PT1322593E - Derivados o-substituidos de 6-metiltramadol - Google Patents

Derivados o-substituidos de 6-metiltramadol

Info

Publication number: PT1322593E
Authority: PT; Portugal
Prior art keywords: methyltramadol; derivatives; substituted; methyltramadol derivatives
Prior art date: 2000-09-29

Application number

PT01985699T

Other languages

English (en)

Inventor

Babette-Yvonne Koegel

Helmut Buschmann

Elmar Friderichs

Dagmar Kaulartz

Original Assignee

Gr Nenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-29

Filing date

2001-09-28

Publication date

2004-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7658871&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1322593(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-09-28 Application filed by Gr Nenthal Gmbh filed Critical Gr Nenthal Gmbh

2004-12-31 Publication of PT1322593E publication Critical patent/PT1322593E/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Psychology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Surgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

PT01985699T 2000-09-29 2001-09-28 Derivados o-substituidos de 6-metiltramadol PT1322593E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10049483A DE10049483A1 (de)	2000-09-29	2000-09-29	Substituierte 1-Aminobutan-3-ol-Derivate

Publications (1)

Publication Number	Publication Date
PT1322593E true PT1322593E (pt)	2004-12-31

Family

ID=7658871

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT01969791T PT1322592E (pt)	2000-09-29	2001-09-28	Derivados substituidos de 1-aminobutan-3-ol
PT01985699T PT1322593E (pt)	2000-09-29	2001-09-28	Derivados o-substituidos de 6-metiltramadol

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PT01969791T PT1322592E (pt)	2000-09-29	2001-09-28	Derivados substituidos de 1-aminobutan-3-ol

Country Status (29)

Country	Link
US (2)	US7022739B2 (pt)
EP (2)	EP1322593B1 (pt)
JP (2)	JP2004510755A (pt)
KR (2)	KR100864796B1 (pt)
CN (2)	CN1478067A (pt)
AR (1)	AR034158A1 (pt)
AT (2)	ATE272046T1 (pt)
AU (4)	AU8993701A (pt)
BR (2)	BR0114380A (pt)
CA (2)	CA2423903A1 (pt)
DE (3)	DE10049483A1 (pt)
DK (2)	DK1322592T4 (pt)
EC (2)	ECSP034532A (pt)
ES (2)	ES2225628T3 (pt)
HK (2)	HK1052924B (pt)
HU (2)	HUP0303195A3 (pt)
IL (2)	IL155106A0 (pt)
MX (2)	MXPA03002738A (pt)
NO (2)	NO20031387L (pt)
NZ (2)	NZ524976A (pt)
PE (1)	PE20020413A1 (pt)
PL (2)	PL361382A1 (pt)
PT (2)	PT1322592E (pt)
RU (2)	RU2286334C2 (pt)
SI (2)	SI1322593T1 (pt)
SK (2)	SK286727B6 (pt)
TR (2)	TR200402230T4 (pt)
WO (2)	WO2002026694A1 (pt)
ZA (2)	ZA200303220B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10049483A1 (de) *	2000-09-29	2002-05-02	Gruenenthal Gmbh	Substituierte 1-Aminobutan-3-ol-Derivate
ES2268095T3 (es)	2001-10-16	2007-03-16	Endo Pharmaceuticals Inc.	Uso de carbinoles para el tratamiento de la disfuncion neuropatica.
AU2003202495B2 (en) *	2002-01-11	2006-07-20	Sankyo Company, Limited	Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
US8128957B1 (en)	2002-02-21	2012-03-06	Valeant International (Barbados) Srl	Modified release compositions of at least one form of tramadol
US20050182056A9 (en) *	2002-02-21	2005-08-18	Seth Pawan	Modified release formulations of at least one form of tramadol
SI1685829T1 (sl)	2002-11-22	2008-08-31	Gruenenthal Gmbh	Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine
NZ549162A (en)	2004-02-24	2009-12-24	Sankyo Co	Amino-pyrrol alcohol compounds
NZ580429A (en) *	2007-05-31	2012-04-27	Sepracor Inc	Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
MX2011005788A (es) *	2008-12-05	2011-06-21	Arqule Inc	Inhibidores raf y sus usos.
ES2343050B1 (es) *	2008-12-16	2011-06-14	Chemo Iberica, S.A.	Procedimiento para la preparacion de desvenlafaxina y sus sales de adicion de acido farmaceuticamente aceptables.
WO2012100423A1 (en) *	2011-01-27	2012-08-02	Eli Lilly And Company	Analgesic compounds, methods, and formulations
JP2019502761A (ja) *	2016-01-21	2019-01-31	ラボラトリオスレヴィエセエレ	（（ｒ）−３−［（−１−メチルピロリジン−２−イル）メチル］−５−（２−フェニルスルホニルエチル）−１ｈ−インドールを作製する方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3652589A (en) *	1967-07-27	1972-03-28	Gruenenthal Chemie	1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
ZA732238B (en) *	1972-04-06	1974-01-30	American Home Prod	Benzylamine analgesics
US4155935A (en) *	1973-03-26	1979-05-22	American Home Products Corporation	Benzylamine analgesics
DE19525137C2 (de) *	1995-07-11	2003-02-27	Gruenenthal Gmbh	6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
US6017963A (en) *	1995-11-14	2000-01-25	Euro-Celtique, S.A.	Formulation for intranasal administration
DE19547766A1 (de) *	1995-12-20	1997-06-26	Gruenenthal Gmbh	1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
DE19601744C2 (de) *	1996-01-19	1998-04-16	Gruenenthal Gmbh	Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
DE19609847A1 (de) †	1996-03-13	1997-09-18	Gruenenthal Gmbh	Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
US5919826A (en) *	1996-10-24	1999-07-06	Algos Pharmaceutical Corporation	Method of alleviating pain
US6245804B1 (en) *	1997-05-30	2001-06-12	Schering Aktiengesellschaft	Nonsteroidal gestagens
DE69809055T2 (de) *	1997-07-15	2003-06-05	Russinsky Ltd., Cork	Verfahren zur herstellung von reinem cis-tramadol
CA2330142A1 (en) *	1998-05-22	1999-12-02	Mallinckrodt, Inc.	An improved synthesis and purification of (r,r)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride
ES2141688B1 (es) *	1998-11-06	2001-02-01	Vita Invest Sa	Nuevos esteres derivados de compuestos fenil-ciclohexil sustituidos.
DE19915601A1 (de) *	1999-04-07	2000-10-19	Gruenenthal Gmbh	3-Amino-3-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
MXPA02001820A (es) *	1999-08-20	2003-07-14	Johnson & Johnson	Composicion que comprende un material de tramadol y un farmaco anticonvulsivo.
PE20010623A1 (es) *	1999-10-05	2001-07-07	Gruenenthal Chemie	Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
US6339105B1 (en) *	1999-10-12	2002-01-15	Ortho-Mcneil Pharmaceutical, Inc.	Analgesic regimen
DE10000312A1 (de) *	2000-01-05	2001-07-12	Gruenenthal Gmbh	Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
DE10049483A1 (de) *	2000-09-29	2002-05-02	Gruenenthal Gmbh	Substituierte 1-Aminobutan-3-ol-Derivate
DE10048714A1 (de) *	2000-09-30	2002-04-11	Gruenenthal Gmbh	5-Amino-1-penlen-3-ol-Derivate
US6649783B2 (en) *	2001-10-03	2003-11-18	Euro-Celtique, S.A.	Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
US6780891B2 (en) *	2001-11-30	2004-08-24	Sepracor Inc.	Tramadol analogs and uses thereof

