PL310896A1 - Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors - Google Patents
Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitorsInfo
- Publication number
- PL310896A1 PL310896A1 PL94310896A PL31089694A PL310896A1 PL 310896 A1 PL310896 A1 PL 310896A1 PL 94310896 A PL94310896 A PL 94310896A PL 31089694 A PL31089694 A PL 31089694A PL 310896 A1 PL310896 A1 PL 310896A1
- Authority
- PL
- Poland
- Prior art keywords
- compounds useful
- cyclic compounds
- glycoprotein inhibitors
- platelet iib
- iiia glycoprotein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3844893A | 1993-03-29 | 1993-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL310896A1 true PL310896A1 (en) | 1996-01-08 |
Family
ID=21900014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL94310896A PL310896A1 (en) | 1993-03-29 | 1994-03-28 | Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0691987A1 (en) |
JP (1) | JPH08508498A (en) |
AU (1) | AU6415894A (en) |
CA (1) | CA2159070A1 (en) |
FI (1) | FI954556A0 (en) |
HU (1) | HUT72896A (en) |
NO (1) | NO953832L (en) |
NZ (1) | NZ263456A (en) |
PL (1) | PL310896A1 (en) |
WO (1) | WO1994022910A1 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU682857B2 (en) * | 1993-03-29 | 1997-10-23 | Du Pont Pharmaceuticals Company | Novel processes and intermediate compounds for the preparation of platelet clycoprotein IIb/IIIa inhibitors |
US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
AP1390A (en) * | 1996-11-27 | 2005-04-15 | Aventis Pharmaceuticals Products Inc | Pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound. |
US6010911A (en) * | 1997-04-30 | 2000-01-04 | Medtronic, Inc. | Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique |
US6537520B1 (en) | 1998-03-31 | 2003-03-25 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
GB0623607D0 (en) | 2006-11-27 | 2007-01-03 | Haemostatix Ltd | Tissue adhesive |
JP5649825B2 (en) | 2007-01-31 | 2015-01-07 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | Stabilized p53 peptides and methods of use thereof |
ES2430067T3 (en) | 2007-03-28 | 2013-11-18 | President And Fellows Of Harvard College | Sewn polypeptides |
NZ599899A (en) | 2009-11-10 | 2014-10-31 | Allegro Pharmaceuticals Inc | Compositions and methods for inhibiting cellular adhesion or directing diagnostic or therapeutic agents to rgd binding sites |
US11673914B2 (en) | 2009-11-10 | 2023-06-13 | Allegro Pharmaceuticals, LLC | Peptide therapies for reduction of macular thickening |
KR20170058446A (en) | 2010-08-13 | 2017-05-26 | 에일러론 테라퓨틱스 인코포레이티드 | Peptidomimetic macrocycles |
ES2820855T3 (en) | 2011-05-09 | 2021-04-22 | Allegro Pharmaceuticals Llc | Integrin receptor antagonists and their methods of use |
RU2639523C2 (en) | 2011-10-18 | 2017-12-21 | Эйлерон Терапьютикс, Инк. | Peptidomimetic macrocycles and their application |
CA2864120A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
CA2862038C (en) | 2012-02-15 | 2021-05-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
JP6526563B2 (en) | 2012-11-01 | 2019-06-05 | エイルロン セラピューティクス,インコーポレイテッド | Disubstituted amino acids and methods for their preparation and use |
CA2961029A1 (en) | 2014-09-24 | 2016-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
MX2017003797A (en) | 2014-09-24 | 2017-06-15 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof. |
CN107614003A (en) | 2015-03-20 | 2018-01-19 | 艾瑞朗医疗公司 | Peptidomimetic macrocyclic compound and application thereof |
US10023613B2 (en) | 2015-09-10 | 2018-07-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of MCL-1 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2636066B1 (en) * | 1988-09-02 | 1991-10-25 | Centre Nat Rech Scient | CYCLOPEPTIDE DERIVATIVES FOR USE AS SELECTIVE INHIBITORS AGAINST ACTIVE SERINE PROTEASES |
US5384309A (en) * | 1989-07-17 | 1995-01-24 | Genentech, Inc. | Cyclized peptides and their use as platelet aggregation inhibitors |
AU6470590A (en) * | 1989-10-23 | 1991-04-26 | Smithkline Beecham Corporation | Cyclic anti-aggregatory peptides |
IL103252A (en) * | 1991-09-30 | 1997-03-18 | Du Pont Merck Pharma | CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
-
1994
- 1994-03-28 EP EP94911703A patent/EP0691987A1/en not_active Withdrawn
- 1994-03-28 NZ NZ263456A patent/NZ263456A/en not_active IP Right Cessation
- 1994-03-28 CA CA002159070A patent/CA2159070A1/en not_active Abandoned
- 1994-03-28 HU HU9502832A patent/HUT72896A/en unknown
- 1994-03-28 WO PCT/US1994/003223 patent/WO1994022910A1/en not_active Application Discontinuation
- 1994-03-28 JP JP6522195A patent/JPH08508498A/en not_active Ceased
- 1994-03-28 PL PL94310896A patent/PL310896A1/en unknown
- 1994-03-28 AU AU64158/94A patent/AU6415894A/en not_active Abandoned
-
1995
- 1995-09-26 FI FI954556A patent/FI954556A0/en unknown
- 1995-09-28 NO NO953832A patent/NO953832L/en unknown
Also Published As
Publication number | Publication date |
---|---|
HU9502832D0 (en) | 1995-11-28 |
NZ263456A (en) | 1996-11-26 |
HUT72896A (en) | 1996-06-28 |
FI954556A (en) | 1995-09-26 |
CA2159070A1 (en) | 1994-10-13 |
NO953832D0 (en) | 1995-09-28 |
EP0691987A1 (en) | 1996-01-17 |
JPH08508498A (en) | 1996-09-10 |
FI954556A0 (en) | 1995-09-26 |
WO1994022910A1 (en) | 1994-10-13 |
NO953832L (en) | 1995-11-28 |
AU6415894A (en) | 1994-10-24 |
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