2606410B1 (fr) * | 1986-11-07 | 1989-02-24 | Synthelabo | Imidazopyridines, leur preparation et leur application en therapeutique |
ES2026666T3 (es) * | 1987-03-27 | 1992-05-01 | Synthelabo | Procedimiento para preparar derivados de imidazopiridinas. |
US5271944A (en) * | 1991-04-05 | 1993-12-21 | Biofor, Ltd. | Pharmacologically enhanced formulations |
IT1276522B1 (it) * | 1995-04-07 | 1997-10-31 | Elena Benincasa | Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei |
DK1038875T3 (da) * | 1999-03-25 | 2003-09-29 | Synthon Bv | Imidazopyridine- derivativer og fremgangsmåde til fremstilling deraf |
ATE297924T1 (de) * | 1999-03-25 | 2005-07-15 | Synthon Bv | Zolpidem salze |
WO2001042239A1 (fr) * | 1999-12-13 | 2001-06-14 | Sumika Fine Chemicals Co., Ltd. | Procede de preparation d'un compose pyridinemethanol |
-
2001
- 2001-04-24 DE DE20122435U patent/DE20122435U1/de not_active Expired - Lifetime
- 2001-04-24 DE DE60122216T patent/DE60122216T2/de not_active Expired - Fee Related
- 2001-04-24 DE DE60125429T patent/DE60125429T2/de not_active Expired - Fee Related
- 2001-04-24 AT AT04010651T patent/ATE338550T1/de not_active IP Right Cessation
- 2001-04-24 DE DE60122944T patent/DE60122944T2/de not_active Expired - Fee Related
- 2001-04-24 JP JP2001577956A patent/JP2003531173A/ja not_active Withdrawn
- 2001-04-24 PT PT04010435T patent/PT1473036E/pt unknown
- 2001-04-24 EP EP01930705A patent/EP1292304B1/en not_active Revoked
- 2001-04-24 NZ NZ522015A patent/NZ522015A/en unknown
- 2001-04-24 ES ES04010435T patent/ES2238941T3/es not_active Expired - Lifetime
- 2001-04-24 AU AU5721301A patent/AU5721301A/xx active Pending
- 2001-04-24 HU HU0300701A patent/HUP0300701A2/hu unknown
- 2001-04-24 WO PCT/US2001/013175 patent/WO2001080857A1/en active IP Right Grant
- 2001-04-24 CZ CZ20023775A patent/CZ20023775A3/cs unknown
- 2001-04-24 AT AT01930705T patent/ATE308324T1/de not_active IP Right Cessation
- 2001-04-24 SK SK1637-2002A patent/SK16372002A3/sk not_active Application Discontinuation
- 2001-04-24 DE DE04010435T patent/DE04010435T1/de active Pending
- 2001-04-24 ES ES05001922T patent/ES2277301T3/es not_active Expired - Lifetime
- 2001-04-24 ES ES01930705T patent/ES2248321T3/es not_active Expired - Lifetime
- 2001-04-24 PL PL01358548A patent/PL358548A1/xx not_active Application Discontinuation
- 2001-04-24 DE DE60114617T patent/DE60114617T2/de not_active Expired - Fee Related
- 2001-04-24 AT AT04010435T patent/ATE335481T1/de not_active IP Right Cessation
- 2001-04-24 IL IL15241101A patent/IL152411A0/xx unknown
- 2001-04-24 CA CA002406982A patent/CA2406982A1/en not_active Abandoned
- 2001-04-24 AU AU2001257213A patent/AU2001257213B2/en not_active Ceased
- 2001-04-24 DK DK01930705T patent/DK1292304T3/da active
- 2001-04-24 SE SE01930705T patent/SE5292304T3/xx unknown
- 2001-04-24 AT AT05001922T patent/ATE348613T1/de not_active IP Right Cessation
- 2001-04-24 KR KR1020027014220A patent/KR20030069796A/ko not_active Application Discontinuation
- 2001-04-24 PT PT05001922T patent/PT1541146E/pt unknown
- 2001-04-24 YU YU79402A patent/YU79402A/sh unknown
- 2001-04-24 ES ES04010651T patent/ES2239558T3/es not_active Expired - Lifetime
- 2001-04-24 PT PT04010651T patent/PT1475093E/pt unknown
- 2001-04-24 DE DE04010651T patent/DE04010651T1/de active Pending
- 2001-04-24 US US09/841,025 patent/US20020077332A1/en not_active Abandoned
-
2002
- 2002-11-15 HR HR20020909A patent/HRP20020909A2/hr not_active Application Discontinuation
-
2004
- 2004-05-24 US US10/853,033 patent/US20040220211A1/en not_active Abandoned
- 2004-05-24 US US10/853,031 patent/US20040220210A1/en not_active Abandoned
- 2004-05-24 US US10/853,338 patent/US20040220212A1/en not_active Abandoned
- 2004-05-24 US US10/853,640 patent/US20040214859A1/en not_active Abandoned
- 2004-05-24 US US10/853,345 patent/US20040220213A1/en not_active Abandoned
- 2004-05-24 US US10/852,912 patent/US20040214858A1/en not_active Abandoned
-
2006
- 2006-02-09 JP JP2006033099A patent/JP2006137778A/ja active Pending
- 2006-06-27 JP JP2006177160A patent/JP2006249105A/ja active Pending
- 2006-10-25 US US11/588,122 patent/US20070037843A1/en not_active Abandoned
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