PL413949A1 - Method for producing optically pure (+)-(R)-7-hydroxyflavanone - Google Patents
Method for producing optically pure (+)-(R)-7-hydroxyflavanoneInfo
- Publication number
- PL413949A1 PL413949A1 PL413949A PL41394915A PL413949A1 PL 413949 A1 PL413949 A1 PL 413949A1 PL 413949 A PL413949 A PL 413949A PL 41394915 A PL41394915 A PL 41394915A PL 413949 A1 PL413949 A1 PL 413949A1
- Authority
- PL
- Poland
- Prior art keywords
- hydroxyflavanone
- optically pure
- producing optically
- hours
- organic solvent
- Prior art date
Links
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Sposób wytwarzania (+)-(R)-7-hydroksyflawanonu o wzorze 2, polega na tym, że do podłoża odpowiedniego dla grzybów strzępkowych wprowadza się szczep Aspergillus niger KB, następnie po upływie co najmniej 48 godzin do hodowli wprowadza się substrat, którym jest (±)-octan 7-hydroksyflawanonu o wzorze 1, rozpuszczony w rozpuszczalniku organicznym mieszającym się z wodą, transformację prowadzi się przy ciągłym wstrząsaniu, co najwyżej 30 godzin, po czym produkt ekstrahuje się rozpuszczalnikiem organicznym niemieszającym się z wodą i oczyszcza chromatograficznie. Związek ten może znaleźć zastosowanie jako antyoksydant w przemyśle spożywczym oraz jako składnik preparatów farmaceutycznych i kosmetycznych.The method of producing (+) - (R) -7-hydroxyflavanone of the formula II consists in the introduction of Aspergillus niger KB strain into a medium suitable for filamentous fungi, then after at least 48 hours the substrate which is 7-hydroxyflavanone (±) -acetate 1, dissolved in a water-miscible organic solvent, transformation is carried out with continuous shaking, at most 30 hours, after which the product is extracted with a water-immiscible organic solvent and purified by chromatography. This compound can be used as an antioxidant in the food industry and as an ingredient in pharmaceutical and cosmetic preparations.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL41394915A PL233418B1 (en) | 2015-09-14 | 2015-09-14 | Method for producing optically pure (+)-(R)-7-hydroxyflavanone |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL41394915A PL233418B1 (en) | 2015-09-14 | 2015-09-14 | Method for producing optically pure (+)-(R)-7-hydroxyflavanone |
Publications (2)
Publication Number | Publication Date |
---|---|
PL413949A1 true PL413949A1 (en) | 2017-03-27 |
PL233418B1 PL233418B1 (en) | 2019-10-31 |
Family
ID=58360235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL41394915A PL233418B1 (en) | 2015-09-14 | 2015-09-14 | Method for producing optically pure (+)-(R)-7-hydroxyflavanone |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL233418B1 (en) |
-
2015
- 2015-09-14 PL PL41394915A patent/PL233418B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL233418B1 (en) | 2019-10-31 |
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