PT1146896E - Formulacoes monodispersas de analogo acilado e hexamerico insulina - Google Patents
Formulacoes monodispersas de analogo acilado e hexamerico insulinaInfo
- Publication number
- PT1146896E PT1146896E PT00904496T PT00904496T PT1146896E PT 1146896 E PT1146896 E PT 1146896E PT 00904496 T PT00904496 T PT 00904496T PT 00904496 T PT00904496 T PT 00904496T PT 1146896 E PT1146896 E PT 1146896E
- Authority
- PT
- Portugal
- Prior art keywords
- formulations
- human insulin
- modified
- acylated
- monodispersas
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11729199P | 1999-01-26 | 1999-01-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1146896E true PT1146896E (pt) | 2002-10-31 |
Family
ID=22372048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00904496T PT1146896E (pt) | 1999-01-26 | 2000-01-26 | Formulacoes monodispersas de analogo acilado e hexamerico insulina |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1146896B1 (pt) |
JP (1) | JP2002535287A (pt) |
AT (1) | ATE220917T1 (pt) |
AU (1) | AU2624400A (pt) |
DE (1) | DE60000288T2 (pt) |
DK (1) | DK1146896T3 (pt) |
ES (1) | ES2180511T3 (pt) |
PT (1) | PT1146896E (pt) |
WO (1) | WO2000043034A2 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7060675B2 (en) * | 2001-02-15 | 2006-06-13 | Nobex Corporation | Methods of treating diabetes mellitus |
US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
AU2003218635A1 (en) * | 2002-05-07 | 2003-11-11 | Novo Nordisk A/S | Soluble formulations comprising insulin aspart and insulin detemir |
DE60335797D1 (de) | 2002-05-07 | 2011-03-03 | Novo Nordisk As | Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten |
US7648962B2 (en) | 2002-11-26 | 2010-01-19 | Biocon Limited | Natriuretic compounds, conjugates, and uses thereof |
BR0316560A (pt) | 2002-11-26 | 2005-10-04 | Nobex Corp | Conjugado de composto natriurético, formulação farmacêutica, método de tratar uma condição, método de preparação do conjugado de composto natriurético, conjugado de peptìdeo pró-polinatriurético modificado, análogo de peptìdeo natriurético, análogo de hbnp, composto, e, método de preparar um composto |
PL1773878T3 (pl) * | 2004-07-19 | 2015-07-31 | Biocon Ltd | Koniugaty insulina-oligomer, ich formulacje i zastosowania |
EP2505593A1 (en) | 2005-12-28 | 2012-10-03 | Novo Nordisk A/S | Compositions comprising an acylated insulin and zinc and method of making the said compositions |
WO2008015099A2 (en) | 2006-07-31 | 2008-02-07 | Novo Nordisk A/S | Pegylated, extended insulins |
HUE029512T2 (en) | 2006-09-22 | 2017-03-28 | Novo Nordisk As | Protease Resistant Insulin Analogs |
JP5496082B2 (ja) | 2007-04-30 | 2014-05-21 | ノボ・ノルデイスク・エー/エス | タンパク質組成物を乾燥させる方法、乾燥タンパク質組成物、及び乾燥タンパク質を含有する薬学的組成物 |
US9034818B2 (en) | 2007-06-13 | 2015-05-19 | Novo Nordisk A/S | Pharmaceutical formulations comprising an insulin derivative |
CN101970477B (zh) | 2008-03-14 | 2014-12-31 | 诺沃-诺迪斯克有限公司 | 蛋白酶稳定的胰岛素类似物 |
PL2910570T3 (pl) | 2008-03-18 | 2017-06-30 | Novo Nordisk A/S | Stabilizowane względem proteaz, acylowane analogi insuliny |
EP2352513B1 (en) | 2008-10-30 | 2016-09-14 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
RU2013123515A (ru) | 2010-10-27 | 2014-12-10 | Ново Нордиск А/С | Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами |
CA2870313A1 (en) | 2012-04-11 | 2013-10-17 | Novo Nordisk A/S | Insulin formulations |
ES2670969T3 (es) | 2012-11-13 | 2018-06-04 | Adocia | Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido |
EP2991672A1 (en) | 2013-04-30 | 2016-03-09 | Novo Nordisk A/S | Novel administration regime |
MX366636B (es) | 2013-10-07 | 2019-07-17 | Novo Nordisk As | Nuevo derivado de un análogo de insulina. |
TW201630622A (zh) | 2014-12-16 | 2016-09-01 | 美國禮來大藥廠 | 速效胰島素組合物 |
JO3749B1 (ar) | 2015-08-27 | 2021-01-31 | Lilly Co Eli | تركيبات إنسولين سريعة المفعول |
RU2758367C2 (ru) | 2016-12-16 | 2021-10-28 | Ново Нордиск А/С | Фармацевтические композиции, содержащие инсулин |
AU2018275545B2 (en) | 2017-06-01 | 2021-02-04 | Eli Lilly And Company | Rapid-acting insulin compositions |