2000
- 2000-09-29 DE DE10049483A patent/DE10049483A1/de not_active Withdrawn
2001
- 2001-09-28 IL IL15510601A patent/IL155106A0/xx unknown
- 2001-09-28 PE PE2001000968A patent/PE20020413A1/es not_active Application Discontinuation
- 2001-09-28 MX MXPA03002738A patent/MXPA03002738A/es active IP Right Grant
- 2001-09-28 AU AU8993701A patent/AU8993701A/xx active Pending
- 2001-09-28 SI SI200130189T patent/SI1322593T1/xx unknown
- 2001-09-28 DK DK01969791T patent/DK1322592T4/da active
- 2001-09-28 JP JP2002532404A patent/JP2004510755A/ja active Pending
- 2001-09-28 AU AU2057802A patent/AU2057802A/xx active Pending
- 2001-09-28 AT AT01985699T patent/ATE272046T1/de not_active IP Right Cessation
- 2001-09-28 ES ES01985699T patent/ES2225628T3/es not_active Expired - Lifetime
- 2001-09-28 KR KR1020037004521A patent/KR100864796B1/ko not_active IP Right Cessation
- 2001-09-28 WO PCT/EP2001/011276 patent/WO2002026694A1/de active IP Right Grant
- 2001-09-28 MX MXPA03002737A patent/MXPA03002737A/es active IP Right Grant
- 2001-09-28 RU RU2003111756/04A patent/RU2286334C2/ru not_active IP Right Cessation
- 2001-09-28 EP EP01985699A patent/EP1322593B1/de not_active Expired - Lifetime
- 2001-09-28 ES ES01969791T patent/ES2225605T5/es not_active Expired - Lifetime
- 2001-09-28 RU RU2003111753/04A patent/RU2288219C2/ru not_active IP Right Cessation
- 2001-09-28 TR TR2004/02230T patent/TR200402230T4/xx unknown
- 2001-09-28 JP JP2002531080A patent/JP2004509939A/ja active Pending
- 2001-09-28 PT PT01969791T patent/PT1322592E/pt unknown
- 2001-09-28 DE DE50103035T patent/DE50103035D1/de not_active Expired - Lifetime
- 2001-09-28 WO PCT/EP2001/011231 patent/WO2002028817A1/de active IP Right Grant
- 2001-09-28 AR ARP010104583A patent/AR034158A1/es unknown
- 2001-09-28 BR BR0114380-8A patent/BR0114380A/pt not_active IP Right Cessation
- 2001-09-28 PL PL01361382A patent/PL361382A1/xx unknown
- 2001-09-28 DK DK01985699T patent/DK1322593T3/da active
- 2001-09-28 TR TR2004/02030T patent/TR200402030T4/xx unknown
- 2001-09-28 CA CA002423903A patent/CA2423903A1/en not_active Abandoned
- 2001-09-28 CA CA002423860A patent/CA2423860A1/en not_active Abandoned
- 2001-09-28 CN CNA018196454A patent/CN1478067A/zh active Pending
- 2001-09-28 NZ NZ524976A patent/NZ524976A/en unknown
- 2001-09-28 SI SI200130184T patent/SI1322592T1/xx unknown
- 2001-09-28 BR BR0114381-6A patent/BR0114381A/pt not_active IP Right Cessation
- 2001-09-28 PL PL01361632A patent/PL361632A1/xx not_active Application Discontinuation
- 2001-09-28 NZ NZ525171A patent/NZ525171A/en unknown
- 2001-09-28 PT PT01985699T patent/PT1322593E/pt unknown
- 2001-09-28 AU AU2002220578A patent/AU2002220578B2/en not_active Ceased
- 2001-09-28 AT AT01969791T patent/ATE272045T1/de active
- 2001-09-28 EP EP01969791A patent/EP1322592B2/de not_active Expired - Lifetime
- 2001-09-28 HU HU0303195A patent/HUP0303195A3/hu unknown
- 2001-09-28 AU AU2001289937A patent/AU2001289937B2/en not_active Ceased
- 2001-09-28 HU HU0303361A patent/HUP0303361A3/hu unknown
- 2001-09-28 IL IL15510501A patent/IL155105A0/xx unknown
- 2001-09-28 SK SK340-2003A patent/SK286727B6/sk not_active IP Right Cessation
- 2001-09-28 CN CNB018166067A patent/CN100391933C/zh not_active Expired - Fee Related
