PL3453721T3 - Process of manufacture of annexin v - Google Patents
Process of manufacture of annexin vInfo
- Publication number
- PL3453721T3 PL3453721T3 PL18182321.2T PL18182321T PL3453721T3 PL 3453721 T3 PL3453721 T3 PL 3453721T3 PL 18182321 T PL18182321 T PL 18182321T PL 3453721 T3 PL3453721 T3 PL 3453721T3
- Authority
- PL
- Poland
- Prior art keywords
- annexin
- manufacture
- Prior art date
Links
- 102000000412 Annexin Human genes 0.000 title 1
- 108050008874 Annexin Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Analytical Chemistry (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1516516.0A GB2542391A (en) | 2015-09-17 | 2015-09-17 | Process of manufacture |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3453721T3 true PL3453721T3 (en) | 2022-11-07 |
Family
ID=54544424
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL18182321.2T PL3453721T3 (en) | 2015-09-17 | 2016-09-16 | Process of manufacture of annexin v |
PL16766559T PL3283506T3 (en) | 2015-09-17 | 2016-09-16 | Process of manufacture of annexin v |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL16766559T PL3283506T3 (en) | 2015-09-17 | 2016-09-16 | Process of manufacture of annexin v |
Country Status (11)
Country | Link |
---|---|
US (3) | US11773134B2 (en) |
EP (3) | EP4134376A1 (en) |
JP (4) | JP6689371B2 (en) |
CN (3) | CN116333087A (en) |
CA (2) | CA3193026A1 (en) |
DK (2) | DK3283506T3 (en) |
ES (2) | ES2699155T3 (en) |
GB (1) | GB2542391A (en) |
HK (1) | HK1251580B (en) |
PL (2) | PL3453721T3 (en) |
WO (1) | WO2017046391A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3495376A1 (en) * | 2017-12-05 | 2019-06-12 | ChromaCon AG | Improved chromatographic process for cell culture harvest |
EP3560945A1 (en) * | 2018-04-27 | 2019-10-30 | F. Hoffmann-La Roche AG | Methods for purification of polypeptides using polysorbates |
EP3845548A4 (en) * | 2018-08-31 | 2022-05-25 | Kaneka Corporation | Method for purifying antibody or antibody-like molecule |
CN110669141A (en) * | 2019-09-29 | 2020-01-10 | 杭州联科生物技术股份有限公司 | Allophycocyanin (APC) and Annexin V protein coupling method |
TW202146042A (en) * | 2020-03-06 | 2021-12-16 | 瑞典商阿斯特捷利康公司 | Synergistic and targeting compositions for treatment of arterial and venous thrombosis |
CN111378005B (en) * | 2020-04-03 | 2021-08-17 | 安徽环球基因科技有限公司 | Adjustable protein purifying device |
AR127912A1 (en) * | 2021-12-08 | 2024-03-06 | Ferring Bv | PROTEIN PURIFICATION METHOD BY PRECIPITATION |
CN114539383B (en) * | 2022-02-24 | 2024-03-26 | 南京大学 | Preparation method and application of crystal structure of human annexin A5 mutant dimer |
GB202207263D0 (en) * | 2022-05-18 | 2022-06-29 | Annexin Pharmaceuticals Ab | Therapeutic compositions |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT40695A (en) | 1985-01-10 | 1987-01-28 | Biogen Nv | Dna sequences, recombinant dna molecules and processes for preparing humane lipocortine like polypeptides |
DE3643182A1 (en) * | 1986-12-18 | 1988-06-30 | Behringwerke Ag | MEDICINAL PRODUCTS CONTAINING THE TISSUE PROTEIN PP4, METHOD FOR THE PRODUCTION OF PP4 AND ITS PASTEURIZATION AND THE USE OF PP4 |
DE3939169A1 (en) * | 1989-11-27 | 1991-05-29 | Behringwerke Ag | METHOD FOR PURIFYING LIPOCORTINES |
DE4003773A1 (en) * | 1990-02-08 | 1991-08-14 | Behringwerke Ag | METHOD FOR PURIFYING LIPOCORTINES |
DE4012341A1 (en) * | 1990-04-18 | 1991-10-24 | Behringwerke Ag | MONOCLONAL ANTIBODY AGAINST PP4, PROCESS FOR THEIR PREPARATION AND ITS USE |
US5968477A (en) * | 1994-01-24 | 1999-10-19 | Neorx Corporation | Radiolabeled annexin conjugates with hexose and a chelator |
JP2000239299A (en) | 1999-02-15 | 2000-09-05 | Snow Brand Milk Prod Co Ltd | New protein and its production |
US6492327B2 (en) * | 2000-12-19 | 2002-12-10 | Sulzer Biologics Inc. | Isolation of purified TGF- β1 and TGF -β2 from bone tissue |
GB0101300D0 (en) * | 2001-01-18 | 2001-02-28 | Univ Cambridge Tech | Primordial germ cell genes |
JP2004528025A (en) * | 2001-02-21 | 2004-09-16 | サーロメッド・インコーポレーテッド | Modified annexin proteins and methods for preventing thrombosis |
