PL348916A1 - Utilisation of 2-substituted 1,2-benzisothiazole derivatives and 3-substituted tetrahydropyridopyrimidinone derivatives for the prophylaxis and therapy of cerebral ischaemia - Google Patents
Utilisation of 2-substituted 1,2-benzisothiazole derivatives and 3-substituted tetrahydropyridopyrimidinone derivatives for the prophylaxis and therapy of cerebral ischaemiaInfo
- Publication number
- PL348916A1 PL348916A1 PL99348916A PL34891699A PL348916A1 PL 348916 A1 PL348916 A1 PL 348916A1 PL 99348916 A PL99348916 A PL 99348916A PL 34891699 A PL34891699 A PL 34891699A PL 348916 A1 PL348916 A1 PL 348916A1
- Authority
- PL
- Poland
- Prior art keywords
- substituted
- derivatives
- utilisation
- prophylaxis
- therapy
- Prior art date
Links
- -1 2-substituted 1,2-benzisothiazole Chemical class 0.000 title 2
- 206010008120 Cerebral ischaemia Diseases 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19900544A DE19900544A1 (de) | 1999-01-11 | 1999-01-11 | Verwendung von Verbindungen der Formel I zur Prophylaxe und Therapie der zerebralen Ischämie |
PCT/EP1999/010275 WO2000041697A1 (fr) | 1999-01-11 | 1999-12-22 | Utilisation de derives de 1,2-benzisothiazol 2-substitues et de derives de tetrahydropyridopyrimidinone 3-substitues pour assurer la prophylaxie et le traitement de l'ischemie cerebrale |
Publications (1)
Publication Number | Publication Date |
---|---|
PL348916A1 true PL348916A1 (en) | 2002-06-17 |
Family
ID=7893835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL99348916A PL348916A1 (en) | 1999-01-11 | 1999-12-22 | Utilisation of 2-substituted 1,2-benzisothiazole derivatives and 3-substituted tetrahydropyridopyrimidinone derivatives for the prophylaxis and therapy of cerebral ischaemia |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1140099A1 (fr) |
JP (1) | JP2002534467A (fr) |
KR (1) | KR20010101440A (fr) |
CN (1) | CN1333685A (fr) |
AR (1) | AR029741A1 (fr) |
AU (1) | AU2285100A (fr) |
BG (1) | BG105688A (fr) |
BR (1) | BR9916888A (fr) |
CA (1) | CA2359390A1 (fr) |
DE (1) | DE19900544A1 (fr) |
HU (1) | HUP0200520A3 (fr) |
IL (1) | IL144145A0 (fr) |
MX (1) | MXPA01006966A (fr) |
NO (1) | NO20013408L (fr) |
PL (1) | PL348916A1 (fr) |
SK (1) | SK9682001A3 (fr) |
TR (1) | TR200102009T2 (fr) |
WO (1) | WO2000041697A1 (fr) |
ZA (1) | ZA200105473B (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4654035B2 (ja) | 2002-11-05 | 2011-03-16 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 抗菌剤 |
EP1667979A4 (fr) * | 2003-09-23 | 2007-04-18 | Merck & Co Inc | Inhibiteurs des canaux potassiques a l'isoquinoleine |
CN101296914B (zh) * | 2005-08-26 | 2012-07-18 | 盐野义制药株式会社 | 具有ppar激动活性的衍生物 |
CN101801939A (zh) * | 2007-09-20 | 2010-08-11 | 科泰克斯药品公司 | 用于增强谷氨酸能突触反应的3-取代1,2,3-三嗪-4-酮类和3-取代1,3-嘧啶酮类 |
MA41168A (fr) | 2014-12-17 | 2017-10-24 | Acraf | Nouveaux composés antibactériens |
CN108484594B (zh) * | 2018-02-09 | 2020-08-04 | 福建医科大学 | 一种烷氧基取代四氢吡啶并嘧啶类化合物或其可用盐及其制备方法与应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3620643A1 (de) * | 1985-06-22 | 1987-01-22 | Sandoz Ag | Thiazole, ihre herstellung und verwendung |
DE3831888A1 (de) * | 1988-09-20 | 1990-03-29 | Troponwerke Gmbh & Co Kg | Arzneimittel zur behandlung von apoplexia cerebri |
JP3036789B2 (ja) * | 1990-06-22 | 2000-04-24 | 三井化学株式会社 | 新規な複素環式化合物及び医薬組成物 |
DE19746612A1 (de) * | 1997-10-22 | 1999-04-29 | Basf Ag | 2-Substituierte 1,2-Benzisothiazol-Derivate, ihre Herstellung und Verwendung |
DE19747063A1 (de) * | 1997-10-24 | 1999-04-29 | Basf Ag | 3-substituierte Tetrahydropyridopyrimidinon-Derivate, ihre Herstellung und Verwendung |
-
1999
- 1999-01-11 DE DE19900544A patent/DE19900544A1/de not_active Withdrawn
- 1999-12-22 BR BR9916888-0A patent/BR9916888A/pt not_active IP Right Cessation
- 1999-12-22 CA CA002359390A patent/CA2359390A1/fr not_active Abandoned
- 1999-12-22 WO PCT/EP1999/010275 patent/WO2000041697A1/fr not_active Application Discontinuation
- 1999-12-22 JP JP2000593308A patent/JP2002534467A/ja active Pending
- 1999-12-22 CN CN99815452A patent/CN1333685A/zh active Pending
- 1999-12-22 MX MXPA01006966A patent/MXPA01006966A/es unknown
