PL3273968T3 - Związki minocykliny do ochrony biologicznej - Google Patents

Związki minocykliny do ochrony biologicznej

Info

Publication number
PL3273968T3
PL3273968T3 PL16769622.8T PL16769622T PL3273968T3 PL 3273968 T3 PL3273968 T3 PL 3273968T3 PL 16769622 T PL16769622 T PL 16769622T PL 3273968 T3 PL3273968 T3 PL 3273968T3
Authority
PL
Poland
Prior art keywords
biodefense
minocycline compounds
minocycline
compounds
Prior art date
Application number
PL16769622.8T
Other languages
English (en)
Inventor
Michael P. Draper
S. Ken Tanaka
Original Assignee
Paratek Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharmaceuticals, Inc. filed Critical Paratek Pharmaceuticals, Inc.
Publication of PL3273968T3 publication Critical patent/PL3273968T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL16769622.8T 2015-03-24 2016-03-23 Związki minocykliny do ochrony biologicznej PL3273968T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562137719P 2015-03-24 2015-03-24
PCT/US2016/023807 WO2016154332A1 (en) 2015-03-24 2016-03-23 Minocycline compounds for biodefense

Publications (1)

Publication Number Publication Date
PL3273968T3 true PL3273968T3 (pl) 2024-01-03

Family

ID=56977663

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16769622.8T PL3273968T3 (pl) 2015-03-24 2016-03-23 Związki minocykliny do ochrony biologicznej

Country Status (14)

Country Link
US (4) US20180133231A1 (pl)
EP (2) EP3273968B1 (pl)
JP (3) JP6826582B2 (pl)
KR (2) KR20240051297A (pl)
CN (2) CN107613988A (pl)
AU (4) AU2016235151A1 (pl)
CA (1) CA2980727C (pl)
ES (1) ES2959665T3 (pl)
FI (1) FI3273968T3 (pl)
HU (1) HUE063795T2 (pl)
IL (1) IL254622B2 (pl)
MX (1) MX2017012073A (pl)
PL (1) PL3273968T3 (pl)
WO (1) WO2016154332A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017012073A (es) 2015-03-24 2018-02-21 Paratek Pharm Innc Compuestos de minociclina para biodefensas.
CN109154685B (zh) * 2016-03-31 2022-04-19 日产化学株式会社 配向层形成组合物
TW202206081A (zh) * 2016-08-03 2022-02-16 美商派瑞泰Spv2有限公司 9—胺甲基米諾四環素化合物及其用途
RU2019113715A (ru) 2016-11-01 2020-12-03 Паратек Фармасьютикалс, Инк. 9-аминометилминоциклиновые соединения и их применение для лечениия внебольничной бактериальной пневмонии(вбп)
CN111484424B (zh) * 2020-04-14 2022-10-25 成都百特万合医药科技有限公司 一种合成奥马环素的方法
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas
CN114591216A (zh) * 2022-02-17 2022-06-07 四川澄华生物科技有限公司 一种合成奥马环素中间体的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE544745T1 (de) 2000-07-07 2012-02-15 Tufts College 9-substituierte minocyclinverbindungen
WO2011101710A1 (en) * 2010-02-16 2011-08-25 Wockhardt Research Centre Efflux pump inhibitors
US7553828B2 (en) 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
US20040014731A1 (en) * 2002-03-29 2004-01-22 Golub Lorne M. Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins
WO2006071685A2 (en) * 2004-12-20 2006-07-06 Massachusetts Institute Of Technology Antimicrobial combination therapy comprising an antibiotic and toxic compound selected from dna damaging agents, alkylating agents, heavy metal containing compounds and chelating agents
WO2007092582A2 (en) * 2006-02-08 2007-08-16 Biosynexus Incorporated Neutralization of bacterial spores
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
JP2010525069A (ja) 2007-04-27 2010-07-22 パラテック ファーマシューティカルズ インコーポレイテッド アミノアルキルテトラサイクリン化合物の合成方法および精製方法
US20090253660A1 (en) * 2008-03-05 2009-10-08 Paratek Pharmaceuticals, Inc. Minocycline Compounds and Methods of Use Thereof
EP2849757A4 (en) * 2012-05-14 2015-11-18 Paratek Pharm Innc PROCESS FOR USE OF (4S, 4AS, 5AR, 12AS -) - 4-DIMETHYLAMINO-3,10,12,12A-TETRAHYDROXY-7 - [(METHOXY (METHYL) AMINO) -METHYL] -1,11-DIOXO-1 , 4.4A, 5.5A, 6,11,12a-octahydro-naphthacene-2-carboxylic acid amide
MX2017012073A (es) 2015-03-24 2018-02-21 Paratek Pharm Innc Compuestos de minociclina para biodefensas.

Also Published As

Publication number Publication date
KR102656263B1 (ko) 2024-04-09
KR20170138439A (ko) 2017-12-15
EP4268897A3 (en) 2024-01-03
JP2021059544A (ja) 2021-04-15
MX2017012073A (es) 2018-02-21
ES2959665T3 (es) 2024-02-27
EP4268897A2 (en) 2023-11-01
US20200330489A1 (en) 2020-10-22
CN116392496A (zh) 2023-07-07
US20180133231A1 (en) 2018-05-17
KR20240051297A (ko) 2024-04-19
CA2980727A1 (en) 2016-09-29
FI3273968T3 (fi) 2023-10-09
HUE063795T2 (hu) 2024-01-28
EP3273968A1 (en) 2018-01-31
IL254622B1 (en) 2023-09-01
AU2020260450A1 (en) 2020-12-03
AU2022256106A1 (en) 2022-11-24
EP3273968A4 (en) 2018-11-14
JP2018509475A (ja) 2018-04-05
CA2980727C (en) 2023-09-19
IL254622B2 (en) 2024-01-01
US11129839B2 (en) 2021-09-28
US20240238315A1 (en) 2024-07-18
WO2016154332A1 (en) 2016-09-29
CN107613988A (zh) 2018-01-19
AU2024202788A1 (en) 2024-05-23
JP6826582B2 (ja) 2021-02-03
IL254622A0 (en) 2017-11-30
EP3273968B1 (en) 2023-07-19
AU2016235151A1 (en) 2017-10-12
AU2020260450B2 (en) 2022-07-21
US20230098554A1 (en) 2023-03-30
JP2023022179A (ja) 2023-02-14

Similar Documents

Publication Publication Date Title
GB201510019D0 (en) Compounds
IL254622B1 (en) Minocycline compounds for biodefense
GB201514754D0 (en) Compounds
GB201514751D0 (en) Compounds
GB201508747D0 (en) Compounds
HUE054351T2 (hu) Vegyületek
GB201520500D0 (en) Compounds
GB201508864D0 (en) Compounds
IL253813A0 (en) Compounds of the diaza-benzofluoroanthrene type and preparations containing these compounds
HUE052932T2 (hu) Vegyületek
GB201510493D0 (en) Compounds
GB201520419D0 (en) Compounds
GB201521682D0 (en) Compounds
GB201508857D0 (en) Compounds
GB201503926D0 (en) Compounds
GB201501115D0 (en) Compounds
GB201520189D0 (en) Compound for use
GB201522246D0 (en) Compounds
GB201521912D0 (en) Compounds
GB201521440D0 (en) Compounds
GB201521086D0 (en) Compounds
GB201519969D0 (en) Compounds
GB201519965D0 (en) Compounds
GB201519212D0 (en) Compounds
GB201519213D0 (en) Compounds