PL314484A1 - Derivatives of pyrone as protease inhibitors and antiviral agents - Google Patents
Derivatives of pyrone as protease inhibitors and antiviral agentsInfo
- Publication number
- PL314484A1 PL314484A1 PL94314484A PL31448494A PL314484A1 PL 314484 A1 PL314484 A1 PL 314484A1 PL 94314484 A PL94314484 A PL 94314484A PL 31448494 A PL31448494 A PL 31448494A PL 314484 A1 PL314484 A1 PL 314484A1
- Authority
- PL
- Poland
- Prior art keywords
- pyrone
- derivatives
- protease inhibitors
- antiviral agents
- antiviral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15502893A | 1993-11-19 | 1993-11-19 | |
| US08/319,768 US5808062A (en) | 1993-11-19 | 1994-10-12 | Pyrone derivatives as protease inhibitors and antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL314484A1 true PL314484A1 (en) | 1996-09-16 |
Family
ID=26851948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL94314484A PL314484A1 (en) | 1993-11-19 | 1994-10-26 | Derivatives of pyrone as protease inhibitors and antiviral agents |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0729466A1 (en) |
| JP (1) | JPH09505295A (en) |
| AU (1) | AU682417B2 (en) |
| BG (1) | BG62770B1 (en) |
| CA (1) | CA2174124A1 (en) |
| CZ (1) | CZ134396A3 (en) |
| EE (1) | EE9600044A (en) |
| FI (1) | FI962019A (en) |
| HR (1) | HRP940938A2 (en) |
| HU (1) | HUT74888A (en) |
| IL (1) | IL111671A0 (en) |
| NO (1) | NO962015D0 (en) |
| PL (1) | PL314484A1 (en) |
| RU (1) | RU2153497C2 (en) |
| SK (1) | SK63996A3 (en) |
| WO (1) | WO1995014014A2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW587079B (en) | 1998-09-25 | 2004-05-11 | Almirall Prodesfarma Ag | 2-phenylpyran-4-one derivatives |
| ES2154561B1 (en) * | 1998-09-25 | 2001-12-01 | Almirall Prodesfarma Sa | DERIVATIVES OF 2-FENILPIRAN-4-ONA. |
| ES2168895A1 (en) * | 1999-03-26 | 2002-06-16 | Almirall Prodesfarma Sa | 2-Phenylpyran-4-one derivatives as cyclooxygenase-2 (COX-2) inhibitors useful e.g. for treating pain, fever or inflammation, preventing colorectal cancer or neurodegenerative diseases |
| PE20011333A1 (en) * | 2000-03-16 | 2002-01-16 | Almirall Prodesfarma Ag | DERIVATIVES OF 2-FENYLPYRAN-4-ONA AS INHIBITORS OF CYCLOOXYGENASE 2 |
| ES2844184T3 (en) * | 2016-06-14 | 2021-07-21 | Bristol Myers Squibb Co | 4-hydroxy-3-sulfonylpyridine-2 (1H) -ones as APJ receptor agonists |
| WO2017218633A1 (en) * | 2016-06-14 | 2017-12-21 | Bristol-Myers Squibb Company | 6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1h)-one as apj agonists |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3724M (en) * | 1963-12-04 | 1965-12-06 | Marcel Perrault | Medicinal product based on anisoyl-3 hydroxy-4 p. methoxy-phenyl-6α-pyrone. |
| US3818046A (en) * | 1972-12-18 | 1974-06-18 | Dow Chemical Co | Sulfur-containing hydroxy pyrones and alkali metal salts thereof |
| DE4308451A1 (en) * | 1992-09-10 | 1994-04-14 | Bayer Ag | 3-aryl-pyrone derivatives |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
| JP3372338B2 (en) * | 1994-02-14 | 2003-02-04 | オリンパス光学工業株式会社 | Distance measuring device |
-
1994
- 1994-10-26 CA CA002174124A patent/CA2174124A1/en not_active Abandoned
- 1994-10-26 JP JP7514461A patent/JPH09505295A/en active Pending
- 1994-10-26 EP EP95900457A patent/EP0729466A1/en not_active Withdrawn
- 1994-10-26 EE EE9600044A patent/EE9600044A/en unknown
- 1994-10-26 SK SK639-96A patent/SK63996A3/en unknown
- 1994-10-26 PL PL94314484A patent/PL314484A1/en unknown
- 1994-10-26 WO PCT/US1994/012367 patent/WO1995014014A2/en not_active Application Discontinuation
- 1994-10-26 HU HU9601347A patent/HUT74888A/en unknown
- 1994-10-26 AU AU81276/94A patent/AU682417B2/en not_active Ceased
- 1994-10-26 RU RU96113056/04A patent/RU2153497C2/en active
- 1994-10-26 CZ CZ961343A patent/CZ134396A3/en unknown
- 1994-11-17 IL IL11167194A patent/IL111671A0/en unknown
- 1994-11-18 HR HR08/319,768A patent/HRP940938A2/en not_active Application Discontinuation
-
1996
- 1996-05-03 BG BG100564A patent/BG62770B1/en unknown
- 1996-05-13 FI FI962019A patent/FI962019A/en unknown
- 1996-05-15 NO NO962015A patent/NO962015D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EE9600044A (en) | 1996-10-15 |
| HRP940938A2 (en) | 1997-06-30 |
| NO962015L (en) | 1996-05-15 |
| FI962019A0 (en) | 1996-05-13 |
| BG62770B1 (en) | 2000-07-31 |
| AU8127694A (en) | 1995-06-06 |
| BG100564A (en) | 1996-12-31 |
| JPH09505295A (en) | 1997-05-27 |
| HUT74888A (en) | 1997-02-28 |
| WO1995014014A2 (en) | 1995-05-26 |
| CZ134396A3 (en) | 1996-08-14 |
| WO1995014014A3 (en) | 1995-06-15 |
| NO962015D0 (en) | 1996-05-15 |
| HU9601347D0 (en) | 1996-07-29 |
| IL111671A0 (en) | 1995-01-24 |
| EP0729466A1 (en) | 1996-09-04 |
| CA2174124A1 (en) | 1995-05-26 |
| RU2153497C2 (en) | 2000-07-27 |
| FI962019A (en) | 1996-05-20 |
| SK63996A3 (en) | 1996-11-06 |
| AU682417B2 (en) | 1997-10-02 |
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