PL3027613T3 - Pochodne pirolochinoliny jako antagonisty 5-HT6, sposób wytwarzania i ich zastosowanie - Google Patents
Pochodne pirolochinoliny jako antagonisty 5-HT6, sposób wytwarzania i ich zastosowanieInfo
- Publication number
- PL3027613T3 PL3027613T3 PL13759883T PL13759883T PL3027613T3 PL 3027613 T3 PL3027613 T3 PL 3027613T3 PL 13759883 T PL13759883 T PL 13759883T PL 13759883 T PL13759883 T PL 13759883T PL 3027613 T3 PL3027613 T3 PL 3027613T3
- Authority
- PL
- Poland
- Prior art keywords
- antagonists
- preparation
- pyrroloquinoline derivatives
- pyrroloquinoline
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13759883.5A EP3027613B1 (en) | 2013-07-25 | 2013-07-25 | Pyrroloquinoline derivatives as 5-ht6 antagonists, preparation method and use thereof |
| PCT/PL2013/000097 WO2015012704A1 (en) | 2013-07-25 | 2013-07-25 | Pyrroloquinoline derivatives as 5-ht6 antagonists, preparation method and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3027613T3 true PL3027613T3 (pl) | 2018-10-31 |
Family
ID=49151293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13759883T PL3027613T3 (pl) | 2013-07-25 | 2013-07-25 | Pochodne pirolochinoliny jako antagonisty 5-HT6, sposób wytwarzania i ich zastosowanie |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9676772B2 (pl) |
| EP (1) | EP3027613B1 (pl) |
| JP (1) | JP6267334B2 (pl) |
| KR (1) | KR20160034403A (pl) |
| CN (1) | CN105531272B (pl) |
| AU (1) | AU2013394970B2 (pl) |
| BR (1) | BR112016001545A2 (pl) |
| CA (1) | CA2919147A1 (pl) |
| DK (1) | DK3027613T3 (pl) |
| ES (1) | ES2674476T3 (pl) |
| HR (1) | HRP20180977T1 (pl) |
| HU (1) | HUE038084T2 (pl) |
| LT (1) | LT3027613T (pl) |
| MX (1) | MX363632B (pl) |
| PL (1) | PL3027613T3 (pl) |
| PT (1) | PT3027613T (pl) |
| RS (1) | RS57379B1 (pl) |
| RU (1) | RU2688161C2 (pl) |
| SI (1) | SI3027613T1 (pl) |
| TR (1) | TR201808781T4 (pl) |
| WO (1) | WO2015012704A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6515175B2 (ja) | 2014-07-08 | 2019-05-15 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． | 芳香族ヘテロ環誘導体及びその医薬的適用 |
| EP3377490A1 (en) | 2015-11-16 | 2018-09-26 | Fundacion para la Investigacion Medica Aplicada | Novel compounds as inhibitors of dna methyltransferases |
| WO2019180176A1 (en) | 2018-03-21 | 2019-09-26 | Spherium Biomed, S.L. | Composition for the treatment of schizophrenia and/or psychosis |
| CN115010707B (zh) * | 2021-12-31 | 2023-09-19 | 淮阴师范学院 | 喹啉并吡咯衍生物的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216162A (en) | 1992-08-28 | 1993-06-01 | American Home Products Corporation | Substituted pyrrolo[3,2-c]quinolines |
| GB2316072B (en) | 1996-08-05 | 2000-05-10 | Pharmacia Spa | Pyrrolo[3,2-c]quinoline derivatives |
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| WO2000001696A1 (en) | 1998-07-02 | 2000-01-13 | Korea Research Institute Of Chemical Technology | 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES |
| GB9819019D0 (en) * | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds II |
| US6951881B2 (en) | 2002-05-10 | 2005-10-04 | Wyeth | (1-substituted-indol-3-yl) alkylidenehydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands |
| US7943639B2 (en) * | 2002-06-20 | 2011-05-17 | Proximagen Limited | Compounds |
| EP1641794A1 (en) * | 2003-06-30 | 2006-04-05 | ALTANA Pharma AG | Novel pyrrolodihydroisoquinolines useful in the treatment of cancer |
| GB0322510D0 (en) | 2003-09-25 | 2003-10-29 | Glaxo Group Ltd | Novel compounds |
| GB0522715D0 (en) * | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
| AR062907A1 (es) | 2006-09-22 | 2008-12-17 | Solvay Pharm Bv | Derivados de sulfonilpirazol y sulfonilpirazolincarboxamidina como antagonistas de 5-ht6 |
