PT1317430E - Derivados de (2-azabiciclo[2.2.1]hepta-7-il)-metanol como agonistas do receptor nocotinico de acetilcolina - Google Patents
Derivados de (2-azabiciclo[2.2.1]hepta-7-il)-metanol como agonistas do receptor nocotinico de acetilcolinaInfo
- Publication number
- PT1317430E PT1317430E PT01965274T PT01965274T PT1317430E PT 1317430 E PT1317430 E PT 1317430E PT 01965274 T PT01965274 T PT 01965274T PT 01965274 T PT01965274 T PT 01965274T PT 1317430 E PT1317430 E PT 1317430E
- Authority
- PT
- Portugal
- Prior art keywords
- nocotine
- acetilcoline
- hepta
- azabicyclo
- receptor agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10044905A DE10044905A1 (de) | 2000-09-12 | 2000-09-12 | (2-Azabicyclo[2.2.1]hept-7-yl)methanol-Derivate als nikontinische Acetylcholinrezeptor Agonisten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1317430E true PT1317430E (pt) | 2005-09-30 |
Family
ID=7655825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01965274T PT1317430E (pt) | 2000-09-12 | 2001-09-11 | Derivados de (2-azabiciclo[2.2.1]hepta-7-il)-metanol como agonistas do receptor nocotinico de acetilcolina |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7008955B2 (pt) |
| EP (1) | EP1317430B1 (pt) |
| JP (1) | JP2004509106A (pt) |
| CN (1) | CN1455770A (pt) |
| AR (1) | AR034557A1 (pt) |
| AT (1) | ATE295835T1 (pt) |
| AU (1) | AU2001285945A1 (pt) |
| CA (1) | CA2421936A1 (pt) |
| DE (2) | DE10044905A1 (pt) |
| ES (1) | ES2240506T3 (pt) |
| HU (1) | HUP0302971A2 (pt) |
| MX (1) | MXPA03002076A (pt) |
| PT (1) | PT1317430E (pt) |
| WO (1) | WO2002022578A1 (pt) |
| ZA (1) | ZA200302829B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10118551A1 (de) * | 2001-04-14 | 2002-10-17 | Merck Patent Gmbh | Nikotinische Acetylcholinrezeptor Liganden |
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| BR0307714A (pt) * | 2002-02-15 | 2005-02-09 | Upjohn Co | Benzoilamidas substituìdas com azabiciclo e tioamidas para tratamento de distúrbios relacionados ao cns |
| MXPA05010496A (es) * | 2003-03-28 | 2005-11-16 | Pharmacia & Upjohn Co Llc | Moduladores alostericos positivos del receptor de acetilcolina nicotinico. |
| TR201807944T4 (tr) | 2008-11-19 | 2018-06-21 | Forum Pharmaceuticals Inc | (R)-7-kloro-N-(kinüklidin-3-il)benzo[b]tiyofen-2-karboksamit ve bunun farmasötik olarak kabul edilebilir tuzları ile şizofreninin negatif belirtilerinin tedavisi. |
| JP5808319B2 (ja) * | 2009-05-11 | 2015-11-10 | フォルム ファーマシューティカルズ、インコーポレイテッド | アセチルコリンエステラーゼ阻害剤と組み合わせた特定のα７ニコチン酸受容体を用いた認知障害の治療 |
| ES2746850T3 (es) | 2010-05-17 | 2020-03-09 | Forum Pharmaceuticals Inc | Formulaciones farmacéuticas que comprenden formas cristalinas de clorhidrato de (R)-7-cloro-N-(quinuclidin-3-il)benzo(b)tiofeno-2-carboxamida monohidratado |
| MX358512B (es) | 2012-05-08 | 2018-08-24 | Forum Pharmaceuticals Inc | Uso de (r)-7cloro-n-(quinuclidin-3-il) benzo[b] tiofeno-2-carboxamida o una sal farmacéuticamente aceptable de la misma para preparar una composición farmacéutica en el tratamiento de una disfunción cognitiva. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9020051D0 (en) * | 1990-09-13 | 1990-10-24 | Pfizer Ltd | Muscarinic receptor antagonists |
| US5817679A (en) * | 1993-04-01 | 1998-10-06 | University Of Virginia | 7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands |
| US6117889A (en) * | 1994-04-01 | 2000-09-12 | University Of Virginia | 7-Azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents |
| WO1998048801A1 (fr) * | 1997-04-26 | 1998-11-05 | Sumitomo Pharmaceuticals Co., Ltd. | Composes 2-azabicyclo |
| GB9822945D0 (en) * | 1998-10-20 | 1998-12-16 | Isis Innovations Ltd | Epibatidine analogues |
-
2000
- 2000-09-12 DE DE10044905A patent/DE10044905A1/de not_active Withdrawn
-
2001
- 2001-09-11 CA CA002421936A patent/CA2421936A1/en not_active Abandoned
- 2001-09-11 AT AT01965274T patent/ATE295835T1/de not_active IP Right Cessation
- 2001-09-11 DE DE50106266T patent/DE50106266D1/de not_active Expired - Fee Related
- 2001-09-11 MX MXPA03002076A patent/MXPA03002076A/es not_active Application Discontinuation
- 2001-09-11 CN CN01815520A patent/CN1455770A/zh active Pending
- 2001-09-11 HU HU0302971A patent/HUP0302971A2/hu unknown
- 2001-09-11 PT PT01965274T patent/PT1317430E/pt unknown
- 2001-09-11 JP JP2002526831A patent/JP2004509106A/ja active Pending
- 2001-09-11 WO PCT/EP2001/010491 patent/WO2002022578A1/de active IP Right Grant
- 2001-09-11 EP EP01965274A patent/EP1317430B1/de not_active Expired - Lifetime
- 2001-09-11 US US10/380,064 patent/US7008955B2/en not_active Expired - Fee Related
- 2001-09-11 ES ES01965274T patent/ES2240506T3/es not_active Expired - Lifetime
- 2001-09-11 AU AU2001285945A patent/AU2001285945A1/en not_active Abandoned
- 2001-09-12 AR ARP010104304A patent/AR034557A1/es unknown
-
2003
- 2003-04-10 ZA ZA200302829A patent/ZA200302829B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004509106A (ja) | 2004-03-25 |
| US20040039045A1 (en) | 2004-02-26 |
| DE10044905A1 (de) | 2002-03-21 |
| MXPA03002076A (es) | 2003-06-24 |
| EP1317430A1 (de) | 2003-06-11 |
| HUP0302971A2 (hu) | 2003-12-29 |
| ATE295835T1 (de) | 2005-06-15 |
| CA2421936A1 (en) | 2003-03-11 |
| ZA200302829B (en) | 2004-08-13 |
| US7008955B2 (en) | 2006-03-07 |
| WO2002022578A1 (de) | 2002-03-21 |
| EP1317430B1 (de) | 2005-05-18 |
| AU2001285945A1 (en) | 2002-03-26 |
| ES2240506T3 (es) | 2005-10-16 |
| CN1455770A (zh) | 2003-11-12 |
| DE50106266D1 (en) | 2005-06-23 |
| AR034557A1 (es) | 2004-03-03 |
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