PL2953634T3 - Methods for expansion or depletion of t-regulatory cells - Google Patents

Methods for expansion or depletion of t-regulatory cells

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Publication number
PL2953634T3
PL2953634T3 PL14748807T PL14748807T PL2953634T3 PL 2953634 T3 PL2953634 T3 PL 2953634T3 PL 14748807 T PL14748807 T PL 14748807T PL 14748807 T PL14748807 T PL 14748807T PL 2953634 T3 PL2953634 T3 PL 2953634T3
Authority
PL
Poland
Prior art keywords
depletion
expansion
methods
regulatory cells
regulatory
Prior art date
Application number
PL14748807T
Other languages
Polish (pl)
Inventor
Denise L. Faustman
Original Assignee
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The General Hospital Corporation filed Critical The General Hospital Corporation
Publication of PL2953634T3 publication Critical patent/PL2953634T3/en

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • C12N5/0637Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
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    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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PL14748807T 2013-02-07 2014-02-06 Methods for expansion or depletion of t-regulatory cells PL2953634T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361762136P 2013-02-07 2013-02-07
US201361763217P 2013-02-11 2013-02-11
EP14748807.6A EP2953634B1 (en) 2013-02-07 2014-02-06 Methods for expansion or depletion of t-regulatory cells
PCT/US2014/015101 WO2014124134A1 (en) 2013-02-07 2014-02-06 Methods for expansion or depletion of t-regulatory cells

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PL2953634T3 true PL2953634T3 (en) 2021-11-22

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US (3) US9821010B2 (en)
EP (2) EP3936137A1 (en)
JP (4) JP6367836B2 (en)
DK (1) DK2953634T3 (en)
ES (1) ES2885423T3 (en)
HR (1) HRP20211353T1 (en)
PL (1) PL2953634T3 (en)
PT (1) PT2953634T (en)
WO (1) WO2014124134A1 (en)

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JP2022502076A (en) * 2018-09-18 2022-01-11 メリマック ファーマシューティカルズ インコーポレーティッド Anti-TNFR2 antibody and its use
US20220073634A1 (en) 2018-11-01 2022-03-10 Bioinvent International Ab Novel agonistic anti tnfr2 antibody molecules
JP2022514179A (en) 2018-11-01 2022-02-10 バイオインベント インターナショナル アクティエボラーグ New agonist anti-TNFR2 antibody molecule
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