PL382907A1 - Sposób otrzymywania meloxicamu o wysokiej czystości oraz soli potasowej meloxicamu - Google Patents

Sposób otrzymywania meloxicamu o wysokiej czystości oraz soli potasowej meloxicamu

Info

Publication number: PL382907A1
Authority: PL; Poland
Prior art keywords: meloxicam; obtaining; high purity; potassium; sole
Prior art date: 2004-12-18

Application number

PL382907A

Other languages

English (en)

Inventor

Tibor Mezei

Gyula Simig

Eniko Molnar

Gyula Lukacs

Marta Porcs-Makkay

Balazs Volk

Fekete Valeria Hofmanne

Kálmán Nagy

Norbert Mesterhazy

Gyorgy Krasznai

Donath Gyorgyi Vereczkeyne

Gyulane Kortvelyessy

Eva Pecsi

Original Assignee

Egis Gyogyszergyar Nyrt.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-12-18

Filing date

2005-12-16

Publication date

2008-02-04

2005-12-16 Application filed by Egis Gyogyszergyar Nyrt. filed Critical Egis Gyogyszergyar Nyrt.

2008-02-04 Publication of PL382907A1 publication Critical patent/PL382907A1/pl

Links

ZRVUJXDFFKFLMG-UHFFFAOYSA-N Meloxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=NC=C(C)S1 ZRVUJXDFFKFLMG-UHFFFAOYSA-N 0.000 title abstract 6
229960001929 meloxicam Drugs 0.000 title abstract 6
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 title 1
229910052700 potassium Inorganic materials 0.000 title 1
239000011591 potassium Substances 0.000 title 1
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
150000007522 mineralic acids Chemical class 0.000 abstract 1
150000007524 organic acids Chemical class 0.000 abstract 1
229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
LTUDISCZKZHRMJ-UHFFFAOYSA-N potassium;hydrate Chemical compound O.[K] LTUDISCZKZHRMJ-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Cosmetics (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL382907A 2004-12-18 2005-12-16 Sposób otrzymywania meloxicamu o wysokiej czystości oraz soli potasowej meloxicamu PL382907A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU0402634A HU227359B1 (en)	2004-12-18	2004-12-18	Process for producing meloxicam and meloxicam potassium salt of high purity

Publications (1)

Publication Number	Publication Date
PL382907A1 true PL382907A1 (pl)	2008-02-04

Family

ID=89985699

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL382907A PL382907A1 (pl)	2004-12-18	2005-12-16	Sposób otrzymywania meloxicamu o wysokiej czystości oraz soli potasowej meloxicamu
PL05823064T PL1828178T3 (pl)	2004-12-18	2005-12-16	Sposób wytwarzania Meloksykamu o dużej czystości i soli potasowej Meloksykamu

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL05823064T PL1828178T3 (pl)	2004-12-18	2005-12-16	Sposób wytwarzania Meloksykamu o dużej czystości i soli potasowej Meloksykamu

Country Status (23)

Country	Link
US (2)	US8097616B2 (pl)
EP (1)	EP1828178B1 (pl)
JP (1)	JP5329812B2 (pl)
CN (1)	CN101090900B (pl)
AT (1)	ATE486867T1 (pl)
BG (1)	BG66118B1 (pl)
CY (1)	CY1112714T1 (pl)
CZ (1)	CZ2007465A3 (pl)
DE (1)	DE602005024612D1 (pl)
DK (1)	DK1828178T3 (pl)
EA (1)	EA013791B1 (pl)
ES (1)	ES2356840T3 (pl)
HK (1)	HK1114848A1 (pl)
HU (1)	HU227359B1 (pl)
IL (1)	IL183739A (pl)
NO (1)	NO20073602L (pl)
PL (2)	PL382907A1 (pl)
PT (1)	PT1828178E (pl)
RU (1)	RU2394032C2 (pl)
SI (1)	SI1828178T1 (pl)
SK (1)	SK50932007A3 (pl)
UA (1)	UA89657C2 (pl)
WO (1)	WO2006064298A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2443891B (en) *	2006-11-20	2009-04-08	Norbrook Lab Ltd	Process for the purification of meloxicam
US8637449B2 (en) *	2009-08-27	2014-01-28	Merck Sharp & Dohme Corp.	Processes for preparing protease inhibitors of hepatitis C virus
RU2465892C1 (ru) *	2011-09-21	2012-11-10	Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет (НГУ)"	Способ получения высокодисперсного мелоксикама
CN103772378B (zh) *	2014-01-26	2016-02-24	悦康药业集团有限公司	一种美洛昔康化合物及其片剂
CN106896162B (zh) *	2015-12-17	2019-10-18	瑞普（天津）生物药业有限公司	一种检测美洛昔康片中杂质的hplc方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2756113A1 (de) *	1977-12-16	1979-06-21	Thomae Gmbh Dr K	Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0945134A1 (de)	1998-03-27	1999-09-29	Boehringer Ingelheim Pharma KG	Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
ES2223209B1 (es)	2001-12-11	2005-10-01	Esteve Quimica, S.A.	Nuevas formas cristalinas del meloxicam y procedimientos para su preparacion e interconversion.
US8992980B2 (en)	2002-10-25	2015-03-31	Boehringer Ingelheim Vetmedica Gmbh	Water-soluble meloxicam granules
ITMI20041918A1 (it)	2004-10-11	2005-01-11	A M S A Anonima Materie Sintetiche Affini Spa	Processo di purificazione di meloxicam