AU2018317810A1 (en) | 2017-08-17 | 2020-03-19 | Novo Nordisk A/S | Novel acylated insulin analogues and uses thereof |
US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
WO2021033066A1 (en) * | 2019-08-16 | 2021-02-25 | Lamark Biotech Pvt Limited | A formulation of insulin based on crystal-seeding in hydrogels and method thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1120019C (zh) * | 1996-06-20 | 2003-09-03 | 诺沃挪第克公司 | 含NaCl的胰岛素制品 |
DE69829953T2 (de) * | 1997-02-07 | 2006-03-02 | Novo Nordisk A/S | Kristallisation von proteinen |
EP1044016B1 (en) * | 1998-01-09 | 2005-03-16 | Novo Nordisk A/S | Stabilised insulin compositions |
-
2000
- 2000-01-26 PT PT00904496T patent/PT1146896E/pt unknown
- 2000-01-26 AU AU26244/00A patent/AU2624400A/en not_active Abandoned
- 2000-01-26 DK DK00904496T patent/DK1146896T3/da active
- 2000-01-26 AT AT00904496T patent/ATE220917T1/de not_active IP Right Cessation
- 2000-01-26 WO PCT/US2000/001627 patent/WO2000043034A2/en active IP Right Grant
- 2000-01-26 EP EP00904496A patent/EP1146896B1/en not_active Expired - Lifetime
- 2000-01-26 JP JP2000594487A patent/JP2002535287A/ja not_active Withdrawn
- 2000-01-26 ES ES00904496T patent/ES2180511T3/es not_active Expired - Lifetime
- 2000-01-26 DE DE60000288T patent/DE60000288T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1146896A2 (en) | 2001-10-24 |
ATE220917T1 (de) | 2002-08-15 |
DE60000288T2 (de) | 2003-01-16 |
DK1146896T3 (da) | 2002-09-02 |
JP2002535287A (ja) | 2002-10-22 |
WO2000043034A3 (en) | 2000-12-28 |
WO2000043034A2 (en) | 2000-07-27 |
ES2180511T3 (es) | 2003-02-16 |
EP1146896B1 (en) | 2002-07-24 |
DE60000288D1 (de) | 2002-08-29 |
AU2624400A (en) | 2000-08-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1146896E (pt) | Formulacoes monodispersas de analogo acilado e hexamerico insulina | |
AU582920B2 (en) | Continuous release pharmaceutical compositions | |
WO2002043750A3 (en) | Method for the stabilizing of biomolecules (e.g. insulin) in liquid formulations | |
EP1234586A3 (en) | Hepatoselective pharmaceutical actives | |
EP1808438A3 (en) | Purification and stabilization of peptide and proteins in pharmaceutical agents | |
EP2308963A3 (en) | System for processing lipoaspirate cells | |
BR9607647A (pt) | Derivado de insulina e composição farmacêutica e processo para o tratamento de diabetes em um paciente em necessidade deste tratamento | |
DE58901401D1 (de) | Pharmazeutische zubereitung zur behandlung des diabetes mellitus. | |
ATE107514T1 (de) | Stabilisierte protein- oder peptidkonjugate. | |
DK0969843T3 (da) | Antitussive formuleringer indeholdende theobromin | |
IL207923A0 (en) | Metal-binding compounds and uses therefor | |
BR9811755A (pt) | Peptìdeo, processo para o tratamento da obesidade em um animal, uso de um peptìdeo, e, composição farmacêutica | |
HK1046242A1 (en) | Preparations for the application of anti-inflammatory agents. | |
CA2522146A1 (en) | Uptake of macromolecules | |
WO1996032134A3 (de) | Konjugat aus einem wirkstoff, einem polyether und ggf. einem nicht als körperfremd angesehenen, nativen protein | |
DE69816808D1 (de) | Somatostatin agoniste zur reduzierung von körpergewicht | |
DE69734349D1 (de) | Behandlung von knochenleiden mit adrenomedullin | |
Yaegaki et al. | The effect of mouthwash on oral malodour production | |
WO2001045714A3 (en) | Formulations of adenosine a1 agonists | |
MD950010A (ro) | Compoziţie pentru înlăturarea sau dezactivarea componentelor dăunătoare în sînge sau alte lichide extracelulare ale organismului şi procedeu de obţinere | |
PT97878A (pt) | Processo para a preparacao de uma composicao farmaceutica para uso oftalmico contendo hexetidina ou seus derivados ou sais | |
UA28283A (uk) | Природний лікувальний засіб | |
MX9704388A (es) | Incremento de la concentracion de creatina y glicogeno en musculos. | |
UA37377A (uk) | Спосіб отримання мазі для лікування захворювань, які викликані внутрішньоклітинними інфекційними агентами | |
MX9800126A (es) | Utilizacion en una composicion de un extracto de al menos una labiada. |