PL312426A1 - Bicyclic tetrahydropyrazolepyridines - Google Patents
Bicyclic tetrahydropyrazolepyridinesInfo
- Publication number
- PL312426A1 PL312426A1 PL94312426A PL31242694A PL312426A1 PL 312426 A1 PL312426 A1 PL 312426A1 PL 94312426 A PL94312426 A PL 94312426A PL 31242694 A PL31242694 A PL 31242694A PL 312426 A1 PL312426 A1 PL 312426A1
- Authority
- PL
- Poland
- Prior art keywords
- tetrahydropyrazolepyridines
- bicyclic
- bicyclic tetrahydropyrazolepyridines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8829293A | 1993-07-06 | 1993-07-06 | |
PCT/IB1994/000156 WO1995001980A1 (en) | 1993-07-06 | 1994-06-16 | Bicyclic tetrahydro pyrazolopyridines |
Publications (1)
Publication Number | Publication Date |
---|---|
PL312426A1 true PL312426A1 (en) | 1996-04-29 |
Family
ID=22210524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL94312426A PL312426A1 (en) | 1993-07-06 | 1994-06-16 | Bicyclic tetrahydropyrazolepyridines |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0707585A1 (en) |
JP (1) | JP2944048B2 (en) |
KR (1) | KR100228949B1 (en) |
CN (1) | CN1048015C (en) |
AU (1) | AU695301B2 (en) |
BR (1) | BR9406946A (en) |
CA (1) | CA2166721C (en) |
CZ (1) | CZ3696A3 (en) |
EG (1) | EG20513A (en) |
FI (1) | FI943208A (en) |
HU (1) | HUT74170A (en) |
IL (1) | IL110175A (en) |
MX (1) | MX9405132A (en) |
NO (1) | NO305029B1 (en) |
NZ (1) | NZ266525A (en) |
PL (1) | PL312426A1 (en) |
RU (1) | RU2131876C1 (en) |
TW (1) | TW316904B (en) |
WO (1) | WO1995001980A1 (en) |
ZA (1) | ZA944844B (en) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU702105B2 (en) * | 1994-10-20 | 1999-02-11 | Pfizer Inc. | Bicyclic tetrahydro pyrazolopyridines and their use as medicaments |
SK282167B6 (en) * | 1995-06-06 | 2001-11-06 | Pfizer Inc. | Tricyclic 5,6-dihydro-9h-pyrazol[3,4-c]-1,2,4-triazolo[4,3-a] pyridines and pharmaceutical preparation based on them |
AP932A (en) * | 1996-08-26 | 2001-02-02 | Pfizer | Tricyclic 5,6-dihydro-9H-pyrazolo (3,4c)-1,2,4,-triazolo (4,3-a) pyridines. |
CN1234031A (en) * | 1996-09-04 | 1999-11-03 | 辉瑞大药厂 | Indazole derivatives and their use as inhibitors of phosphodiesterase (PDE) type IV and the prodn. of tumor necrosis factor (TNF) |
ES2232202T3 (en) | 1998-12-23 | 2005-05-16 | Bristol-Myers Squibb Pharma Company | HETEROBICICLES CONTAINING NITROGEN AS INHIBITORS OF THE XA FACTOR. |
US6858616B2 (en) | 1998-12-23 | 2005-02-22 | Bristol-Myers Squibb Pharma Company | Nitrogen containing heterobicycles as factor Xa inhibitors |
US6326495B2 (en) | 1999-04-30 | 2001-12-04 | Pfizer Inc. | Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein |
EP2193808A1 (en) | 1999-08-21 | 2010-06-09 | Nycomed GmbH | Synergistic combination |
TWI243055B (en) * | 2000-04-13 | 2005-11-11 | Nippon Zoki Pharmaceutical Co | Pharmaceutical composition for use in treatment of dermatitis |
BR0113176A (en) * | 2000-08-10 | 2003-06-17 | Pharmacia Italia Spa | Bicyclo-pyrazole compounds, pharmaceutical compositions comprising the compounds, use of the compounds in the manufacture of medicaments, processes for the preparation of the compounds, combinatorial chemical collection and methods for the treatment of mammals including humans using the compounds. |
US6960595B2 (en) * | 2001-03-23 | 2005-11-01 | Bristol-Myers Squibb Pharma Company | 5-6 to 5-7 Heterobicycles as factor Xa inhibitors |
CA2441772A1 (en) | 2001-04-18 | 2002-10-31 | Bristol-Myers Squibb Company | 1,4,5,6-tetrahydropyrazolo-¬3,4-c|-pyridin-7-ones as factor xa inhibitors |
WO2002085356A1 (en) | 2001-04-18 | 2002-10-31 | Bristol-Myers Squibb Company | 1, 4, 5, 6-tetrahydropyrazolo-[3, 4-c]-pyrid in-7-ones as factor xa inhibitors |
JP4196678B2 (en) | 2001-04-26 | 2008-12-17 | 味の素株式会社 | Heterocyclic compounds |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
EP1611131B1 (en) | 2003-02-27 | 2010-09-15 | Palau Pharma, S.A. | Pyrazolopyridine derivates |
US7135469B2 (en) * | 2003-03-18 | 2006-11-14 | Bristol Myers Squibb, Co. | Linear chain substituted monocyclic and bicyclic derivatives as factor Xa inhibitors |
EA200501548A1 (en) | 2003-04-01 | 2006-02-24 | Апплайд Резеч Системз Арс Холдинг Н.В. | PHOSPHODYSTERASE INHIBITORS FOR INFERTILITY |
