PL430624A1 - Multi-compartment capsule-in-capsule system for encapsulating peptides - Google Patents
Multi-compartment capsule-in-capsule system for encapsulating peptidesInfo
- Publication number
- PL430624A1 PL430624A1 PL430624A PL43062419A PL430624A1 PL 430624 A1 PL430624 A1 PL 430624A1 PL 430624 A PL430624 A PL 430624A PL 43062419 A PL43062419 A PL 43062419A PL 430624 A1 PL430624 A1 PL 430624A1
- Authority
- PL
- Poland
- Prior art keywords
- capsule
- compartment
- water
- peptides
- encapsulating
- Prior art date
Links
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Przedmiotem niniejszego wynalazku jest wieloprzedziałowy układ typu kapsuła w kapsule do enkapsulacji peptydów na bazie pochodnej kwasu hialuronowego, którego stabilizacja nie wymaga użycia surfaktantów, emulsyfikatorów i/lub stabilizatorów, pełniący rolę nośnika, który rozwiązuje problem ochrony wrażliwych substancji hydrofilowych przed agresywnym środowiskiem zewnętrznym, w tym degradacją i dezaktywacją, ale nie ograniczony do białek, a także umożliwia jednoczesne podawanie substancji aktywnych o różnej hydrofilowości. Przedmiotem wynalazku jest również sposób otrzymywania wieloprzedziałowego układu typu "kapsuła w kapsule" w formie podwójnej emulsji typu woda-olej-woda oraz zastosowanie wieloprzedziałowego do leczenia cukrzycy typu 1.The subject of the present invention is a multi-compartment capsule-in-capsule system for the encapsulation of peptides based on a hyaluronic acid derivative, the stabilization of which does not require the use of surfactants, emulsifiers and / or stabilizers, acting as a carrier, which solves the problem of protecting sensitive hydrophilic substances against aggressive external environment, including degradation and inactivation, but not limited to proteins, and allows the simultaneous administration of active substances of different hydrophilicity. The invention also relates to a method for preparing a multi-compartment "capsule-in-capsule" system in the form of a water-oil-water double emulsion and the use of the multi-compartment for the treatment of type 1 diabetes.
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL430624A PL430624A1 (en) | 2019-07-16 | 2019-07-16 | Multi-compartment capsule-in-capsule system for encapsulating peptides |
| EP19786403.6A EP3836900A1 (en) | 2018-08-17 | 2019-08-19 | Multicompartment system of nanocapsule-in-nanocapsule type, for encapsulation of a lipophilic and hydrophilic compound, and the related production method |
| US17/268,652 US20210196630A1 (en) | 2018-08-17 | 2019-08-19 | Multicompartment system of nanocapsule-in-nanocapsule type, for encapsulation of a lipophilic and hydrophilic compound, and the related production method |
| PCT/PL2019/000069 WO2020036501A1 (en) | 2018-08-17 | 2019-08-19 | Multicompartment system of nanocapsule-in-nanocapsule type, for encapsulation of a lipophilic and hydrophilic compound, and the related production method |
| JP2021532256A JP7465876B2 (en) | 2018-08-17 | 2019-08-19 | Multicompartment systems of nanocapsule-in-nanocapsule type for the encapsulation of lipophilic and hydrophilic compounds and related manufacturing methods |
| AU2019322781A AU2019322781A1 (en) | 2018-08-17 | 2019-08-19 | Multicompartment system of nanocapsule-in-nanocapsule type, for encapsulation of a lipophilic and hydrophilic compound, and the related production method |
| CA3109154A CA3109154A1 (en) | 2018-08-17 | 2019-08-19 | Multicompartment system of nanocapsule-in-nanocapsule type, for encapsulation of a lipophilic and hydrophilic compound, and the related production method |
| CN201980067275.8A CN112888428A (en) | 2018-08-17 | 2019-08-19 | Nanocoapsular nanocapsule-in-nanocapsule type multicompartment system encapsulating lipophilic and hydrophilic compounds and related production method |
| MX2021001824A MX2021001824A (en) | 2018-08-17 | 2019-08-19 | Multicompartment system of nanocapsule-in-nanocapsule type, for encapsulation of a lipophilic and hydrophilic compound, and the related production method. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL430624A PL430624A1 (en) | 2019-07-16 | 2019-07-16 | Multi-compartment capsule-in-capsule system for encapsulating peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL430624A1 true PL430624A1 (en) | 2021-01-25 |
Family
ID=74222247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL430624A PL430624A1 (en) | 2018-08-17 | 2019-07-16 | Multi-compartment capsule-in-capsule system for encapsulating peptides |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL430624A1 (en) |
-
2019
- 2019-07-16 PL PL430624A patent/PL430624A1/en unknown
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