- 2001-09-28 DE DE50103036T patent/DE50103036D1/de not_active Expired - Lifetime
- 2001-09-28 SK SK338-2003A patent/SK3382003A3/sk not_active Application Discontinuation
- 2001-09-28 KR KR1020037004490A patent/KR100835549B1/ko not_active IP Right Cessation
2003
- 2003-03-26 NO NO20031387A patent/NO20031387L/no not_active Application Discontinuation
- 2003-03-26 NO NO20031382A patent/NO20031382L/no not_active Application Discontinuation
- 2003-03-28 US US10/401,020 patent/US7022739B2/en not_active Expired - Fee Related
- 2003-03-28 EC EC2003004532A patent/ECSP034532A/es unknown
- 2003-03-28 EC EC2003004530A patent/ECSP034530A/es unknown
- 2003-03-31 US US10/402,147 patent/US6828345B2/en not_active Expired - Fee Related
- 2003-04-24 ZA ZA200303220A patent/ZA200303220B/en unknown
- 2003-04-24 ZA ZA200303214A patent/ZA200303214B/en unknown
- 2003-07-16 HK HK03105140.5A patent/HK1052924B/zh not_active IP Right Cessation
- 2003-07-17 HK HK03105163.7A patent/HK1052925B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
US20030216393A1 (en)	2003-11-20
CN100391933C (zh)	2008-06-04
SK3402003A3 (en)	2003-09-11
NO20031382L (no)	2003-05-16
PE20020413A1 (es)	2002-05-18
CN1466567A (zh)	2004-01-07
JP2004510755A (ja)	2004-04-08
AR034158A1 (es)	2004-02-04
RU2286334C2 (ru)	2006-10-27
ES2225605T3 (es)	2005-03-16
SI1322592T1 (en)	2005-02-28
HK1052924B (zh)	2005-03-24
HUP0303361A2 (hu)	2004-03-01
NO20031387L (no)	2003-05-21
HUP0303195A3 (en)	2007-03-28
SK286727B6 (sk)	2009-04-06
MXPA03002738A (es)	2004-01-26
CA2423903A1 (en)	2003-03-27
ZA200303214B (en)	2004-08-31
ES2225628T3 (es)	2005-03-16
DK1322592T3 (da)	2004-11-22
KR20030059160A (ko)	2003-07-07
BR0114380A (pt)	2003-12-30
EP1322592A1 (de)	2003-07-02
US7022739B2 (en)	2006-04-04
ECSP034530A (es)	2003-05-26
DK1322592T4 (da)	2009-10-12
TR200402230T4 (tr)	2004-10-21
TR200402030T4 (tr)	2004-09-21
MXPA03002737A (es)	2004-01-26
HK1052924A1 (en)	2003-10-03
AU8993701A (en)	2002-04-15
NZ524976A (en)	2005-01-28
AU2057802A (en)	2002-04-08
HK1052925A1 (en)	2003-10-03
EP1322592B2 (de)	2009-06-17
US6828345B2 (en)	2004-12-07
KR100864796B1 (ko)	2008-10-23
HUP0303195A2 (hu)	2003-12-29
US20030220389A1 (en)	2003-11-27
PL361382A1 (en)	2004-10-04
EP1322593A1 (de)	2003-07-02
HK1052925B (zh)	2005-04-01
NZ525171A (en)	2006-02-24
ZA200303220B (en)	2004-08-19
BR0114381A (pt)	2003-12-30
AU2001289937B2 (en)	2007-01-18
ES2225605T5 (es)	2009-11-18
ATE272046T1 (de)	2004-08-15
KR20030077531A (ko)	2003-10-01
SK3382003A3 (en)	2003-08-05
NO20031387D0 (no)	2003-03-26
PL361632A1 (en)	2004-10-04
CN1478067A (zh)	2004-02-25
EP1322593B1 (de)	2004-07-28
IL155105A0 (en)	2003-10-31
SI1322593T1 (en)	2004-12-31
ECSP034532A (es)	2003-05-26
HUP0303361A3 (en)	2007-03-28
DE50103035D1 (de)	2004-09-02
PT1322592E (pt)	2004-12-31
DK1322593T3 (da)	2004-10-11
ATE272045T1 (de)	2004-08-15
DE50103036D1 (de)	2004-09-02
AU2002220578B2 (en)	2006-11-30
DE10049483A1 (de)	2002-05-02
JP2004509939A (ja)	2004-04-02
KR100835549B1 (ko)	2008-06-09
RU2288219C2 (ru)	2006-11-27
WO2002028817A1 (de)	2002-04-11
NO20031382D0 (no)	2003-03-26
EP1322592B1 (de)	2004-07-28
CA2423860A1 (en)	2003-03-27
WO2002026694A1 (de)	2002-04-04
IL155106A0 (en)	2003-10-31