2004
- 2004-12-18 HU HU0402634A patent/HU227359B1/hu not_active IP Right Cessation
2005
- 2005-12-16 DE DE602005024612T patent/DE602005024612D1/de active Active
- 2005-12-16 JP JP2007546204A patent/JP5329812B2/ja not_active Expired - Fee Related
- 2005-12-16 EA EA200701256A patent/EA013791B1/ru not_active IP Right Cessation
- 2005-12-16 CN CN2005800434052A patent/CN101090900B/zh not_active Expired - Fee Related
- 2005-12-16 CZ CZ20070465A patent/CZ2007465A3/cs unknown
- 2005-12-16 US US11/793,548 patent/US8097616B2/en not_active Expired - Fee Related
- 2005-12-16 RU RU2007126723/04A patent/RU2394032C2/ru not_active IP Right Cessation
- 2005-12-16 AT AT05823064T patent/ATE486867T1/de active
- 2005-12-16 PL PL382907A patent/PL382907A1/pl not_active Application Discontinuation
- 2005-12-16 DK DK05823064.0T patent/DK1828178T3/da active
- 2005-12-16 PL PL05823064T patent/PL1828178T3/pl unknown
- 2005-12-16 UA UAA200708233A patent/UA89657C2/ru unknown
- 2005-12-16 WO PCT/HU2005/000136 patent/WO2006064298A1/en active Application Filing
- 2005-12-16 PT PT05823064T patent/PT1828178E/pt unknown
- 2005-12-16 ES ES05823064T patent/ES2356840T3/es active Active
- 2005-12-16 SI SI200531217T patent/SI1828178T1/sl unknown
- 2005-12-16 SK SK5093-2007A patent/SK50932007A3/sk not_active Application Discontinuation
- 2005-12-16 EP EP05823064A patent/EP1828178B1/en active Active
2007
- 2007-06-07 IL IL183739A patent/IL183739A/en not_active IP Right Cessation
- 2007-07-12 NO NO20073602A patent/NO20073602L/no unknown
- 2007-07-18 BG BG109916A patent/BG66118B1/bg unknown
2008
- 2008-05-02 HK HK08104873.6A patent/HK1114848A1/xx not_active IP Right Cessation
2011
- 2011-01-28 CY CY20111100084T patent/CY1112714T1/el unknown
- 2011-10-12 US US13/271,445 patent/US20120035162A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EA013791B1 (ru)	2010-06-30
US8097616B2 (en)	2012-01-17
DK1828178T3 (da)	2011-02-14
US20120035162A1 (en)	2012-02-09
DE602005024612D1 (de)	2010-12-16
RU2007126723A (ru)	2009-01-27
PL1828178T3 (pl)	2011-07-29
ES2356840T3 (es)	2011-04-13
UA89657C2 (ru)	2010-02-25
SI1828178T1 (sl)	2011-03-31
HU227359B1 (en)	2011-04-28
JP2008524197A (ja)	2008-07-10
JP5329812B2 (ja)	2013-10-30
EP1828178B1 (en)	2010-11-03
CY1112714T1 (el)	2016-02-10
EA200701256A1 (ru)	2007-12-28
EP1828178A1 (en)	2007-09-05
BG66118B1 (bg)	2011-05-31
RU2394032C2 (ru)	2010-07-10
SK50932007A3 (sk)	2008-03-05
CN101090900A (zh)	2007-12-19
WO2006064298A1 (en)	2006-06-22
IL183739A (en)	2011-12-29
IL183739A0 (en)	2007-09-20
PT1828178E (pt)	2011-02-07
ATE486867T1 (de)	2010-11-15
HUP0402634A2 (en)	2006-11-28
HU0402634D0 (en)	2005-02-28
HUP0402634A3 (en)	2008-10-28
BG109916A (bg)	2008-02-29
NO20073602L (no)	2007-09-14
HK1114848A1 (en)	2008-11-14
US20090215757A1 (en)	2009-08-27
CZ2007465A3 (cs)	2007-12-05
CN101090900B (zh)	2013-11-20

Legal Events

Date	Code	Title	Description
2013-04-30	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

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