- 1999-12-22 EP EP99966990A patent/EP1140099A1/fr not_active Withdrawn
- 1999-12-22 SK SK968-2001A patent/SK9682001A3/sk unknown
- 1999-12-22 KR KR1020017008690A patent/KR20010101440A/ko not_active Application Discontinuation
- 1999-12-22 HU HU0200520A patent/HUP0200520A3/hu unknown
- 1999-12-22 TR TR2001/02009T patent/TR200102009T2/xx unknown
- 1999-12-22 IL IL14414599A patent/IL144145A0/xx unknown
- 1999-12-22 PL PL99348916A patent/PL348916A1/xx not_active Application Discontinuation
- 1999-12-22 AU AU22851/00A patent/AU2285100A/en not_active Abandoned
-
2000
- 2000-01-06 AR ARP000100036A patent/AR029741A1/es unknown
-
2001
- 2001-07-03 ZA ZA200105473A patent/ZA200105473B/xx unknown
- 2001-07-10 BG BG105688A patent/BG105688A/xx unknown
- 2001-07-10 NO NO20013408A patent/NO20013408L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TR200102009T2 (tr) | 2002-01-21 |
AR029741A1 (es) | 2003-07-16 |
MXPA01006966A (es) | 2002-04-10 |
CN1333685A (zh) | 2002-01-30 |
KR20010101440A (ko) | 2001-11-14 |
HUP0200520A3 (en) | 2003-04-28 |
BR9916888A (pt) | 2001-11-20 |
CA2359390A1 (fr) | 2000-07-20 |
BG105688A (en) | 2002-02-28 |
EP1140099A1 (fr) | 2001-10-10 |
AU2285100A (en) | 2000-08-01 |
NO20013408L (no) | 2001-08-21 |
WO2000041697A1 (fr) | 2000-07-20 |
NO20013408D0 (no) | 2001-07-10 |
IL144145A0 (en) | 2002-05-23 |
SK9682001A3 (en) | 2002-03-05 |
ZA200105473B (en) | 2002-10-03 |
HUP0200520A2 (hu) | 2002-07-29 |
JP2002534467A (ja) | 2002-10-15 |
DE19900544A1 (de) | 2000-07-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1044537A1 (en) | 1,4-benzothiazepine derivatives methods for the production thereof, medicaments containing these compounds and the use | |
IL143979A0 (en) | Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression | |
HK1051695A1 (en) | N6 heterocyclic 8-modified andenosine derivatives. | |
HUP0203225A3 (en) | Benzodiazepin derivatives, the production and use thereof | |
PL347885A1 (en) | Azepinoindole derivatives, the production and use thereof | |
HK1047284A1 (en) | 2-amino-benzoxazinone derivatives for the treatment of obesity | |
HUP0202477A3 (en) | Use of phthalazine derivatives | |
IL139491A0 (en) | Phthalazine derivatives as phosphodiesterase-4 inhibitors | |
ZA200107689B (en) | 1-Arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives for the treatment of CNS disorders. | |
AU2001279709A1 (en) | Pyrimidine derivatives and their use for preventing and treating cerebral ischaemia | |
AU4694999A (en) | Use of thiazolidinedione derivatives for the treatment or prevention of cataracts | |
HUP0203611A3 (en) | 14,15-beta-methylene substituted androgens and their use for preparation of the medicaments | |
GB2346147B (en) | Stabilized metallocene polyolefins | |
PL343728A1 (en) | Carbapenem derivatives, utilization thereof and intermediate compounds of the same | |
PL348916A1 (en) | Utilisation of 2-substituted 1,2-benzisothiazole derivatives and 3-substituted tetrahydropyridopyrimidinone derivatives for the prophylaxis and therapy of cerebral ischaemia | |
AU1028501A (en) | Isoquinoline and quinazoline derivatives for the treatment of cns disorders | |
HK1059782A1 (en) | Indole derivatives useful for the treatment of cnsdisorders | |
HUP0001891A3 (en) | Medicament for the treatment of migraine | |
SG82014A1 (en) | The use of aryl-cyclohexylamine derivatives against cns disorders | |
HU9900123D0 (en) | 1-isothiazolidinone derivatives of azetidine-2-one, processes for the preparation thereof and use thereof | |
AU2504101A (en) | Device for carrying out the oscillation-induced selective treatment of malignantdiseases | |
GB9926985D0 (en) | Use of substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides for the treatment of diseases | |
HK1042039A1 (en) | Use of phanquinone for the treatment or preventionof memory impairment. | |
IL157127A0 (en) | Indoline derivatives and processes for the preparation thereof | |
SI1068184T1 (en) | N-aryloxyethylamine derivatives for the treatment of depression |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |