PL3441107T3 - Mikroigła wykorzystująca bioabsorbowalny metal - Google Patents

Mikroigła wykorzystująca bioabsorbowalny metal

Info

Publication number
PL3441107T3
PL3441107T3 PL17779369T PL17779369T PL3441107T3 PL 3441107 T3 PL3441107 T3 PL 3441107T3 PL 17779369 T PL17779369 T PL 17779369T PL 17779369 T PL17779369 T PL 17779369T PL 3441107 T3 PL3441107 T3 PL 3441107T3
Authority
PL
Poland
Prior art keywords
microneedle
bioabsorbable metal
bioabsorbable
metal
Prior art date
Application number
PL17779369T
Other languages
English (en)
Inventor
Sung Youn Cho
Jong Tack Kim
Hyun Wook Choo
Original Assignee
Labnpeople Co.,Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labnpeople Co.,Ltd. filed Critical Labnpeople Co.,Ltd.
Priority claimed from PCT/KR2017/003775 external-priority patent/WO2017176069A2/ko
Publication of PL3441107T3 publication Critical patent/PL3441107T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/022Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • A61L2300/604Biodegradation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
PL17779369T 2016-04-07 2017-04-06 Mikroigła wykorzystująca bioabsorbowalny metal PL3441107T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20160042690 2016-04-07
KR1020160181865A KR101879851B1 (ko) 2016-04-07 2016-12-29 생체흡수성 금속을 이용한 마이크로 니들
EP17779369.2A EP3441107B1 (en) 2016-04-07 2017-04-06 Microneedle using bioabsorbable metal
PCT/KR2017/003775 WO2017176069A2 (ko) 2016-04-07 2017-04-06 생체흡수성 금속을 이용한 마이크로 니들

Publications (1)

Publication Number Publication Date
PL3441107T3 true PL3441107T3 (pl) 2021-08-02

Family

ID=60297749

Family Applications (2)

Application Number Title Priority Date Filing Date
PL17779369T PL3441107T3 (pl) 2016-04-07 2017-04-06 Mikroigła wykorzystująca bioabsorbowalny metal
PL17779377.5T PL3444003T3 (pl) 2016-04-07 2017-04-07 Mikroigła z zastosowaniem biodegradowalnego metalu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL17779377.5T PL3444003T3 (pl) 2016-04-07 2017-04-07 Mikroigła z zastosowaniem biodegradowalnego metalu

Country Status (9)

Country Link
US (2) US20190151638A1 (pl)
EP (2) EP3441107B1 (pl)
JP (2) JP6995830B2 (pl)
KR (5) KR20170115429A (pl)
CN (2) CN109069812B (pl)
BR (1) BR112018070666A2 (pl)
ES (2) ES2863905T3 (pl)
MX (2) MX2018012334A (pl)
PL (2) PL3441107T3 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170115429A (ko) * 2016-04-07 2017-10-17 랩앤피플주식회사 생체분해성 금속을 이용한 마이크로 니들
EP3493872A4 (en) * 2016-08-03 2020-04-08 Verndari, Inc. MICROARRAYS AND METHOD
KR102119675B1 (ko) * 2017-12-11 2020-06-05 랩앤피플주식회사 고밀도 마이크로 니들
KR102022968B1 (ko) * 2018-01-12 2019-09-19 주식회사 에스엔비아 마이크로 니들 시트 구조 및 그 제조방법
KR102094744B1 (ko) * 2018-01-26 2020-03-30 가천대학교 산학협력단 마이크로 니들 및 이의 제조방법
KR102291392B1 (ko) * 2018-03-30 2021-08-20 랩앤피플주식회사 멀티형 마이크로 니들
WO2019190267A1 (ko) * 2018-03-30 2019-10-03 랩앤피플주식회사 멀티형 마이크로 니들
WO2019225948A1 (ko) 2018-05-21 2019-11-28 랩앤피플주식회사 여드름 완화 및 예방용 패치
KR102310566B1 (ko) * 2018-05-21 2021-10-08 랩앤피플주식회사 여드름 완화 및 예방용 패치
KR102114474B1 (ko) * 2018-06-26 2020-05-22 랩앤피플주식회사 백신 접종 피하 삽입용 생체흡수성 약물 전달 캡슐
KR102651395B1 (ko) * 2018-07-05 2024-03-26 랩앤피플주식회사 여드름 완화 및 예방용 화장품 조성물
EP3854316B1 (en) * 2018-09-17 2024-04-24 Labnpeople Co.,Ltd. Thread embedding therapy rope and thread embedding therapy needle apparatus comprising same
WO2020060159A1 (ko) * 2018-09-17 2020-03-26 랩앤피플주식회사 매선요법용 로프 및 이를 포함하는 매선요법용 니들 기구
KR102194089B1 (ko) * 2019-03-18 2020-12-22 랩앤피플주식회사 항산화 활성 및 미백 효과를 갖는 플렉시블 금속 패치 및 그 사용방법
CN111686309A (zh) * 2019-04-09 2020-09-22 珠海天威飞马打印耗材有限公司 一种3d打印皮肤的制备方法
KR102258194B1 (ko) * 2019-08-08 2021-06-02 (주) 반도체로박 침 기구
JP2021040977A (ja) * 2019-09-11 2021-03-18 株式会社ライトニックス 薬物投与デバイス
KR102414580B1 (ko) * 2020-07-17 2022-07-01 한국과학기술연구원 수술 전 감염 방지를 위한 마이크로니들 패치 및 마이크로니들 패치를 이용한 수술 전처리 방법
WO2022098062A1 (ko) * 2020-11-04 2022-05-12 한국재료연구원 고강도 고내식 생분해성 마그네슘 합금 및 이를 이용하는 임플란트
CN112274771B (zh) * 2020-11-26 2022-04-19 南京鼓楼医院 一种仿火箭的微针微马达及其制备方法
KR102593524B1 (ko) * 2021-01-29 2023-10-25 김병준 환경오염 방지 및 야생동물을 보호하기 위한 마스크
KR102565721B1 (ko) * 2021-03-15 2023-08-11 주식회사 비즈엔몰드 피부 약물 주입기용 바늘
WO2023228378A1 (ja) * 2022-05-26 2023-11-30 日本電信電話株式会社 生体組織貼付けパッチ
KR20230172308A (ko) * 2022-06-15 2023-12-22 랩앤피플주식회사 피부 부착성이 우수한 여드름 완화 및 예방용 패치
KR20240039467A (ko) * 2022-09-19 2024-03-26 랩앤피플주식회사 고용량의 약물 전달이 가능한 스탬프형 약물전달장치

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004528900A (ja) * 2001-04-20 2004-09-24 アルザ・コーポレーシヨン 有益な作用物質を含有するコーティングを有する微小突起アレイ
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
AU2003279641B2 (en) * 2002-06-28 2009-06-18 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
CN1863572A (zh) * 2003-08-04 2006-11-15 阿尔扎公司 提高药剂经皮流通量的方法和装置
US8671544B2 (en) * 2004-03-12 2014-03-18 Agency For Science, Technology And Research Methods and moulds for use in fabricating side-ported microneedles
US20060177494A1 (en) 2005-01-31 2006-08-10 Micheal Cormier Coated microprojections having reduced variability and method for producing same
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
US20060258973A1 (en) * 2005-04-27 2006-11-16 Kevin Volt Micro-current Iontophoretic Percutaneous Absorptive Patch
US20080213461A1 (en) * 2005-06-17 2008-09-04 Georgia Tech Research Corporation Coated Microstructures and Methods of Manufacture Thereof
JP2007014588A (ja) 2005-07-08 2007-01-25 Nano Device & System Research Inc 経皮投与装置,経皮投与装置製造用金型
DE102005060203B4 (de) 2005-12-14 2009-11-12 Gkss-Forschungszentrum Geesthacht Gmbh Biokompatibler Magnesiumwerkstoff, Verfahren zu seiner Herstellung und seiner Verwendung
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
WO2008020633A1 (fr) * 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Micro-aiguille et timbre à micro-aiguilles
JP2010503509A (ja) * 2006-09-22 2010-02-04 ユー アンド アイ コーポレーション 生体分解性金属を含むインプラントおよびその製造方法
JPWO2008062832A1 (ja) * 2006-11-22 2010-03-04 凸版印刷株式会社 マイクロニードルアレイ及びマイクロニードルアレイの製造方法
US8778012B2 (en) * 2012-11-27 2014-07-15 Cormatrix Cardiovascular, Inc. ECM constructs for tissue regeneration
JP2008284318A (ja) * 2007-05-15 2008-11-27 Kosumedei Seiyaku Kk 生体由来物質からなる投薬用微細針
JP5034777B2 (ja) * 2007-08-22 2012-09-26 凸版印刷株式会社 針状体の作製方法ならびに製造方法及び針状体
DE102008003453A1 (de) * 2008-01-08 2009-07-09 Robert Bosch Gmbh Verfahren zur Herstellung poröser Mikrostrukturen, nach diesem Verfahren hergestellte poröse Mikrostrukturen sowie deren Verwendung
US20090326447A1 (en) * 2008-06-27 2009-12-31 Joshi Ashok V Transdermal Delivery Apparatus and Method
JP2010069270A (ja) * 2008-09-17 2010-04-02 Yoshiichi Tobinaga 機能剤投与デバイス、その製造方法及び製造装置
US20110014181A1 (en) * 2009-07-20 2011-01-20 Medtronic Vascular, Inc. Microneedle Delivery Device and Methods of Using Same
JP2011083387A (ja) * 2009-10-14 2011-04-28 Kyushu Institute Of Technology 針状体の製造方法並びに針状体および針状体保持シート
KR20110065391A (ko) * 2009-12-07 2011-06-15 유앤아이 주식회사 마그네슘 합금을 이용한 약물 전달체
US20130041330A1 (en) * 2010-02-24 2013-02-14 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device and preparation method
JP2013529507A (ja) * 2010-06-21 2013-07-22 ゾリオン メディカル インコーポレイテッド 生体吸収性インプラント
WO2012116209A1 (en) * 2011-02-23 2012-08-30 Ams Research Corporation Drug releasing pelvic treatment system and method
JP2012217653A (ja) * 2011-04-08 2012-11-12 Asti Corp マイクロニードルとマイクロニードルアレイとマイクロニードルアレイ製造方法
US10624847B2 (en) 2011-08-02 2020-04-21 AnPac BioMedical Science Co., Ltd. Decomposable apparatus and methods for fabricating same
KR102101522B1 (ko) * 2012-06-12 2020-04-16 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들·시트
US9248273B2 (en) * 2012-06-18 2016-02-02 Axion Biosystems, Inc. 3D microelectrode device for live tissue applications
RU2640700C2 (ru) * 2012-06-26 2018-01-11 Биотроник Аг Магниевый сплав, способ его производства и использования
US10246763B2 (en) 2012-08-24 2019-04-02 The Regents Of The University Of California Magnesium-zinc-strontium alloys for medical implants and devices
US9469889B2 (en) 2012-08-31 2016-10-18 DePuy Synthes Products, Inc. Ultrapure magnesium alloy with adjustable degradation rate
US10420921B2 (en) * 2012-09-13 2019-09-24 Avraham Amir Delivery devices and methods for skin augmentation
US11376349B2 (en) 2012-10-05 2022-07-05 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable iron-containing compositions, methods of preparing and applications therefor
US9526884B2 (en) * 2012-11-16 2016-12-27 City University Of Hong Kong Mechanically robust fast-dissolving microneedles for transdermal drug and vaccine delivery
JP6865524B2 (ja) * 2012-12-21 2021-04-28 コリウム, インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
CN202987775U (zh) * 2012-12-27 2013-06-12 浙江诚德包装有限公司 设有易撕线开口的软包装袋
CA2900920C (en) 2013-02-13 2018-08-21 Hisamitsu Pharmaceutical Co., Inc. Microneedle coating composition and microneedle device
JP6392250B2 (ja) * 2013-02-15 2018-09-19 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 生体内分解性の内部人工器官およびそれに使用する生体内分解性マグネシウム合金を加工する方法
CA2906419C (en) * 2013-03-14 2021-07-06 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate
CN103203072B (zh) * 2013-03-25 2015-05-20 清华大学 金属微针阵列柔性贴片、经皮给药器件及经皮给药贴片
CN105126240A (zh) * 2014-06-03 2015-12-09 陈彦彪 一种可降解超微针片
KR101703050B1 (ko) 2014-07-10 2017-02-07 주식회사 주빅 경피전달용 미세돌기 구조체
CN104212998B (zh) * 2014-08-21 2017-02-01 北京大学 一种Zn‑Mg系锌合金及其制备方法与应用
KR101785766B1 (ko) 2014-11-14 2017-10-18 가천대학교 산학협력단 코팅 마이크로니들의 생산 방법 및 그 방법에 의하여 생산된 코팅 마이크로니들
WO2016149152A1 (en) * 2015-03-13 2016-09-22 The University Of North Carolina At Chapel Hill Polymeric microneedles and rapid additive manufacturing of the same
KR101622388B1 (ko) 2015-10-21 2016-05-19 한국과학기술원 실리콘 마이크로 니들 스탬프 및 그 제조방법
KR20170115429A (ko) * 2016-04-07 2017-10-17 랩앤피플주식회사 생체분해성 금속을 이용한 마이크로 니들

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