US7635680B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaceuticals, Inc. | Attenuation of reperfusion injury |
US7645739B2 (en) | 2001-02-21 | 2010-01-12 | Alavita Pharmaceuticals, Inc. | Modified annexin compositions and methods of using same |
US20020197261A1 (en) * | 2001-04-26 | 2002-12-26 | Chun Li | Therapeutic agent/ligand conjugate compositions, their methods of synthesis and use |
US6825027B2 (en) * | 2001-12-10 | 2004-11-30 | Baxter Healthcare S.A. | Method of production of purified hepatitis a virus particles and vaccine preparation |
CH696701A5 (en) * | 2001-12-18 | 2007-10-15 | Hoffmann La Roche | A method for testing an agent for its ability to inhibit heparanase activity. |
US7148049B2 (en) * | 2002-04-02 | 2006-12-12 | Roche Molecular Systems, Inc. | Thermostable or thermoactive DNA polymerase molecules with attenuated 3′-5′ exonuclease activity |
TW200504218A (en) | 2003-03-04 | 2005-02-01 | Smithkline Beecham Corp | Methods for preventing gluconoylation of proteins |
CA2559167A1 (en) | 2004-03-11 | 2005-09-22 | Alavita, Inc. | Modified annexin proteins and methods for preventing thrombosis |
PL1755642T3 (en) * | 2004-04-15 | 2010-06-30 | Athera Biotechnologies Ab | Annexin v for preventing plaque rupture |
CA2573259A1 (en) * | 2004-07-06 | 2006-02-09 | Bioren Inc. | High affinity anti-tnf-alpha antibodies and method |
US7511016B2 (en) * | 2004-07-07 | 2009-03-31 | Mosamedix B.V. | Annexins, derivatives thereof, and annexin-cys variants, as well as therapeutic and diagnostic uses thereof |
WO2006081320A2 (en) * | 2005-01-27 | 2006-08-03 | Human Genome Sciences, Inc. | Pharmaceutical formulation |
CA2708956C (en) * | 2007-12-18 | 2018-07-17 | Athera Biotechnologies Ab | Use of annexin a5 for the treatment of vascular disease |
GB0905348D0 (en) | 2009-03-27 | 2009-05-13 | Ucl Business Plc | Carrier |
EP3216457B1 (en) * | 2008-02-22 | 2019-04-10 | Annexin Pharmaceuticals AB | Compounds and methods for the prevention or treatment of restenosis |
ITCZ20080004A1 (en) * | 2008-02-26 | 2009-08-27 | Univ Bari | MONOSPECIFIC ANTIBODY AND PRODUCTION METHOD BY USING AS AN ANTIGEN OF AN ISOFORM OF THE HUMAN FAD SINTETASIS |
WO2010043045A1 (en) | 2008-10-17 | 2010-04-22 | London Health Sciences Centre Research Inc. | Annexin and its use to treat inflammatory disorders |
EP2381958A1 (en) * | 2008-10-17 | 2011-11-02 | Tallinn University Of Technology | Potato virus a coat protein-based vaccine for treating melanoma and its use |
EP3998479A1 (en) * | 2008-12-19 | 2022-05-18 | Medirista Biotechnologies AB | Oxidized cardiolipin as a novel pro-inflammatory factor |
NZ596862A (en) * | 2009-06-03 | 2013-07-26 | Mosamedix Bv | Method for enhancing phagocytosis of phosphatidylserine-exposing cells by using annexin variants with added rgd sequences |
US20120219538A1 (en) * | 2009-11-02 | 2012-08-30 | Therapeomic Ag | Stabilized protein formulations and use thereof |
KR101780518B1 (en) * | 2010-04-29 | 2017-09-21 | 박스알타 인코퍼레이티드 | Purification method for divalent cation binding proteins on anion exchange resin |
US8691771B2 (en) * | 2010-05-21 | 2014-04-08 | Merrimack Pharmaceuticals, Inc. | Bi-specific fusion proteins for tissue repair |
CN102690345B (en) | 2011-03-24 | 2014-03-19 | 江苏靶标生物医药研究所有限公司 | Human annexin V variant and its expression, preparation method and use |
EP2694538B1 (en) * | 2011-04-05 | 2016-09-14 | Annexin Pharmaceuticals AB | Therapeutic and prophylactic methods, uses and compositions comprising anexin a5 |
US9701710B2 (en) * | 2011-10-14 | 2017-07-11 | Baxalta Incorporated | Protein purification by anion exchange chromatography |
EP2850201A4 (en) | 2012-05-11 | 2016-08-31 | Alexander Krantz | Site-specific labeling and targeted delivery of proteins for the treatment of cancer |
KR101762047B1 (en) * | 2012-11-05 | 2017-07-27 | 화이자 인코포레이티드 | Spliceostatin analogs |
MX367748B (en) * | 2012-12-21 | 2019-09-04 | Glenmark Pharmaceuticals Sa | Anti her2 antibody formulation. |
US10799579B2 (en) * | 2015-01-16 | 2020-10-13 | The Johns Hopkins University | Methods for enhancing antigen-specific immune responses |
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