Publication	Publication Date	Title
DK1292604T3 (da)	2009-06-15	2-Aminocarbonyl-9H-purinderivater
DK1226127T3 (da)	2009-10-19	Substituerede phenylsulfamoylcarboxamider
PT1303521E (pt)	2005-05-31	Derivados de tetra-hidro-heterocicloazepinil-pirimidina
DK1255740T3 (da)	2006-02-06	Substituerede arylpyraziner
ATE298332T1 (de)	2005-07-15	Decahydro-isochinolinderivate
AR028393A1 (es)	2003-05-07	Iminoazidas substituidas
DK1280809T3 (da)	2005-11-07	Antitumorecteinascidinderivater
ATE334114T1 (de)	2006-08-15	Substituierte c-cyclohexylmethylamin-derivate
AR028602A1 (es)	2003-05-14	Derivados de pirrol
AR028282A1 (es)	2003-04-30	Derivados de aminofenil pirimidona
PT1322593E (pt)	2004-12-31	Derivados o-substituidos de 6-metiltramadol
ATE365721T1 (de)	2007-07-15	Substituierte benzoylcyclohexenone
AR028302A1 (es)	2003-05-07	Feniluracilos substituidos
ATE282021T1 (de)	2004-11-15	Substituierte aminomethyl-phenyl- cyclohexanderivate
PT1351959E (pt)	2005-09-30	Novos derivados de pleuromutilina
PT1246791E (pt)	2005-03-31	Derivados de aminometilfenilciclo-hexanona
DK1322590T3 (da)	2007-09-03	Substituerede 5-amino-1-penten-3-ol-derivater
ATE374776T1 (de)	2007-10-15	Pyrrolotriazolopyrimidinonderivate
NO20024393D0 (no)	2002-09-13	2-fenylpyran-4-on-derivater
DK1246793T3 (da)	2005-02-21	Substituerede aminomethyl-phenyl-cyclohexanderivater