| EA016456B1 (ru) | 2006-10-30 | 2012-05-30 | Биовитрум Аб (Пабл) | 8-СУЛЬФОНИЛ-1,3,4,8-ТЕТРАГИДРО-2Н-[1,4]ОКСАЗЕПИНО[6,7-e]ИНДОЛЬНЫЕ ПРОИЗВОДНЫЕ И ИХ ИСПОЛЬЗОВАНИЕ В КАЧЕСТВЕ 5-НТРЕЦЕПТОРНЫХ ЛИГАНДОВ |
| DK2155674T3 (da) | 2007-05-03 | 2011-09-26 | Suven Life Sciences Ltd | Aminoalkoxy-aryl-sulfonamidforbindelser og anvendelse heraf som 5-HT6-ligander |
| AU2008256859A1 (en) | 2007-05-24 | 2008-12-04 | Memory Pharmaceuticals Corporation | 4' substituted compounds having 5-HT6 receptor affinity |
| WO2009023844A2 (en) | 2007-08-15 | 2009-02-19 | Memory Pharmaceuticals Corporation | 3' substituted compounds having 5-ht6 receptor affinity |
| AR073574A1 (es) * | 2008-09-10 | 2010-11-17 | Alcon Res Ltd | Inhibidores heterociclicos de los receptores de histamina para el tratamiento de una enfermedad |
| WO2011044134A1 (en) | 2009-10-05 | 2011-04-14 | Albany Molecular Research, Inc. | Epiminocycloalkyl(b)indole derivatives as serotonin sub-type 6 (5-ht6) modulators and uses thereof |
-
2013
- 2013-07-25 CN CN201380078490.0A patent/CN105531272B/zh not_active Expired - Fee Related
- 2013-07-25 RS RS20180713A patent/RS57379B1/sr unknown
- 2013-07-25 WO PCT/PL2013/000097 patent/WO2015012704A1/en active Application Filing
- 2013-07-25 RU RU2016106096A patent/RU2688161C2/ru not_active IP Right Cessation
- 2013-07-25 BR BR112016001545A patent/BR112016001545A2/pt not_active Application Discontinuation
- 2013-07-25 JP JP2016529738A patent/JP6267334B2/ja not_active Expired - Fee Related
- 2013-07-25 TR TR2018/08781T patent/TR201808781T4/tr unknown
- 2013-07-25 LT LTEP13759883.5T patent/LT3027613T/lt unknown
- 2013-07-25 EP EP13759883.5A patent/EP3027613B1/en active Active
- 2013-07-25 DK DK13759883.5T patent/DK3027613T3/en active
- 2013-07-25 KR KR1020167004760A patent/KR20160034403A/ko not_active Application Discontinuation
- 2013-07-25 HU HUE13759883A patent/HUE038084T2/hu unknown
- 2013-07-25 PT PT137598835T patent/PT3027613T/pt unknown
- 2013-07-25 AU AU2013394970A patent/AU2013394970B2/en not_active Ceased
- 2013-07-25 ES ES13759883.5T patent/ES2674476T3/es active Active
- 2013-07-25 US US14/907,050 patent/US9676772B2/en not_active Expired - Fee Related
- 2013-07-25 PL PL13759883T patent/PL3027613T3/pl unknown
- 2013-07-25 MX MX2016001080A patent/MX363632B/es unknown
- 2013-07-25 SI SI201331078T patent/SI3027613T1/sl unknown
- 2013-07-25 CA CA2919147A patent/CA2919147A1/en not_active Abandoned
-
2017
- 2017-05-05 US US15/588,225 patent/US20170239237A1/en not_active Abandoned
-
2018
- 2018-06-26 HR HRP20180977TT patent/HRP20180977T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20160034403A (ko) | 2016-03-29 |
| CA2919147A1 (en) | 2015-01-29 |
| SI3027613T1 (sl) | 2018-10-30 |
| MX363632B (es) | 2019-03-29 |
| JP2016525542A (ja) | 2016-08-25 |
| AU2013394970B2 (en) | 2017-11-23 |
| HUE038084T2 (hu) | 2018-09-28 |
| EP3027613A1 (en) | 2016-06-08 |
| US9676772B2 (en) | 2017-06-13 |
| BR112016001545A2 (pt) | 2017-08-29 |
| RU2688161C2 (ru) | 2019-05-20 |
| US20170239237A1 (en) | 2017-08-24 |
| DK3027613T3 (en) | 2018-06-25 |
| CN105531272A (zh) | 2016-04-27 |
| MX2016001080A (es) | 2016-06-21 |
| JP6267334B2 (ja) | 2018-01-24 |
| WO2015012704A1 (en) | 2015-01-29 |
| RU2016106096A (ru) | 2017-08-30 |
| TR201808781T4 (tr) | 2018-07-23 |
| US20160159790A1 (en) | 2016-06-09 |
| PT3027613T (pt) | 2018-07-04 |
| CN105531272B (zh) | 2017-12-22 |
| RS57379B1 (sr) | 2018-08-31 |
| HRP20180977T1 (hr) | 2018-08-10 |
| AU2013394970A1 (en) | 2016-03-10 |
| ES2674476T3 (es) | 2018-07-02 |
| LT3027613T (lt) | 2018-07-25 |
| EP3027613B1 (en) | 2018-03-28 |
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