US7145012B2 (en) | 2003-04-23 | 2006-12-05 | Pfizer Inc. | Cannabinoid receptor ligands and uses thereof |
DE102005031580A1 (en) * | 2005-07-06 | 2007-01-11 | Aicuris Gmbh & Co. Kg | Substituted sulfolanylpyrazoles and their use |
AR065804A1 (en) * | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | COMPOSITE OF INDOL CARBOXAMIDE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND USE OF THIS COMPOUND TO PREPARE A MEDICINAL PRODUCT |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EA020466B1 (en) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
WO2012118972A2 (en) | 2011-03-01 | 2012-09-07 | Synegy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
WO2014131024A2 (en) | 2013-02-25 | 2014-08-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
CN113388007A (en) | 2013-06-05 | 2021-09-14 | 博士医疗爱尔兰有限公司 | Ultra-pure agonists of guanylate cyclase C, methods of making and using the same |
MX2016001714A (en) | 2013-08-09 | 2016-10-03 | Ardelyx Inc | Compounds and methods for inhibiting phosphate transport. |
CN110357888A (en) * | 2018-04-09 | 2019-10-22 | 南京药捷安康生物科技有限公司 | Heterocycle phosphodiesterase inhibitors and application thereof |
US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3340269A (en) * | 1964-09-08 | 1967-09-05 | Ciba Geigy Corp | 1-substituted 4-acyl-2, 3-dioxo-piperidine |
US3365459A (en) * | 1964-09-08 | 1968-01-23 | Ciba Geigy Corp | Certain tetrahydro pyrazolo-pyridine and pyrazolo-piperidine derivatives |
FR1463883A (en) * | 1964-09-08 | 1966-07-22 | Ciba Geigy | Process for the preparation of bicyclic triaza-compounds |
US5356897A (en) * | 1991-09-09 | 1994-10-18 | Fujisawa Pharmaceutical Co., Ltd. | 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines |
-
1994
- 1994-06-16 NZ NZ266525A patent/NZ266525A/en unknown
- 1994-06-16 JP JP7503938A patent/JP2944048B2/en not_active Expired - Lifetime
- 1994-06-16 AU AU68057/94A patent/AU695301B2/en not_active Ceased
- 1994-06-16 EP EP94916370A patent/EP0707585A1/en not_active Withdrawn
- 1994-06-16 CN CN94193233A patent/CN1048015C/en not_active Expired - Fee Related
- 1994-06-16 WO PCT/IB1994/000156 patent/WO1995001980A1/en not_active Application Discontinuation
- 1994-06-16 KR KR1019960700019A patent/KR100228949B1/en not_active IP Right Cessation
- 1994-06-16 CZ CZ9636A patent/CZ3696A3/en unknown
- 1994-06-16 PL PL94312426A patent/PL312426A1/en unknown
- 1994-06-16 HU HU9503934A patent/HUT74170A/en unknown
- 1994-06-16 BR BR9406946A patent/BR9406946A/en not_active Application Discontinuation
- 1994-06-16 RU RU96103653A patent/RU2131876C1/en active
- 1994-06-16 CA CA002166721A patent/CA2166721C/en not_active Expired - Fee Related
- 1994-06-17 TW TW083105518A patent/TW316904B/zh active
- 1994-06-30 IL IL11017594A patent/IL110175A/en active IP Right Grant
- 1994-07-05 MX MX9405132A patent/MX9405132A/en unknown
- 1994-07-05 EG EG40294A patent/EG20513A/en active
- 1994-07-05 ZA ZA944844A patent/ZA944844B/en unknown
- 1994-07-05 FI FI943208A patent/FI943208A/en unknown
-
1996
- 1996-01-05 NO NO960056A patent/NO305029B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO305029B1 (en) | 1999-03-22 |
JPH08507084A (en) | 1996-07-30 |
CN1048015C (en) | 2000-01-05 |
CA2166721A1 (en) | 1995-01-19 |
NO960056D0 (en) | 1996-01-05 |
AU6805794A (en) | 1995-02-06 |
CN1129940A (en) | 1996-08-28 |
CA2166721C (en) | 1999-07-27 |
IL110175A (en) | 2000-01-31 |
FI943208A (en) | 1995-01-07 |
HU9503934D0 (en) | 1996-03-28 |
BR9406946A (en) | 1996-08-06 |
HUT74170A (en) | 1996-11-28 |
NZ266525A (en) | 1997-10-24 |
MX9405132A (en) | 1995-01-31 |
ZA944844B (en) | 1996-01-05 |
WO1995001980A1 (en) | 1995-01-19 |
TW316904B (en) | 1997-10-01 |
EG20513A (en) | 1999-06-30 |
FI943208A0 (en) | 1994-07-05 |
CZ3696A3 (en) | 1997-06-11 |
KR100228949B1 (en) | 1999-11-01 |
KR960703852A (en) | 1996-08-31 |
IL110175A0 (en) | 1994-10-07 |
RU2131876C1 (en) | 1999-06-20 |
NO960056L (en) | 1996-01-05 |
AU695301B2 (en) | 1998-08-13 |
JP2944048B2 (en) | 1999-08-30 |
EP0707585A1 (en) | 1996-04-24 |
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